公开(公告)号：US20230392204A1

公开(公告)日：2023-12-07

申请号：US18233606

申请日：2023-08-14

Applicant: 10x Genomics, Inc.

Inventor： James Michael Chell ,  Marlon Stoeckius ,  Jonathan Alles ,  Caroline Julie Gallant ,  Christina Galonska ,  Layla Katiraee

IPC: C12Q1/6876 ,  C12Q1/6811 ,  C12Q1/25 ,  C12Q1/6816 ,  C12Q1/6841 ,  C12Q1/6851

CPC classification number: C12Q1/6876 ,  C12Q1/6811 ,  C12Q1/25 ,  C12Q1/6816 ,  C12Q1/6841 ,  C12Q1/6851

Abstract: Provided herein are methods of detecting an analyte of interest to interrogate spatial gene expression in a sample using RNA-templated ligation.

公开(公告)号：US11661626B2

公开(公告)日：2023-05-30

申请号：US17882241

申请日：2022-08-05

Applicant: 10x Genomics, Inc.

Inventor： Layla Katiraee ,  Michael Schnall-Levin ,  Christina Galonska ,  Marlon Stoeckius

IPC: C12Q1/6837 ,  C12Q1/6806 ,  C12Q1/6876

CPC classification number: C12Q1/6837 ,  C12Q1/6806 ,  C12Q1/6876 ,  C12Q2600/154

Abstract: Provided herein are methods of identifying a methylation status of an analyte in a biological sample. Also provided herein are methods that combine identifying the methylation status with spatial technology to identify the location of a methylation status in a biological sample.

公开(公告)号：US11560593B2

公开(公告)日：2023-01-24

申请号：US17707189

申请日：2022-03-29

Applicant: 10x Genomics, Inc.

Inventor： James Michael Chell ,  Marlon Stoeckius ,  Jonathan Alles ,  Caroline Julie Gallant ,  Christina Galonska ,  Felice Alessio Bava ,  Layla Katiraee

IPC: C12Q1/6876 ,  C12Q1/6811 ,  C12Q1/25 ,  C12Q1/6816 ,  C12Q1/6841 ,  C12Q1/6851

Abstract: Provided herein are methods of detecting an analyte of interest to interrogate spatial gene expression in a sample using RNA-templated ligation.

公开(公告)号：US11408029B2

公开(公告)日：2022-08-09

申请号：US17573119

申请日：2022-01-11

Applicant: 10x Genomics, Inc.

Inventor： Layla Katiraee ,  Michael Schnall-Levin ,  Christina Galonska ,  Marlon Stoeckius

IPC: C12Q1/6837 ,  C12Q1/6806 ,  C12Q1/6876

Abstract: Provided herein are methods of identifying a methylation status of an analyte in a biological sample. Also provided herein are methods that combine identifying the methylation status with spatial technology to identify the location of a methylation status in a biological sample.

公开(公告)号：US20210348221A1

公开(公告)日：2021-11-11

申请号：US17220529

申请日：2021-04-01

Applicant: 10x Genomics, Inc.

Inventor： James Michael Chell ,  Marlon Stoeckius ,  Jonathan Alles ,  Caroline Julie Gallant ,  Christina Galonska ,  Felice Alessio Bava ,  Layla Katiraee

IPC: C12Q1/6841 ,  C12Q1/6876 ,  C12Q1/6816 ,  C12Q1/6851 ,  C12Q1/25

Abstract: Provided herein are methods of detecting an analyte of interest to interrogate spatial gene expression in a sample using RNA-templated ligation.

公开(公告)号：US11959076B2

公开(公告)日：2024-04-16

申请号：US18448725

申请日：2023-08-11

Applicant: 10x Genomics, Inc.

Inventor： Hanyoup Kim ,  David Sukovich ,  Layla Katiraee ,  Augusto Manuel Tentori

IPC: C12N15/10

CPC classification number: C12N15/1065

Abstract: Provided herein are methods for capturing a connected probe and/or a capture handle sequence to a capture domain of a capture probe.

公开(公告)号：US20230332138A1

公开(公告)日：2023-10-19

申请号：US18140312

申请日：2023-04-27

Applicant: 10x Genomics, Inc.

Inventor： Hanyoup Kim ,  David Sukovich ,  Layla Katiraee ,  Augusto Manuel Tentori ,  Lauren Gutgesell ,  Janine Hensel ,  Seayar Mohabbat

IPC: C12N15/10

CPC classification number: C12N15/1065

Abstract: Provided herein are methods for capturing a connected probe and/or a capture handle sequence to a capture domain of a capture probe.

公开(公告)号：US20230265489A1

公开(公告)日：2023-08-24

申请号：US18179814

申请日：2023-03-07

Applicant: 10x Genomics, Inc.

Inventor： Cedric Uytingco ,  Layla Katiraee ,  Kristen Pham

IPC: C12Q1/6818 ,  C12N5/00 ,  C12Q1/6804 ,  C12Q1/6837 ,  C12Q1/6841 ,  C12Q1/6876 ,  G01N33/50 ,  G01N33/543

CPC classification number: C12Q1/6818 ,  C12N5/0062 ,  C12Q1/6804 ,  C12Q1/6837 ,  C12Q1/6841 ,  C12Q1/6876 ,  G01N33/5023 ,  G01N33/5088 ,  G01N33/54306 ,  C12Q2600/158 ,  G01N2458/10

Abstract: Provided herein are methods for simultaneous spatio-temporal measurement of gene expression and cellular activity.

公开(公告)号：US20230113230A1

公开(公告)日：2023-04-13

申请号：US17976422

申请日：2022-10-28

Applicant: 10x Genomics, Inc.

Inventor： Hanyoup Kim ,  David Sukovich ,  Layla Katiraee ,  Augusto Manuel Tentori ,  Lauren Gutgesell ,  Janine Hensel ,  Seayar Mohabbat

IPC: C12N15/10

Abstract: Provided herein are methods for capturing a connected probe and/or a capture handle sequence to a capture domain of a capture probe.

公开(公告)号：US20230080543A1

公开(公告)日：2023-03-16

申请号：US17882241

申请日：2022-08-05

Applicant: 10x Genomics, Inc.

Inventor： Layla Katiraee ,  Michael Schnall-Levin ,  Christina Galonska ,  Marlon Stoeckius

IPC: C12Q1/6837 ,  C12Q1/6806 ,  C12Q1/6876

Abstract: Provided herein are methods of identifying a methylation status of an analyte in a biological sample. Also provided herein are methods that combine identifying the methylation status with spatial technology to identify the location of a methylation status in a biological sample.