DEVICES FOR DETERMINING FLOW RESERVE WITHIN A LUMINAL ORGAN

    公开(公告)号:US20210219854A1

    公开(公告)日:2021-07-22

    申请号:US17159114

    申请日:2021-01-26

    申请人: 3DT Holdings, LLC

    发明人: Ghassan S. Kassab

    摘要: Devices, systems, and methods to determine fractional flow reserve. At least one method for determining fractional flow reserve of the present disclosure comprises the steps positioning a device comprising at least two sensors within a luminal organ at or near a stenosis, wherein the at least two sensors are separated a predetermined distance from one another, operating the device to determine flow velocity of a second fluid introduced into me luminal organ to temporarily displace a first fluid present within the luminal organ, and determining fractional flow reserve at or near the stenosis based upon the flow velocity, a mean aortic pressure within the luminal organ, and at least one cross-sectional area at or near the stenosis. Devices and systems useful for performing such exemplary methods are also disclosed herein.

    Blood filter devices, systems, and methods of using the same to detect the presence of a thrombus within said filter devices

    公开(公告)号:US10765502B2

    公开(公告)日:2020-09-08

    申请号:US15724216

    申请日:2017-10-03

    申请人: 3DT Holdings, LLC

    发明人: Ghassan S. Kassab

    摘要: Blood filter devices, systems, and methods of using the same to detect the presence of a thrombus within said filter devices. A device of the present disclosure for detecting a thrombus or other blood particulate matter of a threshold size within a vessel can comprise a filter having a head and a plurality of legs extending distally therefrom, configured to capture the thrombus or other blood particulate matter of at least a threshold size, and at least one impedance element positioned distal to the head and configured to detect a presence of the thrombus or other blood particulate matter of at least a threshold size within the filter by obtaining data within a bloodstream when the filter is positioned within the bloodstream.

    Methods for generating luminal organ profiles using impedance

    公开(公告)号:US10524685B2

    公开(公告)日:2020-01-07

    申请号:US15269767

    申请日:2016-09-19

    申请人: 3DT Holdings, LLC

    发明人: Ghassan S. Kassab

    摘要: Methods to generate luminal organ profiles using impedance. One embodiment of such a method comprises the steps of introducing an impedance device having at least two detection electrodes positioned in between at least two excitation electrodes into a treatment site of a luminal organ at a first position, measuring a first treatment site conductance at the first position using the impedance device and at least two injections of solutions having different conductivities, moving the impedance device to a second position in the luminal organ, measuring a second treatment site conductance at the second position using the impedance device and the at least two injections of solutions having different conductivities, calculating a first position cross-sectional area using the first treatment site conductance and a second position cross-sectional area using the second treatment site conductance, and constructing a profile of the treatment site.

    LUMINAL ORGAN SIZING DEVICES AND METHODS
    25.
    发明申请

    公开(公告)号:US20190133528A1

    公开(公告)日:2019-05-09

    申请号:US16241922

    申请日:2019-01-07

    申请人: 3DT Holdings, LLC

    摘要: Luminal organ sizing devices and methods. In a method of the present disclosure, the method includes performing a valve replacement procedure using a valve device positioned within a valve annulus or opening of a luminal organ while a system including a balloon configured for inflation is at least partially introduced into a luminal organ so that the balloon is adjacent to a valve annulus or opening.

    METHODS TO OBTAIN CROSS-SECTIONAL AREAS WITHIN LUMINAL ORGANS USING IMPEDANCE

    公开(公告)号:US20170181660A1

    公开(公告)日:2017-06-29

    申请号:US15400737

    申请日:2017-01-06

    申请人: 3DT Holdings, LLC

    发明人: Ghassan S. Kassab

    IPC分类号: A61B5/053 A61B5/107

    摘要: Systems and methods to obtain parallel tissue conductances within luminal organs. In one method embodiment to obtain a parallel tissue conductance within a luminal organ of the present disclosure, the method comprises the steps of introducing at least part of a detection device into a luminal organ at a first location, the detection device having a detector, applying current to the detection device using a stimulator, and introducing a first signal having a first frequency and a second signal having a second frequency through the detection device.