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公开(公告)号:US20210219854A1
公开(公告)日:2021-07-22
申请号:US17159114
申请日:2021-01-26
申请人: 3DT Holdings, LLC
发明人: Ghassan S. Kassab
IPC分类号: A61B5/0215 , A61B5/0275 , A61B5/02 , A61B5/0295 , A61B5/026 , A61B5/00
摘要: Devices, systems, and methods to determine fractional flow reserve. At least one method for determining fractional flow reserve of the present disclosure comprises the steps positioning a device comprising at least two sensors within a luminal organ at or near a stenosis, wherein the at least two sensors are separated a predetermined distance from one another, operating the device to determine flow velocity of a second fluid introduced into me luminal organ to temporarily displace a first fluid present within the luminal organ, and determining fractional flow reserve at or near the stenosis based upon the flow velocity, a mean aortic pressure within the luminal organ, and at least one cross-sectional area at or near the stenosis. Devices and systems useful for performing such exemplary methods are also disclosed herein.
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公开(公告)号:US10765502B2
公开(公告)日:2020-09-08
申请号:US15724216
申请日:2017-10-03
申请人: 3DT Holdings, LLC
发明人: Ghassan S. Kassab
摘要: Blood filter devices, systems, and methods of using the same to detect the presence of a thrombus within said filter devices. A device of the present disclosure for detecting a thrombus or other blood particulate matter of a threshold size within a vessel can comprise a filter having a head and a plurality of legs extending distally therefrom, configured to capture the thrombus or other blood particulate matter of at least a threshold size, and at least one impedance element positioned distal to the head and configured to detect a presence of the thrombus or other blood particulate matter of at least a threshold size within the filter by obtaining data within a bloodstream when the filter is positioned within the bloodstream.
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公开(公告)号:US10524685B2
公开(公告)日:2020-01-07
申请号:US15269767
申请日:2016-09-19
申请人: 3DT Holdings, LLC
发明人: Ghassan S. Kassab
摘要: Methods to generate luminal organ profiles using impedance. One embodiment of such a method comprises the steps of introducing an impedance device having at least two detection electrodes positioned in between at least two excitation electrodes into a treatment site of a luminal organ at a first position, measuring a first treatment site conductance at the first position using the impedance device and at least two injections of solutions having different conductivities, moving the impedance device to a second position in the luminal organ, measuring a second treatment site conductance at the second position using the impedance device and the at least two injections of solutions having different conductivities, calculating a first position cross-sectional area using the first treatment site conductance and a second position cross-sectional area using the second treatment site conductance, and constructing a profile of the treatment site.
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公开(公告)号:US10463274B2
公开(公告)日:2019-11-05
申请号:US15115586
申请日:2015-01-30
申请人: 3DT Holdings, LLC
发明人: Ghassan S. Kassab , Chris Minar , Orhan Soykan , William Combs
IPC分类号: A61B5/02 , A61B5/053 , A61B5/00 , A61B5/01 , A61B5/0215 , A61B5/107 , A61B5/0205 , A61B5/026 , A61B5/027 , A61B5/03
摘要: Impedance devices with integrated circuit modules and method of using the same to obtain luminal organ information. In one embodiment, a device comprises an elongated body for at least partial insertion into a mammalian luminal organ and having a first conductor extending therethrough, a proximal electrical unit connected to the elongated body to deliver power along the first conductor, and a sensor substrate located at or near a distal end of the elongated body and comprising a circuit module operable and/or configured to direct the sizing portion to obtain sizing data and the pressure sensor to obtain pressure data, and facilitate transmission of the sizing data and/or the pressure data to the proximal electrical unit.
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公开(公告)号:US20190133528A1
公开(公告)日:2019-05-09
申请号:US16241922
申请日:2019-01-07
申请人: 3DT Holdings, LLC
发明人: Ghassan S. Kassab , Joanna Mleczko
摘要: Luminal organ sizing devices and methods. In a method of the present disclosure, the method includes performing a valve replacement procedure using a valve device positioned within a valve annulus or opening of a luminal organ while a system including a balloon configured for inflation is at least partially introduced into a luminal organ so that the balloon is adjacent to a valve annulus or opening.
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26.
公开(公告)号:US20180333072A1
公开(公告)日:2018-11-22
申请号:US16050270
申请日:2018-07-31
申请人: 3DT Holdings, LLC
发明人: Ghassan S. Kassab , Mark Svendsen , John Browder
IPC分类号: A61B5/053 , A61B5/00 , A61B5/107 , A61B17/00 , A61B5/01 , A61B18/22 , A61B5/06 , A61B5/0215 , A61B17/22 , A61B5/02
CPC分类号: A61B5/0538 , A61B5/01 , A61B5/02007 , A61B5/02158 , A61B5/065 , A61B5/1076 , A61B5/6853 , A61B5/7278 , A61B2017/00026 , A61B2017/00084 , A61B2017/22051 , A61B2018/2238
摘要: Single injection methods for obtaining conductance measurements within luminal organs using impedance devices. In at least one method embodiment, the method is performed by introducing at least part of an impedance device into a mammalian luminal organ, the impedance device comprising an elongated body and a detector positioned along the elongated body, obtaining conductance measurements indicative of a fluid native to the mammalian luminal organ and indicative of a fluid injection while the detector is present within and outside of the lumen of the outer sheath, and calculating a size parameter of the mammalian luminal organ based in part upon some of the obtained conductance measurements.
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公开(公告)号:US20180200095A1
公开(公告)日:2018-07-19
申请号:US15819657
申请日:2017-11-21
申请人: 3DT Holdings, LLC
发明人: Ghassan S. Kassab , Xiao Lu
IPC分类号: A61F5/00
CPC分类号: A61F5/0076 , A61F5/005 , A61F5/0079
摘要: Intestinal devices and methods for facilitating weight loss. In at least one embodiment of a method of patient treatment of the present disclosure, the method comprises the step of positioning a device, that is configured to reduce or limit localized intestinal distension, around a portion of an intestine of a patient.
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公开(公告)号:US09872759B2
公开(公告)日:2018-01-23
申请号:US14345252
申请日:2012-09-17
申请人: 3DT Holdings, LLC
发明人: Ghassan S. Kassab
CPC分类号: A61F2/06 , A61B17/12013 , A61B2017/00557 , A61F2/2433 , A61F2/2475 , A61F2002/068 , A61F2240/002
摘要: Devices and methods for assisting valve function, replacing venous valves, and predicting valve treatment successes. In at least one exemplary embodiment of an endograft body configured for expansion within a luminal organ of the present disclosure, the endograft body comprises (a) a first portion having a proximal end defining a proximal end aperture and a distal end defining a distal end aperture, the first portion configured to increase a velocity of fluid flowing therethrough, (b) a second portion having a second portion proximal end defining a second portion proximal end aperture and a second portion distal end defining a second portion distal end aperture.
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公开(公告)号:US20170196476A1
公开(公告)日:2017-07-13
申请号:US15470958
申请日:2017-03-28
申请人: 3DT Holdings, LLC
发明人: Ghassan S. Kassab
IPC分类号: A61B5/053 , A61B5/107 , A61B17/22 , A61B5/00 , A61B18/02 , A61F2/958 , A61M25/10 , A61B5/01 , A61B18/24 , A61B17/3207
摘要: Devices, systems, and methods for removing targeted lesions from vessels. In at least one embodiment of a device for removing a stenotic lesion from a vessel, the device comprises a sizing portion capable of measuring a luminal size parameter when at least part of the device is positioned within a lumen of a luminal organ, a typing portion, wherein at least part of the at least one typing portion is capable of physically touching a portion of the luminal organ or a structure therein, and a treatment portion capable of removing at least part of a stenotic lesion from the luminal organ.
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公开(公告)号:US20170181660A1
公开(公告)日:2017-06-29
申请号:US15400737
申请日:2017-01-06
申请人: 3DT Holdings, LLC
发明人: Ghassan S. Kassab
CPC分类号: A61B5/0538 , A61B5/053 , A61B5/1076
摘要: Systems and methods to obtain parallel tissue conductances within luminal organs. In one method embodiment to obtain a parallel tissue conductance within a luminal organ of the present disclosure, the method comprises the steps of introducing at least part of a detection device into a luminal organ at a first location, the detection device having a detector, applying current to the detection device using a stimulator, and introducing a first signal having a first frequency and a second signal having a second frequency through the detection device.
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