Enzymatic Enantioselective Ester or Amide Hydrolysis or Synthesis
    24.
    发明申请
    Enzymatic Enantioselective Ester or Amide Hydrolysis or Synthesis 审中-公开
    酶对映选择性酯或酰胺水解或合成

    公开(公告)号:US20080138856A1

    公开(公告)日:2008-06-12

    申请号:US11813614

    申请日:2006-02-10

    IPC分类号: C12P21/06 C12P7/62

    摘要: The enantioselectivity of fungal lipolytic enzymes can be altered by substituting a suitably selected amino acid residue. The residue to be substituted is selected from its location in the 3D structure of the enzyme and an ester substrate (or a substrate analogue). A residue in the lid may be selected if it is located close to the acid part or close to the alcohol part of an ester substrate. A residue outside the lid region may be selected if it is located close to the active site or close to the substrate.

    摘要翻译: 真菌脂肪分解酶的对映体选择性可以通过替代适当选择的氨基酸残基来改变。 待取代的残基选自其酶的位置和酯底物(或底物类似物)的3D结构。 如果位于靠近酸性部分或靠近酯基材的醇部分的位置,则可以选择盖子中的残余物。 如果位于靠近活性部位或靠近基底的位置,则可以选择盖子外部的残余物。

    Lipase variants
    26.
    发明申请
    Lipase variants 失效
    脂肪酶变体

    公开(公告)号:US20070161082A1

    公开(公告)日:2007-07-12

    申请号:US11602553

    申请日:2006-11-21

    CPC分类号: C11D3/38627

    摘要: Attaching a peptide extension to the C-terminal amino acid of a lipase reduces the tendency to form odor. This may lead to lipase variants with a reduced odor generation when washing textile soiled with fat which includes relatively short-chain fatty acyl groups (e.g., up to C8) such as dairy stains containing butter fat or tropical oils such as coconut oil or palm kernel oil.

    摘要翻译: 将肽延伸连接到脂肪酶的C末端氨基酸可降低形成气味的倾向。 当洗涤用脂肪污染的纺织品时,可能导致脂肪酶变体具有减少的气味产生,所述脂肪包括相对短链的脂肪酰基(例如高达C 8 N 8),例如含有脂肪或热带 油如椰子油或棕榈仁油。