公开(公告)号：US09439578B2

公开(公告)日：2016-09-13

申请号：US14136378

申请日：2013-12-20

Applicant: Boston Scientific Scimed, Inc.

Inventor： Pramodsingh H. Thakur ,  Shantha Arcot-Krishnamurthy ,  Barun Maskara ,  Sunipa Saha ,  Allan C. Shuros ,  Shibaji Shome

IPC: A61B5/0456 ,  A61B5/0452 ,  A61B5/00 ,  A61N1/37 ,  A61B5/042 ,  A61N1/05

CPC classification number: A61B5/0452 ,  A61B5/04014 ,  A61B5/0422 ,  A61B5/0456 ,  A61B5/6858 ,  A61B5/7203 ,  A61B5/725 ,  A61B5/7282 ,  A61B18/1206 ,  A61B18/1492 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/00595 ,  A61B2018/00642 ,  A61B2018/00839 ,  A61N1/056 ,  A61N1/3702

Abstract: A method for mapping a cardiac chamber includes sensing activation signals of intrinsic physiological activity with a plurality of electrodes disposed in or near the cardiac chamber, the activation signals including a near-field activation signal component and a far-field activation signal component, isolating R-wave events in the activation signals, generating a far-field activation template representative of the far-field activation signal component based on the R-wave events, and filtering the far-field activation template from the activation signals to identify the near-field activation signal components in the activation signals.

Abstract translation: 用于映射心室的方法包括利用布置在心室中或附近的多个电极来感测内在生理活动的激活信号，激活信号包括近场激活信号分量和远场激活信号分量，将R - 激活信号中的波事件，基于R波事件产生表示远场激活信号分量的远场激活模板，以及从激活信号过滤远场激活模板以识别近场 激活信号中的激活信号分量。

公开(公告)号：US09332920B2

公开(公告)日：2016-05-10

申请号：US14134831

申请日：2013-12-19

Applicant: Boston Scientific Scimed, Inc.

Inventor： Pramodsingh H. Thakur ,  Barun Maskara ,  Shantha Arcot-Krishnamurthy ,  Sunipa Saha ,  Shibaji Shome

IPC: A61B5/04 ,  A61B5/042 ,  A61B5/00 ,  A61B5/0464 ,  G06K9/00 ,  A61B18/14 ,  A61B18/00

CPC classification number: A61B5/042 ,  A61B5/0422 ,  A61B5/0464 ,  A61B5/6858 ,  A61B5/7246 ,  A61B18/1492 ,  A61B2018/00357 ,  A61B2018/00577 ,  G06K9/00536 ,  G06K2209/057

Abstract: An anatomical mapping system includes a plurality of mapping electrodes each having an electrode location and configured to detect activation signals of intrinsic physiological activity within an anatomical structure. A mapping processor is associated with the plurality of mapping electrodes and is configured to record the detected activation signals and associate one of the plurality of mapping electrodes with each recorded activation signal. The mapping processor is further configured to analyze the recorded activation signals to identify at least one recurring pattern based on a relationship between a timing of the detected activation signals and the electrode locations of the mapping electrode associated with each detected activation signal.

Abstract translation: 解剖映射系统包括多个映射电极，每个映射电极具有电极位置并且被配置为检测解剖结构内的内在生理活动的激活信号。 映射处理器与多个映射电极相关联，并且被配置为记录检测到的激活信号，并将多个映射电极中的一个与每个记录的激活信号相关联。 映射处理器还被配置为基于检测到的激活信号的定时与与每个检测到的激活信号相关联的映射电极的电极位置之间的关系来分析所记录的激活信号以识别至少一个循环模式。

公开(公告)号：US20140180152A1

公开(公告)日：2014-06-26

申请号：US14136607

申请日：2013-12-20

Applicant: Boston Scientific Scimed, Inc.

Inventor： Barun Maskara ,  Pramodsingh H. Thakur ,  Shantha Arcot-Krishnamurthy ,  Shibaji Shome ,  Sunipa Saha ,  Allan C. Shuros ,  Scott A. Meyer

IPC: A61B5/044 ,  A61B5/00

CPC classification number: A61B5/0538 ,  A61B5/0422 ,  A61B5/0424 ,  A61B5/044 ,  A61B5/6858 ,  A61B5/6885 ,  A61B18/1492 ,  A61B2017/00044 ,  A61B2017/00053 ,  A61B2018/00267 ,  A61B2018/00678 ,  A61B2018/00839 ,  A61B2090/065

Abstract: A catheter system includes a mapping catheter including a plurality of mapping electrodes, each mapping electrode configured to sense signals associated with an anatomical structure. The catheter system further includes a processor operatively coupled to the plurality of mapping electrodes and configured to receive the signals sensed by the plurality of mapping electrodes, characterize the signals sensed by the plurality of mapping electrodes based on amplitudes of the sensed signals, and generate an output of a quality of contact of the plurality of mapping electrodes with the anatomical structure based on the signal characterization.

Abstract translation: 导管系统包括包括多个映射电极的映射导管，每个映射电极被配置为感测与解剖结构相关联的信号。 导管系统还包括可操作地耦合到多个映射电极并且被配置为接收由多个映射电极感测的信号的处理器，基于感测信号的幅度表征由多个映射电极感测的信号，并且生成 基于信号表征，输出多个映射电极与解剖结构的接触质量。

公开(公告)号：US20140180147A1

公开(公告)日：2014-06-26

申请号：US14136583

申请日：2013-12-20

Applicant: Boston Scientific Scimed, Inc.

Inventor： Pramodsingh H. Thakur ,  Barun Maskara ,  Allan C. Shuros ,  Shantha Arcot-Krishnamurthy ,  Shibaji Shome ,  Sunipa Saha

IPC: A61B19/00 ,  A61B5/02

CPC classification number: A61B90/06 ,  A61B5/042 ,  A61B5/0422 ,  A61B18/1492 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2090/061

Abstract: A catheter system includes a mapping catheter having a plurality of splines, each of the plurality of splines including a plurality of mapping electrodes. The system further includes a processor operatively coupled to the plurality of mapping electrodes and configured to receive signals sensed by the plurality of mapping electrodes. The processor is further configured to estimate an interspline distance between adjacent splines in the plurality of splines based on the signals sensed by the mapping electrodes on the adjacent splines.

Abstract translation: 导管系统包括具有多个花键的映射导管，多个花键中的每一个包括多个映射电极。 该系统还包括可操作地耦合到多个映射电极并被配置为接收由多个映射电极感测的信号的处理器。 处理器还被配置为基于由相邻样条线上的映射电极感测的信号来估计多个样条中的相邻样条之间的间距距离。

公开(公告)号：US20130345583A1

公开(公告)日：2013-12-26

申请号：US13923006

申请日：2013-06-20

Applicant: Boston Scientific Scimed, Inc.

Inventor： Pramodsingh Hirasingh Thakur ,  Barun Maskara ,  Allan C. Shuros ,  Sunipa Saha ,  Shibaji Shome

IPC: A61B5/04

CPC classification number: A61B5/04017 ,  A61B5/0422 ,  A61B5/6859 ,  A61B5/7235 ,  A61B8/0883 ,  A61B8/5215 ,  A61B18/1492 ,  A61B2017/00053 ,  A61B2018/00267 ,  A61B2018/00839

Abstract: Electrical activity propagation along an electrode array within a cardiac chamber is reconstructed. Signals from the electrode array are sampled, and the signals are plotted in multi-dimensional space with each axis corresponding to a channel in the electrode array. A covariance matrix of the plotted signals is decomposed to characterize the spread of a data cloud of the signals in the multi-dimensional space. The data cloud is then decorrelated, such as through whitening, to suppress excursions along correlated directions (global activation) and enhance excursions along each axis (local activation).

Abstract translation: 重建沿心室内电极阵列的电活动传播。 来自电极阵列的信号被采样，并且将信号绘制在多维空间中，每个轴对应于电极阵列中的通道。 绘制的信号的协方差矩阵被分解以表征多维空间中的信号的数据云的扩展。 然后将数据云解相关，例如通过白化，以抑制沿着相关方向的偏移（全局激活）并增强沿着每个轴的偏移（局部激活）。

公开(公告)号：US20130345537A1

公开(公告)日：2013-12-26

申请号：US13923020

申请日：2013-06-20

Applicant: Boston Scientific Scimed, Inc.

Inventor： Pramodsingh Hirasingh Thakur ,  Barun Maskara ,  Allan C. Shuros ,  Sunipa Saha ,  Shibaji Shome

IPC: A61B5/042 ,  A61B5/04

CPC classification number: A61B5/0422 ,  A61B5/0044 ,  A61B5/04007 ,  A61B5/04012 ,  A61B5/0402 ,  A61B5/042 ,  A61B5/6859 ,  A61B18/1492

Abstract: Electrical activity propagation along an electrode array within a cardiac chamber is reconstructed. Signals are sampled from the electrode array and the signals are plotted in multi-dimensional space with each axis corresponding to a channel in the electrode array. An excursion direction of global activation in the multi-dimensional space is estimated and a change in vectors of the sampled signals over time is determined. Signals with vectors that change over time in the excursion direction are suppressed.

Abstract translation: 重建沿心室内电极阵列的电活动传播。 信号从电极阵列中采样，并且信号绘制在多维空间中，每个轴对应于电极阵列中的通道。 估计多维空间中全局激活的偏移方向，并确定采样信号随时间的向量变化。 具有沿偏移方向随时间变化的矢量的信号被抑制。

公开(公告)号：US09730600B2

公开(公告)日：2017-08-15

申请号：US14527090

申请日：2014-10-29

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Pramodsingh Hirasingh Thakur ,  Allan C. Shuros ,  Barun Maskara ,  Shibaji Shome ,  Shantha Arcot-Krishnamurthy ,  Sunipa Saha ,  Scott A. Meyer

IPC: A61B5/042 ,  A61B5/046 ,  A61B5/0452 ,  A61B5/0464 ,  A61B5/00 ,  A61B18/14 ,  A61B18/00

CPC classification number: A61B5/042 ,  A61B5/0422 ,  A61B5/0452 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/7246 ,  A61B18/1492 ,  A61B2018/0016 ,  A61B2018/00267 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2018/1465 ,  A61B2018/1467

Abstract: Medical devices and methods for using medical devices are disclosed. An example mapping medical device may include a catheter shaft with a plurality of electrodes. The catheter shaft may be coupled to a processor. The processor may be capable of collecting a first set of signals from a first location, collecting a second set of signals from a second location, characterizing the first set of signals over a first time period, characterizing the second set of signals over a second time period, comparing the first set of signals to the second set of signals and matching a first signal from the first set of signals with a second signal from the second set of signals.

公开(公告)号：US09579034B2

公开(公告)日：2017-02-28

申请号：US14868182

申请日：2015-09-28

Applicant: Boston Scientific Scimed Inc.

Inventor： Pramodsingh H. Thakur ,  Shantha Arcot-Krishnamurthy ,  Allan C. Shuros ,  Shibaji Shome ,  Barun Maskara ,  Sunipa Saha

IPC: A61B5/0452 ,  A61B5/042 ,  A61B5/04 ,  A61B5/00 ,  A61B5/046 ,  A61B18/14 ,  A61B18/00

CPC classification number: A61B5/04525 ,  A61B5/04012 ,  A61B5/0422 ,  A61B5/046 ,  A61B5/6858 ,  A61B5/7246 ,  A61B18/1492 ,  A61B2018/00357 ,  A61B2018/00577

Abstract: An anatomical mapping system and method includes mapping electrodes configured to detect activation signals of cardiac activity. A processing system is configured to record the detected activation signals and generate a vector field for each sensed activation signal during each instance of the physiological activity. The processing system determines an onset time and alternative onset time candidates, identifies an initial vector field template based on a degree of similarity between the initial vector field and a vector field template from a bank of templates, then determines an optimized onset time for each activation signal based on a degree similarity between the onset time candidates and initial vector field template.

Abstract translation: 解剖映射系统和方法包括配置成检测心脏活动的激活信号的映射电极。 处理系统被配置为记录检测到的激活信号，并且在生理活动的每个实例期间为每个感测到的激活信号生成矢量场。 处理系统确定开始时间和替代的开始时间候选，基于来自一组模板的初始矢量场和矢量场模板之间的相似度来识别初始矢量场模板，然后确定每个激活的优化的开始时间 基于起始时间候选和初始矢量场模板之间的度相似度的信号。

公开(公告)号：US09144391B2

公开(公告)日：2015-09-29

申请号：US14279723

申请日：2014-05-16

Applicant: Boston Scientific Scimed Inc.

Inventor： Pramodsingh H. Thakur ,  Shantha Arcot-Krishnamurthy ,  Allan C. Shuros ,  Shibaji Shome ,  Barun Maskara ,  Sunipa Saha

IPC: A61B5/0452 ,  A61B5/042 ,  A61B5/00 ,  A61B5/046 ,  A61B18/14

CPC classification number: A61B5/04525 ,  A61B5/04012 ,  A61B5/0422 ,  A61B5/046 ,  A61B5/6858 ,  A61B5/7246 ,  A61B18/1492 ,  A61B2018/00357 ,  A61B2018/00577

Abstract: An anatomical mapping system and method includes mapping electrodes configured to detect activation signals of cardiac activity. A processing system is configured to record the detected activation signals and generate a vector field for each sensed activation signal during each instance of the physiological activity. The processing system determines an onset time and alternative onset time candidates, identifies an initial vector field template based on a degree of similarity between the initial vector field and a vector field template from a bank of templates, then determines an optimized onset time for each activation signal based on a degree similarity between the onset time candidates and initial vector field template.

Abstract translation: 解剖映射系统和方法包括配置成检测心脏活动的激活信号的映射电极。 处理系统被配置为记录检测到的激活信号，并且在生理活动的每个实例期间为每个感测到的激活信号生成矢量场。 处理系统确定开始时间和替代的开始时间候选，基于来自一组模板的初始矢量场和矢量场模板之间的相似度来识别初始矢量场模板，然后确定每个激活的优化的开始时间 基于起始时间候选和初始矢量场模板之间的度相似度的信号。

公开(公告)号：US20150065836A1

公开(公告)日：2015-03-05

申请号：US14471477

申请日：2014-08-28

Applicant: Boston Scientific Scimed Inc.

Inventor： Pramodsingh Hirasingh Thakur ,  Shibaji Shome ,  Allan C. Shuros ,  Shantha Arcot-Krishnamurthy ,  Barun Maskara ,  Sunipa Saha

IPC: A61B5/042 ,  G06N5/04 ,  G06F19/00

CPC classification number: A61B5/0422 ,  A61B5/6858 ,  A61B5/743 ,  G06F19/00 ,  G06N5/047 ,  G16H50/20

Abstract: A system and method for mapping an anatomical structure includes sensing activation signals of physiological activity with a plurality of mapping electrodes disposed in or near the anatomical structure. Patterns among the sensed activation signals are identified based on a similarity measure generated between each unique pair of identified patterns which are classified into groups based on a correlation between the corresponding pairs of similarity measures. A characteristic representation is determined for each group of similarity measures and displayed as a summary plot of the characteristic representations.

Abstract translation: 用于映射解剖结构的系统和方法包括用设置在解剖结构中或附近的多个映射电极感测生理活动的激活信号。 基于在相应的相似度测量对之间的相关性，基于在识别出的每个唯一的识别图案之间生成的相似性度量来识别感测到的激活信号中的模式，所述相似性度量被分类成组。 确定每组相似性度量的特征表示，并显示为特征表示的总结图。