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1.发明申请公开(公告)号：US20220022952A1
公开(公告)日：2022-01-27
申请号：US17381953
申请日：2021-07-21
Applicant: Boston Scientific Scimed Inc
Inventor： Brendan E. Koop , Andrew L. De Kock , Allan C. Shuros
Abstract: Disclosed herein are apparatus, systems, and methods for ablating tissue in a patient by electroporation. Embodiments generally include an ablation catheter having a hand, a shaft, and an electroporation electrode arrangement. The shaft has a distal end and defines a longitudinal axis of the ablation catheter. The electroporation electrode arrangement is at the distal end of the shaft and is configured to generate a multidirectional electric field when at least one pulse sequence is delivered thereto. The multidirectional electric field includes at least two of the following directions relative to the longitudinal axis: generally axial, circumferential, and transverse. The electroporation electrode arrangement is configured to operatively couple to an electroporation generator that is configured to generate the at least one pulse sequence and is configured to receive the at least one pulse sequence from the electroporation generator.
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2.发明申请公开(公告)号：US20170311834A1
公开(公告)日：2017-11-02
申请号：US15651211
申请日：2017-07-17
Applicant: Boston Scientific Scimed Inc.
Inventor： Pramodsingh Hirasingh Thakur , Shibaji Shome , Allan C. Shuros , Shantha Arcot-Krishnamurthy , Barun Maskara , Sunipa Saha
CPC classification number: A61B5/0422 , A61B5/6858 , A61B5/743 , G06N5/047 , G16H50/20
Abstract: An anatomical mapping system including a plurality of mapping electrodes disposed in or near an anatomical structure and configured to detect activation signals of physiological activity, each of the plurality of mapping electrodes having an electrode location, and a processing system associated with the plurality of mapping electrodes, and configured to record the detected activation signals and associate one of the plurality of mapping electrodes with each recorded activation signal. The processing system further configured to determine a dominant frequency at each electrode location, and determine a wavefront vector at each electrode location based on a difference between the dominant frequency at a first electrode location and the dominant frequency at neighboring electrode locations.
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3.发明授权Artifact cancellation to suppress far-field activation during electrophysiology mapping 有权人工取消在电生理学测绘过程中抑制远场激活公开(公告)号：US09439578B2
公开(公告)日：2016-09-13
申请号：US14136378
申请日：2013-12-20
Applicant: Boston Scientific Scimed, Inc.
Inventor： Pramodsingh H. Thakur , Shantha Arcot-Krishnamurthy , Barun Maskara , Sunipa Saha , Allan C. Shuros , Shibaji Shome
IPC: A61B5/0456 , A61B5/0452 , A61B5/00 , A61N1/37 , A61B5/042 , A61N1/05
CPC classification number: A61B5/0452 , A61B5/04014 , A61B5/0422 , A61B5/0456 , A61B5/6858 , A61B5/7203 , A61B5/725 , A61B5/7282 , A61B18/1206 , A61B18/1492 , A61B2018/00351 , A61B2018/00577 , A61B2018/00595 , A61B2018/00642 , A61B2018/00839 , A61N1/056 , A61N1/3702
Abstract: A method for mapping a cardiac chamber includes sensing activation signals of intrinsic physiological activity with a plurality of electrodes disposed in or near the cardiac chamber, the activation signals including a near-field activation signal component and a far-field activation signal component, isolating R-wave events in the activation signals, generating a far-field activation template representative of the far-field activation signal component based on the R-wave events, and filtering the far-field activation template from the activation signals to identify the near-field activation signal components in the activation signals.
Abstract translation: 用于映射心室的方法包括利用布置在心室中或附近的多个电极来感测内在生理活动的激活信号，激活信号包括近场激活信号分量和远场激活信号分量，将R - 激活信号中的波事件，基于R波事件产生表示远场激活信号分量的远场激活模板，以及从激活信号过滤远场激活模板以识别近场 激活信号中的激活信号分量。
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4.发明授权Method and apparatus for sensing and avoiding cardiac conduction system during valve deployment 有权在阀部署期间感测和避免心脏传导系统的方法和装置公开(公告)号：US08888709B2
公开(公告)日：2014-11-18
申请号：US14024294
申请日：2013-09-11
Applicant: Boston Scientific Scimed, Inc.
Inventor： Allan C. Shuros , Joel P. Grover , Ismail Guler , Adam Grovender , Richard Charles Gunderson
CPC classification number: A61B5/02 , A61B5/0422 , A61B5/04525 , A61B5/065 , A61B5/066 , A61B5/6851 , A61B5/6853 , A61B5/686 , A61B2562/046 , A61F2/2418 , A61F2/2427
Abstract: Various techniques are described for replacement heart valve implantation. In one example, a system includes a specialized conduction system tissue activation potential sensing device, configured for delivery to an intracardiac region, a specialized conduction system tissue activation detector circuit, configured to detect, using the sensing device, a specialized conduction system tissue activation potential, and a processor circuit, configured to use information about the detected specialized conduction system tissue activation potential to generate a heart valve placement indication.
Abstract translation: 描述了替代心脏瓣膜植入的各种技术。 在一个示例中，系统包括被配置为递送到心内区域的专门的传导系统组织激活电位感测装置，被配置为使用感测装置检测特定传导系统组织激活电位的专门的传导系统组织激活检测器电路 以及处理器电路，被配置为使用关于所检测到的专用传导系统组织激活电位的信息来产生心脏瓣膜置放指示。
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公开(公告)号：US20140180152A1
公开(公告)日：2014-06-26
申请号：US14136607
申请日：2013-12-20
Applicant: Boston Scientific Scimed, Inc.
Inventor： Barun Maskara , Pramodsingh H. Thakur , Shantha Arcot-Krishnamurthy , Shibaji Shome , Sunipa Saha , Allan C. Shuros , Scott A. Meyer
CPC classification number: A61B5/0538 , A61B5/0422 , A61B5/0424 , A61B5/044 , A61B5/6858 , A61B5/6885 , A61B18/1492 , A61B2017/00044 , A61B2017/00053 , A61B2018/00267 , A61B2018/00678 , A61B2018/00839 , A61B2090/065
Abstract: A catheter system includes a mapping catheter including a plurality of mapping electrodes, each mapping electrode configured to sense signals associated with an anatomical structure. The catheter system further includes a processor operatively coupled to the plurality of mapping electrodes and configured to receive the signals sensed by the plurality of mapping electrodes, characterize the signals sensed by the plurality of mapping electrodes based on amplitudes of the sensed signals, and generate an output of a quality of contact of the plurality of mapping electrodes with the anatomical structure based on the signal characterization.
Abstract translation: 导管系统包括包括多个映射电极的映射导管，每个映射电极被配置为感测与解剖结构相关联的信号。 导管系统还包括可操作地耦合到多个映射电极并且被配置为接收由多个映射电极感测的信号的处理器，基于感测信号的幅度表征由多个映射电极感测的信号，并且生成 基于信号表征，输出多个映射电极与解剖结构的接触质量。
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Patent Agency Ranking
公开(公告)号：US20140180147A1
公开(公告)日：2014-06-26
申请号：US14136583
申请日：2013-12-20
Applicant: Boston Scientific Scimed, Inc.
Inventor： Pramodsingh H. Thakur , Barun Maskara , Allan C. Shuros , Shantha Arcot-Krishnamurthy , Shibaji Shome , Sunipa Saha
CPC classification number: A61B90/06 , A61B5/042 , A61B5/0422 , A61B18/1492 , A61B2018/00357 , A61B2018/00577 , A61B2090/061
Abstract: A catheter system includes a mapping catheter having a plurality of splines, each of the plurality of splines including a plurality of mapping electrodes. The system further includes a processor operatively coupled to the plurality of mapping electrodes and configured to receive signals sensed by the plurality of mapping electrodes. The processor is further configured to estimate an interspline distance between adjacent splines in the plurality of splines based on the signals sensed by the mapping electrodes on the adjacent splines.
Abstract translation: 导管系统包括具有多个花键的映射导管，多个花键中的每一个包括多个映射电极。 该系统还包括可操作地耦合到多个映射电极并被配置为接收由多个映射电极感测的信号的处理器。 处理器还被配置为基于由相邻样条线上的映射电极感测的信号来估计多个样条中的相邻样条之间的间距距离。
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7.发明申请SUPPRESSION OF GLOBAL ACTIVITY DURING MULTI-CHANNEL ELECTROPHYSIOLOGY MAPPING USING A WHITENING FILTER 审中-公开使用白色滤光片在多通道电生理学绘图过程中抑制全球活动公开(公告)号：US20130345583A1
公开(公告)日：2013-12-26
申请号：US13923006
申请日：2013-06-20
Applicant: Boston Scientific Scimed, Inc.
Inventor： Pramodsingh Hirasingh Thakur , Barun Maskara , Allan C. Shuros , Sunipa Saha , Shibaji Shome
IPC: A61B5/04
CPC classification number: A61B5/04017 , A61B5/0422 , A61B5/6859 , A61B5/7235 , A61B8/0883 , A61B8/5215 , A61B18/1492 , A61B2017/00053 , A61B2018/00267 , A61B2018/00839
Abstract: Electrical activity propagation along an electrode array within a cardiac chamber is reconstructed. Signals from the electrode array are sampled, and the signals are plotted in multi-dimensional space with each axis corresponding to a channel in the electrode array. A covariance matrix of the plotted signals is decomposed to characterize the spread of a data cloud of the signals in the multi-dimensional space. The data cloud is then decorrelated, such as through whitening, to suppress excursions along correlated directions (global activation) and enhance excursions along each axis (local activation).
Abstract translation: 重建沿心室内电极阵列的电活动传播。 来自电极阵列的信号被采样，并且将信号绘制在多维空间中，每个轴对应于电极阵列中的通道。 绘制的信号的协方差矩阵被分解以表征多维空间中的信号的数据云的扩展。 然后将数据云解相关，例如通过白化，以抑制沿着相关方向的偏移（全局激活）并增强沿着每个轴的偏移（局部激活）。
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8.发明申请FAR-FIELD VS LOCAL ACTIVATION DISCRIMINATION ON MULTI-ELECTRODE EGMS USING VECTOR ANALYSIS IN MULTI-DIMENSIONAL SIGNAL SPACE 有权在多维信号空间中使用矢量分析的多电极EGMS的场地与局部激活辨别公开(公告)号：US20130345537A1
公开(公告)日：2013-12-26
申请号：US13923020
申请日：2013-06-20
Applicant: Boston Scientific Scimed, Inc.
Inventor： Pramodsingh Hirasingh Thakur , Barun Maskara , Allan C. Shuros , Sunipa Saha , Shibaji Shome
CPC classification number: A61B5/0422 , A61B5/0044 , A61B5/04007 , A61B5/04012 , A61B5/0402 , A61B5/042 , A61B5/6859 , A61B18/1492
Abstract: Electrical activity propagation along an electrode array within a cardiac chamber is reconstructed. Signals are sampled from the electrode array and the signals are plotted in multi-dimensional space with each axis corresponding to a channel in the electrode array. An excursion direction of global activation in the multi-dimensional space is estimated and a change in vectors of the sampled signals over time is determined. Signals with vectors that change over time in the excursion direction are suppressed.
Abstract translation: 重建沿心室内电极阵列的电活动传播。 信号从电极阵列中采样，并且信号绘制在多维空间中，每个轴对应于电极阵列中的通道。 估计多维空间中全局激活的偏移方向，并确定采样信号随时间的向量变化。 具有沿偏移方向随时间变化的矢量的信号被抑制。
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公开(公告)号：US10827978B2
公开(公告)日：2020-11-10
申请号：US16111385
申请日：2018-08-24
Applicant: Boston Scientific Scimed Inc.
Inventor： Allan C. Shuros , Matthew S. Sulkin , Jacob I. Laughner , Vasiliy E. Buharin
Abstract: A medical system for removing far-field signals from a unipolar electrical signal is disclosed. In embodiments, the medical system comprises a catheter and a processing device communicatively coupled to the catheter. The catheter comprises a plurality of electrodes configured to sense a plurality of unipolar signals transmitted through tissue. The processing device is configured to: receive the sensed unipolar electrical signals, determine an electrode having a high level of contact with the tissue, and determine an electrode having a lower level of contact with the tissue than the electrode having the high level of contact with the tissue. Further, the processing device is configured to determine a sensed near-field electrical signal based on the unipolar electrical signal received from the electrode having the high level of contact and the unipolar electrical signal received from the electrode having the lower level of contact.
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10.发明申请公开(公告)号：US20190150842A1
公开(公告)日：2019-05-23
申请号：US16111385
申请日：2018-08-24
Applicant: Boston Scientific Scimed Inc.
Inventor： Allan C. Shuros , Matthew S. Sulkin , Jacob I. Laughner , Vasiliy E. Buharin
IPC: A61B5/00 , A61B18/14 , A61B5/0245 , A61B5/024
Abstract: A medical system for removing far-field signals from a unipolar electrical signal is disclosed. In embodiments, the medical system comprises a catheter and a processing device communicatively coupled to the catheter. The catheter comprises a plurality of electrodes configured to sense a plurality of unipolar signals transmitted through tissue. The processing device is configured to: receive the sensed unipolar electrical signals, determine an electrode having a high level of contact with the tissue, and determine an electrode having a lower level of contact with the tissue than the electrode having the high level of contact with the tissue. Further, the processing device is configured to determine a sensed near-field electrical signal based on the unipolar electrical signal received from the electrode having the high level of contact and the unipolar electrical signal received from the electrode having the lower level of contact.
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