Abstract:
Medical devices and methods for making and using the same are disclosed. An example medical device may include a medical device for renal nerve ablation. The medical device may include an elongate shaft having a distal region. An expandable member may be coupled to the distal region. A plurality of electrodes may be coupled to the expandable member and a single conductive member may be coupled to each electrode. Where one of the plurality of electrodes is active, the remaining electrodes may be inactive and act as ground or return electrodes. The electrode of the plurality of electrodes that is active may change over time.
Abstract:
The disclosure pertains to an intravascular catheter for nerve modulation, comprising an elongate member having a proximal end and a distal end, a balloon having a lumen and a balloon wall, the balloon wall comprising RF permeable sections and non-electrically conductive sections, an electrode disposed within the balloon and extending distally to the furthest distal RF permeable section. The RF permeable sections may comprise a plurality of RF permeable windows, each window having a greater circumferential dimension than an axial dimension. The intravascular system is suited for modulation of renal nerves.
Abstract:
A microparticle includes a plurality of magnetic nanoparticles having a Curie temperature between 40° and 100° C. The microparticle further includes a biocompatible polymer and/or biocompatible ceramic and a plurality of radiopaque nanoparticles.
Abstract:
Medical devices for sympathetic nerve modulation are disclosed. An example medical device for sympathetic nerve modulation may include a catheter shaft having a distal region. An expandable member may be coupled to the distal region. A flexible circuit assembly may be attached to the expandable member. The flexible circuit assembly may include a first electrode strip, a second electrode strip, and a sensor strip disposed between the first electrode strip and the second electrode strip. The first electrode strip may include a first electrode. The second electrode strip may include a second electrode. The first electrode and the second electrode may define a pair of bipolar electrodes.
Abstract:
An intravascular catheter and related methods of use or manufacture are disclosed. The catheter includes an outer tubular member having a proximal end and a distal end, and an inner tubular member having a proximal end and a distal end. An inflatable balloon have a proximal end waist coupled to the outer tubular member adjacent to the distal end thereof, and a distal end waist coupled to the inner tubular member adjacent to the distal end thereof. The balloon includes an interior surface, an exterior surface, and a lumen defined by the interior surface. The balloon further includes at least one section extending from the interior surface of the balloon to the exterior surface of the balloon. A transmitter is disposed about the inner tubular member. In addition to the above, the proximal end waist is coupled to the outer tubular member such that an inflation fluid exits the balloon.
Abstract:
Medical devices and methods for making and using the same are disclosed. An example medical device may include a medical device for tissue ablation. The medical device may include an elongated shaft having a distal region. An inflatable balloon may be mounted to the distal region. The inflatable balloon may include a body region, a proximal waist, a distal waist, a proximal cone region, and a distal cone region. A skirt may be attached to the inflatable balloon and may extend proximally from the body region. An electrode assembly may be applied directly to an outer surface of the body region of the inflatable balloon. The electrode assembly may include a first conductive member applied directly to the outer surface of the body region of the inflatable balloon and extending proximally therefrom along an outer surface of the skirt.
Abstract:
Systems for nerve and tissue modulation are disclosed. An example system may include an intravascular nerve modulation system including an elongated shaft having a proximal end region and a distal end region. The system may further include one or more ablation electrodes affixed to the distal end region of the elongated shaft. One or more ground pad electrodes may be provided and connected to a processor configured to modulate the impedance of each circuit completed between the ablation electrodes and the ground pads.
Abstract:
An intravascular catheter for tissue modulation, comprising an elongate member having a proximal end and a distal end, a balloon disposed on the elongate member and having an interior surface, an exterior surface, a lumen defined by the interior surface and at least a first region for transmitting therapeutic energy from the exterior surface of the balloon, wherein the elongate member has a fluid supply lumen having a plurality of ports fluidly connected to the balloon lumen and a fluid evacuation lumen having a port fluidly connected to the balloon lumen.
Abstract:
Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a catheter shaft having a proximal end, a distal portion, and a lumen formed therein. The distal portion may be capable of shifting between a first configuration and a second helical configuration. The distal portion may have a plurality of fluid ports formed therein. An electrode may be disposed within the lumen. The electrode may be capable of transmitting energy through the plurality of fluid ports.
Abstract:
A guide catheter may include a tubular member having an inner layer defining a lumen extending therethrough, a reinforcing braid disposed about the inner layer, a plurality of steering wires interwoven through the reinforcing braid, and an outer layer disposed about the reinforcing braid. At least a portion of the reinforcing braid may be embedded within the outer layer. An introducer sleeve may be slidably disposed over the tubular member. A flush port element may be operably connected to the introducer sleeve.