公开(公告)号：US20070129400A1

公开(公告)日：2007-06-07

申请号：US11451660

申请日：2006-06-13

Applicant: Jingwu Duan ,  Zhonghui Lu ,  David Weinstein ,  Bin Jiang

Inventor： Jingwu Duan ,  Zhonghui Lu ,  David Weinstein ,  Bin Jiang

IPC: A61K31/4709 ,  A61K31/4439 ,  A61K31/428 ,  A61K31/427 ,  A61K31/416 ,  C07D417/02 ,  C07D403/02 ,  C07D405/02 ,  C07D409/02

CPC classification number: C07D401/04 ,  C07D231/56 ,  C07D401/06 ,  C07D403/04 ,  C07D405/04 ,  C07D405/06 ,  C07D409/06 ,  C07D417/06 ,  C07D417/12

Abstract: Non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-κB activity including obesity, diabetes, inflammatory and immune diseases, and have the structure of formula (I) or an enantiomer, a diastereomer, a pharmaceutically acceptable salt, or hydrate thereof, where J is selected from NR1 or C(R4)(R4a); K is selected from NR2 or C(R5)(R5a); L is selected from NR3 or C(R6)(R6a); and A, X, Y, R1, R2, R3, R4, R4a, R5, R5a, R6, R6a, R8, R10, R11, and n are defined herein. Also provided are pharmaceutical compositions and methods of treating obesity, diabetes and inflammatory or immune associated diseases comprising said compounds.

Abstract translation: 提供非甾体化合物，其可用于治疗与糖皮质激素受体，AP-1和/或NF-κB活性（包括肥胖症，糖尿病，炎症和免疫疾病）的调节相关的疾病，并且具有式（I）的结构， 或其对映异构体，非对映异构体，药学上可接受的盐或水合物，其中J选自NR 1或C（R 4 S 4）（R 4a） / SUB>）; K选自NR 2或C（R 5）（R 5a）; L选自NR 3或C（R 6 S）（R 6a）; 和A，X，Y，R 1，R 2，R 3，R 4，R SUB R 4a，R 5，R 5a，R 6，R 6a，R SUB， R 8，R 11，R 11和n如本文所定义。 还提供了治疗肥胖症，糖尿病和包含所述化合物的炎性或免疫相关疾病的药物组合物和方法。

公开(公告)号：US09971830B2

公开(公告)日：2018-05-15

申请号：US13605999

申请日：2012-09-06

Applicant: Todd Christopher Jackson ,  William Russell Maschmeyer ,  Bin Jiang ,  Kenneth M. Lau ,  Michael Novati

Inventor： Todd Christopher Jackson ,  William Russell Maschmeyer ,  Bin Jiang ,  Kenneth M. Lau ,  Michael Novati

IPC: G06F17/30 ,  G06Q50/00

CPC classification number: G06F17/30699 ,  G06F17/30702 ,  G06F17/30867 ,  G06Q50/01

Abstract: Based on information associated with users, a social networking system recommends one or more groups for a target user to join or to create. Characteristics of the target user, characteristics of users connected to the target user, characteristics of candidate groups in the social networking system may be used to identify groups for recommendation. The social networking system may provide questions to the target user and recommend a group to the target user based on received answers to the questions. For example, the answers to the provided question identify one or more characteristics of the target user, which are used to select a group for recommendation. Additionally, the social networking system may recommend additional users for the target user to add or invite to a group based on characteristics of the target user, the additional users, and/or the group.

公开(公告)号：US08654879B2

公开(公告)日：2014-02-18

申请号：US13387308

申请日：2010-11-02

Applicant: Xiqi Gao ,  Wenjin Wang ,  Ting Li ,  Meili Zhou ,  Bin Jiang ,  Wen Zhong ,  Long Qin

Inventor： Xiqi Gao ,  Wenjin Wang ,  Ting Li ,  Meili Zhou ,  Bin Jiang ,  Wen Zhong ,  Long Qin

IPC: H04B7/02

CPC classification number: H04L25/0204 ,  H04B7/0413 ,  H04L25/0232 ,  H04L27/2647

Abstract: A multi-antenna channel estimation method based on polyphase decomposition includes: receiving frequency domain received signals transformed using discrete fourier transformation (DFT) in pilot symbols; performing phase correction on the frequency domain received signals; performing polyphase decomposition on the frequency domain received signals which are corrected using phase correction and acquiring polyphase signals; performing interpolation on the polyphase signals and acquiring the estimation values of the multi-antenna channel parameters with various linear combinations on each frequency; acquiring decorrelation array based on the pilot structure of the transmission antenna and decorrelating the estimation values of the multi-antenna channel parameters with various linear combination on each frequency using the decorrelation array and acquiring channel parameters of the pilot symbols on each frequency; acquiring channel parameters of data symbols based on the channel parameters of the pilot symbols. With the present invention, the inversion problem in multi-antenna channel estimation is avoided with lower complexity, and results of the multi-antenna channel estimation method become more accurate since the DFT and filtering are performed in the interpolation after polyphase decomposition.

Abstract translation: 基于多相分解的多天线信道估计方法包括：在导频符号中接收使用离散傅立叶变换（DFT）变换的频域接收信号; 对频域接收信号进行相位校正; 对使用相位校正和获取多相信号校正的频域接收信号执行多相分解; 对所述多相信号执行插值，并且在每个频率上以各种线性组合获取所述多天线信道参数的估计值; 基于发射天线的导频结构获取解相关阵列，并使用解相关阵列在每个频率上用各种线性组合去除多个天线信道参数的估计值，并获取每个频率上的导频符号的信道参数; 基于导频符号的信道参数获取数据符号的信道参数。 利用本发明，以更低的复杂度避免了多天线信道估计中的反转问题，并且由于在多相分解之后的内插中执行DFT和滤波，所以多天线信道估计方法的结果变得更加精确。

公开(公告)号：US20140005146A1

公开(公告)日：2014-01-02

申请号：US14005572

申请日：2012-03-16

Applicant: Stephen T. Wrobleski ,  Jagabandhu Das ,  Lidia M. Doweyko ,  Junqing Guo ,  John Hynes ,  Bin Jiang ,  James Kempson ,  Shuqun Lin ,  Steven H. Spergel ,  John S. Tokarski ,  Hong Wu ,  Bingwei Vera Yang

Inventor： Stephen T. Wrobleski ,  Jagabandhu Das ,  Lidia M. Doweyko ,  Junqing Guo ,  John Hynes ,  Bin Jiang ,  James Kempson ,  Shuqun Lin ,  Steven H. Spergel ,  John S. Tokarski ,  Hong Wu ,  Bingwei Vera Yang

IPC: C07D487/04 ,  C07F9/6561

CPC classification number: C07D487/04 ,  C07F9/6561

Abstract: Disclosed are compounds of formula (I) and pharmaceutically acceptable salts thereof. The compounds of formula (I) inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases.

Abstract translation: 公开了式（I）的化合物及其药学上可接受的盐。 式（I）化合物抑制JAK3的酪氨酸激酶活性，从而使其可用于治疗炎性和自身免疫性疾病。

公开(公告)号：US20130076130A1

公开(公告)日：2013-03-28

申请号：US13414279

申请日：2012-03-07

Applicant: Huaguang ZHANG ,  Qiuye Sun ,  Jun Yang ,  Bin Jiang ,  Lianzhi Wang ,  Dazhong Ma ,  Zhenwei Liu ,  Fei Teng ,  Zhiqiang He ,  Xintong Li

Inventor： Huaguang ZHANG ,  Qiuye Sun ,  Jun Yang ,  Bin Jiang ,  Lianzhi Wang ,  Dazhong Ma ,  Zhenwei Liu ,  Fei Teng ,  Zhiqiang He ,  Xintong Li

IPC: H02J3/00

CPC classification number: H02J3/16 ,  H02J3/1878 ,  H02P13/06 ,  Y02E40/34 ,  Y10T307/297

Abstract: Disclosed is a transformer control device and method based on a three-dimensional zone diagram policy. The method includes: setting transformers, including a transformer A and a transformer B; collecting three-phase voltage data and three-phase current data in a power system; rectifying the collected three-phase voltage data and the three-phase current data; transferring the data to the latches in a time-transfer method; transferring the data to an A/D converter of a processor to convert analog signals to digital signals; constructing a three-dimensional zone diagram in the processor; determining transformer operating conditions according to positions of points formed by voltage, reactive power factor and substation load; and adjusting the transformers. This invention adopts a simple, easy and clear three-parameter control policy including voltage, power factors and substation loads, so as to simplify analysis of transformer operating conditions, realize optimal substation operation, reduce transformer loss, and increase economic benefits.

Abstract translation: 公开了一种基于三维区域图策略的变压器控制装置和方法。 该方法包括：设置变压器，包括变压器A和变压器B; 在电力系统中收集三相电压数据和三相电流数据; 整流收集的三相电压数据和三相电流数据; 以时间传送方式将数据传送到锁存器; 将数据传送到处理器的A / D转换器，以将模拟信号转换为数字信号; 在处理器中构建三维区域图; 根据由电压，无功功率因数和变电站负载形成的点的位置确定变压器工作条件; 并调整变压器。 本发明采用简单，简单，明确的三参数控制策略，包括电压，功率因数和变电站负载，简化变压器运行状况分析，实现最佳变电站运行，减少变压器损耗，增加经济效益。

公开(公告)号：US20120182964A1

公开(公告)日：2012-07-19

申请号：US13497150

申请日：2010-11-02

Applicant: Xiqi Gao ,  Bin Jiang ,  Xiaohu You ,  Teer Ba ,  Shi Jin ,  Jue Wang ,  Dongming Wang ,  Yanxiang Jiang

Inventor： Xiqi Gao ,  Bin Jiang ,  Xiaohu You ,  Teer Ba ,  Shi Jin ,  Jue Wang ,  Dongming Wang ,  Yanxiang Jiang

IPC: H04W72/04

CPC classification number: H04B7/0697 ,  H04J11/0033 ,  H04L25/0228

Abstract: A pilot and channel estimation method for SDMA MIMO transmission downlink is provided in the present invention, and the method provides possibility for saving the orthogonal pilot resources; the pilot signals of different users in the transmitting antenna domain can occupy the same time-frequency resources, and thereby the pilot overhead of system resources can be reduced greatly; the method includes: for the MIMO transmission downlink that employs pre-coding for SDMA, taking the quantity of orthogonal pilot resources occupied by the users in the pre-coding domain as the number of data streams that can be transmitted or the number of spatial dimensions occupied first, at the transmitting end of the base station; then, performing SDMA transmission pre-coding for the orthogonal pilots in the pre-coding domain in the same way as the data signals, to obtain the pilot signals of the users in the transmitting antenna domain; wherein, the pilots of the users in the pre-coding domain can be orthogonal in the frequency domain or code domain, and the pilots of different users in the pre-coding domain can be identical or not identical to each other; the pilot signals of different users in the transmitting antenna domain can occupy the same time-frequency resources.

Abstract translation: 本发明提供了一种用于SDMA MIMO传输下行链路的导频和信道估计方法，该方法提供了保存正交试验资源的可能性; 发射天线域中不同用户的导频信号可以占用相同的时频资源，从而大大降低系统资源的导频开销; 该方法包括：对于采用SDMA预编码的MIMO传输下行链路，将预编码域中的用户占用的正交导频资源的数量作为可以发送的数据流的数量或空间维数 首先占用基站的发射端; 然后以与数据信号相同的方式对预编码域中的正交导频执行SDMA传输预编码，以获得发射天线域中用户的导频信号; 其中，预编码域中的用户的导频可以在频域或码域中正交，并且预编码域中的不同用户的导频可以相同或不相同; 发射天线域中不同用户的导频信号可以占用相同的时频资源。

公开(公告)号：US20110002952A1

公开(公告)日：2011-01-06

申请号：US12866270

申请日：2009-02-05

Applicant: Jingwu Duan ,  David S. Weinstein ,  Bin Jiang

Inventor： Jingwu Duan ,  David S. Weinstein ,  Bin Jiang

IPC: A61K31/5377 ,  C07D491/147 ,  A61K31/4375 ,  A61K38/26 ,  A61K38/28 ,  A61K39/00 ,  A61P37/00 ,  A61P29/00 ,  A61P3/00 ,  A61P37/06 ,  A61P19/02 ,  A61P25/00 ,  A61P11/06 ,  A61P1/00 ,  A61P17/06

CPC classification number: C07D491/147

Abstract: Novel non-steroidal compounds are provided which are useful in treating diseases or disorders associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-κB activity, including metabolic and inflammatory and immune diseases or disorders, having the structure of formula (I): an enantiomer, diastereomer, or tautomer thereof, or a prodrug ester thereof, or a pharmaceutically-acceptable salt thereof, in which: Z is heterocyclo or heteroaryl; -A is a 5- to 8-membered carbocyclic ring or a 5- to 8-membered heterocyclic ring; B1 and B2 rings are pyridyl rings, wherein the B1 and B2 rings are each fused to the A ring and the B1 ring is optionally substituted by one to three groups which are the same or different and are independently selected from R1, R2, and R4, and the B2 ring is optionally substituted by one to three groups which are the same or different and are independently selected from R3, R7, and R3 71, J2, and J3 are at each occurrence the same or different and are independently -AIQA2-; Q is a bond, O, S, S(0), or S(O)2; A1 and A2 are the same or different and are at each occurrence independently selected from a bond, C1-3 alkylene, substituted C1-3 alkylene, C24 alkenylene, and substituted C24 alkenylene, provided that A1 and A2 are chosen so that ring A is a 5- to 8-membered carbocyclic or heterocyclic ring; R1 to R11 are as defined herein.

Abstract translation: 提供新的非甾体化合物，其可用于治疗与调节糖皮质激素受体，AP-1和/或NF-κB活性相关的疾病或病症，包括具有结构的代谢和炎症和免疫疾病或病症 式（I）的化合物：其对映异构体，非对映异构体或其互变异构体或其前药酯或其药学上可接受的盐，其中：Z是杂环基或杂芳基; -A是5-至8-元碳环或5-至8-元杂环; B1和B2环是吡啶环，其中B1和B2环各自与A环稠合，B1环任选被一至三个相同或不同并且独立地选自R 1，R 2和R 4的基团取代 并且B2环任选地被一至三个相同或不同并且独立地选自R3，R7和R371的基团取代，J2和J3在每次出现时相同或不同，并且独立地为-AIQA2- ; Q是键，O，S，S（0）或S（O）2; A1和A2相同或不同，并且在每次出现时独立地选自键，C1-3亚烷基，取代的C1-3亚烷基，C24亚烯基和取代的C24亚烯基，条件是选择A1和A2，使得环A为 5-至8-元碳环或杂环; R1至R11如本文所定义。

公开(公告)号：USD614169S1

公开(公告)日：2010-04-20

申请号：US29336888

申请日：2009-05-11

Applicant: Bin Jiang ,  Man-Zhong Wang ,  Ju-Lan Hao ,  Shi-Pei Zhang

Designer： Bin Jiang ,  Man-Zhong Wang ,  Ju-Lan Hao ,  Shi-Pei Zhang

公开(公告)号：USD607435S1

公开(公告)日：2010-01-05

申请号：US29334661

申请日：2009-03-31

Applicant: Bin Jiang

Designer： Bin Jiang

公开(公告)号：US20090190619A1

公开(公告)日：2009-07-30

申请号：US12363103

申请日：2009-01-30

Applicant: Haihua Qi ,  Bifeng Xiong ,  Bin Jiang ,  Hong Ma

Inventor： Haihua Qi ,  Bifeng Xiong ,  Bin Jiang ,  Hong Ma

IPC: H01S5/024

CPC classification number: H01S5/4025 ,  H01S5/02272 ,  H01S5/024 ,  H01S5/4018

Abstract: The present invention provides a semiconductor laser package including a heat sink, a laser bar with a plurality of lasers on the heat sink, an insulated layer arranged between said heat sink and said laser bar, a solder layer combining said insulated layer with said laser bar, and a clearance crossing said solder layer defined between adjacent lasers.

Abstract translation: 本发明提供了一种半导体激光器封装，其包括散热器，在散热器上具有多个激光器的激光棒，布置在所述散热器和所述激光棒之间的绝缘层，将所述绝缘层与所述激光棒 以及在相邻激光器之间限定的焊料层的间隙。