公开(公告)号：US20240164668A1

公开(公告)日：2024-05-23

申请号：US18520380

申请日：2023-11-27

Applicant: Cercacor Laboratories, Inc.

Inventor： Kevin Pauley ,  Cristiano Dalvi ,  Hung Vo ,  Jesse Chen ,  Ferdyan Lesmana ,  Jeroen Poeze ,  Sean Merritt

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/145 ,  G01J1/16 ,  G01N21/31 ,  G01N21/47 ,  G01N21/49 ,  G01N21/59

CPC classification number: A61B5/14552 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/4875 ,  G01J1/1626 ,  G01N21/31 ,  G01N21/4738 ,  G01N21/49 ,  G01N21/59 ,  A61B2562/0238 ,  G01J2001/1636 ,  G01J2001/1652 ,  G01N2021/3181

Abstract: An optical measurement device includes a light source, a first detector, and a second detector. The light source emits light to a measurement site of a patient and one or more detectors detect the light from the light source. At least a portion of a detector is translucent and the light passes through the translucent portion prior to reaching the measurement site. A detector receives the light after attenuation and/or reflection or refraction by the measurement site. A processor determines a light intensity of the light source, a light intensity through a tissue site, or a light intensity of reflected or refracted light based on light detected by the one or more detectors. The processor can estimate a concentration of an analyte at the measurement site or an absorption or reflection at the measurement site.

公开(公告)号：US11864890B2

公开(公告)日：2024-01-09

申请号：US16985497

申请日：2020-08-05

Applicant: Cercacor Laboratories, Inc.

Inventor： Kevin Pauley ,  Cristiano Dalvi ,  Hung Vo ,  Jesse Chen ,  Ferdyan Lesmana ,  Jeroen Poeze ,  Sean Merritt

IPC: A61B5/1455 ,  A61B5/145 ,  G01J1/16 ,  G01N21/47 ,  G01N21/31 ,  G01N21/49 ,  A61B5/00 ,  G01N21/59

CPC classification number: A61B5/14552 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/4875 ,  G01J1/1626 ,  G01N21/31 ,  G01N21/4738 ,  G01N21/49 ,  G01N21/59 ,  A61B2562/0238 ,  G01J2001/1636 ,  G01J2001/1652 ,  G01N2021/3181

Abstract: An optical measurement device includes a light source, a first detector, and a second detector. The light source emits light to a measurement site of a patient and one or more detectors detect the light from the light source. At least a portion of a detector is translucent and the light passes through the translucent portion prior to reaching the measurement site. A detector receives the light after attenuation and/or reflection or refraction by the measurement site. A processor determines a light intensity of the light source, a light intensity through a tissue site, or a light intensity of reflected or refracted light based on light detected by the one or more detectors. The processor can estimate a concentration of an analyte at the measurement site or an absorption or reflection at the measurement site.

公开(公告)号：US11832940B2

公开(公告)日：2023-12-05

申请号：US17004663

申请日：2020-08-27

Applicant: Cercacor Laboratories, Inc.

Inventor： Mohamed K. Diab ,  Kevin Hughes Pauley ,  Jesse Chen ,  Cristiano Dalvi ,  Hung The Vo ,  Ferdyan Lesmana ,  Jeroen Poeze ,  Ruiqi Long ,  Venkatramanan Krishnamani ,  Frank Lee

IPC: A61B5/145 ,  G02B27/30 ,  A61B5/1455 ,  A61B5/00

CPC classification number: A61B5/14532 ,  A61B5/1455 ,  A61B5/6826 ,  G02B27/30

Abstract: Systems, methods, and apparatuses for enabling a plurality of non-invasive, physiological sensors to obtain physiological measurements from essentially the same, overlapping, or proximate regions of tissue of a patient are disclosed. Each of a plurality of sensors can be integrated with or attached to a multi-sensor apparatus and can be oriented such that each sensor is directed towards, or can obtain a measurement from, the same or a similar location.

公开(公告)号：US20210113121A1

公开(公告)日：2021-04-22

申请号：US17004663

申请日：2020-08-27

Applicant: Cercacor Laboratories, Inc.

Inventor： Mohamed K. Diab ,  Kevin Hughes Pauley ,  Jesse Chen ,  Cristiano Dalvi ,  Hung The Vo ,  Ferdyan Lesmana ,  Jeroen Poeze ,  Ruiqi Long ,  Venkatramanan Krishnamani ,  Frank Lee ,  Mathew Paul

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1455 ,  G02B27/30

Abstract: Systems, methods, and apparatuses for enabling a plurality of non-invasive, physiological sensors to obtain physiological measurements from essentially the same, overlapping, or proximate regions of tissue of a patient are disclosed. Each of a plurality of sensors can be integrated with or attached to a multi-sensor apparatus and can be oriented such that each sensor is directed towards, or can obtain a measurement from, the same or a similar location.

公开(公告)号：US10750984B2

公开(公告)日：2020-08-25

申请号：US15850755

申请日：2017-12-21

Applicant: Cercacor Laboratories, Inc.

Inventor： Kevin Pauley ,  Cristiano Dalvi ,  Hung Vo ,  Jesse Chen ,  Ferdyan Lesmana ,  Jeroen Poeze ,  Sean Merritt

IPC: A61B5/1455 ,  A61B5/145 ,  G01J1/16 ,  G01N21/47 ,  G01N21/31 ,  G01N21/49 ,  A61B5/00 ,  G01N21/59

Abstract: An optical measurement device includes a light source, a first detector, and a second detector. The light source emits light to a measurement site of a patient and one or more detectors detect the light from the light source. At least a portion of a detector is translucent and the light passes through the translucent portion prior to reaching the measurement site. A detector receives the light after attenuation and/or reflection or refraction by the measurement site. A processor determines a light intensity of the light source, a light intensity through a tissue site, or a light intensity of reflected or refracted light based on light detected by the one or more detectors. The processor can estimate a concentration of an analyte at the measurement site or an absorption or reflection at the measurement site.

公开(公告)号：US20190142283A1

公开(公告)日：2019-05-16

申请号：US16230734

申请日：2018-12-21

Applicant: Cercacor Laboratories, Inc.

Inventor： Marcelo M. Lamego ,  Massi Joe E. Kiani ,  Jeroen Poeze ,  Cristiano Dalvi ,  Sean Merritt ,  Hung Vo ,  Gregory A. Olsen ,  Ferdyan Lesmana

IPC: A61B5/0205 ,  A61B5/00 ,  A61B5/1455 ,  A61B5/145 ,  A61B5/1459

CPC classification number: A61B5/0205 ,  A61B5/0022 ,  A61B5/021 ,  A61B5/0816 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1459 ,  A61B5/7435 ,  A61B5/7475 ,  A61B2560/0223 ,  A61B2560/0431

Abstract: The present disclosure includes a handheld processing device including medical applications for minimally and noninvasive glucose measurements. In an embodiment, the device creates a patient specific calibration using a measurement protocol of minimally invasive measurements and noninvasive measurements, eventually creating a patient specific noninvasive glucometer. Additionally, embodiments of the present disclosure provide for the processing device to execute medical applications and non-medical applications.

公开(公告)号：US10159412B2

公开(公告)日：2018-12-25

申请号：US14703816

申请日：2015-05-04

Applicant: Cercacor Laboratories, Inc.

Inventor： Marcelo M. Lamego ,  Massi Joe E. Kiani ,  Jeroen Poeze ,  Cristiano Dalvi ,  Sean Merritt ,  Hung Vo ,  Gregory A. Olsen ,  Ferdyan Lesmana

IPC: A61B5/1455 ,  A61B5/0205 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1459 ,  A61B5/021 ,  A61B5/08

Abstract: The present disclosure includes a handheld processing device including medical applications for minimally and noninvasive glucose measurements. In an embodiment, the device creates a patient specific calibration using a measurement protocol of minimally invasive measurements and noninvasive measurements, eventually creating a patient specific noninvasive glucometer. Additionally, embodiments of the present disclosure provide for the processing device to execute medical applications and non-medical applications.

公开(公告)号：US20180199871A1

公开(公告)日：2018-07-19

申请号：US15850755

申请日：2017-12-21

Applicant: Cercacor Laboratories, Inc.

Inventor： Kevin Pauley ,  Cristiano Dalvi ,  Hung Vo ,  Jesse Chen ,  Ferdyan Lesmana ,  Jeroen Poeze ,  Sean Merritt

IPC: A61B5/1455 ,  A61B5/145 ,  A61B5/00 ,  G01N21/59

CPC classification number: A61B5/14552 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/4875 ,  A61B2562/0238 ,  G01J1/1626 ,  G01J2001/1636 ,  G01J2001/1652 ,  G01N21/31 ,  G01N21/4738 ,  G01N21/49 ,  G01N21/59 ,  G01N2021/3181

Abstract: An optical measurement device includes a light source, a first detector, and a second detector. The light source emits light to a measurement site of a patient and one or more detectors detect the light from the light source. At least a portion of a detector is translucent and the light passes through the translucent portion prior to reaching the measurement site. A detector receives the light after attenuation and/or reflection or refraction by the measurement site. A processor determines a light intensity of the light source, a light intensity through a tissue site, or a light intensity of reflected or refracted light based on light detected by the one or more detectors. The processor can estimate a concentration of an analyte at the measurement site or an absorption or reflection at the measurement site.

公开(公告)号：US09591975B2

公开(公告)日：2017-03-14

申请号：US13888266

申请日：2013-05-06

Applicant: CERCACOR LABORATORIES, INC.

Inventor： Cristiano Dalvi ,  Marcelo Lamego ,  Sean Merritt ,  Hung Vo ,  Johannes Bruinsma ,  Jeroen Poeze ,  Ferdyan Lesmana ,  Greg Olsen ,  Massi Joe E. Kiani

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/024 ,  A61B5/145

CPC classification number: A61B5/02427 ,  A61B5/02416 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/4875 ,  A61B5/6816 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/6838 ,  A61B5/6843 ,  A61B5/70 ,  A61B5/7275 ,  A61B2562/146

Abstract: A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector.

Abstract translation: 用于测量医疗患者的一个或多个生理参数的无创生理传感器可以包括插入在光源和光电检测器之间的凸块。 凸起可以放置成与患者的身体组织接触，从而减少身体组织的厚度。 结果，可以减少光源和光电检测器之间的光程。 此外，传感器可以包括可将热量远离光源引导的散热器。 此外，传感器可以包括在光源和光电检测器之间的光路中的屏蔽。 屏蔽可以降低由光电检测器接收的噪声。

公开(公告)号：US20140155712A1

公开(公告)日：2014-06-05

申请号：US14153895

申请日：2014-01-13

Applicant: CERCACOR LABORATORIES, INC.

Inventor： Marcelo M. Lamego ,  Sean Merritt ,  Cristiano Dalvi ,  Hung Vo ,  Johannes Bruinsma ,  Jeroen Poeze ,  Ferdyan Lesmana ,  Massi Joe E. Kiani

IPC: A61B5/1455

CPC classification number: A61B5/1455 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14552 ,  A61B5/6816 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/6838 ,  A61B5/6843 ,  A61B2562/0233 ,  A61B2562/04 ,  A61B2562/046 ,  A61B2562/146

Abstract: The present disclosure relates to an interface for a noninvasive glucose sensor that comprises a front-end adapted to receive an input signals from optical detectors and provide corresponding digital signals. In one embodiment, the front-end comprises switched capacitor circuits that are capable of handling multiple streams signals from the optical detectors. In another embodiment, the front-end comprises transimpedance amplifiers that are capable of handling multiple streams of input signals. In this embodiment, the transimpedance amplifier may be configured based on its own characteristics, such as its impedance, the impedance of the photodiodes to which it is coupled, and the number of photodiodes to which it is coupled.

Abstract translation: 本公开涉及一种用于非侵入式葡萄糖传感器的接口，其包括适于接收来自光学检测器的输入信号并提供相应数字信号的前端。 在一个实施例中，前端包括能够处理来自光学检测器的多个流信号的开关电容器电路。 在另一个实施例中，前端包括能够处理多个输入信号流的跨阻放大器。 在该实施例中，跨阻抗放大器可以基于其自身的特性，例如其阻抗，与其耦合的光电二极管的阻抗以及与其耦合的光电二极管的数量来配置。