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公开(公告)号：US07344533B2
公开(公告)日：2008-03-18
申请号：US10260187
申请日：2002-09-28
申请人： Robert M. Pearson , Steven A. Daniel , Daniel J. Balbierz , Theodore C. Johnson , Zia Yassinzadeh
发明人： Robert M. Pearson , Steven A. Daniel , Daniel J. Balbierz , Theodore C. Johnson , Zia Yassinzadeh
IPC分类号： A61B18/18
CPC分类号： A61B18/1477 , A61B2018/00011 , A61B2018/00083 , A61B2018/00196 , A61B2018/00577 , A61B2018/00702 , A61B2018/00726 , A61B2018/00738 , A61B2018/00744 , A61B2018/0075 , A61B2018/00755 , A61B2018/00761 , A61B2018/00791 , A61B2018/00869 , A61B2018/00875 , A61B2018/124 , A61B2018/1253 , A61B2018/1425 , A61B2018/143 , A61B2018/1432 , A61B2218/002
摘要： A method and apparatus for carrying our thermal ablation of target tissue is disclosed. The apparatus includes an RF ablation device having a multi-electrode electrode assembly designed to be deployed in target tissue, defining a selected-volume tissue region to be ablated, and having infusion channels for infusing a liquid into the target tissue during the ablation process. A control unit in the apparatus is operably connected to an RF energy source, for controlling the RF power level supplied to the electrodes, and to an infusion device, for controlling the rate of infusion of a liquid through the device into the tissue. During both electrode deployment and tissue ablation, impedance and or temperature measurements made within the tissue are used to control the RF source and infusion device, for optimizing the time and extent of tissue ablation.
摘要翻译： 公开了一种用于携带我们的靶组织热消融的方法和装置。 该装置包括RF消融装置，其具有设计成部署在靶组织中的多电极电极组件，限定要消融的选择体积的组织区域，并且具有用于在消融过程期间将液体注入靶组织的输注通道。 装置中的控制单元可操作地连接到RF能量源，用于控制提供给电极的RF功率水平，以及用于控制通过装置将液体输入到组织中的输注装置。 在电极部署和组织消融期间，组织内进行的阻抗和/或温度测量用于控制RF源和输注装置，以优化组织消融的时间和程度。
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公开(公告)号：US07108696B2
公开(公告)日：2006-09-19
申请号：US10668433
申请日：2003-09-22
申请人： Steven A. Daniel , Daniel J. Balbierz , Robert D. Russell , Robert Pearson , Andres Tamayo , Takehito Jimbo , Karen Frischmeyer
发明人： Steven A. Daniel , Daniel J. Balbierz , Robert D. Russell , Robert Pearson , Andres Tamayo , Takehito Jimbo , Karen Frischmeyer
CPC分类号： A61B18/1477 , A61B2017/003 , A61B2018/00029 , A61B2018/00083 , A61B2018/00142 , A61B2018/00654 , A61B2018/00755 , A61B2018/00797 , A61B2018/00875 , A61B2018/1435 , A61B2090/3925 , A61B2218/002 , A61M5/142 , G06F19/00
摘要： Ablation devices and associated methods are provided for use in palliative treatment of a bone tumor on or in a compact bone region. The bone treatment devices include an elongate probe having a distal end. A proximal end of the probe supports placement in a location at or adjacent to the bone tumor. Electrodes are carried within the probe for deployment from the distal end into the bone tumor. The electrodes may be shapable to create, upon deployment, an array of electrodes that defines a geometric area within the bone tumor. Application of energy, for example energy from a radio frequency (RF) source, to the area of the bone tumor via the electrodes destroys at least a portion of the nerve receptors located in or adjacent to the tumor and produces a reduction in pain associated with the bone tumor. Liquid, such as a polymer in liquid form, may be injected through an electrode needle, with electrode heating being employed to allow introduction of the polymer solution through the needle and/or hardening at the site of injection.
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公开(公告)号：US06770070B1
公开(公告)日：2004-08-03
申请号：US09527906
申请日：2000-03-17
申请人： Daniel J. Balbierz
发明人： Daniel J. Balbierz
IPC分类号： A61B1818
CPC分类号： A61B10/04 , A61B8/06 , A61B8/12 , A61B10/02 , A61B10/0233 , A61B17/00491 , A61B18/1477 , A61B18/1482 , A61B18/1487 , A61B18/1492 , A61B2017/00495 , A61B2018/00029 , A61B2018/00541 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00875 , A61B2018/1425 , A61B2018/1472 , A61B2018/183 , A61B2218/002 , A61B2218/007
摘要： A method and apparatus for obtaining a lung biopsy with an apparatus capable of sealing tears within the lung and pleural space to reduce the risk of pneumothorax or pulmonary hemorrhage. The apparatus includes an RF ablation apparatus having a lung biopsy device an energy delivery device including at least one electrode designed to be deployed into target lung tissue, and a sensor. A closure device is operatively coupled to the elongated member to produce an immediate tight seal and promote healing at the tissue interface. A feedback control device is operatively coupled to the sensor and a RF source for controlling energy delivered to the electrodes.
摘要翻译： 一种用于能够密封肺和胸膜空间内的泪液以减少气胸或肺出血风险的装置来获得肺活检的方法和装置。 该装置包括具有肺活检装置的RF消融装置，能量递送装置包括设计成部署到目标肺组织中的至少一个电极和传感器。 闭合装置可操作地联接到细长构件以产生立即紧密密封并促进组织界面处的愈合。 反馈控制装置可操作地耦合到传感器和RF源，用于控制传送到电极的能量。
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公开(公告)号：US06770038B2
公开(公告)日：2004-08-03
申请号：US09495619
申请日：2000-02-01
申请人： Daniel J. Balbierz , Robert Bley
发明人： Daniel J. Balbierz , Robert Bley
IPC分类号： A61B500
CPC分类号： A61M25/0102 , A61M25/00 , A61M25/0043 , A61M25/0612
摘要： The present invention relates to a stiffening member, which is a stylet, that helps increase the fluid flow area within a catheter. In a preferred embodiment, the stylet is made of a single piece of flat rectangular stock that can be twisted to provide equal rigidity in all directions. A cross-section of the stylet reveals that the substantially flat rectangular shape of the stylet permits maximum fluid flow between the stylet and the catheter. This results in increased ease in manipulating and removing the stylet from the catheter. In addition, because the preferred embodiment of the stylet comprises a single element, it is easier to manufacture and should result in lower manufacturing costs. Moreover, the use of the present invention should also result in lower overall health-care costs.
摘要翻译： 本发明涉及一种加强构件，其是探针，其有助于增加导管内的流体流动面积。 在优选实施例中，探针由单片扁平矩形坯料制成，其可以被扭转以在所有方向上提供相等的刚度。 探针的横截面显示管心针的基本平坦的矩形形状允许探针和导管之间的最大流体流动。 这导致更容易地从导管操作和去除探针。 此外，由于探针的优选实施例包括单个元件，因此制造更容易并且应导致较低的制造成本。 而且，本发明的使用也应降低整体医疗成本。
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公开(公告)号：US06622731B2
公开(公告)日：2003-09-23
申请号：US10044081
申请日：2002-01-11
申请人： Steven A. Daniel , Daniel J. Balbierz , Robert D. Russell , Robert Pearson , Andres Tamayo , Takehito Jimbo , Karen Frischmeyer
发明人： Steven A. Daniel , Daniel J. Balbierz , Robert D. Russell , Robert Pearson , Andres Tamayo , Takehito Jimbo , Karen Frischmeyer
IPC分类号： A61B1900
CPC分类号： A61B18/1477 , A61B2017/003 , A61B2018/00029 , A61B2018/00083 , A61B2018/00142 , A61B2018/00654 , A61B2018/00755 , A61B2018/00797 , A61B2018/00875 , A61B2018/1435 , A61B2090/3925 , A61B2218/002 , A61M5/142 , G06F19/00
摘要： Ablation devices and associated methods are provided for use in palliative treatment of a bone tumor on or in a compact bone region. The bone treatment devices include an elongate probe having a distal end. A proximal end of the probe supports placement in a location at or adjacent to the bone tumor. Electrodes are carried within the probe for deployment from the distal end into the bone tumor. The electrodes may be shapable to create, upon deployment, an array of electrodes that defines a geometric area within the bone tumor. Application of energy, for example energy from a radio frequency (RF) source, to the area of the bone tumor via the electrodes destroys at least a portion of the nerve receptors located in or adjacent to the tumor and produces a reduction in pain associated with the bone tumor. Liquid, such as a polymer in liquid form, may be injected through an electrode needle, with electrode heating being employed to allow introduction of the polymer solution through the needle and/or hardening at the site of injection.
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26.发明授权公开(公告)号：US08747421B2
公开(公告)日：2014-06-10
申请号：US13089216
申请日：2011-04-18
IPC分类号： A61B17/068
CPC分类号： A61B17/068 , A61B17/072 , A61B17/07207 , A61B17/115 , A61B2017/07214 , A61B2017/07228 , A61B2017/07271 , A61F5/0086
摘要： A staple housing includes an array of staples each in a staple delivery position or “ready position” ready to be fired into target tissue. A staple driver is advanceable to drive the ready-position staples from the staple head into the tissue using staple pushers. During use, the staples in the ready positions are simultaneously fired into the target tissue using the staple pushers, forming an array of staples in the target tissue. After the array has been fired, one or more feed mechanisms within the staple housing advance a second group of staples from one or more staple storage locations into the ready positions in preparation for firing of the second group of staples.
摘要翻译： 订书钉壳体包括各自位于钉送出位置的订书钉阵列或准备好被烧制到目标组织中的“就绪位置”。 订书钉驱动器可前进，以使用订书钉推动器将订书钉从订书钉驱动到组织中。 在使用期间，准备位置中的订书钉使用订书钉推动器同时被烧制到目标组织中，从而在目标组织中形成一排钉。 在阵列被点火之后，钉仓壳体内的一个或多个进给机构将第二组订书钉从一个或多个订书钉存储位置推进到就绪位置，以准备第二组钉的点火。
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公开(公告)号：US08540710B2
公开(公告)日：2013-09-24
申请号：US13609369
申请日：2012-09-11
IPC分类号： A61B18/14
CPC分类号： A61B18/18 , A61B18/1477 , A61B2018/00011 , A61B2018/00083 , A61B2018/00196 , A61B2018/00577 , A61B2018/00642 , A61B2018/00654 , A61B2018/00875 , A61B2018/124 , A61B2018/1273 , A61B2018/128 , A61B2018/1497 , A61B2218/002
摘要： Disclosed in the present application are devices for localized delivery of energy and methods of using such devices, particularly for therapeutic treatment of biological tissues. The disclosed methods may involve positioning and deploying the energy delivery members in a target site, and delivering energy through the energy delivery members. The disclosed devices may also be used to create a tissue tract within a biological tissue and to ablate the tissue tract.
摘要翻译： 在本申请中公开的是用于局部递送能量的装置和使用这种装置的方法，特别是用于生物组织的治疗性治疗。 所公开的方法可以涉及将能量递送构件定位和部署在目标地点中，并且通过能量递送构件传递能量。 所公开的装置还可用于在生物组织内产生组织道并消融组织道。
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28.发明申请公开(公告)号：US20110192881A1
公开(公告)日：2011-08-11
申请号：US13089216
申请日：2011-04-18
IPC分类号： A61B17/068 , A61B17/072
CPC分类号： A61B17/068 , A61B17/072 , A61B17/07207 , A61B17/115 , A61B2017/07214 , A61B2017/07228 , A61B2017/07271 , A61F5/0086
摘要： A staple housing includes an array of staples each in a staple delivery position or “ready position” ready to be fired into target tissue. A staple driver is advanceable to drive the ready-position staples from the staple head into the tissue using staple pushers. During use, the staples in the ready positions are simultaneously fired into the target tissue using the staple pushers, forming an array of staples in the target tissue. After the array has been fired, one or more feed mechanisms within the staple housing advance a second group of staples from one or more staple storage locations into the ready positions in preparation for firing of the second group of staples.
摘要翻译： 订书钉壳体包括各自位于钉送出位置的订书钉阵列或准备好被烧制到目标组织中的“就绪位置”。 订书钉驱动器可前进，以使用订书钉推动器将订书钉从订书钉驱动到组织中。 在使用期间，准备位置中的订书钉使用订书钉推动器同时被烧制到目标组织中，从而在目标组织中形成一排钉。 在阵列被点火之后，钉仓壳体内的一个或多个进给机构将第二组订书钉从一个或多个订书钉存储位置推进到就绪位置，以准备第二组钉的点火。
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公开(公告)号：US20090076497A1
公开(公告)日：2009-03-19
申请号：US11893911
申请日：2007-08-17
IPC分类号： A61B18/14
CPC分类号： A61M25/1002 , A61B18/1477 , A61B2018/00011 , A61B2018/00017 , A61B2018/00029 , A61B2018/00291 , A61B2018/143 , A61B2018/1475 , A61M2025/0085
摘要： A method of controlling ablation volume depth includes providing a treatment apparatus. The apparatus comprises a housing having a proximal and distal end including a tissue contacting surface. The housing defines an interior with an energy delivery device positionable in the interior. The energy delivery device includes at least one electrode with a tissue penetrating distal end and is configured to be advanced from the interior into a target tissue site to define an ablation volume. An advancement device is coupled to the energy delivery device and is configured to advance the at least one electrode. The at least one electrode is advanced to a selected deployment depth beneath a tissue surface while avoiding a critical structure. Energy is delivered from the energy delivery device. An ablation volume is created at a controlled depth below the tissue surface responsive to the deployment depth while minimizing injury to the critical structure.
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公开(公告)号：US06869430B2
公开(公告)日：2005-03-22
申请号：US09823903
申请日：2001-03-30
IPC分类号： A61B10/00 , A61B1/00 , A61B10/02 , A61B17/00 , A61B17/22 , A61B17/34 , A61B18/00 , A61B18/12 , A61B18/14 , A61B19/00 , A61B18/18
CPC分类号： A61B18/1206 , A61B5/0071 , A61B10/02 , A61B10/0283 , A61B18/00 , A61B18/1477 , A61B18/1482 , A61B18/1815 , A61B90/39 , A61B2017/00022 , A61B2017/00061 , A61B2017/003 , A61B2017/00849 , A61B2017/00867 , A61B2017/22082 , A61B2018/00029 , A61B2018/00083 , A61B2018/00142 , A61B2018/00577 , A61B2018/00642 , A61B2018/00654 , A61B2018/0069 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/124 , A61B2018/143 , A61B2018/1432 , A61B2018/1472 , A61B2018/1861 , A61B2090/064 , A61B2090/3782 , A61B2090/3941 , A61B2090/3966 , A61B2218/002 , A61N7/02 , C08L2201/12
摘要： An embodiment of the invention provides a tissue biopsy and treatment apparatus that comprises an elongated delivery device that is positionable in tissue and includes a lumen. A sensor array having a plurality of resilient members is deployable from the elongated delivery device. At least one of the plurality of resilient members is positionable in the elongated delivery device in a compacted state and deployable with curvature into tissue from the elongated delivery device in a deployed state. At least one of the plurality of resilient members includes at least one of a sensor, a tissue piercing distal end or a lumen. The sensor array has a geometric configuration adapted to volumetrically sample tissue at a tissue site to differentiate or identify tissue at the target tissue site. At least one energy delivery device is coupled to one of the sensor array, at least one of the plurality of resilient members or the elongated delivery device.
摘要翻译： 本发明的一个实施例提供一种组织活检和治疗装置，其包括可定位在组织中并包括内腔的细长递送装置。 具有多个弹性构件的传感器阵列可从细长的输送装置展开。 多个弹性构件中的至少一个可以处于压实状态的细长递送装置中定位，并且在展开状态下可从细长的递送装置以曲率展开到组织中。 多个弹性构件中的至少一个包括传感器，组织穿孔远端或管腔中的至少一个。 传感器阵列具有适于在组织部位体积地采样组织以区分或识别靶组织部位的组织的几何构型。 至少一个能量输送装置耦合到传感器阵列中的一个，多个弹性构件或细长输送装置中的至少一个。
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