Method of delivering cell therapy to a target site
    21.
    发明授权
    Method of delivering cell therapy to a target site 有权
    将细胞治疗递送到目标部位的方法

    公开(公告)号:US08784800B2

    公开(公告)日:2014-07-22

    申请号:US12400059

    申请日:2009-03-09

    摘要: A method of delivering therapy to a target site. The method includes (a) obtaining a base image of the target site, (b) injecting a dose of a mix of a therapeutic agent and a contrast agent into a first injection location at the target site via a needle passing through a catheter, (c) collecting sequential fluoroscopic images of a contrast agent dispersion cloud at the first injection location, (d) determining a contrast agent dispersion area from the sequential fluoroscopic images, (e) determining a therapeutic agent dispersion area from the contrast agent dispersion area, (f) marking the therapeutic agent dispersion area on the base image of the target site, and (g) repeating (b) through (f) until the target site is substantially covered with overlapping therapeutic agent dispersion areas corresponding to a plurality of injections at a plurality of injection locations at the target site.

    摘要翻译: 将治疗递送到目标部位的方法。 该方法包括(a)获得目标部位的基础图像,(b)通过穿过导管的针将目标部位的剂量的治疗剂和造影剂的剂量注射到目标部位的第一注射位置( c)在第一注射位置处收集造影剂分散云的顺序透视图像,(d)从顺序透视图像确定造影剂分散区域,(e)从造影剂分散区域确定治疗剂分散区域( f)在目标部位的基础图像上标记治疗剂分散区域,和(g)重复(b)到(f)直到目标部位基本上覆盖有与多个注射相对应的重叠治疗剂分散区域 在目标地点的多个注射位置。

    NAVIGATION ENABLED LEAD DELIVERY CATHETER
    23.
    发明申请
    NAVIGATION ENABLED LEAD DELIVERY CATHETER 审中-公开
    导航启用导线导管

    公开(公告)号:US20100185083A1

    公开(公告)日:2010-07-22

    申请号:US12643737

    申请日:2009-12-21

    IPC分类号: A61B5/05 A61B19/00

    摘要: A catheter system for positioning of a medical instrument includes a first elongate member having a first lumen. The system also includes a second elongate member that includes a second lumen that receives the medical instrument. The second elongate member is coupled directly to the first elongate member, and the second elongate member is cuttable to allow removal of the medical instrument from the second lumen. The second elongate member is also selectively collapsible and expandable to change a size of the second lumen. Furthermore, the system includes a navigation tool operable for allowing detection of a location of the catheter system. The navigation tool is received in the first lumen, and the second elongate member is cuttable without cutting the first elongate member and the navigation tool.

    摘要翻译: 用于定位医疗器械的导管系统包括具有第一腔的第一细长构件。 该系统还包括第二细长构件,其包括接纳医疗器械的第二腔。 第二细长构件直接连接到第一细长构件,并且第二细长构件是可切割的,以允许将医疗器械从第二腔排出。 第二细长构件也可选择性地可折叠并可膨胀以改变第二内腔的尺寸。 此外,该系统包括可操作以允许检测导管系统的位置的导航工具。 导航工具被容纳在第一内腔中,并且第二细长构件是可切割的,而不切割第一细长构件和导航工具。

    CATHETER SYSTEM WITH REINFORCED MEMBER
    24.
    发明申请
    CATHETER SYSTEM WITH REINFORCED MEMBER 审中-公开
    带加强构件的导管系统

    公开(公告)号:US20100082000A1

    公开(公告)日:2010-04-01

    申请号:US12241741

    申请日:2008-09-30

    IPC分类号: A61M25/14 A61M25/00

    摘要: A catheter system for positioning of a medical instrument within a body. The catheter system includes a hub defining a main lumen therethrough for passage of the medical instrument. The catheter system also includes an elongate tubular member defining a lumen therethrough. The lumen of the elongate tubular member is in communication with the main lumen of the hub for further passage of the medical instrument. The elongate tubular member defines a first portion and a second portion. The catheter system also includes a reinforcement member that is fixedly coupled to and reinforces the elongate tubular member, the reinforcement member includes a first part, a second part, and a partition defined between the first and second parts. The first and second parts are adapted to selectively move away from each other along the partition to thereby move the first and second portions away from each other and to uncover the medical instrument.

    摘要翻译: 一种用于将医疗器械定位在体内的导管系统。 导管系统包括限定通过其的主腔的轮毂,用于医疗器械的通过。 导管系统还包括限定通过其中的腔的细长管状构件。 细长管状构件的内腔与毂的主腔连通,以进一步通过医疗器械。 细长管状构件限定第一部分和第二部分。 导管系统还包括固定地联接到细长管状构件并加强细长管状构件的加强构件,加强构件包括第一部分,第二部分和限定在第一和第二部分之间的隔板。 第一和第二部分适于选择性地沿着隔板彼此远离地移动,从而使第一和第二部分彼此远离并且揭开医疗器械。

    Display of an Acquired Cine Loop for Procedure Navigation
    25.
    发明申请
    Display of an Acquired Cine Loop for Procedure Navigation 有权
    显示用于程序导航的获取电路循环

    公开(公告)号:US20120201432A1

    公开(公告)日:2012-08-09

    申请号:US13020543

    申请日:2011-02-03

    IPC分类号: G06K9/78

    摘要: The present disclosure relates to acquiring image data of a subject and selecting image data to be displayed. The image data can include a plurality of frames that relate to a specific location of a tracking device positioned within the subject. The determined location of the tracking device can be used to determine which frame of the image data to display at a selected time.

    摘要翻译: 本公开涉及获取被摄体的图像数据并选择要显示的图像数据。 图像数据可以包括与定位在对象内的跟踪装置的特定位置有关的多个帧。 可以使用确定的跟踪设备的位置来确定在所选择的时间显示的图像数据的哪个帧。

    Stylet for use with image guided systems
    26.
    发明授权
    Stylet for use with image guided systems 失效
    用于图像引导系统的探针

    公开(公告)号:US08204574B2

    公开(公告)日:2012-06-19

    申请号:US12275377

    申请日:2008-11-21

    IPC分类号: A61B5/05

    摘要: A stylet for an image guided system, which includes a locating device and which is operable for emitting an electromagnetic field for locating the stylet. The stylet includes a flexible elongate member, an electrically conductive member, and a reinforcement member. The reinforcement member is disposed inside the electrically conductive member and is made out of a magnetic material. The reinforcement member reinforces the stylet and provides electrical communication between the conductive member and the locating device such that current induced in the conductive member is transmitted to the locating device via the reinforcement member.

    摘要翻译: 用于图像引导系统的探针,其包括定位装置,其可操作用于发射用于定位探针的电磁场。 探针包括柔性细长构件,导电构件和加强构件。 加强构件设置在导电构件的内部并由磁性材料制成。 该加强构件加强探针并且在导电构件和定位装置之间提供电连通,使得在导电构件中感应的电流经由加强构件传递至定位装置。

    SUBCUTANEOUS LEAD GUIDANCE
    27.
    发明申请
    SUBCUTANEOUS LEAD GUIDANCE 有权
    SUBCUTANEO领导指导

    公开(公告)号:US20100125194A1

    公开(公告)日:2010-05-20

    申请号:US12503298

    申请日:2009-07-15

    IPC分类号: A61B5/055 A61B6/12 G08B21/00

    摘要: An apparatus for subcutaneous lead guidance includes a flexible guide strap, a navigation catheter and a tunneling tool. The guide strap includes an upper layer having a plurality of retainer formations and a substrate attachable on a patient's skin extending between an incision and a target site. The navigation catheter is coupled to the upper layer via the retainer formations from a first end to a second end of the guide strap. The navigation catheter includes a plurality of position sensors for generating a subcutaneous navigation volume between the incision and the target site when the navigation catheter is coupled to a navigation system. The tunneling tool has a distal portion with a leading end and at least one position sensor on the distal portion for viewing digital representation of the distal portion in relation to the navigation volume on a display coupled to the navigation system.

    摘要翻译: 用于皮下引导引导的装置包括柔性引导带,导航导管和隧道工具。 引导带包括具有多个保持架结构的上层和可在切口和目标部位之间延伸的病人皮肤上的基底。 导航导管通过保持器结构从引导带的第一端到第二端连接到上层。 导航导管包括多个位置传感器,用于当导航导管联接到导航系统时,在切口和目标部位之间产生皮下导航体积。 隧道工具具有远端部分,前端部分和远端部分上的至少一个位置传感器,用于在与导航系统相连的显示器上相对于导航体积观察远端部分的数字表示。

    STYLET FOR USE WITH IMAGE GUIDED SYSTEMS
    28.
    发明申请
    STYLET FOR USE WITH IMAGE GUIDED SYSTEMS 失效
    与图像引导系统一起使用的样式

    公开(公告)号:US20100130851A1

    公开(公告)日:2010-05-27

    申请号:US12275377

    申请日:2008-11-21

    IPC分类号: A61B5/055

    摘要: A stylet for an image guided system, which includes a locating device and which is operable for emitting an electromagnetic field for locating the stylet. The stylet includes a flexible elongate member, an electrically conductive member, and a reinforcement member. The reinforcement member is disposed inside the electrically conductive member and is made out of a magnetic material. The reinforcement member reinforces the stylet and provides electrical communication between the conductive member and the locating device such that current induced in the conductive member is transmitted to the locating device via the reinforcement member.

    摘要翻译: 用于图像引导系统的探针,其包括定位装置,其可操作用于发射用于定位探针的电磁场。 探针包括柔性细长构件,导电构件和加强构件。 加强构件设置在导电构件的内部并由磁性材料制成。 该加强构件加强探针并且在导电构件和定位装置之间提供电连通,使得在导电构件中感应的电流经由加强构件传递到定位装置。