公开(公告)号：US09693721B2

公开(公告)日：2017-07-04

申请号：US14742137

申请日：2015-06-17

Applicant: DexCom, Inc.

Inventor： Robert J. Boock ,  Monica A. Rixman ,  Huashi Zhang ,  Michael J. Estes ,  Kristina Lawrence

IPC: A61B5/1486 ,  A61B5/1468 ,  G01N27/40 ,  A61B5/1473 ,  A61B5/145 ,  C12Q1/00 ,  A61B5/00

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/7203 ,  B33Y70/00 ,  C12Q1/006 ,  G01N27/40

Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.

公开(公告)号：US20160073939A1

公开(公告)日：2016-03-17

申请号：US14952317

申请日：2015-11-25

Applicant: DexCom, Inc.

Inventor： Robert J. Boock ,  Monica A. Rixman ,  Huashi Zhang ,  Michael J. Estes ,  Kristina Lawrence

IPC: A61B5/1486 ,  A61B5/145

CPC classification number: C12Q1/002 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1486 ,  A61B5/14865 ,  C12Q1/006

Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.

公开(公告)号：US20160007897A1

公开(公告)日：2016-01-14

申请号：US14861963

申请日：2015-09-22

Applicant: DexCom, Inc.

Inventor： Robert Boock ,  Monica Rixman Swinney ,  Huashi Zhang ,  Michael J. Estes ,  Kristina Lawrence

IPC: A61B5/1486 ,  A61B5/00 ,  A61B5/145

CPC classification number: A61B5/14865 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/72 ,  A61B5/7475 ,  B33Y70/00 ,  C12Q1/006 ,  G01N27/40

Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.

公开(公告)号：US20150351672A1

公开(公告)日：2015-12-10

申请号：US14717965

申请日：2015-05-20

Applicant: DexCom, Inc.

Inventor： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif N. Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Rack-Gomer ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Dmytro Sokolovsky

IPC: A61B5/1495 ,  A61B5/01 ,  A61B5/1486 ,  A61B5/145 ,  A61B5/053 ,  A61B5/00 ,  A61B5/11

CPC classification number: A61B5/1495 ,  A61B5/01 ,  A61B5/053 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/4833 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/6898 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/746 ,  A61B2560/0247 ,  A61B2560/0252 ,  A61B2560/0276 ,  A61B2560/0475 ,  A61B2562/0247 ,  A61M5/1723 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2230/201 ,  G06F19/00

Abstract: Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

公开(公告)号：US20150351671A1

公开(公告)日：2015-12-10

申请号：US14717904

申请日：2015-05-20

Applicant: DexCom, Inc.

Inventor： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif N. Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Rack-Gomer ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Dmytro Sokolovsky

IPC: A61B5/1495 ,  A61B5/145 ,  A61M5/172 ,  A61B5/053 ,  A61B5/00 ,  A61B5/1473 ,  A61B5/01

CPC classification number: A61B5/1495 ,  A61B5/01 ,  A61B5/053 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/4833 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/6898 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/746 ,  A61B2560/0247 ,  A61B2560/0252 ,  A61B2560/0276 ,  A61B2560/0475 ,  A61B2562/0247 ,  A61M5/1723 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2230/201 ,  G06F19/00

Abstract: Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

公开(公告)号：US20150090589A1

公开(公告)日：2015-04-02

申请号：US14567293

申请日：2014-12-11

Applicant: DexCom, Inc.

Inventor： Michael J. Estes ,  Jennifer Blackwell ,  Sebastian Bohm ,  Robert J. Boock ,  Jack Pryor ,  Peter C. Simpson ,  Matthew D. Wightlin

IPC: G01N27/403

Abstract: Systems and methods for compensating for effects of temperature on implantable sensors are provided. In some embodiments, systems and methods are provided for measuring a temperature to determine a change in temperature in a sensor environment. In certain embodiments, a temperature compensation factor is determined based on a change in temperature of the sensor environment. The temperature compensation factor can be used in processing raw data of an analyte signal to report a more accurate analyte concentration.

Abstract translation: 提供了用于补偿温度对植入式传感器的影响的系统和方法。 在一些实施例中，提供了用于测量温度以确定传感器环境中的温度变化的系统和方法。 在某些实施例中，基于传感器环境的温度变化来确定温度补偿系数。 温度补偿因子可用于处理分析物信号的原始数据，以报告更准确的分析物浓度。

公开(公告)号：US20140005508A1

公开(公告)日：2014-01-02

申请号：US13747746

申请日：2013-01-23

Applicant: DEXCOM, INC.

Inventor： Michael J. Estes ,  Jennifer Blackwell ,  Sebastian Bohm ,  Robert J. Boock ,  Jack Pryor ,  Peter C. Simpson ,  Matthew D. Wightlin

IPC: A61B5/145

CPC classification number: G01N27/403 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/1495

Abstract: Systems and methods for compensating for effects of temperature on implantable sensors are provided. In some embodiments, systems and methods are provided for measuring a temperature to determine a change in temperature in a sensor environment. In certain embodiments, a temperature compensation factor is determined based on a change in temperature of the sensor environment. The temperature compensation factor can be used in processing raw data of an analyte signal to report a more accurate analyte concentration.

Abstract translation: 提供了用于补偿温度对植入式传感器的影响的系统和方法。 在一些实施例中，提供了用于测量温度以确定传感器环境中的温度变化的系统和方法。 在某些实施例中，基于传感器环境的温度变化来确定温度补偿系数。 温度补偿因子可用于处理分析物信号的原始数据，以报告更准确的分析物浓度。

公开(公告)号：US20240183818A1

公开(公告)日：2024-06-06

申请号：US18535815

申请日：2023-12-11

Applicant: Dexcom, Inc.

Inventor： Michael J. Estes ,  Jennifer Blackwell ,  Sebastian Böhm ,  Robert J. Boock ,  Jack Pryor ,  Peter C. Simpson ,  Matthew D. Wightlin

IPC: G01N27/403 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1495

CPC classification number: G01N27/403 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/1495

Abstract: Systems and methods for compensating for effects of temperature on implantable sensors are provided. In some embodiments, systems and methods are provided for measuring a temperature to determine a change in temperature in a sensor environment. In certain embodiments, a temperature compensation factor is determined based on a change in temperature of the sensor environment. The temperature compensation factor can be used in processing raw data of an analyte signal to report a more accurate analyte concentration.

公开(公告)号：US11892426B2

公开(公告)日：2024-02-06

申请号：US17163083

申请日：2021-01-29

Applicant: DexCom, Inc.

Inventor： Michael J. Estes ,  Jennifer Blackwell ,  Sebastian Bohm ,  Robert J. Boock ,  Jack Pryor ,  Peter C. Simpson ,  Matthew D. Wightlin

IPC: G01N27/403 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1495

CPC classification number: G01N27/403 ,  A61B5/1495 ,  A61B5/14532 ,  A61B5/14865

Abstract: Systems and methods for compensating for effects of temperature on implantable sensors are provided. In some embodiments, systems and methods are provided for measuring a temperature to determine a change in temperature in a sensor environment. In certain embodiments, a temperature compensation factor is determined based on a change in temperature of the sensor environment. The temperature compensation factor can be used in processing raw data of an analyte signal to report a more accurate analyte concentration.

公开(公告)号：US20210275063A1

公开(公告)日：2021-09-09

申请号：US17156393

申请日：2021-01-22

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Jennifer Blackwell ,  Sebastian Bohm ,  Michael J. Estes ,  Jeff Jackson ,  Jason Mitchell ,  Jack Pryor ,  Daiting Rong ,  Sean T. Saint ,  Disha B. Sheth ,  Shanger Wang

IPC: A61B5/1473 ,  A61B5/145 ,  A61B5/00 ,  A61B17/34

Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.