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公开(公告)号：US07575558B2
公开(公告)日：2009-08-18
申请号：US10892874
申请日：2004-07-16
IPC分类号： A61B5/00
CPC分类号： A61M5/142 , A61B5/0002 , A61B5/145 , A61B5/14532 , A61B5/150022 , A61B5/150221 , A61B5/150412 , A61B5/150503 , A61B5/150755 , A61B5/150854 , A61B5/15113 , A61B5/15117 , A61B5/15121 , A61B5/15123 , A61B5/1519 , A61M2205/3576 , G06F19/00 , H04L67/025 , H04L67/1097 , H04L67/12 , Y10S128/903
摘要： A portable medical analyzer comprising a sampling module with a sample port for receiving body fluid, an assay sensor module for analysis of the body fluid, an analytical detector module with detection of information from the assay, and a communications module for transferring the information to a remote location via a wired or wireless network.
摘要翻译： 一种便携式医学分析仪，包括具有用于接收体液的采样端口的采样模块，用于分析体液的测定传感器模块，具有来自测定的信息检测的分析检测器模块，以及用于将信息传送到 通过有线或无线网络进行远程位置。
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公开(公告)号：US07563232B2
公开(公告)日：2009-07-21
申请号：US10335215
申请日：2002-12-31
申请人： Dominique M. Freeman , Dirk Boecker , Don Alden
发明人： Dominique M. Freeman , Dirk Boecker , Don Alden
IPC分类号： A61B5/00
CPC分类号： A61B5/1519 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B5/742 , A61B17/32093 , A61M5/158 , A61M5/172 , A61M2005/004 , A61M2005/1585 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905 , G01N33/557
摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. An analyte detecting member is positioned to receive fluid from a wound created by the penetrating member. The detection member is configured to determine a concentration of an analyte in the fluid using a sample of less than 1 mL of the fluid. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.
摘要翻译： 本发明的这些和其它目的是在包括电动驱动力发生器的组织部位上使用的体液取样系统中实现的。 穿透构件可操作地联接到力发生器。 力产生器将构件沿着路径移动离开具有穿透构件出口的壳体，进入组织部位，在组织部位停止，并从组织部位抽出。 分析物检测构件定位成从由穿透构件产生的伤口接收流体。 检测构件被配置为使用小于1mL的流体的样品来确定流体中的分析物的浓度。 用户界面被配置为中继穿透构件性能或穿透构件设置中的至少一种。
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公开(公告)号：US07491178B2
公开(公告)日：2009-02-17
申请号：US10335052
申请日：2002-12-31
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： A body fluid sampling system for use on a tissue site has a housing and a penetrating member driver at least partially within the housing. At least one disposable is within the housing. The disposable includes an analyte sensor in a sample chamber that is configured to receive body fluid from a wound in tissue created by a penetrating member. A penetrating member is associated with the sample chamber. Each penetrating member and its associated sample chamber have a combined occupied volume of no more than about 5.0 cm3.
摘要翻译： 用于组织部位的体液采样系统具有至少部分地在壳体内的壳体和穿透构件驱动器。 至少一个一次性在外壳内。 一次性包括样品室中的分析物传感器，其被构造成从穿透构件产生的组织中的伤口接收体液。 穿透构件与样品室相关联。 每个穿透构件及其相关联的样品室具有不超过约5.0cm 3的组合占用体积。
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公开(公告)号：US07232451B2
公开(公告)日：2007-06-19
申请号：US10335217
申请日：2002-12-31
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
IPC分类号： A61B17/32
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： A skin penetrating system has a housing member and a plurality of penetrating members positioned in the housing member. A tissue stabilizing device is coupled to the housing member. A user interface is configured to relay at least one of, skin penetrating performance or a skin penetrating setting.
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公开(公告)号：US07892183B2
公开(公告)日：2011-02-22
申请号：US10613517
申请日：2003-07-03
申请人： Dirk Boecker , Dominique M. Freeman , Don Alden
发明人： Dirk Boecker , Dominique M. Freeman , Don Alden
CPC分类号： A61B5/15146 , A61B5/14532 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150183 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/15151 , A61B5/15161 , A61B5/15169 , A61B5/15171 , A61B5/15176 , A61B5/157
摘要： A body fluid sampling system is provided for use on a tissue site. In one embodiment, the system comprises a cartridge; a penetrating member driver; a plurality of penetrating members arranged in a radial configuration on the cartridge wherein sharpened distal tips of the penetrating members point radially outward; wherein an active one of the penetrating members may be operatively coupled to the penetrating member driver, the penetrating member driver moving the active one along a path out of a housing having a penetrating member exit, into the tissue site, stopping in the tissue site, and withdrawing out of the tissue site; and a plurality of analyte detecting members, wherein at least one of the analyte detecting members is positioned to receive fluid from a wound created by the active one of the penetrating members, wherein the detecting members are not pierced by the active one of the penetrating members.
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公开(公告)号：US07850621B2
公开(公告)日：2010-12-14
申请号：US10559223
申请日：2004-06-07
申请人： Barry Dean Briggs , Travis Marsot , Jason Hegener , Dominique M. Freeman , Dirk Boecker , Don Alden , Matt Schumann , Mike Beadman
发明人： Barry Dean Briggs , Travis Marsot , Jason Hegener , Dominique M. Freeman , Dirk Boecker , Don Alden , Matt Schumann , Mike Beadman
CPC分类号： A61B5/157 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150412 , A61B5/150755 , A61B5/15113 , A61B5/15123 , A61B5/15151 , A61B5/15161
摘要： A method of controlling a penetrating member is provided. The method comprises providing a lancing device comprising a penetrating member driver having a position sensor and a processor that can determine the relative position and velocity of the penetrating member based on measuring relative position of the penetrating member with respect to time; providing a predetermined velocity control trajectory based on a model of the driver and a model of tissue to be contacted. In some embodiments, a feedforward control to maintain penetrating member velocity along said trajectory.
摘要翻译： 提供了一种控制穿透构件的方法。 该方法包括提供穿刺装置，其包括具有位置传感器和处理器的穿透构件驱动器，所述穿透构件驱动器可以基于测量穿透构件相对于时间的相对位置来确定穿透构件的相对位置和速度; 基于驾驶员的模型和待接触的组织的模型提供预定的速度控制轨迹。 在一些实施例中，前馈控制器沿着所述轨迹保持穿透构件速度。
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公开(公告)号：US20100274157A1
公开(公告)日：2010-10-28
申请号：US12797706
申请日：2010-06-10
申请人： Barry Dean Briggs , Travis Marsot , Jason Hegener , Dominique M. Freeman , Dirk Boecker , Don Alden , Matt Schumann , Mike Beadman
发明人： Barry Dean Briggs , Travis Marsot , Jason Hegener , Dominique M. Freeman , Dirk Boecker , Don Alden , Matt Schumann , Mike Beadman
IPC分类号： A61B5/151
CPC分类号： A61B5/157 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150412 , A61B5/150755 , A61B5/15113 , A61B5/15123 , A61B5/15151 , A61B5/15161
摘要： A method of controlling a penetrating member is provided. The method comprises providing a lancing device comprising a penetrating member driver having a position sensor and a processor that can determine the relative position and velocity of the penetrating member based on measuring relative position of the penetrating member with respect to time; providing a predetermined velocity control trajectory based on a model of the driver and a model of tissue to be contacted. In some embodiments, a feedforward control to maintain penetrating member velocity along said trajectory.
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28.发明授权公开(公告)号：US07699791B2
公开(公告)日：2010-04-20
申请号：US10363509
申请日：2002-06-12
申请人： Don Alden , Dominique M. Freeman , Paul Lum , Vladimir Drbal , Dirk Boecker , Edward D. Verdonk
发明人： Don Alden , Dominique M. Freeman , Paul Lum , Vladimir Drbal , Dirk Boecker , Edward D. Verdonk
IPC分类号： A61B5/00
CPC分类号： A61B5/150022 , A61B5/150061 , A61B5/150068 , A61B5/150083 , A61B5/150099 , A61B5/150167 , A61B5/150427 , A61B5/150503
摘要： Blood samples can be collected without substantial contamination from ambient air, such that the blood sample may be analyzed accurately for gaseous components such as oxygen and carbon dioxide. An embodiment of the device has integrated actuation, lancing, and sample acquisition components, which in some embodiments are miniatuized and/or disposable.
摘要翻译： 可以收集血液样本而没有来自环境空气的实质污染，使得可以准确地分析血液样品用于气体组分如氧气和二氧化碳。 该装置的一个实施例具有集成的致动，采血和采样部件，其在一些实施例中是微型化和/或一次性的。
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公开(公告)号：US07648469B2
公开(公告)日：2010-01-19
申请号：US12023615
申请日：2008-01-31
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150358 , A61B5/150427 , A61B5/150503 , A61B5/150572 , A61B5/15087 , A61B5/151 , A61B5/15113 , A61B5/15123 , A61B5/15146 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/15184 , A61B5/15186 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. An analyte detecting member is positioned to receive fluid from a wound created by the penetrating member. The detection member is configured to determine a concentration of an analyte in the fluid using a sample of less than 1 μL of the fluid.
摘要翻译： 本发明的这些和其它目的是在包括电动驱动力发生器的组织部位上使用的体液取样系统中实现的。 穿透构件可操作地联接到力发生器。 力产生器将构件沿着路径移动离开具有穿透构件出口的壳体，进入组织部位，在组织部位停止，并从组织部位抽出。 分析物检测构件定位成从由穿透构件产生的伤口接收流体。 检测构件被配置为使用小于1μl流体的样品来确定流体中分析物的浓度。
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公开(公告)号：US07547287B2
公开(公告)日：2009-06-16
申请号：US10335212
申请日：2002-12-31
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
IPC分类号： A61B5/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150358 , A61B5/150427 , A61B5/150503 , A61B5/150572 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15176 , A61B5/15178 , A61B5/15184 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： A tissue penetrating system has a housing member. A plurality of penetrating members are positioned in the housing member. A tissue stabilizing member is coupled to the housing. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.
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