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    Multiple lancet device
    4.
    发明授权
    Multiple lancet device 失效
    多重刺血针装置

    公开(公告)号：US06660018B2

    公开(公告)日：2003-12-09

    申请号：US09846139

    申请日：2001-04-30

    申请人： Paul Lum ,  Michael Greenstein ,  Leslie A. Leonard ,  Dominique M Freeman

    发明人： Paul Lum ,  Michael Greenstein ,  Leslie A. Leonard ,  Dominique M Freeman

    IPC分类号： A61B1714

    CPC分类号： A61B5/150977 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150099 ,  A61B5/150396 ,  A61B5/150427 ,  A61B5/15142 ,  A61B5/157 ,  A61B17/205

    摘要： A device for puncturing the skin of a patient. The device includes first and second protrusions, each protrusion puncturing the skin when pressed against the skin. The first and second protrusions are arranged such that the first protrusion punctures the skin at a location less than a predetermined distance from the second protrusion. The distance is chosen to be less than the discriminatable distance between distinct pain perception points in the patient, such that the patient perceives a single puncture when the first and second protrusions puncture the skin. In one embodiment of the invention, the device includes a base lip that applies a lateral force to the skin when the base lip is pressed against the skin. In this embodiment, the protrusions are pressed into the skin as the base lip is pressed against the skin.

    摘要翻译： 一种用于刺穿患者皮肤的装置。 该装置包括第一和第二突起，每个突出部在压靠皮肤时刺入皮肤。 第一突起和第二突起被布置成使得第一突起在距离第二突起小于预定距离的位置刺穿皮肤。 该距离选择为小于患者中不同疼痛感知点之间的可区分距离，使得当第一和第二突起刺穿皮肤时，患者感知到单次穿刺。 在本发明的一个实施例中，所述装置包括基底唇部，当基底唇被压靠在皮肤上时，所述基部唇缘向皮肤施加横向力。 在该实施例中，当基底唇被压在皮肤上时，突起被压入皮肤。

    Extraction and transportation of blood for analysis
    5.
    发明授权
    Extraction and transportation of blood for analysis 有权
    提取和运输血液进行分析

    公开(公告)号：US06364890B1

    公开(公告)日：2002-04-02

    申请号：US09614318

    申请日：2000-07-12

    申请人： Paul Lum ,  Leslie A. Leonard ,  Edward D. Verdonk ,  Dominique M. Freeman ,  Michael Greenstein ,  Catherine Keely-Templin

    发明人： Paul Lum ,  Leslie A. Leonard ,  Edward D. Verdonk ,  Dominique M. Freeman ,  Michael Greenstein ,  Catherine Keely-Templin

    IPC分类号： A61B1732

    CPC分类号： A61B5/15144 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150106 ,  A61B5/150427 ,  A61B5/150969 ,  A61B5/150984 ,  A61B5/15113

    摘要： A device for sampling blood from the skin of a patient by puncture. The device includes one or more lancets for lancing the skin and a fluid-conducting plate unit for transporting blood from the lancing wound. The plate unit has one or more channels for conducting fluid to one or more target locations. Preferably there is a first channel for conducting away a first portion of fluid that contains more of a fluid that is emitted initially (initial fluid) from the puncture wound and a second channel for conducting a second portion of fluid that contains less of the initial fluid from the puncture wound. Blood is drawn into the channels by capillary force. The device can be used to lance the skin and obtain a representative sample of blood with relatively simple procedures.

    摘要翻译： 一种用于通过穿刺从患者皮肤取样血液的装置。 该装置包括用于切割皮肤的一个或多个刺血针和用于从穿刺伤口输送血液的导流板单元。 板单元具有用于将流体传导到一个或多个目标位置的一个或多个通道。 优选地，存在用于传导第一部分流体的第一通道，所述第一部分流体包含更多的来自穿刺伤口的最初发射的流体（初始流体）和用于传导含有较少初始流体的第二部分流体的第二通道 从穿刺伤口。 通过毛细血管力将血液吸入通道。 该装置可用于以相对简单的程序来刺激皮肤并获得代表性的血液样品。

    Portable Preparation, Analysis, and Detection Apparatus for Nucleic Acid Processing
    9.
    发明申请
    Portable Preparation, Analysis, and Detection Apparatus for Nucleic Acid Processing 审中-公开
    用于核酸加工的便携式制备，分析和检测装置

    公开(公告)号：US20090321259A1

    公开(公告)日：2009-12-31

    申请号：US12433201

    申请日：2009-04-30

    申请人： Charles S. Vann ,  Michael Greenstein ,  yuh-Min Chiang

    发明人： Charles S. Vann ,  Michael Greenstein ,  yuh-Min Chiang

    IPC分类号： C12Q1/68 ,  G01N27/447

    CPC分类号： G01N27/447 ,  C12M47/06 ,  C12Q1/6806 ,  C12Q1/686

    摘要： The present teachings comprise a device and method for lysing and/or purifying biological sample. The device can comprise a cartridge having a chamber containing a biological sample receiving region, a plurality of electrodes, and one or more sieving matrices. The electrodes can be configured to lyse the biological sample through the production of a pulsed electrical field. The electrodes can also be configured to heat lyse the biological sample. The electrodes can also be configured to electrophoretically move the biological sample through one or more sieving matrices. A portion of the sample can be isolated on a membrane. The portion of the sample isolated on the membrane can be amplified and detected. A portion of the sample can be isolated in a collection area present in the cartridge. The portion of the sample isolated in the collection area can be removed from the cartridge.

    摘要翻译： 本教导包括用于裂解和/或纯化生物样品的装置和方法。 该装置可以包括具有包含生物样品接收区域，多个电极和一个或多个筛分基质的腔室的药筒。 电极可以被配置成通过产生脉冲电场来裂解生物样品。 电极也可以被配置为热裂解生物样品。 电极还可以被配置成通过一个或多个筛分基质电泳移动生物样品。 样品的一部分可以在膜上分离。 可以扩增和检测在膜上分离的样品的部分。 样品的一部分可以在存在于盒中的收集区域中分离。 分离在收集区域中的样品的部分可以从盒中取出。