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    CATHETER-BASED CLUTCHED HEART VALVE SIZER
    21.
    发明申请
    CATHETER-BASED CLUTCHED HEART VALVE SIZER 审中-公开
    基于导管的离合器心瓣尺寸

    公开(公告)号：US20160183843A1

    公开(公告)日：2016-06-30

    申请号：US15063353

    申请日：2016-03-07

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Da-Yu Chang

    IPC: A61B5/107 ,  A61B5/02 ,  A61B5/00 ,  A61F2/24

    CPC classification number: A61B5/1076 ,  A61B5/02028 ,  A61B5/6859 ,  A61B2090/064 ,  A61B2090/065 ,  A61B2090/066 ,  A61F2/243 ,  A61F2/2496

    Abstract: A valve sizer for determining an appropriate replacement valve size when performing a heart valve replacement procedure is provided. In one version the valve sizer has a hollow shaft with proximal and distal ends. A movable sizing element couples to the distal end of the shaft and is radially expandable between first, contracted and second, expanded positions. An actuator assembly on a handle includes an actuator coupled to a clutch member via a ball-spring-detent clutch. A rod extends through the shaft and maintains a fixed distance between the handle and a distal hub in the sizing element. Movement of the actuator causes axial movement of the shaft, thereby causing radial expansion of sizing petals relative to the hub. The clutch slips when a predetermined reaction force from the surrounding valve annulus is met by the petals.

    Abstract translation: 提供了一种用于在执行心脏瓣膜置换过程时确定适当的更换瓣膜尺寸的瓣膜分选机。 在一个版本中，阀门分级器具有中空轴，其具有近端和远端。 可移动的施胶元件联接到轴的远端并且可在第一，收缩和第二扩展位置之间径向扩张。 手柄上的致动器组件包括经由球弹簧止动离合器联接到离合器构件的致动器。 杆延伸穿过轴并且在手柄和施胶元件中的远侧轮毂之间保持固定的距离。 致动器的运动导致轴的轴向移动，从而引起尺寸花瓣相对于毂的径向膨胀。 当来自周围的瓣膜环的预定反作用力被花瓣满足时，离合器滑动。

    SURGICAL HEART VALVES IDENTIFIABLE POST-IMPLANT
    22.
    发明申请
    SURGICAL HEART VALVES IDENTIFIABLE POST-IMPLANT 有权
    外科心脏瓣膜识别后植入物

    公开(公告)号：US20150366664A1

    公开(公告)日：2015-12-24

    申请号：US14745287

    申请日：2015-06-19

    Applicant: Edwards Lifesciences Corporation

    Inventor： Jessica Guttenberg ,  Da-Yu Chang ,  Derrick Johnson ,  Brian S. Conklin ,  Qinggang Zeng ,  Myron Howanec, JR. ,  Grace M. Kim

    IPC: A61F2/24 ,  A61F2/91

    CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2250/0085 ,  A61F2250/0089 ,  A61F2250/0098

    Abstract: A prosthetic heart valve configured to replace a native heart valve and for post-implant expansion and having a valve-type indicator thereon visible from outside the body post-implant. The indicator communicates information about the valve, such as the size or orifice diameter of the valve, and/or that the valve has the capacity for post-implant expansion. The indicator can be an alphanumeric symbol or other symbol or combination of symbols that represent information about the characteristics of the valve such as the valve size. The capacity for post-implant expansion facilitates a valve-in-valve procedure, where the valve-type indicator conveys information to the surgeon about whether the implanted valve is suitable for the procedure and informs the choice of the secondary valve.

    Abstract translation: 一种假体心脏瓣膜，其构造成代替天然心脏瓣膜并用于植入后扩张，并且在体外植入物后面具有可从其上观察到的瓣膜型指示器。 指示器传达关于阀的信息，例如阀的尺寸或孔直径，和/或阀具有用于植入物扩张的能力。 指示符可以是代表关于阀的特性的信息的字母数字符号或其他符号或符号的组合，例如阀的尺寸。 植入后扩张的能力有利于瓣膜瓣膜手术，其中瓣膜型指示器向外科医生传达关于植入的瓣膜是否适于手术并且通知二次瓣膜的选择的信息。

    METHODS OF DEPLOYING KNOTLESS SUTURE ANCHORING CLAMPS
    23.
    发明申请
    METHODS OF DEPLOYING KNOTLESS SUTURE ANCHORING CLAMPS 有权
    分配无缝锚固锚杆的方法

    公开(公告)号：US20150313590A1

    公开(公告)日：2015-11-05

    申请号：US14797112

    申请日：2015-07-11

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Louis A. Campbell ,  Salvador Marquez ,  Donald E. Bobo, JR.

    IPC: A61B17/04 ,  A61F2/24

    CPC classification number: A61B17/0487 ,  A61B17/0401 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0416 ,  A61B2017/0464 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61F2/24 ,  A61F2/2409 ,  A61F2/2442

    Abstract: Methods of deploying knotless suture locking clamps for securing prostheses such as heart valves or annuloplasty rings to facilitate implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.

    Abstract translation: 部署用于固定假体（例如心脏瓣膜或瓣环成形术环）的无缝缝合锁定夹具的方法以便于植入。 夹具具有相对的夹具半部，该半部由通向一侧的狭槽分开，并被诸如一个或多个C形夹弹簧的偏置构件包围。 缝合线横向穿过狭槽，狭槽由位于夹子半部之间的保持构件保持打开。 锁定夹具沿着缝合线滑动到适当位置，调节缝合线的张力，并且移除保持构件以允许偏置构件将缝合线夹在夹具半部之间。 用于传送和展开锁定夹具的输送工具在堆叠中的输送管内包含多个夹具，并且为了安全而将其粘合在一起并具有公共保持构件。 该工具在一侧具有用于进入缝合线的纵向通道。

    HYBRID HEART VALVES
    25.
    发明公开
    HYBRID HEART VALVES 审中-公开

    公开(公告)号：US20230285145A1

    公开(公告)日：2023-09-14

    申请号：US18308439

    申请日：2023-04-27

    Applicant: EDWARDS LIFESCIENCES CORPORATION

    Inventor： Brian S. Conklin ,  Qinggang Zeng ,  Myron Howanec, JR. ,  Grace Myong Kim

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2210/0057 ,  A61F2230/0069 ,  A61F2250/006 ,  A61F2250/0097 ,  A61F2220/0075 ,  A61F2250/0048 ,  A61F2250/0018 ,  A61F2250/001

    Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible to a limited degree for delivery and expandable post-implant to facilitate a valve-in-valve (ViV) procedure. The hybrid heart valves eliminate earlier structural bands, which both reduces manufacturing time and facilitates a ViV procedure.

    MINIMALLY-INVASIVE LOW STRAIN ANNULOPLASTY RING
    27.
    发明申请
    MINIMALLY-INVASIVE LOW STRAIN ANNULOPLASTY RING 有权

    公开(公告)号：US20230125047A1

    公开(公告)日：2023-04-20

    申请号：US18069082

    申请日：2022-12-20

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Louis A. Campbell ,  Salvador Marquez ,  James R. Yamada ,  Rodolfo Rodriguez ,  Da-Yu Chang ,  Steven M. Ford

    IPC: A61F2/24

    Abstract: A minimally-invasive annuloplasty ring for implant at a mitral annulus. The annuloplasty ring has an inner core member with a C-shaped plan view that generally defines an oval with a major axis and a minor axis, and is symmetric about the minor axis. A posterior portion of the core member bisected by the minor axis has a thicker radial dimension than a pair of free end regions terminating on an anterior side of the core member. The radial thickness smoothly transitions between the posterior portion and the end regions. The inner core member may be covered with a fabric, and is a superelastic metal so that it can be straightened out and delivered through an access tube. The curvatures and thicknesses around the core member are selected so that the strain experienced when straightened does not exceed 7-8%.

    ENHANCED FLEXIBILITY ANNULOPLASTY BANDS
    28.
    发明申请
    ENHANCED FLEXIBILITY ANNULOPLASTY BANDS 有权

    公开(公告)号：US20220370200A1

    公开(公告)日：2022-11-24

    申请号：US17817231

    申请日：2022-08-03

    Applicant: Edwards Lifesciences Corporation

    Inventor： Rodolfo Rodriguez ,  Brian S. Conklin ,  Louis A. Campbell

    IPC: A61F2/24

    Abstract: An annuloplasty band having a differentiation in area moment of inertia, where the area moment of inertia in the out of plane direction is much less than the area moment of inertia in the plane of the annulus. This makes the band stiff enough to hold the annulus in the correct shape while being flexible enough out of plane to minimize the risk of suture dehiscence or breakage. One example is a C-shaped band with a core formed of nitinol and having a constant cross-section with a wider radial dimension than an axial dimension. The cross-section may be rectangular. The band is asymmetric across a minor axis with one end extending around the anterior side farther than the other. The free ends rise up from adjacent lateral sides, and a continuous posterior mid-section also rises upward.

    PROSTHETIC VALVE HOLDERS WITH AUTOMATIC DEPLOYING MECHANISMS
    29.
    发明申请
    PROSTHETIC VALVE HOLDERS WITH AUTOMATIC DEPLOYING MECHANISMS 有权

    公开(公告)号：US20220331100A1

    公开(公告)日：2022-10-20

    申请号：US17810206

    申请日：2022-06-30

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Michael C. Murad

    IPC: A61F2/24

    Abstract: A valve holder for delivering a prosthetic heart valve to an implant site is in various embodiments configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. The valve holder can be configured to deploy or actuate automatically when performing preparatory steps that are already familiar to practitioners, such as attaching a delivery handle to the valve holder, so that the valve holders will not require additional steps or training to use. Therefore, operation of the valve holders is kept simple, and occurrences of mistakes caused by user error can be minimized or reduced. Valve holders according to different embodiments can be designed to accommodate implantation of prosthetic heart valves from either the inflow end or the outflow end of the native valve annulus.

    METHOD FOR DELIVERING A SURGICAL HEART VALVE
    30.
    发明申请
    METHOD FOR DELIVERING A SURGICAL HEART VALVE 有权

    公开(公告)号：US20220280290A1

    公开(公告)日：2022-09-08

    申请号：US17664619

    申请日：2022-05-23

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin

    IPC: A61F2/24

    Abstract: Valve holders and introducers for delivering a prosthetic heart valve to an implant site are configured to facilitate insertion of prosthetic valves through small incisions or access sites on a patient's body. The valve holders can also be configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. A valve holder according to embodiments of the invention includes features that reduce or eliminate mistakes during implantation of the prosthetic valves, such as a handle that prevents implantation of the valve prior to proper deployment or adjustment of the holder. An introducer is provided which can facilitate temporary deformation of a nitinol prosthetic valve to pass between adjacent ribs of a patient without rib spreading. Valves are provided having a wireform and stiffener band made of materials that exhibit superelastic properties. Valve holders, introducers, and valves according to the various embodiments can be used in minimally invasive procedures, such as thoracotomy procedures.

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