公开(公告)号：US20190307589A1

公开(公告)日：2019-10-10

申请号：US16378417

申请日：2019-04-08

Applicant: Edwards Lifesciences Corporation

Inventor： Eran Goldberg ,  Noa Axelrod ,  Yair A. Neumann ,  Boaz Manash ,  David Maimon ,  Eyal Leiba ,  Ralph Schneider ,  Liron Tayeb

IPC: A61F2/966 ,  A61M29/00

Abstract: An expandable sheath is disclosed herein, which has a first polymeric layer and a braided layer positioned radially outward of the first polymeric layer. The braided layer includes a plurality of filaments braided together. The expandable sheaths further include a resilient elastic layer positioned radially outward of the braided layer. The elastic layer is configured to apply radial force to the braided layer and the first polymeric layer. The expandable sheath further includes a second polymeric layer positioned radially outward of the elastic layer and bonded to the first polymeric layer such that the braided layer and the elastic layer are encapsulated between the first and second polymeric layers. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.

公开(公告)号：US20250090315A1

公开(公告)日：2025-03-20

申请号：US18965594

申请日：2024-12-02

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Liron Tayeb ,  Eran Goldberg ,  David Maimon ,  Adi Carmi ,  Arie Tylis ,  Tomer Saar ,  Anatoly Dvorsky

IPC: A61F2/24 ,  A61F2/88 ,  A61F2/90

Abstract: A docking station includes an expandable frame configured to conform to an interior shape of a blood vessel when expanded inside the blood vessel, wherein the frame includes an annular outer wall formed from at least one annular stent segment connected to a plurality of spring elements circumferentially spaced around the at least one annular stent segment.

公开(公告)号：US20250017726A1

公开(公告)日：2025-01-16

申请号：US18896469

申请日：2024-09-25

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Hanoch Cohen-Tzemach ,  Eran Goldberg

IPC: A61F2/24

Abstract: A prosthetic heart valve including a plurality of leaflets attached to a radially expandable frame is disclosed. The plurality of leaflets is disposed within the frame and configured to regulate a flow of blood through the frame in one direction. Each leaflet is folded along an axially extending fold to form an inner layer and an outer layer. The inner layer of each leaflet is configured to coapt with the inner layers of the other leaflets. A length of the inner layer in a circumferential direction progressively increases upon radial expansion of the frame.

公开(公告)号：US12127960B2

公开(公告)日：2024-10-29

申请号：US17673601

申请日：2022-02-16

Applicant: Edwards Lifesciences Corporation

Inventor： Eran Goldberg ,  Noa Axelrod Manela ,  Yair A. Neumann ,  Boaz Manash ,  David Maimon ,  Eyal Leiba ,  Ralph Schneider ,  Liron Tayeb

IPC: A61F2/966 ,  A61F2/24 ,  A61F2/95 ,  A61M25/00 ,  B29D23/00 ,  A61F2/958 ,  A61F2/962 ,  A61M29/00 ,  B29K105/08

CPC classification number: A61F2/966 ,  A61F2/2436 ,  A61F2/9526 ,  A61M25/0012 ,  A61M25/0023 ,  B29D23/00 ,  A61F2/9517 ,  A61F2/9522 ,  A61F2002/9583 ,  A61F2002/9623 ,  A61F2002/9665 ,  A61F2250/001 ,  A61M2025/0024 ,  A61M25/0045 ,  A61M25/005 ,  A61M25/0074 ,  A61M29/00 ,  A61M2205/0216 ,  B29K2105/0827

Abstract: An expandable sheath is disclosed herein, which has a first polymeric layer and a braided layer positioned radially outward of the first polymeric layer. The braided layer includes a plurality of filaments braided together. The expandable sheaths further include a resilient elastic layer positioned radially outward of the braided layer. The elastic layer is configured to apply radial force to the braided layer and the first polymeric layer. The expandable sheath further includes a second polymeric layer positioned radially outward of the elastic layer and bonded to the first polymeric layer such that the braided layer and the elastic layer are encapsulated between the first and second polymeric layers. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.

公开(公告)号：US12121672B2

公开(公告)日：2024-10-22

申请号：US17078556

申请日：2020-10-23

Applicant: Edwards Lifesciences Corporation

Inventor： Eran Goldberg ,  Liron Tayeb ,  David Maimon

IPC: A61F2/24 ,  A61M25/00 ,  A61F2/962

CPC classification number: A61M25/0023 ,  A61F2/2427 ,  A61F2/962 ,  A61M2025/0024

Abstract: Disclosed herein are reinforced expandable introducer sheaths and methods of using the same. The sheaths minimize trauma to the patient's vasculature by including a reinforcing member to improve the push force of the sheath while reducing the chances of kinking during delivery of a prosthetic device. The sheath can include a plurality of expandable rings aligned along the longitudinal axis of the sheath and coupled together to form an elongated tubular structure. The sheath can also include a plurality of radial members circumferentially arranged to form a tubular support structure. The radial members slidingly interconnected around the circumference of the tubular structure to facilitate radial expansion of the sheath.

公开(公告)号：US20240115382A1

公开(公告)日：2024-04-11

申请号：US18389636

申请日：2023-12-19

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： David Maimon ,  Eran Goldberg ,  Liron Tayeb

IPC: A61F2/24 ,  A61M25/00 ,  A61M25/06

CPC classification number: A61F2/2436 ,  A61M25/0023 ,  A61M25/0662 ,  A61M2025/0024 ,  A61M25/0045 ,  A61M25/005 ,  A61M2205/0216 ,  A61M2205/0266

Abstract: The expandable sheath and methods of use disclosed herein are used to deliver a prosthetic device through a patient's vasculature. The sheath is constructed to be expandable in the circumferential direction, while maintaining sufficient stiffness in the longitudinal direction to withstand pushing and resist kinking. The sheath includes a plurality of curved arms extending outwardly from a longitudinally extending spine. The curved arms move away from the longitudinal axis of the sheath when pushed radially outwardly by a passing prosthetic device, and move back toward the longitudinal axis once the prosthetic device has passed.

公开(公告)号：US11633280B2

公开(公告)日：2023-04-25

申请号：US17359332

申请日：2021-06-25

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Liron Tayeb ,  Eran Goldberg

IPC: A61F2/24 ,  A61M25/00 ,  A61F2/95

Abstract: The active introducer sheath systems disclosed herein are expanded by activating a translation mechanism at the handle. The sheath has an inner cylindrical structure of comingled fixed and mobile elongate rods bound together by an attachment line. Activating the translation mechanism causes the mobile rods to move axially with respect to the fixed rods, changing the internal tension in the attachment line. Increased tension draws the fixed and mobile rods closer together, decreasing the diameter of the cylindrical structure. Decreased tension in the attachment line enables the fixed and mobile rods to move apart, increasing the diameter of the cylindrical structure. A prosthetic device, such as a prosthetic heart valve, can be routed through the expanded sheath and to the implantation site. During implantation, the sheath can be contracted back to its original outer diameter, and expanded again for retrieval of the delivery apparatus.

公开(公告)号：US20220409366A1

公开(公告)日：2022-12-29

申请号：US17901602

申请日：2022-09-01

Applicant: Edwards Lifesciences Corporation

Inventor： Michael Bukin ,  Noam Nir ,  Tamir S. Levi ,  Ziv Yohanan ,  Elena Sherman ,  Eran Goldberg ,  David Maimon

IPC: A61F2/24

Abstract: A prosthetic heart valve and associated methods for assembling a prosthetic heart valve including a plurality of leaflets is disclosed. As one example, a prosthetic heart valve includes a frame; a plurality of commissure support elements, each connected the frame and including two axially-extending members spaced apart from one another to form a window; and a plurality of leaflets, each leaflet comprising a body and two opposing commissure tabs, each commissure tab arranged adjacent to another commissure tab to form a pair of commissure tabs that are disposed in a commissure support element to form a commissure. Each commissure tab includes a series of overlapping layers that include a first set of two overlapping layers that extends through the window and a second set of two overlapping layers that extends away from the first set of two overlapping layers and over an outer side of a corresponding axially-extending member.

公开(公告)号：US11446146B2

公开(公告)日：2022-09-20

申请号：US16784957

申请日：2020-02-07

Applicant: Edwards Lifesciences Corporation

Inventor： Noa Axelrod Manela ,  Oren H. Wintner ,  Eran Goldberg ,  Dikla Kersh ,  Danny M. Garmahi ,  Dan Rottenberg ,  Boaz Manash

IPC: A61F2/24 ,  A61B8/12 ,  A61B17/00 ,  A61B8/08 ,  A61B17/04 ,  A61B8/00

Abstract: Ultrasound probe systems and methods for using an ultrasound probe to assist during treatment of conditions of the human heart are provided. The method may comprise loading a medical instrument into a guide fastened to the ultrasound probe. The ultrasound probe may be inserted into a patient by way of an incision. The distal end of the ultrasound probe may be navigated to a location adjacent to an exterior surface of the heart. A treatment site may be identified on the exterior surface of the heart based on images obtained from an ultrasound transducer disposed within a distal end of the ultrasound probe. The medical instrument may be advanced within the guide to the treatment site and the medical instrument used for treatment. After treatment, the medical instrument may be withdrawn from the treatment site.

公开(公告)号：US20220287851A1

公开(公告)日：2022-09-15

申请号：US17805015

申请日：2022-06-01

Applicant: Edwards Lifesciences Corporation

Inventor： Eran Goldberg ,  Noam Nir

IPC: A61F2/48 ,  A61F2/24 ,  A61B5/00 ,  G16H40/63 ,  H02K7/18 ,  H02K11/00 ,  H02S10/40 ,  H02S40/38

Abstract: A valve monitoring assembly, constituted of: a prosthetic valve, constituted of a frame and leaflets positioned at least partially within the frame, that regulate blood flow through the prosthetic valve; and a monitoring apparatus constituted of: at least one sensor associated with the prosthetic valve, wherein the at least one sensor is selected from the group consisting of: flow sensor, pressure sensor, and temperature sensor; a local control circuitry; at least one communication component configured to wirelessly transmit signals; and an energy harvesting power source, configured to be secured to a patient and comprising a self-powered energy harvesting mechanism and an energy storage member, wherein the energy storage member is configured to store energy generated by the self-powered energy harvesting mechanism, and wherein the energy harvesting power source is configured to supply power to the at least one sensor, the local control circuitry and/or the at least one communication component.