公开(公告)号：US20240307172A1

公开(公告)日：2024-09-19

申请号：US18434642

申请日：2024-02-06

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Michael R. Bialas ,  Kristen Hicks ,  Michael C. Murad ,  Gil Senesh ,  Quang Ngoc Vu ,  Gonzalo German Angelico ,  Carla Susana Cerqueira ,  Victoria Mariko Low ,  Andrea Fernandez ,  Jeanette Jasmine Corona Kelly (formerly Corona) ,  Taylor Michael Winters ,  Ashley Akemi Ishigo ,  Brendan Michael Dalbow ,  Kim D. Nguyen ,  Lien Huong Thi Hoang

IPC: A61F2/24 ,  A61B50/30 ,  A61F2/95 ,  A61F2/958 ,  A61M25/10

CPC classification number: A61F2/24 ,  A61B50/30 ,  A61F2/2418 ,  A61F2/2436 ,  A61M25/10 ,  A61F2/2433 ,  A61F2/9517 ,  A61F2002/9583 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2230/0002 ,  A61F2250/0098

Abstract: Methods and systems for rotationally aligning a commissure of a prosthetic heart valve with a commissure of a native valve are disclosed. In some examples, a method can include advancing a distal end portion of an assembly toward a native heart valve, the assembly comprising a delivery apparatus and a prosthetic heart valve, and including one or more radiopaque markers, where one radiopaque marker is suspended within a cell of a frame of the prosthetic heart valve and aligned with a commissure of the prosthetic heart valve. The method further includes receiving a fluoroscopic image in a selected imaging view of the prosthetic heart valve on the delivery apparatus, determining, based on the fluoroscopic image and the one or more radiopaque markers, whether the prosthetic heart valve is in a desired rotational orientation, and rotating the assembly until the prosthetic heart valve is in the desired rotational orientation.

公开(公告)号：US20240285397A1

公开(公告)日：2024-08-29

申请号：US18656238

申请日：2024-05-06

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Jeanette Jasmine Corona Kelly (formerly Corona) ,  Brendan Michael Dalbow ,  Gil Senesh

IPC: A61F2/24

CPC classification number: A61F2/2415 ,  A61F2/2412 ,  A61F2220/0075

Abstract: Methods and assemblies for attaching leaflets to a frame of a prosthetic heart valve using a connecting skirt are disclosed. As one example, a prosthetic heart valve can include an annular frame comprising a plurality of struts and a valvular structure mounted within the frame and comprising a plurality of leaflets. A cusp edge portion of each leaflet can be connected to the frame by a connecting skirt, where each connecting skirt comprises a central portion and opposing side base portions on opposite sides of the central portion, and each connecting skirt can further comprise side extension portions that extend away from the cusp edge portion of the leaflet and across a portion of cells of the frame that are disposed between cusp edge portions of adjacent leaflets, and covers at least one entire cell of the portion of cells.

公开(公告)号：US11963871B2

公开(公告)日：2024-04-23

申请号：US18080043

申请日：2022-12-13

Applicant: Edwards Lifesciences Corporation

Inventor： Nicholas Brandon Aders ,  Kristen Hicks ,  Gil Senesh ,  Michael R. Bialas ,  Tung T. Le ,  Sean Chow ,  Thanh Huy Le

IPC: B23P11/00 ,  A61F2/24 ,  A61F2/95

CPC classification number: A61F2/2433 ,  B23P11/005 ,  A61F2/9524 ,  A61F2240/001 ,  A61F2250/0039

Abstract: Devices and methods for crimping a prosthetic heart valve onto a delivery device are described. In some embodiments, valves are crimped over an inflatable balloon and between proximal and distal shoulders mounted on a shaft inside the balloon. Crimping methods can include multiple compression steps with the valve located in different axial positions relative to the crimping jaws at each different step. In some methods, the valve may extend partially outside of the crimping jaws during certain crimping steps, such that the crimping force is only applied to the part of the valve that is inside the jaws. Exemplary crimping devices can include two or more adjacent sets of jaws that close down to different inner diameters, such that different parts of a valve get compressed to different outer diameters at the same time during a single crimping step.

公开(公告)号：US20230355383A1

公开(公告)日：2023-11-09

申请号：US18355229

申请日：2023-07-19

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Jeanette Jasmine Corona ,  Brendan Michael Dalbow ,  Gil Senesh

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2220/0075 ,  A61F2230/0019 ,  A61F2230/0023 ,  A61F2240/001

Abstract: Methods and assemblies for attaching leaflets to a frame of a prosthetic heart valve using a connecting skirt are disclosed. As one example, a prosthetic heart valve can include a frame, a valvular structure mounted within the frame and comprising a plurality of leaflets, each leaflet comprising tabs on opposite sides of the leaflet and a cusp edge portion, and a plurality of connecting skirts. Each connecting skirt comprises side base portions and a central portion connected to each of the cusp edge portion of a corresponding leaflet and struts of the frame, each connecting skirt further comprising side extension portions that extend away from the cusp edge portion along a length of the frame, where each side extension portion of each connecting skirt extends across struts of the frame, between cusp edge portions of adjacent leaflets and connects to an adjacent side extension portion of an adjacent connecting skirt.

公开(公告)号：US20230270544A1

公开(公告)日：2023-08-31

申请号：US18311880

申请日：2023-05-03

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Gil Senesh ,  Jeanette Jasmine Corona ,  Sandip Vasant Pawar

IPC: A61F2/24 ,  A61F2/00

CPC classification number: A61F2/2418 ,  A61F2/0077 ,  A61F2210/0076 ,  A61F2250/001

Abstract: A prosthetic heart valve including a frame, leaflet structure, and sealing member disposed around an outer surface of the frame is disclosed. As one example, the sealing member includes a knitted fabric layer, the knitted fabric layer comprising a base layer forming an inner surface of the knitted fabric layer, where the base layer has a mesh-like structure. The knitted fabric layer further comprises a plush outer surface comprising a plurality of pile yarns knit into loops and that extend outward from the base layer.

公开(公告)号：US10583007B2

公开(公告)日：2020-03-10

申请号：US15366959

申请日：2016-12-01

Applicant: Edwards Lifesciences Corporation

Inventor： Arvin T. Chang ,  Yair A. Neumann ,  Gil Senesh ,  Hernan Altman ,  Scott Louis Pool ,  Hannah Gibson ,  Amanda K. Anderson ,  Peter Phong Tran ,  Ly Th Phan

IPC: A61F2/24

Abstract: A delivery apparatus for a prosthetic implant can include an elongate first shaft, a first suture guide coupled to the first shaft, an elongate second shaft, and a second suture guide coupled to the second shaft. The first shaft can extend coaxially through the second shaft and the second suture guide, the first suture guide can be disposed distal to the second suture guide, and the first suture guide and the second suture guide can be configured to be axially movable relative to each other.

公开(公告)号：US20170156859A1

公开(公告)日：2017-06-08

申请号：US15366959

申请日：2016-12-01

Applicant: Edwards Lifesciences Corporation

Inventor： Arvin T. Chang ,  Yair A. Neumann ,  Gil Senesh ,  Hernan Altman ,  Scott Louis Pool ,  Hannah Gibson ,  Amanda K. Anderson ,  Peter Phong Tran ,  Ly Th Phan

IPC: A61F2/24

CPC classification number: A61F2/2439 ,  A61F2/2418 ,  A61F2/2436

Abstract: A delivery apparatus for a prosthetic implant can include an elongate first shaft, a first suture guide coupled to the first shaft, an elongate second shaft, and a second suture guide coupled to the second shaft. The first shaft can extend coaxially through the second shaft and the second suture guide, the first suture guide can be disposed distal to the second suture guide, and the first suture guide and the second suture guide can be configured to be axially movable relative to each other.

公开(公告)号：US20250090311A1

公开(公告)日：2025-03-20

申请号：US18950681

申请日：2024-11-18

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Nikolai Gurovich ,  Gil Senesh ,  Michael Bukin ,  Anatoly Dvorsky ,  Tamir S. Levi ,  Elena Sherman

IPC: A61F2/24 ,  A61F2/00 ,  A61L27/18

Abstract: Outer skirts for a prosthetic heart valve are disclosed. As one example, a prosthetic heart valve can include an annular frame and an outer skirt disposed around an outer surface of the frame. The outer skirt can include a first portion comprising a polymeric material and a second portion comprising a fabric, where the polymeric material has a greater thromboresistance than the fabric. The second portion is secured to an inflow end of the frame and extends toward an intermediate portion of the frame and the first portion extends from the second portion and toward an outflow end of the frame

公开(公告)号：US20250057561A1

公开(公告)日：2025-02-20

申请号：US18940674

申请日：2024-11-07

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Yuval Kasher ,  Gil Senesh ,  Gideon Meyer-Brodnitz ,  Zachary Christopher Berwick ,  Mazen Saadi Albaghdadi ,  Yaeer E. Lev ,  Allen Jeong Keel ,  Atiya Makhdoom Ahmad ,  Matthew Michael Becerra ,  Daniel James Murray

IPC: A61B17/32 ,  A61B17/00 ,  A61B17/3209

Abstract: Disclosed is a medical device comprising an incision assembly coupled to a catheter and an incision opening defined along the incision assembly. A retractable cutting apparatus is disposed within the incision opening and comprises a first incision member comprising at least one first cutting surface and defining a first member proximal end rotatably fixed proximate to a distal end of the incision opening and the at least one cutting surface is located on a bottom edge of the first incision member. A second incision member comprises at least one second cutting surface and defines a second member distal end attached to the first incision member at a connection point between a first member distal end and the first member proximal end of the first incision member, and wherein the at least one second cutting surface is located on a bottom edge of the second incision member.

公开(公告)号：US20240358505A1

公开(公告)日：2024-10-31

申请号：US18769139

申请日：2024-07-10

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Gil Senesh ,  Jeanette Jasmine Corona Kelly (formerly Corona) ,  Sandip Vasant Pawar

IPC: A61F2/24 ,  A61F2/00

CPC classification number: A61F2/2418 ,  A61F2/0077 ,  A61F2210/0076 ,  A61F2250/001

Abstract: A prosthetic heart valve including a frame, leaflet structure, and sealing member disposed around an outer surface of the frame is disclosed. An inflow end of the frame is defined by a plurality of spaced apart inflow apices. As one example, the sealing member has a circumferentially extending inflow edge and a circumferentially extending outflow edge, where the inflow edge is attached to the plurality of inflow apices, and where the inflow edge has an undulating shape around a circumference of the frame.