公开(公告)号：US5419865A

公开(公告)日：1995-05-30

申请号：US241670

申请日：1994-05-12

申请人： Eiji Ogata ,  Shokichi Seki

发明人： Eiji Ogata ,  Shokichi Seki

IPC分类号： B29C33/10 ,  B29C33/42 ,  B29C45/26 ,  B29C45/34 ,  B29C45/37 ,  B29C45/56 ,  B29D99/00 ,  B29L31/34 ,  H04R1/02 ,  B29C39/36

CPC分类号： H04R1/023 ,  B29C45/2628

摘要： A method of making plastic molding consists of a boxlike body having an field of multiple fine conical holes. The internal diameter of the fine conical holes gradually decreases from the inner surface of the plastic molding toward the outer surface of the plastic molding, and is in the range 0.1-0.5 mm at the outer surface. The fine conical holes are hardly visible when the outer surface of the box is viewed; ventilation is provided without detriment to the aesthetic appearance of the exterior of the box, and it is not necessary to cover the ventilation holes in the box to keep them out of sight. Conical projection on a male mold are withdrawn before the plastic molding hardens completely and the male mold is separated from a female mold after the plastic material has hardened completely.

摘要翻译： 制造塑料成型的方法由具有多个细圆锥孔的场的盒状体构成。 细圆锥孔的内径从塑料模制品的内表面朝向塑料模制件的外表面逐渐减小，并且在外表面处于0.1-0.5mm的范围内。 当观察箱的外表面时，细小的锥形孔几乎看不到; 提供通风而不损害箱体外观的美观外观，并且不需要覆盖盒中的通风孔以使其不在视线之内。 在塑料模制完全硬化之前，取出阳模上的锥形突出物，并且在塑料材料完全硬化后，阳模与阴模分离。

公开(公告)号：US20120223892A1

公开(公告)日：2012-09-06

申请号：US13039899

申请日：2011-03-03

申请人： Masaki Matsubara ,  Eiji Ogata

发明人： Masaki Matsubara ,  Eiji Ogata

IPC分类号： G06F3/041

CPC分类号： G06F3/0488 ,  G06F1/1626

摘要： A display device for displaying information thereon, comprising a display unit adapted to display information in a plurality of display orientations, an orientation determination unit adapted to determine a physical orientation of the display device, a touch sensor adapted to sense a touch input from a user, and a display controller adapted to rotate the information displayed by the display unit from a first display orientation to a second display orientation when the orientation determination unit determines a change in the physical orientation, wherein the display controller suspends rotation of the information displayed by the display unit in the first orientation when the touch sensor senses a touch input substantially contemporaneously with when the orientation determination unit determines the change in the physical orientation.

摘要翻译： 一种用于在其上显示信息的显示装置，包括适于以多个显示方向显示信息的显示单元，适于确定显示装置的物理定向的方向确定单元，适于感测来自用户的触摸输入的触摸传感器 以及显示控制器，其适于在所述姿势确定单元确定所述物理姿势的变化时将所述显示单元显示的信息从第一显示方向旋转到第二显示方向，其中所述显示控制器暂停所述显示控制信息显示的信息的旋转 当触摸传感器与取向确定单元确定物理定向的变化时基本同时地感测触摸输入时，以第一方位显示单元。

公开(公告)号：US07456321B2

公开(公告)日：2008-11-25

申请号：US10529074

申请日：2003-09-22

申请人： Eiji Ogata ,  Fumio Oi ,  Norio Yanase ,  Nobuyuki Nate

发明人： Eiji Ogata ,  Fumio Oi ,  Norio Yanase ,  Nobuyuki Nate

IPC分类号： C07F315/00

CPC分类号： C07C315/00 ,  C07C315/06 ,  C07C317/22

摘要： The present invention provides a process for producing 4,4′-dihydroxydiphenylsulfone of very high purity. In particular, the present invention provides a process for producing 4,4′-dihydroxydiphenylsulfone of high purity comprising the steps of subjecting phenol in combination with a sulfonating agent or phenolsulfonic acid to a dehydration reaction in the presence of an aromatic nonpolar solvent while suspending the resulting dihydroxydiphenylsulfone therein, mixing the reaction suspension with a polar solvent to at least partially dissolve the dihydroxydiphenylsulfone, and precipitating 4,4′-dihydroxydiphenylsulfone.

摘要翻译： 本发明提供了一种制备非常高纯度的4,4'-二羟基二苯砜的方法。 特别地，本发明提供了一种制备高纯度的4,4'-二羟基二苯基砜的方法，包括以下步骤：在芳族非极性溶剂的存在下使苯酚与磺化剂或苯酚磺酸组合进行脱水反应，同时使 将反应悬浮液与极性溶剂混合至少部分溶解二羟基二苯基砜，并沉淀出4,4'-二羟基二苯基砜。

公开(公告)号：US5241121A

公开(公告)日：1993-08-31

申请号：US904887

申请日：1992-06-25

申请人： Eiji Ogata ,  Nobuyuki Nate ,  Kazuo Hamano

发明人： Eiji Ogata ,  Nobuyuki Nate ,  Kazuo Hamano

IPC分类号： C07C315/00 ,  C07C315/04 ,  C07C317/22

CPC分类号： C07C315/00 ,  C07C315/04

摘要： A process for preparing 4,4'-dihydroxydiphenylsulfone, the process including heating 4,4'-dihydroxydiphenylsulfone and 2,4'-dihydroxydiphenylsulfone in the presence of an acid catalyst to isomerize the 2,4'-dihydroxydiphenylsulfone into 4,4'-dihydroxydiphenylsulfone, the process being characterized in that a suspension of 4,4'-dihydroxydiphenylsulfone and 2,4'-dihydroxydiphenylsulfone in a liquid dispersing medium is heated for isomerization while the liquid portion is distilled off or a crystal mixture of 4,4'-dihydroxydiphenylsulfone and 2,4'-dihydroxydiphenylsulfone is heated for isomerization to produce 4,4'-dihydroxydiphenylsulfone in the form of crystal powder.

摘要翻译： 一种制备4,4'-二羟基二苯砜的方法，该方法包括在酸催化剂存在下加热4,4'-二羟基二苯砜和2,4'-二羟基二苯砜，使2,4'-二羟基二苯砜异构化成4,4'-二羟基二苯砜， 二氢二苯基砜，其特征在于将4,4'-二羟基二苯基砜和2,4'-二羟基二苯基砜在液体分散介质中的悬浮液加热异构化，同时蒸馏掉液体部分或4,4'-二羟基二苯基砜的结晶混合物， 二羟基二苯砜和2,4'-二羟基二苯砜加热异构化，生成结晶粉末形式的4,4'-二羟基二苯砜。

公开(公告)号：US4162270A

公开(公告)日：1979-07-24

申请号：US896611

申请日：1978-04-14

申请人： Eiji Ogata ,  Koji Ono ,  Shoji Nakagaki

发明人： Eiji Ogata ,  Koji Ono ,  Shoji Nakagaki

IPC分类号： C07C315/00 ,  C07C317/22 ,  C07C147/10

CPC分类号： C07C315/00

摘要： In a process for producing 4,4'-dihydroxydiphenylsulfone by reacting phenol with sulfuric acid in the presence of a solvent, an improvement which comprises using at least a member selected from the group consisting of chlorobenzene, dichlorobenzene, trichlorobenzene, chlorotoluene, diethylbenzene, xylene, decalin, tetralin and tetrachloroethane as the solvent and removing said solvent progressively and finally substantially completely from the mixture while maintaining the reaction mixture at a temperature of about 160.degree. to about 200.degree. C. to effect precipitation of 4,4'-dihydroxydiphenylsulfone and isomerization of 2,4'-dihydroxydiphenylsulfone to 4,4'-dihydroxydiphenylsulfone.

摘要翻译： 在溶剂存在下，通过苯酚与硫酸反应生产4,4'-二羟基二苯砜的方法，包括使用至少一种选自氯苯，二氯苯，三氯苯，氯甲苯，二乙苯，二甲苯 ，十氢化萘，四氢化萘和四氯乙烷作为溶剂，并逐渐地并最终基本上完全从混合物中除去所述溶剂，同时将反应混合物保持在约160℃至约200℃的温度，以实现4,4'-二羟基二苯砜和 2,4'-二羟基二苯砜异构化为4,4'-二羟基二苯砜。

公开(公告)号：US20050272956A1

公开(公告)日：2005-12-08

申请号：US10529074

申请日：2003-09-22

申请人： Eiji Ogata ,  Fumio Oi ,  Norio Yanase ,  Nobuyuki Nate

发明人： Eiji Ogata ,  Fumio Oi ,  Norio Yanase ,  Nobuyuki Nate

IPC分类号： C07C315/00 ,  C07C315/06 ,  C07C317/22

CPC分类号： C07C315/00 ,  C07C315/06 ,  C07C317/22

摘要： The present invention provides a process for producing 4,4′-dihydroxydiphenylsulfone of very high purity. In particular, the present invention provides a process for producing 4,4′-dihydroxydiphenylsulfone of high purity comprising the steps of subjecting phenol in combination with a sulfonating agent or phenolsulfonic acid to a dehydration reaction in the presence of an aromatic nonpolar solvent while suspending the resulting dihydroxydiphenylsulfone therein, mixing the reaction suspension with a polar solvent to at least partially dissolve the dihydroxydiphenylsulfone, and precipitating 4,4′-dihydroxydiphenylsulfone.

摘要翻译： 本发明提供了一种制备非常高纯度的4,4'-二羟基二苯砜的方法。 特别地，本发明提供了一种制备高纯度的4,4'-二羟基二苯基砜的方法，包括以下步骤：在芳族非极性溶剂的存在下使苯酚与磺化剂或苯酚磺酸组合进行脱水反应，同时使 将反应悬浮液与极性溶剂混合至少部分溶解二羟基二苯基砜，并沉淀出4,4'-二羟基二苯基砜。

公开(公告)号：US06299912B1

公开(公告)日：2001-10-09

申请号：US09556460

申请日：2000-04-24

申请人： Shinobu Ito ,  Kuniaki Shimbo ,  Eiji Ogata

发明人： Shinobu Ito ,  Kuniaki Shimbo ,  Eiji Ogata

IPC分类号： A23K100

CPC分类号： A23K50/80 ,  A23K20/174 ,  A23K20/189 ,  A23K50/00 ,  A23K50/10 ,  A23K50/40 ,  A23K50/75 ,  Y10S426/805 ,  Y10S426/807

摘要： A preparation for administration to animals, comprising a sparingly soluble L-ascorbic acid-2-phosphoric ester salt having a solubility in water of 10 wt % or less, the solubility being a value obtained by placing 100 g of purified water in a 200 ml-volume beaker, stirring the water while keeping the temperature at 20° C., adding 0.1 g of the L-ascorbic acid-2-phosphoric ester salt every 5 minutes by taking care not to cause gelation, and 30 minutes after the addition of L-ascorbic acid-2-phosphoric ester salt when the undissolved L-ascorbic acid-2-phosphoric ester salt is observed visually in the aqueous solution, determining the amount in weight percentage of L-ascorbic acid-2-phosphoric ester salt added based on water, and a method for feeding animals, using the preparation.

摘要翻译： 一种用于给予动物的制剂，其包含在水中的溶解度为10重量％以下的微溶L-抗坏血酸-2-磷酸酯盐，其溶解度为将100g纯化水放入200ml 在保持温度为20℃的同时搅拌水，每5分钟加入0.1g L-抗坏血酸-2-磷酸酯盐，注意不引起凝胶化，加入后30分钟 在水溶液中观察未溶解的L-抗坏血酸-2-磷酸酯盐时，测定L-抗坏血酸-2-磷酸酯盐的重量百分比量 在水上，以及饲养动物的方法。

公开(公告)号：US5965750A

公开(公告)日：1999-10-12

申请号：US849052

申请日：1997-05-29

申请人： Yutaka Oonishi ,  Tsutomu Nozawa ,  Takami Ooe ,  Keisuke Mano ,  Naoaki Misu ,  Yohei Kurata ,  Shinobu Ito ,  Eiji Ogata

发明人： Yutaka Oonishi ,  Tsutomu Nozawa ,  Takami Ooe ,  Keisuke Mano ,  Naoaki Misu ,  Yohei Kurata ,  Shinobu Ito ,  Eiji Ogata

IPC分类号： A61K8/02 ,  A61K8/67 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q5/02 ,  A61Q7/00 ,  A61Q11/00 ,  A61Q19/00 ,  A61Q19/10 ,  C07F9/655 ,  G01N30/02 ,  G01N30/88 ,  G01N33/82 ,  C07F9/06

CPC分类号： G01N33/82 ,  A61K8/0212 ,  A61K8/678 ,  A61Q19/00 ,  C07F9/65522 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q11/00 ,  A61Q19/10 ,  A61Q5/02 ,  A61Q7/00 ,  G01N2030/884 ,  G01N30/02 ,  Y10S514/846

摘要： Disclosed herein are a highly purified tocopheryl phosphate and/or a salt thereof (tocopheryl phosphates) wherein a P,P'-bistocopheryl hypophosphate and/or a salt thereof (P,P'-bistocopheryl diphoshates) is contained in a proportion of not higher than 3% by weight; a process for producing a highly purified tocopheryl phosphate and/or a salt thereof, which comprises the steps of reacting a tocopherol with an oxyphosphorus trihalide followed by treating with an acid or basic aqueous solution to thereby form tocopheryl phosphates (i) in which P,P'-bistocopheryl diphoshates (ii) formed as by-products are contained, hydrolyzing the P,P'-bistocopheryl diphoshates (ii) under acid condition, and, optionally, rendering the hydrolyzate neutral or basic under basic condition; and a method of analyzing tocopheryl phosphates, comprising analyzing a sample containing components (i) and (ii) with the use of a high-performance liquid chromatograph column packed with a gel of a polymethacrylate having, bonded thereto, long-chain alkyl groups. None or only an extremely minute amount of P,P'-bistocopheryl diphoshates are contained in the highly purified tocopheryl phosphates, so that the highly purified tocopheryl phosphates exhibit antioxidant and blood circulation promoting effects, have excellent water solubility, are powdery so that the handling thereof is extremely easy, are free from cutaneous irritation and allergenecity and ensure dermal safety. Therefore, the highly purified tocopheryl phosphates are useful as cosmetic ingredients. The amounts of components (i) and (ii) can be simply measured with high accuracy by the above method.

公开(公告)号：US5937790A

公开(公告)日：1999-08-17

申请号：US993714

申请日：1997-12-18

申请人： Shinobu Ito ,  Eiji Ogata ,  Masahiro Yamada

发明人： Shinobu Ito ,  Eiji Ogata ,  Masahiro Yamada

IPC分类号： A61K31/70 ,  A01K29/00 ,  A23K1/165 ,  A23K1/17

CPC分类号： A61K31/70

摘要： An anti-stress agent for animals for reducing the growth inhibition or mortality of animals and a method of reducing stress using a feed composition having blended therein the anti-stress agent. The anti-stress agent for animals comprises one or more substances selected from L-ascorbic acid-2-phosphoric acid, a salt thereof and an L-ascorbic acid-2-glucoside, as an active ingredient, for inhibiting the increase of blood plasma lactate dehydrogenase (LDH), malate dehydrogenase (MDH) and aspartate aminotransferase (AspAT) and for inhibiting the increase of stress proteins in blood, which occur when animals are placed under stress. Also disclosed is a feed composition comprising the anti-stress agent, and a method of reducing the stress of animals by supplying the same as feed.

摘要翻译： 用于降低动物的生长抑制或死亡率的动物的抗应激剂和使用其中混合有抗应激剂的饲料组合物来降低应激的方法。 用于动物的抗应激剂包含选自L-抗坏血酸-2-磷酸，其盐和L-抗坏血酸-2-葡萄糖苷作为活性成分的一种或多种物质，用于抑制血浆中的增加 乳酸脱氢酶（LDH），苹果酸脱氢酶（MDH）和天冬氨酸氨基转移酶（AspAT），并用于抑制动物在压力下发生的血液中应激蛋白的增加。 还公开了包含抗应激剂的饲料组合物，以及通过将饲料作为饲料供应来减少动物的压力的方法。

公开(公告)号：US5596128A

公开(公告)日：1997-01-21

申请号：US300844

申请日：1994-09-06

申请人： Eiji Ogata ,  Norio Yanase ,  Takayuki Kitahara

发明人： Eiji Ogata ,  Norio Yanase ,  Takayuki Kitahara

IPC分类号： C07B45/02 ,  C07C303/04 ,  C07C309/30 ,  C07C309/35 ,  C07C309/43 ,  C07C309/45 ,  C07C309/46 ,  C07C309/50 ,  C08F8/36 ,  C07C303/02

CPC分类号： C07C303/04 ,  C07B45/02 ,  C08F8/34 ,  C07C2103/24

摘要： A sulfonating agent represented by the general formula ##STR1## wherein the groups R.sup.1 are the same or different and are each a lower alkyl group having 1 to 3 carbon atoms, n is an integer of 3, 4 or 5, m is an integer of 1 or 2, and n+m.ltoreq.6, and a process for sulfonating an aromatic compound with use of the sulfonating agent.

摘要翻译： 由通式表示的磺化剂，其中基团R 1相同或不同，并且各自是具有1至3个碳原子的低级烷基，n是3,4或5的整数，m是 1或2，n + m 6，以及使用磺化剂磺化芳族化合物的方法。