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公开(公告)号:US20240252413A1
公开(公告)日:2024-08-01
申请号:US18503064
申请日:2023-11-06
Applicant: Evolved by Nature, Inc.
Inventor: Gregory H. Altman , Rebecca L. Lacouture , Rachel Lee Dow , Rachel M. Lind , Dylan S. Haas
IPC: A61K8/64 , A45D33/00 , A61K8/02 , A61K8/04 , A61K8/19 , A61K8/27 , A61K8/29 , A61K8/365 , A61K8/49 , A61K8/67 , A61K8/73 , A61K8/92 , A61K8/97 , A61K8/9789 , A61K8/9794 , A61K8/98 , A61K9/08 , A61K31/375 , A61K38/00 , A61K38/01 , A61K45/06 , A61K47/02 , A61K47/12 , A61K47/36 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , C07K1/12 , C07K14/435
CPC classification number: A61K8/64 , A45D33/00 , A61K8/02 , A61K8/0216 , A61K8/042 , A61K8/19 , A61K8/27 , A61K8/29 , A61K8/365 , A61K8/4953 , A61K8/676 , A61K8/735 , A61K8/922 , A61K8/97 , A61K8/9789 , A61K8/9794 , A61K8/987 , A61K9/08 , A61K31/375 , A61K38/00 , A61K38/012 , A61K45/06 , A61K47/02 , A61K47/12 , A61K47/36 , A61Q17/04 , A61Q19/00 , A61Q19/007 , A61Q19/02 , A61Q19/08 , C07K1/12 , C07K14/43586 , A61K2800/591 , A61K2800/72 , A61K2800/74 , A61K2800/75
Abstract: A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.
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公开(公告)号:US20240189204A1
公开(公告)日:2024-06-13
申请号:US18336431
申请日:2023-06-16
Applicant: Evolved By Nature, Inc.
Inventor: Gregory H. Altman , Dylan S. Haas , Kevin T. Healy
IPC: A61K8/64 , A61K8/04 , A61K8/06 , A61K8/19 , A61K8/20 , A61K8/27 , A61K8/29 , A61K8/36 , A61K8/365 , A61K8/368 , A61K8/37 , A61K8/49 , A61K8/67 , A61K8/73 , A61K8/92 , A61K8/9789 , A61Q1/04 , A61Q1/06 , A61Q5/02 , A61Q5/12 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61Q19/10
CPC classification number: A61K8/64 , A61K8/042 , A61K8/062 , A61K8/064 , A61K8/19 , A61K8/20 , A61K8/27 , A61K8/29 , A61K8/361 , A61K8/365 , A61K8/368 , A61K8/37 , A61K8/4953 , A61K8/676 , A61K8/678 , A61K8/735 , A61K8/922 , A61K8/9789 , A61Q1/04 , A61Q5/02 , A61Q5/12 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61Q19/007 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61K2800/10 , A61K2800/28 , A61K2800/30 , A61K2800/805 , A61Q1/06
Abstract: In an embodiment, a moisturizing composition includes a silk solution, wherein the silk solution comprises about 1% to about 10% (w/v) of pure silk fibroin-based protein fragments that are substantially devoid of sericin; hyaluronic acid; an oil or butter; and a pH adjusting agent.
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公开(公告)号:US20240141583A1
公开(公告)日:2024-05-02
申请号:US18550922
申请日:2022-03-16
Applicant: EVOLVED BY NATURE, INC.
Inventor: Xiuzhu Fei , Enrico Mortarino , Gregory H. Altman , Laura Muollo , Murat Tonga , Joshua Davis
IPC: D06M15/15
CPC classification number: D06M15/15
Abstract: The disclosure provides novel silk fibroin coated articles and methods of preparing same.
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公开(公告)号:US11878070B2
公开(公告)日:2024-01-23
申请号:US15570653
申请日:2016-04-29
Applicant: Evolved By Nature, Inc.
Inventor: Gregory H. Altman , Dylan S. Haas , Kevin T. Healy
IPC: A61K8/64 , A61K8/04 , A61K8/06 , A61K8/19 , A61K8/20 , A61K8/27 , A61K8/29 , A61K8/36 , A61K8/365 , A61K8/368 , A61K8/37 , A61K8/49 , A61K8/67 , A61Q5/02 , A61Q5/12 , A61Q15/00 , A61K8/73 , A61Q17/04 , A61K8/92 , A61Q19/00 , A61K8/9789 , A61Q1/04 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61Q1/06
CPC classification number: A61K8/64 , A61K8/042 , A61K8/062 , A61K8/064 , A61K8/19 , A61K8/20 , A61K8/27 , A61K8/29 , A61K8/361 , A61K8/365 , A61K8/368 , A61K8/37 , A61K8/4953 , A61K8/676 , A61K8/678 , A61K8/735 , A61K8/922 , A61K8/9789 , A61Q1/04 , A61Q5/02 , A61Q5/12 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61Q19/007 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61K2800/10 , A61K2800/28 , A61K2800/30 , A61K2800/805 , A61Q1/06
Abstract: In an embodiment, a moisturizing composition includes a silk solution, wherein the silk solution comprises about 1% to about 10% (w/v) of pure silk fibroin-based protein fragments that are substantially devoid of sericin; hyaluronic acid; an oil or butter; and a pH adjusting agent.
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公开(公告)号:US20240016145A1
公开(公告)日:2024-01-18
申请号:US17857753
申请日:2022-07-05
Applicant: Evolved by Nature, Inc.
Inventor: Gregory H. Altman , Carlos J. Bosques , Abigail Giarrosso
Abstract: The disclosure provides a coated seed and methods of making the coated seed, wherein the coating comprises silk fibroin fragments. In an embodiment, the coating further comprises a plant growth regulator. The disclosure further provides formulations comprising silk fibroin fragments and a plant growth regulator.
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公开(公告)号:US11857664B2
公开(公告)日:2024-01-02
申请号:US17716743
申请日:2022-04-08
Applicant: Evolved By Nature, Inc.
Inventor: Gregory H. Altman , Rebecca L. Lacouture , Rachel Lee Dow , Rachel M. Lind , Dylan S. Haas
IPC: A61K9/08 , A61K8/02 , A61K38/01 , A61K8/64 , C07K1/12 , C07K14/435 , A61K38/00 , A61K8/98 , A61Q19/02 , A61K8/92 , A61K8/04 , A61K8/19 , A61K8/9789 , A61K8/9794 , A61K8/97 , A61K31/375 , A61K45/06 , A61K47/02 , A61K47/12 , A61K47/36 , A61K8/27 , A61K8/29 , A61K8/67 , A61K8/73 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A45D33/00 , A61K8/365 , A61K8/49
CPC classification number: A61K8/64 , A45D33/00 , A61K8/02 , A61K8/0216 , A61K8/042 , A61K8/19 , A61K8/27 , A61K8/29 , A61K8/365 , A61K8/4953 , A61K8/676 , A61K8/735 , A61K8/922 , A61K8/97 , A61K8/9789 , A61K8/9794 , A61K8/987 , A61K9/08 , A61K31/375 , A61K38/00 , A61K38/012 , A61K45/06 , A61K47/02 , A61K47/12 , A61K47/36 , A61Q17/04 , A61Q19/00 , A61Q19/007 , A61Q19/02 , A61Q19/08 , C07K1/12 , C07K14/43586 , A61K2800/591 , A61K2800/72 , A61K2800/74 , A61K2800/75
Abstract: A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.
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公开(公告)号:US11298311B2
公开(公告)日:2022-04-12
申请号:US16795921
申请日:2020-02-20
Applicant: Evolved by Nature, Inc.
Inventor: Gregory H. Altman , Rebecca L. Lacouture , Rachel Lee Dow , Rachel M. Lind , Dylan S. Haas
IPC: A61K9/08 , A61K8/02 , A61K38/01 , A61K8/64 , C07K1/12 , C07K14/435 , A61K38/00 , A61K8/98 , A61Q19/02 , A61K8/92 , A61K8/04 , A61K8/19 , A61K8/9789 , A61K8/9794 , A61K8/97 , A61K8/27 , A61K8/29 , A61K8/67 , A61K8/73 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A45D33/00 , A61K8/365 , A61K8/49
Abstract: A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.
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公开(公告)号:US20190380944A1
公开(公告)日:2019-12-19
申请号:US16453597
申请日:2019-06-26
Applicant: Evolved by Nature, Inc.
Inventor: Gregory H. Altman , Rebecca L. Lacouture , Rachel Lee Dow , Rachel M. Lind , Dylan S. Haas
IPC: A61K8/64 , C07K1/12 , C07K14/435 , A61K9/08 , A61K38/00 , A61K38/01 , A61K8/98 , A61Q19/02 , A61K8/92 , A61K8/04 , A61K8/19 , A61K8/02 , A61K8/27 , A61K8/29 , A61K8/67 , A61K8/73 , A61K8/97 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A45D33/00 , A61K8/365 , A61K8/49
Abstract: A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.
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公开(公告)号:US12227897B2
公开(公告)日:2025-02-18
申请号:US18179869
申请日:2023-03-07
Applicant: Evolved by Nature, Inc.
Inventor: Gregory H. Altman , Enrico Mortarino
Abstract: Silk performance apparel and methods of preparing the same are disclosed herein. In some embodiments, silk performance apparel includes textiles, fabrics, consumer products, and other materials that are coated with aqueous solutions of pure silk fibroin-based protein fragments. In some embodiments, coated apparel products exhibit surprisingly improved moisture management properties and increased resistance to microbial growth.
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30.
公开(公告)号:US20240408174A1
公开(公告)日:2024-12-12
申请号:US18702304
申请日:2022-10-18
Applicant: EVOLVED BY NATURE, INC.
Inventor: Gregory H. Altman , MARIUS COSTACHE , EVA GENEL , CARLOS J. BOSQUES , JUTAMAS SUWANPRADID , AVINASH JAIGANESH , LAURA R. MUOLLO
Abstract: The disclosure provides silk fibroin compositions for stimulating collagen expression, claudin-1, and-or an anti-inflammatory effect in a subject, and methods of use thereof.
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