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公开(公告)号:US11660372B2
公开(公告)日:2023-05-30
申请号:US17592312
申请日:2022-02-03
Applicant: EVOLVED BY NATURE, INC.
Inventor: Gregory H. Altman , Peng Xu , Erlei Jin
CPC classification number: A61L27/26 , A61L27/52 , A61L2300/402 , A61L2400/06 , A61L2430/34
Abstract: Hyaluronic acid and silk protein fragments based tissue fillers and methods of using the same are provided herein.
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公开(公告)号:US20220226223A1
公开(公告)日:2022-07-21
申请号:US17716743
申请日:2022-04-08
Applicant: Evolved By Nature, Inc.
Inventor: Gregory H. Altman , Rebecca L. Lacouture , Rachel Lee Dow , Rachel M. Lind , Dylan S. Haas
IPC: A61K8/64 , C07K1/12 , C07K14/435 , A61K9/08 , A61K38/00 , A61K38/01 , A61K8/98 , A61Q19/02 , A61K8/92 , A61K8/04 , A61K8/19 , A61K8/9789 , A61K8/9794 , A61K8/97 , A61K8/02 , A61K8/27 , A61K8/29 , A61K8/67 , A61K8/73 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A45D33/00 , A61K8/365 , A61K8/49
Abstract: A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.
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公开(公告)号:US20220127781A1
公开(公告)日:2022-04-28
申请号:US17260336
申请日:2019-07-18
Applicant: EVOLVED BY NATURE, INC.
Inventor: Gregory H. ALTMAN , Carlos J. BOSQUES , Alexander J. WOLFE , Sara A. JOHNSON , Enrico MORTARINO , Maria L. UFRET , Sanghamitra SEN
Abstract: Silk processed, coated, repaired, and/or infused leather or leather articles, and methods of preparing the same are disclosed herein. In some embodiments, the invention relates to silk-coated leather apparel and products for use in home and automotive applications, such as leather coated with pure silk fibroin-based proteins or protein fragments thereof. In some embodiments, the invention relates to silk and silk protein fragments compositions, and methods of making and using thereof, for processing leather, for example coating leather, and/or repairing, hiding, or masking defects on or within leather, and/or as a mixing agent, additive, or replacement for leather processing chemicals.
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公开(公告)号:US11298310B2
公开(公告)日:2022-04-12
申请号:US16795488
申请日:2020-02-19
Applicant: Evolved By Nature, Inc.
Inventor: Gregory H. Altman , Rebecca L. Lacouture , Rachel Lee Dow , Rachel M. Lind , Dylan S. Haas
IPC: A61K9/08 , A61K8/02 , A61K38/01 , A61K8/64 , C07K1/12 , C07K14/435 , A61K38/00 , A61K8/98 , A61Q19/02 , A61K8/92 , A61K8/04 , A61K8/19 , A61K8/9789 , A61K8/9794 , A61K8/97 , A61K8/27 , A61K8/29 , A61K8/67 , A61K8/73 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A45D33/00 , A61K8/365 , A61K8/49
Abstract: A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.
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公开(公告)号:US11260012B2
公开(公告)日:2022-03-01
申请号:US15543029
申请日:2016-01-12
Applicant: Evolved By Nature, Inc.
Inventor: Gregory H. Altman , Dylan S. Haas , Rebecca L. Lacouture
IPC: A61Q19/02 , A61Q17/04 , A61K47/42 , A61K47/22 , A61K31/522 , A61K9/70 , A61K9/00 , A61K8/92 , A61K8/67 , A61K8/368 , A61Q19/08 , A61K8/04 , A61K8/64 , A61K8/365 , A61K8/49 , A61Q19/00 , A61Q17/00 , A61K8/02 , C07K14/435 , A61K8/9789
Abstract: In some embodiments, a composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals. In some embodiments, a composition is disclosed that includes silk fibroin-based protein fragments and is suitable for use in consumer applications. In some embodiments, a preserved composition is disclosed that includes silk fibroin-based protein fragments. In some embodiments, a method of preserving a solution using silk fibroin-based protein fragments is disclosed.
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公开(公告)号:US20190211498A1
公开(公告)日:2019-07-11
申请号:US16356550
申请日:2019-03-18
Applicant: Evolved by Nature, Inc.
Inventor: Gregory H. Altman , Enrico Mortarino
CPC classification number: D06M15/15 , A41D13/0015 , A41D31/00 , A61K8/64 , A61Q19/00 , D06M2200/50 , D06N7/00 , D06N2203/02 , D10B2401/02
Abstract: Silk performance apparel and methods of preparing the same are disclosed herein. In some embodiments, silk performance apparel includes textiles, fabrics, consumer products, and other materials that are coated with aqueous solutions of pure silk fibroin-based protein fragments. In some embodiments, coated apparel products exhibit surprisingly improved moisture management properties and increased resistance to microbial growth.
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公开(公告)号:US11970815B2
公开(公告)日:2024-04-30
申请号:US17628471
申请日:2020-07-18
Applicant: EVOLVED BY NATURE, INC.
Inventor: Gregory H. Altman , Carlos J. Bosques , Enrico Mortarino
CPC classification number: D06N3/126 , D06N3/128 , D06N3/14 , D06N2201/042 , D06N2201/06 , D06N2211/28
Abstract: Silk processed, coated, repaired, and/or infused faux or bonded leather, or faux or bonded leather articles, and methods of preparing the same are disclosed herein.
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公开(公告)号:US20230416978A1
公开(公告)日:2023-12-28
申请号:US17732107
申请日:2022-04-28
Applicant: EVOLVED BY NATURE, INC.
Inventor: Gregory H. Altman , Enrico Mortarino , Sara Ann Johnson , Maria L. Ufret , Markrete Krikorian , Rebecca L. Lacouture
IPC: D06M15/15 , C09D189/00 , D06M15/643 , D06P5/08
CPC classification number: D06M15/15 , C09D189/00 , D06M15/643 , D06P5/08 , D06M2101/12
Abstract: Silk coated and/or infused performance materials, apparel, and methods of preparing the same are disclosed herein. In some embodiments, silk performance apparel includes textiles, fabrics, consumer products, and other materials that are coated with aqueous solutions of pure silk fibroin-based protein fragments having low, medium, and/or high molecular weight in various ratios.
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公开(公告)号:US20230220614A1
公开(公告)日:2023-07-13
申请号:US18179869
申请日:2023-03-07
Applicant: Evolved by Nature, Inc.
Inventor: Gregory H. Altman , Enrico Mortarino
CPC classification number: D06M15/15 , D06N7/00 , A61K8/64 , A41D31/185 , A41D31/00 , A41D13/0015 , A61Q19/00 , D06N2203/02 , D10B2401/02 , D06M2200/50
Abstract: Silk performance apparel and methods of preparing the same are disclosed herein. In some embodiments, silk performance apparel includes textiles, fabrics, consumer products, and other materials that are coated with aqueous solutions of pure silk fibroin-based protein fragments. In some embodiments, coated apparel products exhibit surprisingly improved moisture management properties and increased resistance to microbial growth.
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公开(公告)号:US20230212234A1
公开(公告)日:2023-07-06
申请号:US17861936
申请日:2022-07-11
Applicant: Evolved by Nature, Inc.
Inventor: Gregory H. Altman , Rebecca L. Lacouture , Rachel Lee Dow , Rachel M. Lind , Dylan S. Haas
IPC: C07K14/435 , A61K31/375 , A61K45/06 , A61K47/12 , A61K47/36 , A61K47/02
CPC classification number: C07K14/43586 , A61K31/375 , A61K45/06 , A61K47/12 , A61K47/36 , A61K47/02
Abstract: A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.
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