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公开(公告)号:US20230212234A1
公开(公告)日:2023-07-06
申请号:US17861936
申请日:2022-07-11
Applicant: Evolved by Nature, Inc.
Inventor: Gregory H. Altman , Rebecca L. Lacouture , Rachel Lee Dow , Rachel M. Lind , Dylan S. Haas
IPC: C07K14/435 , A61K31/375 , A61K45/06 , A61K47/12 , A61K47/36 , A61K47/02
CPC classification number: C07K14/43586 , A61K31/375 , A61K45/06 , A61K47/12 , A61K47/36 , A61K47/02
Abstract: A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.
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公开(公告)号:US20220133615A1
公开(公告)日:2022-05-05
申请号:US17576404
申请日:2022-01-14
Applicant: EVOLVED BY NATURE, INC.
Inventor: Gregory H. Altman , Dylan S. Haas , Rebecca L. Lacouture
IPC: A61K8/64 , A61K8/368 , A61K8/67 , A61K8/92 , A61K8/04 , A61K8/365 , A61K8/49 , A61Q19/00 , A61Q17/00 , A61K8/02 , C07K14/435 , A61K8/9789 , A61K9/00 , A61K9/70 , A61K31/522 , A61K47/22 , A61K47/42 , A61Q17/04 , A61Q19/02 , A61Q19/08
Abstract: In some embodiments, a composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals. In some embodiments, a composition is disclosed that includes silk fibroin-based protein fragments and is suitable for use in consumer applications. In some embodiments, a preserved composition is disclosed that includes silk fibroin-based protein fragments. In some embodiments, a method of preserving a solution using silk fibroin-based protein fragments is disclosed.
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公开(公告)号:US20220226223A1
公开(公告)日:2022-07-21
申请号:US17716743
申请日:2022-04-08
Applicant: Evolved By Nature, Inc.
Inventor: Gregory H. Altman , Rebecca L. Lacouture , Rachel Lee Dow , Rachel M. Lind , Dylan S. Haas
IPC: A61K8/64 , C07K1/12 , C07K14/435 , A61K9/08 , A61K38/00 , A61K38/01 , A61K8/98 , A61Q19/02 , A61K8/92 , A61K8/04 , A61K8/19 , A61K8/9789 , A61K8/9794 , A61K8/97 , A61K8/02 , A61K8/27 , A61K8/29 , A61K8/67 , A61K8/73 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A45D33/00 , A61K8/365 , A61K8/49
Abstract: A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.
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公开(公告)号:US11298310B2
公开(公告)日:2022-04-12
申请号:US16795488
申请日:2020-02-19
Applicant: Evolved By Nature, Inc.
Inventor: Gregory H. Altman , Rebecca L. Lacouture , Rachel Lee Dow , Rachel M. Lind , Dylan S. Haas
IPC: A61K9/08 , A61K8/02 , A61K38/01 , A61K8/64 , C07K1/12 , C07K14/435 , A61K38/00 , A61K8/98 , A61Q19/02 , A61K8/92 , A61K8/04 , A61K8/19 , A61K8/9789 , A61K8/9794 , A61K8/97 , A61K8/27 , A61K8/29 , A61K8/67 , A61K8/73 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A45D33/00 , A61K8/365 , A61K8/49
Abstract: A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.
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公开(公告)号:US11260012B2
公开(公告)日:2022-03-01
申请号:US15543029
申请日:2016-01-12
Applicant: Evolved By Nature, Inc.
Inventor: Gregory H. Altman , Dylan S. Haas , Rebecca L. Lacouture
IPC: A61Q19/02 , A61Q17/04 , A61K47/42 , A61K47/22 , A61K31/522 , A61K9/70 , A61K9/00 , A61K8/92 , A61K8/67 , A61K8/368 , A61Q19/08 , A61K8/04 , A61K8/64 , A61K8/365 , A61K8/49 , A61Q19/00 , A61Q17/00 , A61K8/02 , C07K14/435 , A61K8/9789
Abstract: In some embodiments, a composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals. In some embodiments, a composition is disclosed that includes silk fibroin-based protein fragments and is suitable for use in consumer applications. In some embodiments, a preserved composition is disclosed that includes silk fibroin-based protein fragments. In some embodiments, a method of preserving a solution using silk fibroin-based protein fragments is disclosed.
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公开(公告)号:US10588843B2
公开(公告)日:2020-03-17
申请号:US16453620
申请日:2019-06-26
Applicant: Evolved by Nature, Inc.
Inventor: Gregory H. Altman , Rebecca L. Horan , Rachel Lee Dow , Rachel M. Lind , Dylan S. Haas
IPC: A61K9/08 , A61K8/02 , A61K38/01 , A61K8/64 , C07K1/12 , C07K14/435 , A61K38/00 , A61K8/98 , A61Q19/02 , A61K8/92 , A61K8/04 , A61K8/19 , A61K8/27 , A61K8/29 , A61K8/67 , A61K8/73 , A61K8/97 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A45D33/00 , A61K8/365 , A61K8/49
Abstract: A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.
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公开(公告)号:US20240252413A1
公开(公告)日:2024-08-01
申请号:US18503064
申请日:2023-11-06
Applicant: Evolved by Nature, Inc.
Inventor: Gregory H. Altman , Rebecca L. Lacouture , Rachel Lee Dow , Rachel M. Lind , Dylan S. Haas
IPC: A61K8/64 , A45D33/00 , A61K8/02 , A61K8/04 , A61K8/19 , A61K8/27 , A61K8/29 , A61K8/365 , A61K8/49 , A61K8/67 , A61K8/73 , A61K8/92 , A61K8/97 , A61K8/9789 , A61K8/9794 , A61K8/98 , A61K9/08 , A61K31/375 , A61K38/00 , A61K38/01 , A61K45/06 , A61K47/02 , A61K47/12 , A61K47/36 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , C07K1/12 , C07K14/435
CPC classification number: A61K8/64 , A45D33/00 , A61K8/02 , A61K8/0216 , A61K8/042 , A61K8/19 , A61K8/27 , A61K8/29 , A61K8/365 , A61K8/4953 , A61K8/676 , A61K8/735 , A61K8/922 , A61K8/97 , A61K8/9789 , A61K8/9794 , A61K8/987 , A61K9/08 , A61K31/375 , A61K38/00 , A61K38/012 , A61K45/06 , A61K47/02 , A61K47/12 , A61K47/36 , A61Q17/04 , A61Q19/00 , A61Q19/007 , A61Q19/02 , A61Q19/08 , C07K1/12 , C07K14/43586 , A61K2800/591 , A61K2800/72 , A61K2800/74 , A61K2800/75
Abstract: A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.
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公开(公告)号:US20240189204A1
公开(公告)日:2024-06-13
申请号:US18336431
申请日:2023-06-16
Applicant: Evolved By Nature, Inc.
Inventor: Gregory H. Altman , Dylan S. Haas , Kevin T. Healy
IPC: A61K8/64 , A61K8/04 , A61K8/06 , A61K8/19 , A61K8/20 , A61K8/27 , A61K8/29 , A61K8/36 , A61K8/365 , A61K8/368 , A61K8/37 , A61K8/49 , A61K8/67 , A61K8/73 , A61K8/92 , A61K8/9789 , A61Q1/04 , A61Q1/06 , A61Q5/02 , A61Q5/12 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , A61Q19/10
CPC classification number: A61K8/64 , A61K8/042 , A61K8/062 , A61K8/064 , A61K8/19 , A61K8/20 , A61K8/27 , A61K8/29 , A61K8/361 , A61K8/365 , A61K8/368 , A61K8/37 , A61K8/4953 , A61K8/676 , A61K8/678 , A61K8/735 , A61K8/922 , A61K8/9789 , A61Q1/04 , A61Q5/02 , A61Q5/12 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61Q19/007 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61K2800/10 , A61K2800/28 , A61K2800/30 , A61K2800/805 , A61Q1/06
Abstract: In an embodiment, a moisturizing composition includes a silk solution, wherein the silk solution comprises about 1% to about 10% (w/v) of pure silk fibroin-based protein fragments that are substantially devoid of sericin; hyaluronic acid; an oil or butter; and a pH adjusting agent.
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公开(公告)号:US11878070B2
公开(公告)日:2024-01-23
申请号:US15570653
申请日:2016-04-29
Applicant: Evolved By Nature, Inc.
Inventor: Gregory H. Altman , Dylan S. Haas , Kevin T. Healy
IPC: A61K8/64 , A61K8/04 , A61K8/06 , A61K8/19 , A61K8/20 , A61K8/27 , A61K8/29 , A61K8/36 , A61K8/365 , A61K8/368 , A61K8/37 , A61K8/49 , A61K8/67 , A61Q5/02 , A61Q5/12 , A61Q15/00 , A61K8/73 , A61Q17/04 , A61K8/92 , A61Q19/00 , A61K8/9789 , A61Q1/04 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61Q1/06
CPC classification number: A61K8/64 , A61K8/042 , A61K8/062 , A61K8/064 , A61K8/19 , A61K8/20 , A61K8/27 , A61K8/29 , A61K8/361 , A61K8/365 , A61K8/368 , A61K8/37 , A61K8/4953 , A61K8/676 , A61K8/678 , A61K8/735 , A61K8/922 , A61K8/9789 , A61Q1/04 , A61Q5/02 , A61Q5/12 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61Q19/007 , A61Q19/02 , A61Q19/08 , A61Q19/10 , A61K2800/10 , A61K2800/28 , A61K2800/30 , A61K2800/805 , A61Q1/06
Abstract: In an embodiment, a moisturizing composition includes a silk solution, wherein the silk solution comprises about 1% to about 10% (w/v) of pure silk fibroin-based protein fragments that are substantially devoid of sericin; hyaluronic acid; an oil or butter; and a pH adjusting agent.
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公开(公告)号:US11857664B2
公开(公告)日:2024-01-02
申请号:US17716743
申请日:2022-04-08
Applicant: Evolved By Nature, Inc.
Inventor: Gregory H. Altman , Rebecca L. Lacouture , Rachel Lee Dow , Rachel M. Lind , Dylan S. Haas
IPC: A61K9/08 , A61K8/02 , A61K38/01 , A61K8/64 , C07K1/12 , C07K14/435 , A61K38/00 , A61K8/98 , A61Q19/02 , A61K8/92 , A61K8/04 , A61K8/19 , A61K8/9789 , A61K8/9794 , A61K8/97 , A61K31/375 , A61K45/06 , A61K47/02 , A61K47/12 , A61K47/36 , A61K8/27 , A61K8/29 , A61K8/67 , A61K8/73 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A45D33/00 , A61K8/365 , A61K8/49
CPC classification number: A61K8/64 , A45D33/00 , A61K8/02 , A61K8/0216 , A61K8/042 , A61K8/19 , A61K8/27 , A61K8/29 , A61K8/365 , A61K8/4953 , A61K8/676 , A61K8/735 , A61K8/922 , A61K8/97 , A61K8/9789 , A61K8/9794 , A61K8/987 , A61K9/08 , A61K31/375 , A61K38/00 , A61K38/012 , A61K45/06 , A61K47/02 , A61K47/12 , A61K47/36 , A61Q17/04 , A61Q19/00 , A61Q19/007 , A61Q19/02 , A61Q19/08 , C07K1/12 , C07K14/43586 , A61K2800/591 , A61K2800/72 , A61K2800/74 , A61K2800/75
Abstract: A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.
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