公开(公告)号：US20170229830A1

公开(公告)日：2017-08-10

申请号：US15266709

申请日：2016-09-15

Applicant: FUJIFILM Corporation

Inventor： Kazuhiro HIROTA ,  Hiroyasu ISHII ,  Takuji TADA

IPC: H01S3/02 ,  H01S3/093 ,  H01S3/06 ,  A61B5/00

CPC classification number: H01S3/025 ,  A61B5/0095 ,  H01S3/0407 ,  H01S3/061 ,  H01S3/093 ,  H01S3/0931

Abstract: In a solid-state laser device and a photoacoustic measurement device including the solid-state laser device, the distance between a laser rod and a flash lamp is narrowed. A shielding lid shields mirrors and an optical path of laser light from the outside. A first portion of a frame body of a laser chamber is exposed from the shielding lid. A flash lamp stored in the frame body of the laser chamber is able to be removed from and inserted into the first portion of the frame body. A thin film portion having a thickness smaller than the thickness of other portions of the shielding lid is provided in at least a part of a region of the shielding lid covering the optical path of a light beam on the outside in a longitudinal direction from the first portion of the frame body of the laser chamber.

公开(公告)号：US20130129049A1

公开(公告)日：2013-05-23

申请号：US13736613

申请日：2013-01-08

Applicant: FUJIFILM Corporation

Inventor： Hiroyasu ISHII

IPC: G01N23/04

CPC classification number: G01N23/04 ,  A61B6/4208 ,  A61B6/4291 ,  A61B6/484

Abstract: An X-ray imaging system is composed of an X-ray source, first and second absorption-type gratings, and a flat panel detector (FPD). Images are captured with the second absorption-type grating moved in X direction orthogonal to its grating line, relative to the first absorption-type grating. The FPD has pixels arranged in the X direction and Y direction orthogonal to the X direction. A group of the pixels arranged in the X direction are connected to a single signal line for reading out charge. A differential phase image producing section produces a differential phase image based on pieces of image data obtained from the respective images captured. A phase contrast image producing section integrates the differential phase image, produced by the differential phase image producing section, in a direction corresponding to the signal line of the FPD to produce a phase contrast image.

Abstract translation: X射线成像系统由X射线源，第一和第二吸收型光栅以及平板检测器（FPD）组成。 与第二吸收型光栅相对于第一吸收型光栅在与X光方向正交的第二吸收型光栅捕获图像。 FPD具有沿与X方向正交的X方向和Y方向排列的像素。 沿X方向排列的一组像素连接到用于读出电荷的单个信号线。 差分相位图像产生部分基于从所拍摄的各个图像获得的图像数据产生差分相位图像。 相位差图像产生部分将由差分相位图像产生部分产生的差分相位图像在对应于FPD的信号线的方向上进行积分，以产生相位差图像。

公开(公告)号：US20240210392A1

公开(公告)日：2024-06-27

申请号：US18424108

申请日：2024-01-26

Applicant: FUJIFILM Corporation

Inventor： Hiroyasu ISHII

IPC: G01N33/543 ,  B01L3/00 ,  G01N21/78

CPC classification number: G01N33/54389 ,  B01L3/5023 ,  G01N21/78 ,  B01L2200/16 ,  B01L2300/069 ,  B01L2300/0825 ,  B01L2400/0406

Abstract: Provided is an assay cartridge capable of improving the throughput of the assay by shortening the time until the bubbles generated in the assay region disappear as compared with the prior art. The assay cartridge includes an assay strip that has, on the surface thereof, an assay region in which a color development state changes depending on whether a sample is positive or negative, an accommodating part that accommodates an amplifying liquid that amplifies the color development of the assay region, and the assay cartridge that is supplied from the accommodating part, an absorber that absorbs at least a part of the amplifying liquid which flows on the surface of the assay strip toward the assay region and has passed through the assay region.

公开(公告)号：US20240198327A1

公开(公告)日：2024-06-20

申请号：US18416465

申请日：2024-01-18

Applicant: FUJIFILM Corporation

Inventor： Hiroyasu ISHII

IPC: B01L3/00

CPC classification number: B01L3/5023 ,  B01L2200/143 ,  B01L2300/0627 ,  B01L2300/0825

Abstract: The immunochromatographic assay apparatus includes a loading part in which a cartridge including an assay strip having an assay region is attachably and detachably loaded, a detection unit that detects the density of the assay region, a processor configured to perform a positive-negative determination of whether the sample is positive or negative based on the density acquired from the detection unit. The processor is configured to start acquisition of the density from the detection unit from a preset time point before the density of the assay region is saturated, and perform saturation point determination of whether or not the density has reached a saturation point based on a time change of the density, and in a case where it is determined in the saturation point determination that the density has reached the saturation point, perform the positive-negative determination.

公开(公告)号：US20240060974A1

公开(公告)日：2024-02-22

申请号：US18473125

申请日：2023-09-22

Applicant: FUJIFILM Corporation

Inventor： Yoshihiro SETO ,  Hiroyasu ISHII

IPC: G01N33/543 ,  B01L3/00

CPC classification number: G01N33/54387 ,  B01L3/5023 ,  B01L2200/04 ,  B01L2200/0689 ,  B01L2200/16 ,  B01L2300/069

Abstract: An assay cartridge is an assay cartridge used for immunochromatographic assay, including a carrier to which a sample and a reagent are supplied, an enclosing body in which a reagent to be supplied to the carrier is enclosed, and which has a sealing portion that opens earlier than other portions in a case where an internal pressure is increased due to an application of a pressing force, and a case accommodating the carrier and the enclosing body and having a pressing operation part for applying the pressing force to the enclosing body.

公开(公告)号：US20240019427A1

公开(公告)日：2024-01-18

申请号：US18476849

申请日：2023-09-28

Applicant: FUJIFILM Corporation

Inventor： Yoshihiro ABURAYA ,  Yasutake TANAKA ,  Daisuke OKAMURA ,  Hiroyasu ISHII

IPC: G01N33/543 ,  B01L3/00

CPC classification number: G01N33/54388 ,  B01L3/5023 ,  B01L2200/04 ,  B01L2200/16 ,  B01L2300/0654 ,  B01L2300/0825 ,  B01L2300/069

Abstract: The assay apparatus includes a loading part into which a cartridge including a carrier and a case is attachably and detachably to be loaded, the carrier having an assay region in which a color development state changes depending on whether the sample is positive or negative, and an index region which is optically distinguishable from other regions regardless of whether a sample is positive or negative, the case accommodating the carrier; a light source that illuminates the observation region on the carrier including the assay region and the index region; an imaging unit that images the observation region; and a processor configured to acquire an image including the observation region from the imaging unit, detect a position of the index region from the acquired image, and specify a position of the assay region with reference to the detected position of the index region.

公开(公告)号：US20230228748A1

公开(公告)日：2023-07-20

申请号：US18181691

申请日：2023-03-10

Applicant: FUJIFILM Corporation

Inventor： Hiroyasu ISHII ,  Junya YOSHIDA ,  Yoshihiro ABURAYA

IPC: G01N33/569 ,  G01N1/40

CPC classification number: G01N33/5695 ,  G01N1/405 ,  G01N2469/10

Abstract: There are provided a sample solution concentration method that makes it possible to obtain a sample solution concentrated solution having a desired concentration fold ratio and a sample solution examination method using the sample solution concentration method. The sample solution concentration method includes, in the following order, a sample solution injection step of injecting a sample solution, which is an aqueous solution containing a high-molecular-weight molecule, into a cylinder accommodating a particulate super absorbent polymer, a water absorption step in which water contained in the sample solution injected into the cylinder is absorbed by the super absorbent polymer accommodated in the cylinder to generate a sample solution concentrate which is a concentrate of the sample solution, in the cylinder, a liquid addition step of adding a liquid having an amount smaller than an amount of the sample solution injected into the cylinder in the sample solution injection step, to the sample solution concentrate, and a taking-out step of inserting, into the cylinder, a piston insertable into the cylinder, the piston including a tip part having holes smaller than a particle diameter of the super absorbent polymer after water absorption, to take out a sample solution concentrated solution, which is a concentrated solution of the sample solution, through the holes in the tip part of the piston.

公开(公告)号：US20150071403A1

公开(公告)日：2015-03-12

申请号：US14520954

申请日：2014-10-22

Applicant: FUJIFILM Corporation

Inventor： Hiroyasu ISHII

IPC: A61B6/00

CPC classification number: A61B6/4291 ,  A61B6/4233 ,  A61B6/4452 ,  A61B6/4464 ,  A61B6/484 ,  A61B6/502 ,  A61B6/5282 ,  G01N23/04

Abstract: In a radiographic system and a radiographic image generating method that generate a phase contrast image and an absorption image of an subject, the absorption image in which density irregularity is removed or reduced is generated on the basis of a plurality of pieces of image data obtained for generating the phase contrast image.

Abstract translation: 在产生相位对比图像和被摄体的吸收图像的射线照相系统和放射线照相图像生成方法中，基于为了获得的多个图像数据而生成其中去除或减少浓度不规则的吸收图像 产生相位差图像。

公开(公告)号：US20130083893A1

公开(公告)日：2013-04-04

申请号：US13629293

申请日：2012-09-27

Applicant: Fujifilm Corporation

Inventor： Hiroyasu ISHII

IPC: G06K9/34 ,  G01N23/04

CPC classification number: A61B6/484 ,  A61B6/4291 ,  G01N23/20075 ,  G01N2223/304 ,  G01N2223/401 ,  G21K2207/005

Abstract: A radiation imaging apparatus includes a differential phase image producing section, a phase unwrapping section, a statistical operation section, and a correction processing section. The differential phase image producing section produces a differential phase image in which pixel values are wrapped into a predetermined range α. The phase unwrapping section performs a phase unwrapping process to the differential phase image. The statistical operation section obtains a mode from statistical operation of pixel values in each subregion segmented in the unwrapped differential phase image. Each subregion is a unit in which error caused by the phase unwrapping process is to be corrected. The correction processing section calculates, for each pixel, an integer “n” which allows a difference Δ between the mode and a pixel value of each pixel to satisfy nα−α/2≦Δ

Abstract translation: 辐射摄像装置包括差分相位图像产生部分，相位展开部分，统计运算部分和校正处理部分。 差分相位图像产生部分产生像素值被包裹在预定范围α内的差分相位图像。 相位展开部对差分相位图像执行相位展开处理。 统计运算部分从展开的差分相位图像中分割的每个子区域中的像素值的统计运算获得模式。 每个子区域是其中由相位展开处理引起的误差被校正的单元。 校正处理部针对每个像素计算允许差值Dgr的整数n; 在每个像素的模式和像素值之间满足nα-α/ 2＆nlE;＆Dgr;