Devices, systems, and methods of packaging for a pre-filled drug delivery device

    公开(公告)号:US11517658B2

    公开(公告)日:2022-12-06

    申请号:US16897988

    申请日:2020-06-10

    Inventor: Ian McLaughlin

    Abstract: A system for sterilizing a drug delivery device includes a drug delivery device having a first self-healing seal configured to seal a fluid reservoir disposed within the drug delivery device. A sealable container is configured to receive the drug delivery device therein. The sealable container has a base portion and a cover portion. The cover portion has a second self-healing seal positioned to align with the first self-healing seal when the drug delivery device is disposed within the sealable container. A fill port includes a fill path, the fill path being configured to pass through the first and second self-healing seals to fluidly couple the fill port to the reservoir of the drug delivery device. Other systems, methods, and devices of sterilization are also disclosed.

    Drug delivery device with indicator

    公开(公告)号:US11497856B2

    公开(公告)日:2022-11-15

    申请号:US16534376

    申请日:2019-08-07

    Abstract: Systems and methods for monitoring an operational state and/or a fill status of a drug container of a drug delivery device are provided. The drug container can hold a liquid drug. A plunger can be positioned within the drug container. A drive system can advance the plunger to expel the liquid drug from the container. A monitoring system can detect a movement and/or a position of the plunger and/or any component coupled to the plunger. The detection can enable determination of an amount of liquid drug that has been expelled and/or an amount of liquid drug remaining in the drug container. Dosing rates, flow rates, and dosage completion can also be determined.

    Methods for forming low stress component for medical devices

    公开(公告)号:US11305333B2

    公开(公告)日:2022-04-19

    申请号:US16836356

    申请日:2020-03-31

    Inventor: Ian McLaughlin

    Abstract: Disclosed herein are approaches of forming a component, such as a valve, for a medical device. One approach includes providing a cylinder within a tube, the tube and the cylinder joined together in an interference fit, and annealing the tube and the cylinder, wherein the tube and the cylinder are no longer joined together in the interference fit following the annealing.

    Needle insertion mechanisms for drug containers

    公开(公告)号:US11045603B2

    公开(公告)日:2021-06-29

    申请号:US15901082

    申请日:2018-02-21

    Abstract: Systems for piercing a septum of a drug delivery device is disclosed. The drug delivery device may include a needle conduit having an end and a drug container having a septum. The septum piercing mechanism may include a needle support operatively coupled to the needle conduit. The septum piercing mechanism may be movable from a first, unactivated configuration to a second, activated configuration. In the unactivated configuration, the septum seals an interior of the drug container from the end of the needle conduit. In the activated configuration, the end of the needle conduit pierces through the septum placing the needle conduit in fluid communication with the drug container. In one embodiment, activation may cause the needle support to move towards the drug container. In one embodiment, the needle support may be moved by a biasing member. Alternatively, in another embodiment, the needle support may be moved by a cam mechanism.

    Fluid flow regulation arrangements for drug delivery devices

    公开(公告)号:US10973978B2

    公开(公告)日:2021-04-13

    申请号:US16049388

    申请日:2018-07-30

    Abstract: A fluid flow regulator of a fluid delivery system that can adjust a flow rate of a liquid drug dispensed from a liquid drug container to a user is provided. The fluid flow regulator can be coupled to an end of the liquid drug container. The fluid flow regulator can include a compliance plate and a flow channel selector plate having a fluid flow channel. The flow channel selector plate can be rotated relative to the compliance plate and the liquid drug container to expose a selected portion of the fluid flow channel to openings in the compliance plate that are in fluid communication with the liquid drug stored in the liquid drug container. The selected portion of the fluid flow channel can correspond to a corresponding flow resistance of the liquid drug through the fluid flow channel, thereby regulating the flow of the liquid drug to the user.

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