Process for producing methacrolein and methacrylic acid
    21.
    发明授权
    Process for producing methacrolein and methacrylic acid 失效
    甲基丙烯醛和甲基丙烯酸的制备方法

    公开(公告)号:US4320227A

    公开(公告)日:1982-03-16

    申请号:US109554

    申请日:1980-01-04

    摘要: A process for producing methacrolein and methacrylic acid by oxidizing isobutyl aldehyde with molecular oxygen or molecular oxygen-containing gas in the vapor phase characterized by the use of a catalyst of heteropoly-acid or a mixture of heterpoly-acid and its salt which has the general formula:Mo.sub.a V.sub.b P.sub.c X.sub.d Y.sub.e O.sub.fwherein Mo, V, P and O represent respectively molybdenum, vanadium, phosphorus and oxygen, X represents one or more elements selected from the group consisting of copper, tin, thorium, aluminum, germanium, nickel, iron, cobalt, zinc, titanium, lead, rhenium, zirconium, cerium, chromium, bismuth and arsenic, Y represents one or more elements selected from the group consisting of potassium, rubidium, cesium and thallium and a, b, c, d, e and f represent the atomic ratio of the elements where,a is 10,b is a number of 6 or less than 6 excluding 0,c is a number of 0.5 to 6,d is a number of 3 or less than 3 excluding 0,e is a number of 0 to 0.8,f is a number determined depending on the valency and atomic ratio of other elements.

    摘要翻译: 在气相中用分子氧或分子含氧气体氧化异丁醛生产甲基丙烯醛和甲基丙烯酸的方法,其特征在于使用杂多酸催化剂或异戊酸及其盐的混合物,其具有一般性 式:MoaVbPcXdYeOf其中Mo,V,P和O分别代表钼,钒,磷和氧,X代表一种或多种选自铜,锡,钍,铝,锗,镍,铁,钴,锌 ,钛,铅,铼,锆,铈,铬,铋和砷,Y表示选自钾,铷,铯和铊的一种或多种元素,a,b,c,d,e和f表示 元素的原子比,a为10,b为6以下的数,6为不含0,c为0.5〜6的数,d为不包括0的数3或小于3,e为数 为0〜0.8,f为取决于决定的数 关于其他元素的化合价和原子比。

    POLYNUCLEOTIDE CONSTRUCT CAPABLE OF DISPLAYING FAB IN A CELL-FREE TRANSLATION SYSTEM, AND METHOD FOR MANUFACTURING AND SCREENING FAB USING SAME
    23.
    发明申请
    POLYNUCLEOTIDE CONSTRUCT CAPABLE OF DISPLAYING FAB IN A CELL-FREE TRANSLATION SYSTEM, AND METHOD FOR MANUFACTURING AND SCREENING FAB USING SAME 有权
    可在无细胞翻译系统中显示FAB的多核苷酸结构,以及使用其制造和筛选FAB的方法

    公开(公告)号:US20130288908A1

    公开(公告)日:2013-10-31

    申请号:US13990654

    申请日:2011-11-30

    IPC分类号: G01N33/68

    摘要: The polynucleotide construct of (1) or (2) below is used to perform ribosome display, CIS display and/or mRNA display in order to screen a Fab against an antigen of interest: (1) a polynucleotide construct which monocistronically comprises a ribosome-binding sequence, Fab first chain-coding sequence, linker peptide-coding sequence, Fab second chain-coding sequence and scaffold-coding sequence in this order, and further comprises at its 3′-end a structure necessary for maintaining a complex with the Fab encoded by itself, and (2) a polynucleotide construct which comprises a Fab first chain-expressing cistron and a Fab second chain-expressing cistron each containing a ribosome-binding sequence, a Fab first chain-coding sequence or Fab second chain-coding sequence, and a scaffold-coding sequence in this order, the first Fab-expressing cistron further comprising at its 3′-end a ribosome stall sequence, said Fab second chain-expressing cistron further comprising at its 3′-end a structure necessary for maintaining a complex with the Fab encoded by itself.

    摘要翻译: 以下的(1)或(2)的多核苷酸构建体用于进行核糖体展示,CIS显示和/或mRNA显示,以便针对感兴趣的抗原筛选Fab:(1)单核细胞系包含核糖体 - 结合序列,Fab第一链编码序列,接头肽编码序列,Fab第二链编码序列和支架编码序列,并且在其3'末端还包含与Fab保持复合物所必需的结构 其自身编码,和(2)包含Fab第一链表达顺反子和Fab第二链表达顺反子的多核苷酸构建体,其各自含有核糖体结合序列,Fab第一链编码序列或Fab第二链编码序列 和支架编码序列,所述第一Fab表达顺反子在其3'末端进一步包含核糖体失速序列,所述Fab第二链表达顺反子在其3'末端还包含结构ne 维持与Fab自身编码的复合物的塞车。

    PROCESS FOR PRODUCING SUCCINIC ACID
    24.
    发明申请
    PROCESS FOR PRODUCING SUCCINIC ACID 有权
    生产肝酸的方法

    公开(公告)号:US20090234160A1

    公开(公告)日:2009-09-17

    申请号:US12374203

    申请日:2007-06-12

    IPC分类号: C07C51/47 C07C51/42

    CPC分类号: C07C51/43 C07C51/02 C07C55/10

    摘要: The present invention is intended to provide a process capable of efficiently producing highly purified succinic acid from an alkali metal succinate by a simple separation and purification process.The process for producing succinic acid in the present invention comprises (1) the step to add sulfuric acid into a solution containing an alkali metal succinate, (2) the step to precipitate and remove the crystal of an alkali metal sulfate from said solution, and (3) the step to precipitate and recover the crystal of succinic acid. The removal of the crystal of an alkali metal sulfate in the step (2) is performed by a solid-liquid separation in a state that the crystal of alkali metal sulfate is precipitated by concentrating and heating the solution that is obtained by adding sulfuric acid in the step (1) and succinic acid is dissolved in the solution.

    摘要翻译: 本发明旨在提供一种能够通过简单的分离和纯化方法从琥珀酸碱金属有效地制备高纯度琥珀酸的方法。 本发明的琥珀酸的制造方法包括(1)将硫酸添加到含有碱金属琥珀酸盐的溶液中的步骤,(2)从所述溶液中析出并除去碱金属硫酸盐的结晶的工序, (3)沉淀并回收琥珀酸晶体的步骤。 在步骤(2)中去除碱金属硫酸盐的晶体是通过在通过浓缩和加热通过加入硫酸获得的溶液来沉淀碱金属硫酸盐的结晶的固液分离 将步骤(1)和琥珀酸溶解在溶液中。

    Cosmetic composition
    25.
    发明授权
    Cosmetic composition 有权
    化妆品组成

    公开(公告)号:US06500415B2

    公开(公告)日:2002-12-31

    申请号:US09873398

    申请日:2001-06-05

    IPC分类号: A61K3174

    摘要: A cosmetic composition comprising titanium oxide coated with one or both of silica and alumina or zinc oxide coated with one or both of silica and alumina, and a thickening polymer having a carboxyl group in the side chain, preferably a carboxyvinyl polymer, wherein when 10% by mass of silica- and/or alumina-coated titanium oxide or silica- and/or alumina-coated zinc oxide is dispersed in an aqueous solution containing 0.133% by mass of a carboxyvinyl polymer, the viscosity after the passing of 100 hours is 50% or more of the initial viscosity. A cosmetic composition comprising titanium oxide coated with one or both silica and alumina or zinc oxide coated with one or both of silica and alumina, and a thickening polymer having a carboxyl group in the side chain of the invention, can maintain emulsion stability by thickening of polymer for a long period of time and can be widely and suitably used for ultraviolet shielding cosmetic materials or the like having preparation form stability.

    摘要翻译: 一种化妆品组合物,其包含用二氧化硅和氧化铝中的一种或二者涂覆的二氧化钛或涂覆有二氧化硅和氧化铝中的一种或两种的氧化锌,以及在侧链中具有羧基的增稠聚合物,优选羧基乙烯基聚合物,其中当10% 的二氧化硅和/或氧化铝涂覆的氧化钛或二氧化硅和/或氧化铝涂覆的氧化锌分散在含有0.133质量%羧基乙烯基聚合物的水溶液中,100小时后的粘度为50 %以上的初始粘度。 包含二氧化硅和氧化铝或二氧化硅或二氧化硅和氧化铝中的一种或二者涂覆的二氧化钛的化妆品组合物和本发明侧链具有羧基的增稠聚合物可以通过增稠而保持乳液的稳定性 聚合物长时间并且可广泛适用于具有制备形式稳定性的紫外线屏蔽化妆品等。