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公开(公告)号：US20130243936A1
公开(公告)日：2013-09-19
申请号：US13781385
申请日：2013-02-28
Applicant: MICROVENTION, INC.
Inventor： Joshua Garretson , John Belletto , Gregory M. Cruise
IPC: B05D5/00 , C09D171/08
CPC classification number: B05D5/00 , A61L29/085 , A61L31/10 , A61L2420/02 , B05D3/142 , B05D2503/00 , C08G18/4833 , C08G18/7831 , C09D171/08 , C09D175/08
Abstract: Described herein are methods of coating both metallic and polymeric surfaces adding hydrophilicity comprising the steps mixing a coating composition comprising at least one polyol, at least one compound having at least two isocyanate groups, and an organic solvent; introducing nucleophilic functional groups on the surface thereby creating an active surface; subjecting the active surface to the coating composition thereby forming a coated surface; and curing the coated surface. Medical devices, for example, implantable medical devices can be coated by the methods described herein.
Abstract translation: 本文描述了涂覆亲水性的金属和聚合物表面的方法，包括将包含至少一种多元醇，至少一种具有至少两个异氰酸酯基团的化合物和有机溶剂的涂料组合物混合的步骤; 在表面上引入亲核官能团从而产生活性表面; 使活性表面经受涂层组合物从而形成涂覆表面; 并固化涂层表面。 可以通过本文所述的方法来涂覆医疗装置，例如可植入医疗装置。
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公开(公告)号：US11857694B2
公开(公告)日：2024-01-02
申请号：US17678891
申请日：2022-02-23
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Steve Plotkin , Xinping Wu
IPC: A61L24/06 , A61L24/00 , C08F222/38
CPC classification number: A61L24/06 , A61L24/001 , C08F222/385 , A61L2430/36 , A61L24/06 , C08L33/08 , A61L24/06 , C08L33/10 , A61L24/06 , C08L33/26
Abstract: Embolic particles are described. The particles are reaction products of a prepolymer solution including at least one polyether macromer and an appropriate monomer.
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公开(公告)号：US11744925B2
公开(公告)日：2023-09-05
申请号：US16773685
申请日：2020-01-27
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Steve Plotkin , Emily Hsu
IPC: C09D133/14 , A61L29/04 , A61L29/08 , C09D135/02 , B05D3/06 , B05D7/00
CPC classification number: A61L29/085 , A61L29/041 , B05D3/067 , B05D7/546 , C09D133/14 , C09D135/02 , A61L2300/452 , A61L2400/10 , A61L2420/02 , A61L2420/08
Abstract: Lubricious coatings for medical devices and their uses are described.
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公开(公告)号：US11285240B2
公开(公告)日：2022-03-29
申请号：US17010708
申请日：2020-09-02
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Steve Plotkin , Xinping Wu
IPC: A61L24/06 , A61L24/00 , C08F222/38
Abstract: Embolic particles are described. The particles are reaction products of a prepolymer solution including at least one polyether macromer and an appropriate monomer.
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公开(公告)号：US20200368171A1
公开(公告)日：2020-11-26
申请号：US16882239
申请日：2020-05-22
Applicant: MicroVention, Inc.
Inventor： Makoto Harumoto , Gregory M. Cruise , Michael Kebede
IPC: A61K9/50 , A61K31/282 , A61K31/337 , A61K33/243 , A61K9/00
Abstract: Described are particles configured for intravascular delivery of pharmaceutical agents to a diseased site.
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Patent Agency Ranking
公开(公告)号：US10792390B2
公开(公告)日：2020-10-06
申请号：US16717965
申请日：2019-12-17
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Steve Plotkin , Xinping Wu
IPC: A61L24/06 , A61L24/00 , C08F222/38
Abstract: Embolic particles are described. The particles are reaction products of a prepolymer solution including at least one polyether macromer and an appropriate monomer.
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公开(公告)号：US20200246501A1
公开(公告)日：2020-08-06
申请号：US16750635
申请日：2020-01-23
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Xinping Wu , Matthew J. Fitz , Yue Wu
IPC: A61L24/00
Abstract: Liquid embolic preparations and medical treatment methods of using those preparations are described. In some embodiments, the preparations or solutions can transition from a liquid to a solid for use in the embolization. The preparations can include biocompatible polymers with covalently bound radioactive iodine isotopes.
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公开(公告)号：US20200069311A1
公开(公告)日：2020-03-05
申请号：US16678978
申请日：2019-11-08
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael Constant , Terrance Tran , Joseph Gulachenski
Abstract: Devices for the occlusion of body cavities, such as the embolization of vascular aneurysms and the like, and methods for making and using such devices are described.
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公开(公告)号：US20190151452A1
公开(公告)日：2019-05-23
申请号：US16250878
申请日：2019-01-17
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Clayton G. Harris , Michael J. Constant
IPC: A61K47/32 , A61K47/58 , A61L31/18 , A61L31/16 , A61L31/14 , A61K31/7068 , A61K9/00 , A61K49/04 , C07F15/00 , C07H19/06 , A61K31/787
Abstract: Polymers are described herein comprising: a reaction product of a prepolymer solution including at least one macromer and at least one visualization agent; and an active agent electrostatically bound to the polymer filament or chemically bound to the at least one monomer; wherein the polymer filament does not include metallic support members.
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公开(公告)号：US20190150932A1
公开(公告)日：2019-05-23
申请号：US16250880
申请日：2019-01-17
Applicant: MicroVention, Inc.
Inventor： Gregory M. Cruise , Michael J. Constant , Terrance Tran
Abstract: Devices for the occlusion of body cavities, such as the embolization of vascular aneurysms and the like, and methods for making and using such devices. The devices may be comprised of novel expansile materials, novel infrastructure design, or both. The devices provided are very flexible and enable deployment with reduced or no damage to bodily tissues, conduits, cavities, etceteras.
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