摘要:
Through screening of a Zymomonas mutant library the himA gene was found to be involved in the inhibitory effect of acetate on Zymomonas performance. Xylose-utilizing Zymomonas further engineered to reduce activity of the himA gene were found to have increased ethanol production in comparison to a parental strain, when cultured in medium comprising xylose and acetate.
摘要:
The present invention relates to novel benzenesulfonanilide compounds of the formulae I and I′ and physiologically tolerated acid addition salts and the N-oxides thereof. The compounds possess valuable therapeutic properties and are particularly suitable, for treating diseases that respond to modulation of the serotonin 5-HT6 receptor. wherein R1 is hydrogen or methyl R2 is hydrogen or methyl R3 hydrogen, fluorine C1-C2 alkoxy or fluorinated C1-C2 alkoxy; R4 is hydrogen, C1-C4 alkyl or fluorinated C1-C4 alkyl; R5 is hydrogen, fluorine, C1-C2 alkyl, fluorinated C1-C2 alkyl, C1-C2 alkoxy or fluorinated C1-C2 alkoxy; and R6 is hydrogen, fluorine or chlorine.
摘要:
A strain of xylose-utilizing Zymomonas was engineered with a genetic modification to the glucose-fructose oxidoreductase gene resulting in reduced expression of GFOR enzyme activity. The engineered strain exhibits reduced production of xylitol, a detrimental by-product of xylose metabolism. It also consumes more xylose and produces more ethanol during mixed sugar fermentation under process-relevant conditions.
摘要:
Xylose-utilizing Z. mobilis strains were found to have improved ethanol production when grown in medium containing mixed sugars including xylose if sorbitol or mannitol was included in the medium. The effect was seen in concentrations of mixed sugars where no growth lag period occurs, as well as in higher sugars concentrations.
摘要:
Methods of utilizing carbon nanotubes or composites thereof as hole plugs in vias or in contact holes for connecting conductive layers in integrated circuits are disclosed. Integrated circuits and integrated circuit layers formed by the methods are also disclosed.
摘要:
The invention relates to microorganisms which normally do not ferment a pentose sugar and which are genetically altered to ferment this pentose to produce ethanol. A representative example is Zymomonas mobilis which has been transformed with E. coli xylose isomerase, xylulokinase, transaldolase and transketolase genes. Expression of the added genes are under the control of Zymomonas mobilis promoters. This newly created microorganism is useful for fermenting pentoses and glucose, produced by hydrolysis of hemicellulose and cellulose, to produce ethanol.
摘要:
A method is provided for heat transfer from a surface to a fluid. The method includes directing a first fluid flow towards the surface in a first direction and directing a second fluid flow towards the surface in a second direction. The first and second fluid flows cooperate to cool the surface.
摘要:
A concrete structure member strengthened with prestressed FRP elements includes a concrete structure body and a prestressed FRP element arranged on the former. An epoxy resin overlay surrounding the prestressed FRP element is provided to wrap it up, and a polymer concrete supplemental layer is provided outside the epoxy resin overlay. The concrete structure member can uniformly and effectively transfer the stress from the prestressed FRP element.
摘要:
Critical resources are identified within a computer system such as operating system files, drivers, modules and registry keys that are used to bootstrap the computer. During a successful bootstrap, these resources are saved into persistent storage during the bootstrap phase. Changes to critical resources are monitored and these resources are backed up if they are changed. Upon computer system failure, steps of identifying the type of failure and an analysis of its root cause are optionally performed. A user is presented with a bootstrap menu and critical resources necessary to bootstrap the computer are retrieved from persistent storage and saved into their appropriate locations. A successful bootstrap is then performed of the computer system in order to recover from the failure.
摘要:
The present invention relates to benzenesulfonyl or sulfonamide compounds of formulae IA and IB wherein the variables have the meanings given in the claims and the description, pharmaceutical compositions containing them, and their use in therapy. The compounds possess valuable therapeutic properties and are particularly suitable for treating diseases that respond to modulation of the serotonin 5-HT6 receptor.