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21.发明申请Pro108 antibody compositions and methods of use and use of Pro108 to assess cancer risk 有权Pro108抗体组合物和使用和使用Pro108来评估癌症风险的方法公开(公告)号：US20050124012A1
公开(公告)日：2005-06-09
申请号：US10919215
申请日：2004-08-16
申请人： Iris Simon , Laura Corral , Charis Lawrenson , Nam Kim , Glenn Pilkington , Robert Wolfert
发明人： Iris Simon , Laura Corral , Charis Lawrenson , Nam Kim , Glenn Pilkington , Robert Wolfert
IPC分类号： C07K16/30 , G01N33/574 , A61K39/395 , C07K16/46
CPC分类号： G01N33/57415 , C07K16/30 , C07K16/3069 , G01N33/57419 , G01N33/57434 , G01N33/57446 , G01N33/57449
摘要： This invention relates to a method for assessing risk of prostate cancer. Specifically, it relates to utilizing both Pro108 and Prostate Specific Antigen (PSA) in combination to determine the risk of prostate cancer. In addition, it is directed to a method for assessing risk of ovarian, colon, breast or stomach cancer utilizing Pro108 or specific antibodies to Pro108. The invention provides isolated anti-prostate, ovarian, colon, breast or stomach cancer antigen (Pro108) antibodies that bind to Pro108 on a mammalian cell in vivo. The invention also encompasses compositions comprising an anti-Pro108 antibody and a carrier. These compositions can be provided in an article of manufacture or a kit. Another aspect of the invention is an isolated nucleic acid encoding an anti-Pro108 antibody, as well as an expression vector comprising the isolated nucleic acid. Also provided are cells that produce the anti-Pro108 antibodies. The invention encompasses a method of producing the anti-Pro108 antibodies. Other aspects of the invention are a method of killing an Pro108-expressing cancer cell, comprising contacting Pro108 present in the ECM with an anti-Pro108 antibody and a method of alleviating or treating an Pro108-expressing cancer in a mammal, comprising administering a therapeutically effective amount of the anti-Pro108 antibody to the mammal.
摘要翻译： 本发明涉及一种评估前列腺癌风险的方法。 具体来说，它涉及组合使用Pro108和前列腺特异性抗原（PSA）来确定前列腺癌的风险。 此外，它涉及使用Pro108或Pro108的特异性抗体评估卵巢癌，结肠癌，乳腺癌或胃癌的风险的方法。 本发明提供在体内在哺乳动物细胞上结合Pro108的分离的抗前列腺，卵巢，结肠，乳腺或胃癌抗原（Pro108）抗体。 本发明还包括包含抗Pro108抗体和载体的组合物。 这些组合物可以在制品或试剂盒中提供。 本发明的另一方面是编码抗Pro108抗体的分离的核酸，以及包含分离的核酸的表达载体。 还提供产生抗Pro108抗体的细胞。 本发明包括产生抗Pro108抗体的方法。 本发明的其它方面是杀死表达Pro108的癌细胞的方法，包括使ECM中存在的Pro108与抗Pro108抗体接触，以及减轻或治疗哺乳动物中Pro108表达的癌症的方法，包括给予治疗 有效量的抗Pro108抗体。
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22.发明授权公开(公告)号：US10157342B1
公开(公告)日：2018-12-18
申请号：US16044875
申请日：2018-07-25
申请人： Nam Kim
发明人： Nam Kim
摘要： A computer system for transforming sensory input received at a machine into actions by the machine. The system receives sensory input from one or more sensors. Upon determining that the sensory input corresponds to a consciousness module, the system translates the input into a human language stimulus. The system selects an action corresponding to the human language stimulus and performs the action.
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23.发明申请SYSTEM AND METHOD FOR EXTERNAL DATA ENTRY AND DISPLAY FOR PORTABLE COMMUNICATION DEVICES 审中-公开用于便携式通信设备的外部数据输入和显示的系统和方法公开(公告)号：US20130337866A1
公开(公告)日：2013-12-19
申请号：US13527495
申请日：2012-06-19
申请人： Nam Kim
发明人： Nam Kim
IPC分类号： H04W4/20
摘要： A data display and entry apparatus for a portable communication device is disclosed. The apparatus includes a data entry portion configured to receive a user data entry for use by an application executed outside the apparatus, a display portion configured to display graphics based on data associated with the application, and a data communication interface configured to receive the data associated with the application from a portable communication device and to send user-entered data indicative of the user data entry to the portable communication device using one or more data links.
摘要翻译： 公开了一种用于便携式通信设备的数据显示和输入装置。 所述装置包括：数据输入部分，被配置为接收用户数据条目供所述设备外部执行的应用使用;显示部分，被配置为基于与所述应用相关联的数据显示图形;以及数据通信接口，被配置为接收与所述数据相关联的数据 利用来自便携式通信设备的应用，并且使用一个或多个数据链路向用户数据输入发送表示用户数据输入的用户输入的数据到便携式通信设备。
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24.发明授权Pro108 antibody compositions and methods of use and use of Pro108 to assess cancer risk 有权Pro108抗体组合物和使用和使用Pro108来评估癌症风险的方法公开(公告)号：US08148093B2
公开(公告)日：2012-04-03
申请号：US11866475
申请日：2007-10-03
申请人： Iris Simon , Laura Corral , Charis Lawrenson , Nam Kim , Glenn Pilkington , Robert L. Wolfert
发明人： Iris Simon , Laura Corral , Charis Lawrenson , Nam Kim , Glenn Pilkington , Robert L. Wolfert
IPC分类号： G01N33/53 , G01N33/574 , G01N33/60
CPC分类号： G01N33/57415 , C07K16/30 , C07K16/3069 , G01N33/57419 , G01N33/57434 , G01N33/57446 , G01N33/57449
摘要： This invention relates to a method for assessing risk of prostate cancer. Specifically, it relates to utilizing both Pro108 and Prostate Specific Antigen (PSA) in combination to determine the risk of prostate cancer. In addition, it is directed to a method for assessing risk of ovarian, colon, breast or stomach cancer utilizing Pro108 or specific antibodies to Pro108. The invention provides isolated anti-prostate, ovarian, colon, breast or stomach cancer antigen (Pro108) antibodies that bind to Pro108 on a mammalian cell in vivo. The invention also encompasses compositions comprising an anti-Pro108 antibody and a carrier. These compositions can be provided in an article of manufacture or a kit. Another aspect of the invention is an isolated nucleic acid encoding an anti-Pro108 antibody, as well as an expression vector comprising the isolated nucleic acid. Also provided are cells that produce the anti-Pro108 antibodies. The invention encompasses a method of producing the anti-Pro108 antibodies. Other aspects of the invention are a method of killing an Pro108-expressing cancer cell, comprising contacting Pro108 present in the ECM with an anti-Pro108 antibody and a method of alleviating or treating an Pro108-expressing cancer in a mammal, comprising administering a therapeutically effective amount of the anti-Pro108 antibody to the mammal.
摘要翻译： 本发明涉及一种评估前列腺癌风险的方法。 具体来说，它涉及组合使用Pro108和前列腺特异性抗原（PSA）来确定前列腺癌的风险。 此外，它涉及使用Pro108或Pro108的特异性抗体评估卵巢癌，结肠癌，乳腺癌或胃癌的风险的方法。 本发明提供在体内在哺乳动物细胞上结合Pro108的分离的抗前列腺，卵巢，结肠，乳腺或胃癌抗原（Pro108）抗体。 本发明还包括包含抗Pro108抗体和载体的组合物。 这些组合物可以在制品或试剂盒中提供。 本发明的另一方面是编码抗Pro108抗体的分离的核酸，以及包含分离的核酸的表达载体。 还提供产生抗Pro108抗体的细胞。 本发明包括产生抗Pro108抗体的方法。 本发明的其它方面是杀死表达Pro108的癌细胞的方法，包括使ECM中存在的Pro108与抗Pro108抗体接触，以及减轻或治疗哺乳动物中Pro108表达的癌症的方法，包括给予治疗 有效量的抗Pro108抗体。
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25.发明授权Pro108 antibody compositions and methods of use and use of Pro108 to assess cancer risk 有权Pro108抗体组合物和使用和使用Pro108来评估癌症风险的方法公开(公告)号：US07294704B2
公开(公告)日：2007-11-13
申请号：US10919215
申请日：2004-08-16
申请人： Iris Simon , Laura Corral , Charis Lawrenson , Nam Kim , Glenn Pilkington , Robert L. Wolfert
发明人： Iris Simon , Laura Corral , Charis Lawrenson , Nam Kim , Glenn Pilkington , Robert L. Wolfert
IPC分类号： C07K16/00
CPC分类号： G01N33/57415 , C07K16/30 , C07K16/3069 , G01N33/57419 , G01N33/57434 , G01N33/57446 , G01N33/57449
摘要： This invention relates to a method for assessing risk of prostate cancer. Specifically, it relates to utilizing both Pro108 and Prostate Specific Antigen (PSA) in combination to determine the risk of prostate cancer. In addition, it is directed to a method for assessing risk of ovarian, colon, breast or stomach cancer utilizing Pro108 or specific antibodies to Pro108. The invention provides isolated anti-prostate, ovarian, colon, breast or stomach cancer antigen (Pro108) antibodies that bind to Pro108 on a mammalian cell in vivo. The invention also encompasses compositions comprising an anti-Pro108 antibody and a carrier. These compositions can be provided in an article of manufacture or a kit. Another aspect of the invention is an isolated nucleic acid encoding an anti-Pro108 antibody, as well as an expression vector comprising the isolated nucleic acid. Also provided are cells that produce the anti-Pro108 antibodies. The invention encompasses a method of producing the anti-Pro108 antibodies. Other aspects of the invention are a method of killing an Pro108-expressing cancer cell, comprising contacting Pro108 present in the ECM with an anti-Pro108 antibody and a method of alleviating or treating an Pro108-expressing cancer in a mammal, comprising administering a therapeutically effective amount of the anti-Pro108 antibody to the mammal.
摘要翻译： 本发明涉及一种评估前列腺癌风险的方法。 具体来说，它涉及组合使用Pro108和前列腺特异性抗原（PSA）来确定前列腺癌的风险。 此外，它涉及使用Pro108或Pro108的特异性抗体评估卵巢癌，结肠癌，乳腺癌或胃癌的风险的方法。 本发明提供在体内在哺乳动物细胞上结合Pro108的分离的抗前列腺，卵巢，结肠，乳腺或胃癌抗原（Pro108）抗体。 本发明还包括包含抗Pro108抗体和载体的组合物。 这些组合物可以在制品或试剂盒中提供。 本发明的另一方面是编码抗Pro108抗体的分离的核酸，以及包含分离的核酸的表达载体。 还提供产生抗Pro108抗体的细胞。 本发明包括产生抗Pro108抗体的方法。 本发明的其它方面是杀死表达Pro108的癌细胞的方法，包括使ECM中存在的Pro108与抗Pro108抗体接触，以及减轻或治疗哺乳动物中Pro108表达的癌症的方法，包括给予治疗 有效量的抗Pro108抗体。
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26.发明申请Stable Pharmaceutical Composition Containing Benzimidazole Derivatives and Method of Manufacturing the Same 审中-公开包含苯并咪唑衍生物的稳定药物组合物及其制备方法公开(公告)号：US20070212408A1
公开(公告)日：2007-09-13
申请号：US11587720
申请日：2005-04-27
申请人： Nam Kim , Jin Choi , Jae Kim , Nam Lee , Je Ryu , Yong Hwang , Yong Oh , Dong Min , Key Um , Wei-Jong Kwak , Do Kum
发明人： Nam Kim , Jin Choi , Jae Kim , Nam Lee , Je Ryu , Yong Hwang , Yong Oh , Dong Min , Key Um , Wei-Jong Kwak , Do Kum
IPC分类号： A61K31/724 , C08B30/18 , A61K9/48 , A61K9/20
CPC分类号： B82Y5/00 , A61K47/6951
摘要： The present invention relates to an inclusion complex containing a benzimidazole derivative with excellent storage stability and a method of its preparation. In particular, the present invention relates to an inclusion complex containing a benzimidazole derivative with improved storage stability and a method of its preparation, where an inclusion complex is manufactured by performing an inclusion reaction by combining a benzimidazole derivative, cyclodextrin and a water-soluble polymer in an aqueous alkali solution in order to be formulated after stabilizing an acid-unstable benzimidazole derivative.
摘要翻译： 本发明涉及包含具有优异储存稳定性的苯并咪唑衍生物的包合络合物及其制备方法。 特别地，本发明涉及包含具有改进的储存稳定性的苯并咪唑衍生物的包合络合物及其制备方法，其中通过将苯并咪唑衍生物，环糊精和水溶性聚合物组合进行包合反应来制备包合络合物 在碱性水溶液中，为了在稳定酸不稳定的苯并咪唑衍生物后配制。
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公开(公告)号：US20070096205A1
公开(公告)日：2007-05-03
申请号：US11590373
申请日：2006-10-30
IPC分类号： H01L29/76 , H01L21/336
CPC分类号： H01L27/0629 , H01L29/1083 , H01L29/404 , H01L29/42368 , H01L29/7831 , H01L29/7835
摘要： Disclosed are a power semiconductor device and a method for manufacturing the same. The power semiconductor device has a PIP capacitor and an LDMOS transistor, the LDMOS transistor having second and third gate electrodes separate from a first gate electrode, which may be formed in the process of forming the upper electrode of the PIP capacitor, so it is possible to realize an LDMOS having a higher breakdown voltage and lower Ron and Rsp without additional processing. A drain voltage, which may be different from a voltage applied to the first gate electrode, may be applied to the third gate electrode, so it is possible to realize an LDMOS having a high breakdown voltage and low Ron and Rsp.
摘要翻译： 公开了功率半导体器件及其制造方法。 功率半导体器件具有PIP电容器和LDMOS晶体管，LDMOS晶体管具有与形成PIP电容器的上电极的过程中形成的第二和第三栅电极分离的第一和第三栅电极，因此可能 实现具有更高击穿电压的LDMOS和较低的Ron和Rsp，而无需额外的处理。 可以将不同于施加到第一栅电极的电压的漏极电压施加到第三栅电极，因此可以实现具有高击穿电压和低Ron和Rsp的LDMOS。
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公开(公告)号：US20060250049A1
公开(公告)日：2006-11-09
申请号：US11259199
申请日：2005-10-27
IPC分类号： H01L41/053
CPC分类号： H03H9/1085 , H01L2224/16225 , H03H9/059
摘要： The present invention provides a SAW device package used in filters, duplexers, etc., in particular, which simplifies sealing process for protecting the active area of a SAW device. The SAW device package comprises a wiring substrate, as a package base having connection patterns, having bare chip attaching means. A bare chip is flip-bonded and attached to the attaching means on the wiring substrate while maintaining the airtight condition. A resin molding part covers the top of the bare chip to seal the device. The invention facilitates maintaining an airtight condition of the active area which affects the operational characteristics of the device, and simplifies the manufacturing processes. Furthermore, the improved structure of the wiring substrate blocks the external moisture permeation, thereby enabling the device to better withstand the external changes.
摘要翻译： 本发明提供了一种特别用于滤波器，双工器等中的SAW器件封装，其简化了用于保护SAW器件的有源区域的密封工艺。 SAW器件封装包括布线衬底，作为具有连接图案的封装基座，具有裸芯片附接装置。 在保持气密状态的同时，将裸芯片翻转接合并附接到布线基板上的附接装置。 树脂成型部分覆盖裸芯片的顶部以密封装置。 本发明有助于维持影响装置的操作特性的活性区域的气密状态，并且简化了制造过程。 此外，布线基板的改进的结构阻止外部水分渗透，从而使得该装置能够更好地承受外部变化。
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29.发明申请公开(公告)号：US20060249824A1
公开(公告)日：2006-11-09
申请号：US11217465
申请日：2005-09-02
IPC分类号： H01L23/02
CPC分类号： H03H9/1085 , H01L24/97 , H01L2224/0554 , H01L2224/05568 , H01L2224/05573 , H01L2224/16 , H01L2224/48091 , H01L2224/97 , H01L2924/00014 , H01L2924/01005 , H01L2924/01006 , H01L2924/01019 , H01L2924/01033 , H01L2924/01078 , H01L2924/01079 , H01L2924/3025 , H03H3/08 , H03H9/059 , H03H9/1078 , H01L2224/81 , H01L2224/05599 , H01L2224/0555 , H01L2224/0556
摘要： Disclosed herein is a stack type surface acoustic wave package. The surface acoustic wave package comprises a first bare chip having a plurality of electrodes formed thereon, a second bare chip having a plurality of electrodes and via-holes formed thereon, a connecting portion electrically connecting the first bare chip to an upper surface of the second bare chip such that the electrodes of the first bare chip face the electrodes of the second bare chip, and a sealing member provided on the first and second bare chips to form an air-tight space on an operating surface between the first and second bare chips. The surface acoustic wave package can prevent deformation due to thermal impact from the outside during a packaging process, enhancing reliability of the product, minimizing the size of the product, and reducing manufacturing costs by reducing the number of components and material costs.
摘要翻译： 这里公开了一种堆叠型表面声波封装。 表面声波封装包括具有形成在其上的多个电极的第一裸芯片，具有形成在其上的多个电极和通孔的第二裸芯片，将第一裸芯片电连接到第二裸芯片的上表面的连接部分 裸芯片，使得第一裸芯片的电极面对第二裸芯片的电极;以及密封构件，设置在第一裸芯片和第二裸芯片上，以在第一和第二裸芯片之间的操作表面上形成气密空间 。 表面声波封装可以防止在包装过程中由于外界的热冲击而引起的变形，提高产品的可靠性，最小化产品尺寸，并通过减少部件数量和材料成本降低制造成本。
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公开(公告)号：US20060227076A1
公开(公告)日：2006-10-12
申请号：US11328180
申请日：2006-01-10
申请人： Nam Kim
发明人： Nam Kim
IPC分类号： G09G3/28
CPC分类号： G09G3/2022 , G09G3/2029 , G09G3/204 , G09G3/2927 , G09G2320/0238 , G09G2320/0247 , G09G2320/0266 , G09G2360/16
摘要： Disclosed are a plasma display panel, a plasma display apparatus and a driving apparatus and method of the plasma display panel. The plasma display apparatus comprises a plasma display panel comprising a scan electrode and a sustain electrode and a reset pulse controller for controlling a amplitude of reset pulse applied to the scan electrode in the reset period of at least one subfield according to a gray level.
摘要翻译： 公开了等离子体显示面板，等离子体显示装置以及等离子体显示面板的驱动装置和方法。 等离子体显示装置包括等离子体显示面板，其包括扫描电极和维持电极，以及复位脉冲控制器，用于根据灰度级控制在至少一个子场的复位周期中施加到扫描电极的复位脉冲的幅度。
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