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公开(公告)号:US6111145A
公开(公告)日:2000-08-29
申请号:US419221
申请日:1999-10-15
申请人: Eiji Kobayashi , Nobuto Koyama , Ikunoshin Kato , Kaoru Inami , Tetsuo Shiba
发明人: Eiji Kobayashi , Nobuto Koyama , Ikunoshin Kato , Kaoru Inami , Tetsuo Shiba
IPC分类号: C07C45/71 , C07C49/753 , C07C49/105 , A61K31/12
CPC分类号: C07C49/753 , C07C45/71
摘要: A cyclopentenone derivative represented by the following formula [I] or an optically active substance or a salt thereof. ##STR1## (In the formula, R.sub.1 and R.sub.2 are same or different and each of them is straight or branched alkyl group, straight or branched alkenyl group, aromatic group, aromatic-aliphatic group or H with a proviso that the case where R.sub.1 =R.sub.2 =H, or R.sub.1 =benzyl group and R.sub.2 =H is excluded.)
摘要翻译: 由下式[I]表示的环戊烯酮衍生物或光学活性物质或其盐。 (式中,R 1,R 2相同或不同,分别为直链或支链烷基,直链或支链烯基,芳香族基,芳香族 - 脂肪族基或H,条件是R1 = R2 = H ,或R 1 =苄基,并且R 2 = H被排除。
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公开(公告)号:US07422750B2
公开(公告)日:2008-09-09
申请号:US10408346
申请日:2003-04-08
IPC分类号: A61K36/02
CPC分类号: A23G3/42 , A21D2/18 , A23C9/152 , A23F3/405 , A23L2/52 , A23L7/109 , A23L13/426 , A23L21/15 , A23L29/256 , A23L33/105 , C07H5/10
摘要: Food or beverage where fucoidan which is derived from a fucoidan-containing substance is contained therein, added thereto and/or diluted therein. Food or beverage where fucoidan which is derived from a fucoidan-containing substance and where algins are reduced or eliminated, is contained therein. Apoptosis-inducing food or beverage where an effective amount of fucoidan having an apoptosis-inducing ability is contained therein.
摘要翻译: 含有含岩藻依聚糖的物质的岩藻依聚糖含有,添加和/或稀释的食品或饮料。 其中含有衍生自含岩藻依聚糖的物质并且其中还原或除去藻酸盐的岩藻依聚糖的食品或饮料。 其中含有有效量的具有凋亡诱导能力的岩藻依聚糖的诱导细胞凋亡的食物或饮料。
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公开(公告)号:US06277616B1
公开(公告)日:2001-08-21
申请号:US09517633
申请日:2000-03-03
申请人: Takeshi Sakai , Hitomi Kimura , Kaoru Kojima , Katsushige Ikai , Sumiko Akiyoshi , Yoshikuni Nakanishi , Ikunoshin Kato
发明人: Takeshi Sakai , Hitomi Kimura , Kaoru Kojima , Katsushige Ikai , Sumiko Akiyoshi , Yoshikuni Nakanishi , Ikunoshin Kato
IPC分类号: C12N924
CPC分类号: C12Y302/01044 , C07H1/00 , C07H3/06 , C07H5/10 , C12N9/2402 , C12N9/88 , C12P19/44 , C12R1/01 , Y10S435/822
摘要: An isolated endo-fucoidan-lyase is described. The enzyme acts on fucoidan, has a pH optimum from 6 to 10, and has an optimum pH from 30 to 40° C. The enzyme can be isolated from Flavobacterium sp. FERM BP-5402. The enzyme is used to obtain sugar compounds which are useful in the study on carbohydrates.
摘要翻译: 描述了分离的内切胶质细胞裂解酶。 该酶作用于岩藻依聚糖,最适pH为6至10,最适pH为30至40℃。酶可以从黄杆菌属中分离出来。 FERM BP-5402。 该酶用于获得在碳水化合物研究中有用的糖化合物。
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公开(公告)号:US07125984B2
公开(公告)日:2006-10-24
申请号:US10258133
申请日:2001-04-19
申请人: Takeshi Sakai , Kumiko Ishizuka , Kaoru Kojima , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
发明人: Takeshi Sakai , Kumiko Ishizuka , Kaoru Kojima , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
CPC分类号: C12Y302/01139 , C08B37/00 , C08B37/006 , C12N9/2402 , C12P19/14 , C12R1/01 , C12Y302/01044
摘要: Three enzymes degrading sulfated glucuronofucan; processes for producing these enzymes; activators for these enzymes; glucuronofucan sulfate and degradation products thereof; and a novel microorganism.
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公开(公告)号:US20050255564A1
公开(公告)日:2005-11-17
申请号:US10500834
申请日:2003-01-17
申请人: Takeshi Sakai , Hitomi Amarume , Katsushige Ikai , Ikunoshin Kato
发明人: Takeshi Sakai , Hitomi Amarume , Katsushige Ikai , Ikunoshin Kato
IPC分类号: C07H11/00 , C08B37/00 , C12N9/18 , C12N9/24 , C12N9/26 , C12P19/04 , C12P19/14 , C12P19/20 , C08B35/02
CPC分类号: C12N9/2408 , C07H11/00 , C08B37/0006 , C12N9/18 , C12N9/2402 , C12P19/04 , C12P19/14 , C12P19/20 , C12Y302/01051
摘要: An enzyme capable of degrading sulfated fucan originating in a brown alga of Fucales which is useful in sugar chain engineering; a process for producing this enzyme; an oligosaccharide obtained by treating sulfated fucan with the enzyme; and production thereof.
摘要翻译: 能够降解起源于Fucales褐藻的硫酸化岩藻糖的酶,其可用于糖链工程; 一种生产该酶的方法; 通过用该酶处理硫酸化的岩藻糖获得的寡糖; 及其生产。
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公开(公告)号:US06927289B2
公开(公告)日:2005-08-09
申请号:US10694352
申请日:2003-10-28
申请人: Takeshi Sakai , Hitomi Amarume , Takashi Kawai , Kaoru Kojima , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
发明人: Takeshi Sakai , Hitomi Amarume , Takashi Kawai , Kaoru Kojima , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
CPC分类号: C08B37/006
摘要: A smaller molecule obtainable by allowing a sulfated fucan-digesting enzyme which digests a novel sulfated polysaccharide derived from an alga belonging to Laminariales to act on a sulfated fucan, and a method for producing the same.
摘要翻译: 通过使来自属于层状藻酸盐的藻类的新型硫酸化多糖消化的硫酸化的岩藻糖消化酶作用于硫酸化的岩藻石上的小分子及其制造方法。
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公开(公告)号:US06720419B2
公开(公告)日:2004-04-13
申请号:US10278942
申请日:2002-10-24
申请人: Takeshi Sakai , Hitomi Amarume , Takashi Kawai , Kaoru Kojima , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
发明人: Takeshi Sakai , Hitomi Amarume , Takashi Kawai , Kaoru Kojima , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
IPC分类号: C08B3700
CPC分类号: C08B37/006
摘要: A smaller molecule obtainable by allowing a sulfated fucan-digesting enzyme which digests a novel sulfated polysaccharide derived from an alga belonging to Laminariales to act on a sulfated fucan, and a method for producing the same.
摘要翻译: 通过使来自属于层状藻酸盐的藻类的新型硫酸化多糖消化的硫酸化的岩藻糖消化酶作用于硫酸化的岩藻石上的小分子及其制造方法。
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公开(公告)号:US06590097B1
公开(公告)日:2003-07-08
申请号:US09913599
申请日:2001-08-16
申请人: Takeshi Sakai , Hitomi Kimura , Kaoru Kojima , Kaoru Katayama , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
发明人: Takeshi Sakai , Hitomi Kimura , Kaoru Kojima , Kaoru Katayama , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
IPC分类号: C08B3700
CPC分类号: C08B37/006 , C12N9/2402 , C12P19/04
摘要: Sulfated fucogalactan or its salt useful as a reagent for sugar chain engineering or an HGF-production inducer; a degraded product or its salt obtained by treating the sulfated fucogalactan with a sulfated fucogalactan digesting enzyme; the sulfated fucogalactan digesting enzyme useful in sugar chain engineering; a process for producing the degraded product by treating sulfated fucogalactan or its salt with the above enzyme; and a process for producing the sulfated fucogalactan digesting enzyme.
摘要翻译: 硫酸化的赖卡半乳糖或其盐可用作糖链工程或HGF生产诱导剂的试剂; 通过用硫酸化的福卡美凝乳消化酶处理硫酸化的核糖乳聚糖获得的降解产物或其盐; 用于糖链工程的硫酸岩藻糖半乳糖消化酶; 通过用上述酶处理硫酸化的赖氨酰半乳糖或其盐来生产降解产物的方法; 以及生产硫酸化的赖卡半乳聚糖消化酶的方法。
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公开(公告)号:US6054577A
公开(公告)日:2000-04-25
申请号:US930002
申请日:1997-09-26
申请人: Takeshi Sakai , Hitomi Kimura , Kaoru Kojima , Katsushige Ikai , Sumiko Akiyoshi , Yoshikuni Nakanishi , Ikunoshin Kato
发明人: Takeshi Sakai , Hitomi Kimura , Kaoru Kojima , Katsushige Ikai , Sumiko Akiyoshi , Yoshikuni Nakanishi , Ikunoshin Kato
IPC分类号: C07H11/00 , C07H1/00 , C07H3/06 , C07H5/10 , C08B37/00 , C12N1/20 , C12N9/24 , C12N9/88 , C12P19/14 , C12P19/44 , C07H13/02 , C12P19/04
CPC分类号: C12Y302/01044 , C07H1/00 , C07H3/06 , C07H5/10 , C12N9/2402 , C12N9/88 , C12P19/44 , C12R1/01 , Y10S435/822
摘要: A novel endo-fucoidan-lyase and a novel microorganism useful in the production of sugar compounds. Sugar compounds represented by the following general formula (1), wherein at least one of alcoholic hydroxyl group has been sulfated, or salts thereof: ##STR1## wherein Y represents hydrogen or a group represented by the following formula (2). ##STR2##
摘要翻译: PCT No.PCT / JP96 / 01080 Sec。 371日期:1997年9月26日 102(e)1997年9月26日PCT PCT 1996年4月22日PCT公布。 公开号WO96 / 34004 日期1996年10月31日一种新型内切 - 岩藻依聚糖裂解酶和用于生产糖化合物的新型微生物。 由以下通式(1)表示的糖化合物,其中醇羟基中的至少一个已被硫酸化,或其盐:其中Y表示氢或由下式(2)表示的基团。
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公开(公告)号:US20060166335A1
公开(公告)日:2006-07-27
申请号:US11373989
申请日:2006-03-14
申请人: Takeshi Sakai , Kumiko Ishizuka , Kaoru Kojima , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
发明人: Takeshi Sakai , Kumiko Ishizuka , Kaoru Kojima , Kazuo Shimanaka , Katsushige Ikai , Ikunoshin Kato
CPC分类号: C12Y302/01139 , C08B37/00 , C08B37/006 , C12N9/2402 , C12P19/14 , C12R1/01 , C12Y302/01044
摘要: Three enzymes degrading sulfated glucuronofucan; processes for producing these enzymes; activators for these enzymes; glucuronofucan sulfate and degradation products thereof; and a novel microorganism.
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