公开(公告)号：US08236238B2

公开(公告)日：2012-08-07

申请号：US12357224

申请日：2009-01-21

申请人： Scott Albert Uhland ,  Eric Peeters ,  Francisco E. Torres ,  Philipp Helmut Schmaelzle

发明人： Scott Albert Uhland ,  Eric Peeters ,  Francisco E. Torres ,  Philipp Helmut Schmaelzle

IPC分类号： A61L2/00

CPC分类号： A61N7/00 ,  A61F7/00 ,  Y10S588/90

摘要： A drug deactivation system according to some embodiments includes at least one drug-retaining region of a drug delivery device and at least one energy source coupled to the at least one drug-retaining region. The at least one drug-retaining region may be configured to retain a drug. The at least one energy source may be configured to transmit energy to the drug. The drug is capable of being rendered ineffective in the presence of the transmitted energy.

摘要翻译： 根据一些实施方案的药物失活系统包括药物递送装置的至少一个药物保持区域和与至少一个药物保持区域耦合的至少一个能量源。 至少一个药物保持区域可以被配置为保留药物。 所述至少一个能量源可以被配置为向所述药物传输能量。 药物能够在传播能量的存在下变得无效。

公开(公告)号：US08211617B2

公开(公告)日：2012-07-03

申请号：US12542171

申请日：2009-08-17

申请人： Norine E. Chang ,  C. Wayne Jaeger ,  Scott Jong Ho Limb ,  Eric J. Shrader ,  Francisco E. Torres ,  Kris Schmidt

发明人： Norine E. Chang ,  C. Wayne Jaeger ,  Scott Jong Ho Limb ,  Eric J. Shrader ,  Francisco E. Torres ,  Kris Schmidt

IPC分类号： G03F7/00 ,  G03F7/26 ,  G03F7/40 ,  G04F7/004

CPC分类号： G03F7/2018 ,  C09D11/30 ,  C09D11/36

摘要： A printed mask derived from a composition comprised of at least one compound including at least one alkaline-hydrolyzable group, and at least one compound including at least one ethylene oxide group. The printed mask is removable using an alkaline solution in about 30 seconds or less.

摘要翻译： 由包含至少一种包含至少一个碱可水解基团的化合物和至少一种包含至少一个环氧乙烷基团的化合物组成的组合物的印刷掩模。 印刷的面罩可在约30秒或更短时间内使用碱性溶液除去。

公开(公告)号：US07790111B2

公开(公告)日：2010-09-07

申请号：US11017394

申请日：2004-12-20

申请人： Francisco E. Torres ,  Jonathan S. Daniels ,  Meng H. Lean

发明人： Francisco E. Torres ,  Jonathan S. Daniels ,  Meng H. Lean

IPC分类号： G01N27/00 ,  G01N13/04 ,  G01N33/00

CPC分类号： B01L3/505 ,  G01N13/04 ,  Y10S436/807

摘要： A method and apparatus for measuring the presence or absence of interaction between at least a first and second material of interest by measuring osmotic pressure changes in an osmotic cell. Changes in osmotic pressure are determined by measuring the amount of compression exhibited by a compressible, semi-permeable material positioned in the cell.

公开(公告)号：US20100185038A1

公开(公告)日：2010-07-22

申请号：US12357108

申请日：2009-01-21

申请人： Scott Albert Uhland ,  Eric Peeters ,  Francisco E. Torres ,  Philipp Helmut Schmaelzle

发明人： Scott Albert Uhland ,  Eric Peeters ,  Francisco E. Torres ,  Philipp Helmut Schmaelzle

IPC分类号： A62D3/30

CPC分类号： A61K9/0002

摘要： A drug deactivation system according to some embodiments includes at least one degradable capsule exposed to at least one drug-retaining region of a drug delivery device and an agent. The agent is configured to render a drug ineffective upon degradation of the at least one capsule. The at least one drug-retaining region is configured to retain one of the drug and the agent and the at least one capsule is configured to retain the other of the drug and the agent.

摘要翻译： 根据一些实施方案的药物失活系统包括暴露于药物递送装置和药剂的至少一个药物保持区域的至少一个可降解胶囊。 该药剂配置成使药物对至少一个胶囊的降解无效。 所述至少一个药物保持区被配置为保留药物和药剂中的一种，并且所述至少一个胶囊被配置为保留药物和药剂中的另一个。

公开(公告)号：US07615375B2

公开(公告)日：2009-11-10

申请号：US10739852

申请日：2003-12-18

申请人： Francisco E. Torres ,  Karl Littau ,  Eric Shrader

发明人： Francisco E. Torres ,  Karl Littau ,  Eric Shrader

IPC分类号： G01N7/00

CPC分类号： G01N13/04 ,  G01N7/10 ,  Y10T436/11

摘要： A method and apparatus for measuring the presence or absence of reaction between a first and second material of interest by measuring osmotic pressure changes in a reaction cell. The reaction cell is capable of measuring the small changes in pressure that occur due to osmotic pressure shifts during a catalytic or binding reaction at species concentrations down to approximately 10−7 M.

摘要翻译： 一种通过测量反应池中的渗透压变化来测量感兴趣的第一和第二材料之间是否存在反应的方法和装置。 反应池能够测量在催化或结合反应期间在物质浓度低至约10 -7 M时由于渗透压移动而发生的压力变化小。

公开(公告)号：US20090260425A1

公开(公告)日：2009-10-22

申请号：US12493668

申请日：2009-06-29

申请人： Francisco E. Torres ,  Eric Shrader ,  Karl Littau

发明人： Francisco E. Torres ,  Eric Shrader ,  Karl Littau

IPC分类号： G01N13/04

CPC分类号： G01N13/04 ,  Y10S436/807

摘要： An apparatus and system for measuring the presence or absence of reaction between a first and second material of interest by measuring osmotic pressure changes of reaction detector. The reaction detector is capable of measuring the small changes in pressure that occur due to osmotic pressure shifts during a catalytic or binding reaction at species concentrations down to approximately 10−7 M.

摘要翻译： 一种用于通过测量反应检测器的渗透压变化来测量感兴趣的第一和第二材料之间是否存在反应的装置和系统。 反应检测器能够测量在催化或结合反应期间由于渗透压变化而产生的压力变化小于约10-7M的物质浓度。

公开(公告)号：US07553669B2

公开(公告)日：2009-06-30

申请号：US10739853

申请日：2003-12-18

申请人： Francisco E. Torres ,  Eric Shrader ,  Karl Littau

发明人： Francisco E. Torres ,  Eric Shrader ,  Karl Littau

IPC分类号： G01N33/00 ,  G01N7/00 ,  C12Q1/68

CPC分类号： G01N13/04 ,  Y10S436/807

摘要： A method and apparatus for measuring the presence or absence of reaction between a first and second material of interest by measuring osmotic pressure changes of reaction detector. The reaction detector is capable of measuring the small changes in pressure that occur due to osmotic pressure shifts during a catalytic or binding reaction at species concentrations down to approximately 10−7 M.

摘要翻译： 通过测量反应检测器的渗透压变化来测量感兴趣的第一和第二材料之间是否存在反应的方法和装置。 反应检测器能够测量在催化或结合反应期间由于渗透压变化而产生的压力变化小于约10-7M的物质浓度。

公开(公告)号：US07126134B2

公开(公告)日：2006-10-24

申请号：US10921556

申请日：2004-08-19

申请人： Meng H. Lean ,  Francisco E. Torres ,  Huangpin Ben Hsieh ,  Armin R. Völkel ,  Bryan Preas ,  Scott A. Elrod ,  John S. Fitch ,  Richard H. Bruce

发明人： Meng H. Lean ,  Francisco E. Torres ,  Huangpin Ben Hsieh ,  Armin R. Völkel ,  Bryan Preas ,  Scott A. Elrod ,  John S. Fitch ,  Richard H. Bruce

IPC分类号： G21K5/10

CPC分类号： B03C1/253

摘要： A sample manipulator that utilizes electrostatic traveling waves to selectively displace one or more samples deposited on its face is disclosed. The sample manipulator enables an operator to perform a wide variety of processes upon the deposited samples. Also disclosed are strategies for separating two or more samples, focusing a sample, and passing a reagent through a sample, all conducted on the face of the sample manipulator.

公开(公告)号：US5650255A

公开(公告)日：1997-07-22

申请号：US706880

申请日：1996-09-03

申请人： T. Hwee Ng ,  Arthur Helbrecht ,  Raj D. Patel ,  Grazyna E. Kmiecik-Lawrynowicz ,  David Kurceba ,  Francisco E. Torres ,  David J. Sanders

发明人： T. Hwee Ng ,  Arthur Helbrecht ,  Raj D. Patel ,  Grazyna E. Kmiecik-Lawrynowicz ,  David Kurceba ,  Francisco E. Torres ,  David J. Sanders

IPC分类号： G03G9/08 ,  G03G9/087

CPC分类号： G03G9/0804 ,  G03G9/0819

摘要： An in situ chemical process for the preparation of toner comprised of(i) the provision of a latex, which latex is comprised of polymeric resin particles, an ionic surfactant and a nonionic surfactant;(ii) providing a pigment dispersion, which dispersion is comprised of a pigment solution, a counterionic surfactant with a charge polarity of opposite sign to that of said ionic surfactant, and optionally a charge control agent;(iii) mixing said pigment dispersion with said latex with a stirrer equipped with an impeller, stirring at speeds of from about 100 to about 900 rpm for a period of from about 10 minutes to about 150 minutes;(iv) heating the above resulting blend of latex and pigment mixture to a temperature below about the glass transition temperature (Tg) of the resin to form electrostatically bound toner size aggregates;(v) adding further aqueous ionic surfactant or stabilizer in the range amount of from about 0.1 percent to 5 percent by weight of reactants to stabilize the above electrostatically bound toner size aggregates;(vi) heating said electrostatically bound toner sized aggregates above about the Tg of the resin to form toner size particles containing pigment, resin and optionally a charge control agent;(vii) optionally isolating said toner, optionally washing with water; and optionally(viii) drying said toner.

摘要翻译： 用于制备调色剂的原位化学方法包括（i）提供胶乳，所述胶乳由聚合树脂颗粒，离子表面活性剂和非离子表面活性剂组成; （ii）提供颜料分散体，该分散体由颜料溶液，具有与所述离子表面活性剂相反的电荷极性的反离子表面活性剂和任选的电荷控制剂组成; （iii）将所述颜料分散体与所述胶乳混合，配备有叶轮的搅拌器，以约100至约900rpm的速度搅拌约10分钟至约150分钟; （iv）将上述胶乳和颜料混合物的混合物加热到低于树脂的玻璃化转变温度（Tg）的温度，以形成静电结合的调色剂尺寸聚集体; （v）加入其量为约0.1％至5％（重量）的反应物的水性离子表面活性剂或稳定剂，以稳定上述静电结合的调色剂尺寸聚集体; （vi）将所述静电结合的调色剂大小的聚集体加热到树脂的Tg附近，以形成含有颜料，树脂和任选的电荷控制剂的调色剂尺寸颗粒; （vii）任选地分离所述调色剂，任选地用水洗涤; 和（viii）干燥所述调色剂。

公开(公告)号：US09161714B2

公开(公告)日：2015-10-20

申请号：US12195942

申请日：2008-08-21

申请人： Joerg Martini ,  Richard H. Bruce ,  Francisco E. Torres ,  Peter Kiesel ,  Michael I. Recht ,  Jeffrey N. Roe

发明人： Joerg Martini ,  Richard H. Bruce ,  Francisco E. Torres ,  Peter Kiesel ,  Michael I. Recht ,  Jeffrey N. Roe

IPC分类号： A61B5/00 ,  A61B5/1459 ,  A61B5/145 ,  G01N21/33 ,  G01N21/359

CPC分类号： A61B5/1459 ,  A61B5/0031 ,  A61B5/14532 ,  G01N21/33 ,  G01N21/359

摘要： A system and method is provided for detecting concentration of an analyte in a fluid. A first container includes (i) an optical cavity detection region, (ii) a reservoir for one or more modifiers of one or more optical properties of the optical cavity detection region, and (iii) a set of one or more bounding regions through which objects in the fluid can transfer into the container. The optical cavity detection region and the reservoir define separate areas of the first container. The movement of the one or more modifiers between the reservoir and the optical cavity detection region is responsive to changes in concentration of the analyte. A second container includes an optical cavity detection region, and a set of one or more bounding regions through which objects in the fluid can transfer into the container. Also provided are optical components for guiding light into the optical cavity detection regions of the first and second containers.

摘要翻译： 提供了用于检测流体中分析物的浓度的系统和方法。 第一容器包括（i）光腔检测区域，（ii）用于一个或多个光腔检测区域的一个或多个光学特性的修改器的储存器，以及（iii）一组或多个边界区域， 流体中的物体可以转移到容器中。 光腔检测区域和储存器限定第一容器的分开的区域。 储存器和光腔检测区域之间的一个或多个改性剂的运动响应于分析物浓度的变化。 第二容器包括光学腔检测区域和一组一个或多个界限区域，流体中的物体可通过该区域传送到容器中。 还提供了用于将光引导到第一和第二容器的光学腔检测区域中的光学部件。