公开(公告)号：US20140038473A1

公开(公告)日：2014-02-06

申请号：US14112756

申请日：2012-04-17

申请人： Hiroshi Kojima ,  Takashi Tsukamoto

发明人： Hiroshi Kojima ,  Takashi Tsukamoto

IPC分类号： H01R13/18

CPC分类号： H01R13/18 ,  H01R13/111 ,  H01R43/16

摘要： The present invention provides a terminal fitting that ensures constant contact load of an inserter that is inserted into an electrical contact by making uniform the amounts of displacement among a plurality of resilient pieces constituting the electrical contact. A terminal fitting includes a cylindrical electrical contact portion obtained by making the both ends of the conductive metal plate close to each other and joined to each other. The electrical contact portion includes a plurality of slits extending in a cylinder-length direction N and provided at intervals in the circumferential direction of the electrical contact portion. The slits provided farthest away from the joining portion at the both ends of the metal plate have a size in the cylinder-length direction N larger than those of the other slits.

摘要翻译： 本发明提供了一种端子接头，其通过使构成电接触件的多个弹性件之间的位移量均匀地确保插入到电接触件中的恒定的接触负载。 端子接头包括通过使导电金属板的两端彼此靠近并且彼此接合而获得的圆柱形电接触部分。 电接触部分包括在气缸长度方向N上延伸并沿电接触部分的圆周方向间隔设置的多个狭缝。 在金属板的两端处距离接合部分最远的狭缝具有比其他狭缝更大的气缸长度方向N的尺寸。

公开(公告)号：US20130109643A1

公开(公告)日：2013-05-02

申请号：US13697097

申请日：2011-05-10

申请人： Gregory Joseph Riggins ,  Meghan Joyce Seltzer ,  Takashi Tsukamoto ,  Chi Van Dang ,  Ashkan Emadi

发明人： Gregory Joseph Riggins ,  Meghan Joyce Seltzer ,  Takashi Tsukamoto ,  Chi Van Dang ,  Ashkan Emadi

IPC分类号： A61K31/433 ,  A61K31/704

CPC分类号： A61K31/433 ,  A61K31/704

摘要： Methods for treating a cancer having a mutant isocitrate dehydrogenase (IDH), including, but not limited to, a malignant low-grade glioma, a secondary glioblastoma, a transforming myeloproliferative disorder (tMPD), and an acute myelogenous leukemia (AML), with a glutaminase inhibitor, including, bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES), are disclosed.

摘要翻译： 用于治疗具有突变异柠檬酸脱氢酶（IDH）的癌症的方法，包括但不限于恶性低级胶质瘤，继发性胶质母细胞瘤，转化性骨髓增生性疾病（tMPD）和急性骨髓性白血病（AML），其具有 包括二-2-（5-苯基乙酰氨基-1,2,4-噻二唑-2-基）乙基硫醚（BPTES）的谷氨酰胺酶抑制剂。

公开(公告)号：US20110108680A1

公开(公告)日：2011-05-12

申请号：US13000584

申请日：2009-06-19

申请人： Mitsuhiro Matsumoto ,  Hajime Katou ,  Takashi Tsukamoto

发明人： Mitsuhiro Matsumoto ,  Hajime Katou ,  Takashi Tsukamoto

IPC分类号： F16L3/12

CPC分类号： F16L3/1222 ,  F16L33/03 ,  H02G3/30 ,  Y10T24/1457

摘要： Provided is an electrical wire fixing member that can be assembled in a simple manner with the reduced number of parts, and is capable of obtaining a sufficient lap amount, which can further reduce the number of parts. In an electrical wire fixing band 1 that secures an electrical wire 20, the first flange 3 is provided at a tip of the one end 2a of the body 2 in a shape of a ring, with both ends overlapping with each other along the circumference of the body. A second flange 4 is provided at the other end 2b. A protruding piece 5 is provided in a direction where the other end 2b becomes more distant from the one end 2a. A locking piece 6 is provided closer to the one end than the tip of the other end 2b is.

摘要翻译： 本发明提供一种电线固定构件，其能够以简单的方式组装，并且能够获得足够的搭接量，从而可以进一步减少零件数量。 在固定电线20的电线固定带1中，第一凸缘3设置在主体2的一端2a的尖端处的环形状，两端彼此沿着圆周方向重叠 身体。 第二凸缘4设置在另一端2b处。 在另一端2b变得远离一端2a的方向上设置有突出片5。 锁定片6设置成比另一端2b的前端更靠近一端。

公开(公告)号：US20100191934A1

公开(公告)日：2010-07-29

申请号：US12726694

申请日：2010-03-18

申请人： Shumpei Kawasaki ,  Eiji Sakakibara ,  Kaoru Fukada ,  Takanaga Yamazaki ,  Yasushi Akao ,  Shiro Baba ,  Toshimasa Kihara ,  Keiichi Kurakazu ,  Takashi Tsukamoto ,  Shigeki Masumura ,  Yasuhiro Tawara ,  Yugo Kashiwagi ,  Shuya Fujita ,  Katsuhiko Ishida ,  Noriko Sawa ,  Yoichi Asano ,  Hideaki Chaki ,  Tadahiko Sugawara ,  Masahiro Kainaga ,  Kouki Noguchi ,  Mitsuru Watabe

发明人： Shumpei Kawasaki ,  Eiji Sakakibara ,  Kaoru Fukada ,  Takanaga Yamazaki ,  Yasushi Akao ,  Shiro Baba ,  Toshimasa Kihara ,  Keiichi Kurakazu ,  Takashi Tsukamoto ,  Shigeki Masumura ,  Yasuhiro Tawara ,  Yugo Kashiwagi ,  Shuya Fujita ,  Katsuhiko Ishida ,  Noriko Sawa ,  Yoichi Asano ,  Hideaki Chaki ,  Tadahiko Sugawara ,  Masahiro Kainaga ,  Kouki Noguchi ,  Mitsuru Watabe

IPC分类号： G06F9/38 ,  G06F12/08 ,  G06F9/30 ,  G06F15/76 ,  G06F9/06

CPC分类号： G06F7/535 ,  G06F9/30 ,  G06F9/3001 ,  G06F9/30112 ,  G06F9/3013 ,  G06F9/30145 ,  G06F9/30149 ,  G06F9/3016 ,  G06F9/30163 ,  G06F9/30167 ,  G06F9/30181 ,  G06F9/30189 ,  G06F9/322 ,  G06F9/324 ,  G06F9/3557 ,  G06F9/3802 ,  G06F9/3814 ,  G06F9/3836 ,  G06F9/3857 ,  G06F9/3859 ,  G06F9/3867 ,  G06F2207/5352

摘要： Herein disclosed is a microcomputer MCU adopting the general purpose register method. The microcomputer is enabled to have a small program capacity or a high program memory using efficiency and a low system cost, while enjoying the advantage of simplification of the instruction decoding as in the RISC machine having a fixed length instruction format of the prior art, by adopting a fixed length instruction format having a power of 2 but a smaller bit number than that of the maximum data word length fed to instruction execution means. And, the control of the coded division is executed by noting the code bits.

摘要翻译： 这里公开了采用通用寄存器方法的微计算机MCU。 微型计算机能够使用效率低且系统成本低的程序容量小或高程序存储器，同时具有简化指令解码的优点，如具有现有技术的固定长度指令格式的RISC机器，通过 采用固定长度指令格式，其具有功率2但是比馈送到指令执行装置的最大数据字长度的位数更小的位数。 并且，通过注意码位来执行编码除法的控制。

公开(公告)号：US20090137521A1

公开(公告)日：2009-05-28

申请号：US12252961

申请日：2008-10-16

申请人： Gregory S. Hamilton ,  Takashi Tsukamoto ,  Dana V. Ferraris ,  Bridget Duvall ,  Rena Lapidus

发明人： Gregory S. Hamilton ,  Takashi Tsukamoto ,  Dana V. Ferraris ,  Bridget Duvall ,  Rena Lapidus

IPC分类号： A61K31/7068 ,  C07H19/073 ,  C07H19/12 ,  A61K31/706 ,  A61P35/00

CPC分类号： C07H19/06 ,  A61K31/7068 ,  A61K45/06 ,  C07B2200/13 ,  C07H1/00 ,  C07H19/04 ,  C07H19/073

摘要： The present invention provides certain tetrahydrouridine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of making and using such compounds.

摘要翻译： 本发明提供某些四氢尿苷衍生物化合物，包含这些化合物的药物组合物和试剂盒，以及制备和使用这些化合物的方法。

公开(公告)号：US20090023345A1

公开(公告)日：2009-01-22

申请号：US11662501

申请日：2005-09-12

申请人： Mitsuhiro Matsumoto ,  Hirotaka Fukushima ,  Takashi Tsukamoto ,  Kenjiro Shiba ,  Tomoyuki Watanabe ,  Takashi Okamoto

发明人： Mitsuhiro Matsumoto ,  Hirotaka Fukushima ,  Takashi Tsukamoto ,  Kenjiro Shiba ,  Tomoyuki Watanabe ,  Takashi Okamoto

IPC分类号： H01R9/22

CPC分类号： H02M7/003 ,  H01R13/42 ,  H01R25/162 ,  H01R29/00 ,  H01R31/065

摘要： An inverter (apparatus), to which two motors are connected, or a connecting structure of the inverter and the motors is made compact. A direct mounting connector to be directly mounted on an apparatus, includes: six independent busbars 21-26 for connecting the apparatus to two auxiliary machines for three-phase alternating current; two first terminal parts 11, 12 of U-pole, two first terminal parts 13, 14 of V-pole and two first terminal parts 15, 16 of W-pole of three-phase alternating current, altogether the six first terminal parts 11-16 being connected to the apparatus and formed at first ends of the respective six busbars 21-26, the two first terminal parts of the same pole are arranged adjacently to each other; and two sets 31-33 and 34-36, each set of which consists of a second terminal part of U-pole, a second terminal part of V-pole and a second terminal part of W-pole, altogether the six second terminal parts being connected to the two auxiliary machines and formed at second ends of the respective six busbars, the two sets being arranged adjacently to each other having a distance therebetween. The busbars 22, 25 include extended parts 22c, 25c extending between the two sets 31-33, 34-36 of the second terminal parts. The busbars 21-26 are molded in an insulating resin part.

摘要翻译： 连接有两个电动机的逆变器（装置）或逆变器与电动机的连接结构紧凑。 直接安装在设备上的直接安装连接器包括：六个独立的母线21-26，用于将设备连接到两个用于三相交流的辅助机器; U极的两个第一端子部分11,12，V极的两个第一端子部分13,14，以及三相交流电的W极的两个第一端子部分15,16，总共有六个第一端子部分11- 16连接到装置并形成在相应的六个汇流条21-26的第一端，同一极的两个第一端子部彼此相邻布置; 和两组31-33和34-36，每组由U极的第二端子部分，V极的第二端子部分和W极的第二端子部分组成，共六个第二端子部分 连接到两个辅助机器并且形成在相应的六个汇流条的第二端处，两组彼此相邻设置，其间具有一定距离。 母线22,25包括在第二端子部件的两组31-33,34-36之间延伸的延伸部分22c，25c。 母线21-26被模制在绝缘树脂部分中。

公开(公告)号：US07077676B2

公开(公告)日：2006-07-18

申请号：US11230741

申请日：2005-09-21

申请人： Mitsuhiro Matsumoto ,  Hirotaka Fukushima ,  Takashi Tsukamoto

发明人： Mitsuhiro Matsumoto ,  Hirotaka Fukushima ,  Takashi Tsukamoto

IPC分类号： H01R13/52

CPC分类号： H01R13/521 ,  H01R13/5205 ,  H01R13/5221

摘要： A male tab terminal has an O-ring mounting portion formed between its wire connection portion and its electrical contact portion, and this O-ring mounting portion is surrounded by an opening peripheral surface of an O-ring receiving step portion of a female connector housing which defines an opening of a male terminal receiving chamber. An O-ring, mounted on the O-ring mounting portion of the male tab terminal, is held in intimate contact with an outer peripheral surface of the O-ring mounting portion over an entire periphery thereof, and also is held in intimate contact with the opening peripheral surface of the O-ring receiving step portion over an entire periphery thereof. When a female connector and a male connector are fitted together, the O-ring is directly clamped between the female connector housing and a male connector housing in a direction of fitting of the female and male connectors, and is pressed by the two connector housings.

公开(公告)号：US20060063412A1

公开(公告)日：2006-03-23

申请号：US11230741

申请日：2005-09-21

申请人： Mitsuhiro Matsumoto ,  Hirotaka Fukushima ,  Takashi Tsukamoto

发明人： Mitsuhiro Matsumoto ,  Hirotaka Fukushima ,  Takashi Tsukamoto

IPC分类号： H01R13/52

CPC分类号： H01R13/521 ,  H01R13/5205 ,  H01R13/5221

摘要： A male tab terminal has an O-ring mounting portion formed between its wire connection portion and its electrical contact portion, and this O-ring mounting portion is surrounded by an opening peripheral surface of an O-ring receiving step portion of a female connector housing which defines an opening of a male terminal receiving chamber. An O-ring, mounted on the O-ring mounting portion of the male tab terminal, is held in intimate contact with an outer peripheral surface of the O-ring mounting portion over an entire periphery thereof, and also is held in intimate contact with the opening peripheral surface of the O-ring receiving step portion over an entire periphery thereof. When a female connector and a male connector are fitted together, the O-ring is directly clamped between the female connector housing and a male connector housing in a direction of fitting of the female and male connectors, and is pressed by the two connector housings.

摘要翻译： 公接头端子具有形成在其导线连接部分和其电接触部分之间的O形环安装部分，并且该O形环安装部分被阴连接器壳体的O形环接收台阶部分的开口外周表面包围 其限定了公端子接收室的开口。 安装在公接头端子的O形环安装部上的O形环与O形环安装部的外周面在其整个外周保持紧密接触，并且还与 O形环接收台阶部的开口周面在其整个周边。 当阴连接器和阳连接器装配在一起时，O形环直接夹在阴连接器壳体和阳连接器壳体之间，并且在阴连接器和阳连接器的装配方向上被两个连接器壳体按压。

公开(公告)号：US06996700B2

公开(公告)日：2006-02-07

申请号：US10011807

申请日：2001-12-11

申请人： Shumpei Kawasaki ,  Eiji Sakakibara ,  Kaoru Fukada ,  Takanaga Yamazaki ,  Yasushi Akao ,  Shiro Baba ,  Toshimasa Kihara ,  Keiichi Kurakazu ,  Takashi Tsukamoto ,  Shigeki Masumura ,  Yasuhiro Tawara ,  Yugo Kashiwagi ,  Shuya Fujita ,  Katsuhiko Ishida ,  Noriko Sawa ,  Yoichi Asano ,  Hideaki Chaki ,  Tadahiko Sugawara ,  Masahiro Kainaga ,  Kouki Noguchi ,  Mitsuru Watabe

发明人： Shumpei Kawasaki ,  Eiji Sakakibara ,  Kaoru Fukada ,  Takanaga Yamazaki ,  Yasushi Akao ,  Shiro Baba ,  Toshimasa Kihara ,  Keiichi Kurakazu ,  Takashi Tsukamoto ,  Shigeki Masumura ,  Yasuhiro Tawara ,  Yugo Kashiwagi ,  Shuya Fujita ,  Katsuhiko Ishida ,  Noriko Sawa ,  Yoichi Asano ,  Hideaki Chaki ,  Tadahiko Sugawara ,  Masahiro Kainaga ,  Kouki Noguchi ,  Mitsuru Watabe

IPC分类号： G06F9/32

CPC分类号： G06F7/535 ,  G06F9/30 ,  G06F9/3001 ,  G06F9/30112 ,  G06F9/3013 ,  G06F9/30145 ,  G06F9/30149 ,  G06F9/3016 ,  G06F9/30163 ,  G06F9/30167 ,  G06F9/30181 ,  G06F9/30189 ,  G06F9/322 ,  G06F9/324 ,  G06F9/3557 ,  G06F9/3802 ,  G06F9/3814 ,  G06F9/3836 ,  G06F9/3857 ,  G06F9/3859 ,  G06F9/3867 ,  G06F2207/5352

摘要： Herein disclosed is a microcomputer MCU adopting the general purpose register method. The microcomputer is enabled to have a small program capacity or a high program memory using efficiency and a low system cost, while enjoying the advantage of simplification of the instruction decoding as in the RISC machine having a fixed length instruction format of the prior art, by adopting a fixed length instruction format having a power of 2 but a smaller bit number than that of the maximum data word length fed to instruction execution means. And, the control of the coded division is executed by noting the code bits.

公开(公告)号：US06992215B2

公开(公告)日：2006-01-31

申请号：US10959199

申请日：2004-10-07

申请人： Takashi Tsukamoto ,  Pavel Majer ,  Doris Stoermer ,  Barbara S. Slusher

发明人： Takashi Tsukamoto ,  Pavel Majer ,  Doris Stoermer ,  Barbara S. Slusher

IPC分类号： C07C321/06 ,  C07C323/04 ,  C07C317/14 ,  A61K31/095

CPC分类号： C07C323/56 ,  C07C323/52 ,  C07C323/58 ,  C07C323/59 ,  C07C323/60 ,  C07C323/62 ,  C07C323/65

摘要： This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-β activity, inhibiting angiogenesis, and treating glutamate abnormalities, diabetic neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.