公开(公告)号：US5470751A

公开(公告)日：1995-11-28

申请号：US199339

申请日：1994-02-18

申请人： Takashi Sakata ,  Hideaki Matsumoto

发明人： Takashi Sakata ,  Hideaki Matsumoto

IPC分类号： G01N1/30 ,  G01N33/52 ,  G01N33/48

CPC分类号： G01N33/52 ,  G01N1/30 ,  Y10S436/811 ,  Y10T436/108331

摘要： A reagent for staining malaria infected cells and a method for detecting malaria infected cells using the same, wherein the regent is a staining solution comprising at least one first dye of an Auramine analogue having the formula (I): ##STR1## wherein R.sub.1 to R.sub.6 represents a hydrogen atom, or a methyl or ethyl group, X.sub.1 represents a halogen atom, and at least one second dye of a condensed benzene derivative having the formula (II): ##STR2## wherein A represents ##STR3## R represents a C.sub.1-6 alkyl group, X.sub.2 represents a halogen atom, Y represents --CH.dbd. or --NH--, n represents 0 or 1, and B represents ##STR4## or a phenyl group substituted with 2 lower alkoxy group or with 1 di-lower alkylamino group. A test sample is treated with reagent to stain malaria infected cells. The stained malaria infected cells are then optically detected.

摘要翻译： 用于染色疟疾感染细胞的试剂和使用该试剂检测疟疾感染细胞的方法，其中所述摄取剂是包含至少一种具有式（I）的Auramine类似物的至少一种第一染料的染色溶液：其中 R1至R6表示氢原子，或甲基或乙基，X1表示卤素原子，和至少一种具有式（II）的稠合苯衍生物的第二种染料：其中A表示 R表示C 1-6烷基，X 2表示卤素原子，Y表示-CH =或-NH-，n表示0或1，B表示“或”被2个低级烷氧基取代的苯基或与 1二低级烷基氨基。 用试剂处理测试样品染色疟疾感染的细胞。 然后光学检测染色的疟疾感染的细胞。

公开(公告)号：US5296378A

公开(公告)日：1994-03-22

申请号：US947784

申请日：1992-09-18

申请人： Takashi Sakata ,  Tomoyuki Kuroda

发明人： Takashi Sakata ,  Tomoyuki Kuroda

IPC分类号： G01N15/14 ,  G01N33/50 ,  G01N33/49

CPC分类号： G01N33/5094 ,  G01N15/1456 ,  Y10S436/80 ,  Y10T436/107497

摘要： A method for classifying leukocytes with a flow cytometer by use of optical measurements on fluorochrome-stained blood cells. The method comprises the steps of lysing erythrocytes in a blood sample, selectively staining eosinophils and basophils, permitting stained sample to flow through a flow cytometer, and identifying and counting the type of each leukocyte.

摘要翻译： 使用荧光染料染色的血细胞上的光学测量法，用流式细胞仪分类白细胞的方法。 该方法包括以下步骤：在血液样品中裂解红细胞，选择性染色嗜酸性粒细胞和嗜碱性粒细胞，允许染色的样品流过流式细胞仪，以及鉴定和计数每种白细胞的类型。

公开(公告)号：US5250437A

公开(公告)日：1993-10-05

申请号：US596207

申请日：1990-10-10

申请人： Syouzou Toda ,  Takashi Sakata ,  Yukio Hamaguchi

发明人： Syouzou Toda ,  Takashi Sakata ,  Yukio Hamaguchi

IPC分类号： G01N33/49 ,  G01N33/50 ,  G01N33/72 ,  G01N33/48

CPC分类号： G01N33/721 ,  G01N33/5094 ,  Y10T436/10 ,  Y10T436/101666 ,  Y10T436/107497 ,  Y10T436/108331

摘要： A reagent for measuring the hemoglobin concentration and counting the number of leukocytes in a blood sample, which contains at least one of a quaternary ammonium salt or a pyridinium salt, having a concentration capable of hemolyzing erythrocytes in the blood and denaturing hemoglobin and at least one of cationic, nonionic or amphoteric surfactants or an oxidant capable of oxidizing heme in hemoglobin, the reagent being capable of dividing leukocytes into two or three fractions, for example, a fraction of lymphocytes, a fraction of monocytes, eosinophils and basophils, and a fraction of neutrophils.

公开(公告)号：US5087971A

公开(公告)日：1992-02-11

申请号：US603044

申请日：1990-10-25

申请人： Takashi Sakata ,  Toshiharu Yumoto

发明人： Takashi Sakata ,  Toshiharu Yumoto

IPC分类号： A61B6/03 ,  G06T3/40 ,  H04N1/387

CPC分类号： H04N1/3875

摘要： A video signal processing device is incorporated in an image output device such as a thermal printer which is connected to an analog video signal source such as a computerized medical diagnostic imaging system, e.g., a CT scanner. The video signal processing device has a memory which stores data for determining the total number of horizontal pixels along a single horizontal line in a frame based on the number of frames to be displayed on a display unit or recorded on a recording medium, and the aspect ratio of the frames, and data for determining the frequency of the sampling pulses supplied to an A/D converter based on the total number of horizontal pixels and the number of scanning lines of the analog video signal. Based on the data stored in the memory, a processor supplies sampling pulses to the A/D converter depending on input and output conditions which are entered through a control panel by the operator. The video output device can easily display or record desired image information in a single frame or a plurality of frames on a display unit or a recording medium.

摘要翻译： 视频信号处理装置并入图像输出装置，例如热敏打印机，其连接到模拟视频信号源，例如计算机医疗诊断成像系统，例如CT扫描器。 视频信号处理装置具有存储器，用于存储用于基于要在显示单元上显示或记录在记录介质上的帧数来确定沿着单个水平线的水平像素的总数的数据，并且该方面 根据水平像素的总数和模拟视频信号的扫描线数，确定提供给A / D转换器的采样脉冲的频率的数据。 基于存储在存储器中的数据，处理器根据由操作者通过控制面板输入的输入和输出条件向A / D转换器提供采样脉冲。 视频输出设备可以容易地在显示单元或记录介质上的单个帧或多个帧中显示或记录期望的图像信息。

公开(公告)号：US07965727B2

公开(公告)日：2011-06-21

申请号：US11878915

申请日：2007-07-27

申请人： Takashi Sakata ,  Noboru Iwabuchi ,  Takashi Kawakami

发明人： Takashi Sakata ,  Noboru Iwabuchi ,  Takashi Kawakami

IPC分类号： H04L12/56

CPC分类号： H04L47/10 ,  H04H20/40 ,  H04H20/82 ,  H04L45/00 ,  H04L45/22 ,  H04L45/50 ,  H04L47/30

摘要： An IP encapsulator in a broadcast distributing system divides broadcast data received from an image distributing source into packets, and IP-encapsulates the packets. The IP encapsulator transmits the IP-encapsulated packets to a subscriber line terminal (SLT) via a network. The SLT includes a memory that stores therein broadcast data, and performs TOS control and transfer-route switching control based on memory occupancy of the SLT.

摘要翻译： 广播分发系统中的IP封装器将从图像分发源接收的广播数据分成分组，并且IP封装分组。 IP封装器通过网络将IP封装的数据包发送到用户线路终端（SLT）。 SLT包括存储广播数据的存储器，并且基于SLT的存储器占用执行TOS控制和传送路由切换控制。

公开(公告)号：US20050123299A1

公开(公告)日：2005-06-09

申请号：US11043039

申请日：2005-01-27

申请人： Takashi Sakata ,  Kenichi Sasaki

发明人： Takashi Sakata ,  Kenichi Sasaki

IPC分类号： H04J14/02

CPC分类号： H04J14/02

摘要： A wavelength division multiplexing optical transmission system for multiplexing a plurality of optical signals of the wavelength different from each other. The system comprises a first converter converting the plurality of optical signals whose wavelengths are different from each other, into a plurality of electric signals, a generator generating check symbols for the plurality of electric signals input from the first converter, a second converter converting the check symbols input from the generator, into optical signals whose wavelengths are different from the plurality of optical signals, a multiplexer multiplexing and sending out the plurality of optical signals and the optical signals input from the second converter, and an isolator isolating the multiplexed optical signal input from the multiplexer.

摘要翻译： 一种波分复用光传输系统，用于复用彼此不同的波长的多个光信号。 该系统包括将波长彼此不同的多个光信号转换为多个电信号的第一转换器，产生从第一转换器输入的多个电信号的检查符号的发生器，转换检查的第二转换器 从发生器输入的符号转换为波长不同于多个光信号的光信号，复用多路复用并发出多个光信号和从第二转换器输入的光信号，以及隔离器将多路复用的光信号输入 从多路复用器。

公开(公告)号：US06288806B1

公开(公告)日：2001-09-11

申请号：US09046528

申请日：1998-03-24

申请人： Eisaku Touma ,  Takashi Sakata

发明人： Eisaku Touma ,  Takashi Sakata

IPC分类号： H04J1402

CPC分类号： H04Q11/0062 ,  H04B10/038 ,  H04B10/07 ,  H04B10/0793 ,  H04L41/06 ,  H04L41/0677 ,  H04Q11/0067 ,  H04Q2011/0081 ,  H04Q2011/0083

摘要： The invention provides an optical subscriber network system which can secure dual construction of optical transmission/reception sections of optical network units, specification of a failed faulty point in optical transmission lines and reception circuits of the optical network units and regular timing transmission of upstream data. The optical subscriber network system has a passive optical network construction wherein a plurality of network units are accommodated in a station apparatus through an optical transmission line using a passive optical element, and includes bypass transmission lines for mutual supervision control between the network units. A network unit mutual supervision control signal is communicated between the network units through the bypass transmission lines. The network unit mutual supervision control information received by each of the network units is transmitted to the station apparatus through the optical transmission line so that a fault is supervised based on the network unit mutual supervision control information by the station apparatus.

摘要翻译： 本发明提供了一种可以保证光网络单元的光发送/接收部分的双重构造，光传输线路中的故障故障点的定义和光网络单元的接收电路的定制传输的光用户网络系统。 光用户网络系统具有无源光网络结构，其中多个网络单元通过使用无源光学元件的光传输线路容纳在站设备中，并且包括用于网络单元之间的相互监督控制的旁路传输线。 网络单元相互监督控制信号通过旁路传输线在网络单元之间进行通信。 由网络单元接收的网络单元相互监视控制信息通过光传输线路发送到站设备，从而基于站设备的网络单元相互监督控制信息来监视故障。

公开(公告)号：US5618733A

公开(公告)日：1997-04-08

申请号：US360005

申请日：1994-12-20

申请人： Takashi Sakata ,  Takashi Morikawa ,  Kinya Uchihashi ,  Tomomi Hashimoto

发明人： Takashi Sakata ,  Takashi Morikawa ,  Kinya Uchihashi ,  Tomomi Hashimoto

IPC分类号： G01N33/48 ,  G01N15/14 ,  G01N33/49 ,  G01N33/50 ,  G01N33/52

CPC分类号： G01N33/5002 ,  G01N15/1459 ,  G01N2015/1006 ,  G01N2015/1402 ,  G01N2015/1477 ,  G01N2015/1488 ,  G01N2021/4716 ,  Y10T436/107497

摘要： A reagent for analyzing leucocytes comprises (a) at least one ionic surfactant, being either a cationic or an amphoteric surfactant, in an amount sufficient for lysing erythrocytes and causing damage to a part of cell membranes of leucocytes; (b) at least one organic compound having a hydrophobic group and an acidic group which has a negative charge in an aqueous solution in an amount sufficient for a preserving leucocyte morphology by combining with a cationic component in leucocytes; (c) a nonionic surfactant; and (d) a buffer for adjusting pH.

摘要翻译： 用于分析白细胞的试剂包含（a）至少一种离子表面活性剂，阳离子表面活性剂或两性表面活性剂，其量足以溶解红细胞并对白细胞的一部分细胞膜造成损伤; （b）通过与白细胞中的阳离子组分结合，至少一种具有疏水基团和酸性基团的具有负电荷的有机化合物，其量足以保持白细胞形态; （c）非离子表面活性剂; 和（d）用于调节pH的缓冲液。

公开(公告)号：US5538893A

公开(公告)日：1996-07-23

申请号：US426003

申请日：1995-04-20

申请人： Takashi Sakata ,  Yasumasa Akai ,  Kaoru Takarada ,  Chihiro Kouzuki ,  Yoshihiro Hyousa

发明人： Takashi Sakata ,  Yasumasa Akai ,  Kaoru Takarada ,  Chihiro Kouzuki ,  Yoshihiro Hyousa

IPC分类号： G01N33/48 ,  G01N33/49 ,  G01N33/50 ,  G01N31/00

CPC分类号： G01N33/5094 ,  G01N15/1434 ,  G01N15/1459 ,  G01N2015/1006 ,  G01N2015/1402 ,  Y10T436/10 ,  Y10T436/101666 ,  Y10T436/107497 ,  Y10T436/25125

摘要： A reagent for analyzing leukocytes having at least one nonionic surfactant having an addition polymerization molar number of polyoxyethylene of 3 to 9, at least one cationic surfactant, and a buffer adjusting a pH value to 2.5 to 4.0, which can determine a cell size of and the morphological features of leukocytes contained in the blood sample.

摘要翻译： 一种用于分析白细胞的试剂，其具有至少一种聚合摩尔数为3至9的非离子表面活性剂，至少一种阳离子表面活性剂和调节pH值至2.5至4.0的缓冲剂，其可以确定细胞的大小和 血液样本中含有的白细胞的形态学特征。

公开(公告)号：US5264369A

公开(公告)日：1993-11-23

申请号：US902979

申请日：1992-06-23

申请人： Takashi Sakata ,  Mitsue Ito

发明人： Takashi Sakata ,  Mitsue Ito

IPC分类号： G01N1/28 ,  G01N15/00 ,  G01N15/14 ,  G01N33/49 ,  G01N33/50 ,  G01N33/48

CPC分类号： G01N33/5094 ,  G01N15/147 ,  G01N2015/0069 ,  G01N2015/008 ,  G01N2015/1037 ,  G01N2015/1486 ,  G01N2021/6441 ,  Y10S436/80 ,  Y10T436/107497

摘要： A hematological specimen for classifying and counting leukocytes with a flow cytometer is prepared. A sample to be assayed is prepared by eliminating influences of erythrocytes from a hematological sample without changing leukocytes morphologically by adding a first aqueous solution of a low osmotic pressure including a buffer for adjusting the pH value within an acidic region and a second aqueous solution including an osmolarity compensating agent and a buffer for giving pH value suitable for staining, optionally further adding a salt, which dissociates into ions in aqueous solutions so as to control the electrical conductivity of the aqueous solution at a preferable level, while damaging the cell membranes of erythroblasts contained in said sample; and staining the leukocytes with at least four dyes including Astrazon Yellow 3G and Neutral Red. Thus leukocytes contained in the hematological sample can be classified into at least eight groups including immature granulocytes, erythroblasts, basophils, eosinophils, lymphocytes, monocytes and neutrophils, or nine groups invoving one having blasts in addition to the above-mentioned eight groups, by assaying a single specimen with a flow cytometer.