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    PHOTORESPONSIVE, FORM-STABLE PHASE CHANGE COMPOSITES AND PHOTODETECTORS MADE THEREFROM
    22.
    发明申请
    PHOTORESPONSIVE, FORM-STABLE PHASE CHANGE COMPOSITES AND PHOTODETECTORS MADE THEREFROM 有权
    光电子，形态稳定相变复合材料和光电转换器

    公开(公告)号：US20160319175A1

    公开(公告)日：2016-11-03

    申请号：US15093857

    申请日：2016-04-08

    申请人： Wisconsin Alumni Research Foundation

    发明人： Shaoqin Gong ,  Zhenqiang Ma ,  Yunming Wang ,  Hongyi Mi

    IPC分类号： C09K5/14 ,  H01L45/00 ,  H01L51/44

    CPC分类号： C09K5/14 ,  H01L27/305 ,  H01L51/0049 ,  H01L51/42 ,  H01L51/44 ,  Y02E10/549 ,  Y02P70/521

    摘要： Composite materials comprising electrically conductive particles in a form-stable phase change materials (PCMs) are provided. Also provided as radiation sensors incorporating the composites and methods for detecting radiation using the composites. The PCMs comprise crosslinked polyether polyol that undergoes a reversible solid-solid phase change upon heating. Prior to the phase change, the crosslinked polyether polyol comprises microscopic crystalline domains. When the PCM is heated beyond its phase transition temperature these microscopic crystalline domains melt. However, the form-stable PCMs retain their solid form at the macroscopic level.

    摘要翻译： 提供了包含形态稳定相变材料（PCM）中的导电颗粒的复合材料。 还提供了包含复合材料的辐射传感器和用于使用复合材料检测辐射的方法。 PCM包括交联的聚醚多元醇，其在加热时经历可逆的固 - 固相变。 在相变之前，交联的聚醚多元醇包括微观结晶域。 当PCM被加热超过其相变温度时，这些微晶结晶域熔化。 然而，形式稳定的PCM在宏观层面保持其固体形式。

    Flexible transistors with near-junction heat dissipation
    23.
    发明授权
    Flexible transistors with near-junction heat dissipation 有权

    公开(公告)号：US11495512B2

    公开(公告)日：2022-11-08

    申请号：US16862825

    申请日：2020-04-30

    申请人： Wisconsin Alumni Research Foundation

    发明人： Zhenqiang Ma ,  Huilong Zhang ,  Shaoqin Gong

    IPC分类号： H01L23/367 ,  H01L29/66 ,  H01L29/778 ,  H01L23/522

    摘要： Flexible transistors and electronic circuits incorporating the transistors are provided. The flexible transistors promote heat dissipation from the active regions of the transistors while preserving their mechanical flexibility and high-frequency performance. The transistor designs utilize thru-substrate vias (TSVs) beneath the active regions of thin-film type transistors on thin flexible substrates. To promote rapid heat dissipation, the TSVs are coated with a material having a high thermal conductivity that transfers heat from the active region of the transistor to a large-area ground.

    Polyplex delivery system for proteins, nucleic acids and protein/nucleic acid complexes
    25.
    发明授权
    Polyplex delivery system for proteins, nucleic acids and protein/nucleic acid complexes 有权

    公开(公告)号：US11351263B2

    公开(公告)日：2022-06-07

    申请号：US16282174

    申请日：2019-02-21

    申请人： Wisconsin Alumni Research Foundation

    发明人： Shaoqin Gong ,  Yuyuan Wang ,  Krishanu Saha ,  Amr Ashraf Abdeen

    IPC分类号： A61K9/00 ,  A61K47/59 ,  A61K47/61 ,  A61K31/7105 ,  A61K51/06 ,  A61K38/46 ,  A61K49/00

    摘要： Provided herein are nanoplexes comprising a payload selected from a protein and/or a polynucleic acid; and a plurality of copolymers comprising a first copolymer that is poly(N,N′-bis(acryloyl)cystamine-poly(aminoalkyl)) (PBAP), a second copolymer that is poly(C2-3 akylene glycol)-PBAP-poly(C2-3 akylene glycol), and a third copolymer that is TG-poly(C2-3 akylene glycol)-PBAP-poly(C2-3 akylene glycol)-TG wherein TG at each occurrence is independently a targeting ligand, a cell penetrating peptide, an imaging agent or a capping group, provided that a plurality of TG groups is a targeting ligand; wherein the payload is non-covalently complexed to one or more of the copolymers, one or more of the first, second, and/or third copolymers comprises an endosomal escape group having a pKa of about 4.5 to about 6.5, and optionally one or more of the first, second, and/or third copolymers comprises a host and a guest non-covalent crosslinker.

    BIOMIMETIC VESICLES AND USES THEREOF
    26.
    发明申请
    BIOMIMETIC VESICLES AND USES THEREOF 有权

    公开(公告)号：US20210205473A1

    公开(公告)日：2021-07-08

    申请号：US17057415

    申请日：2019-05-23

    申请人： Ohio State Innovation Foundation ,  Wisconsin Alumni Research Foundation

    发明人： K. Craig Kent ,  Shaoqin Gong ,  Lianwang Guo ,  Bowen Wang ,  Guojun Chen ,  Go Urabe

    IPC分类号： A61K47/69 ,  A61K45/06 ,  A61K9/51

    摘要： The present disclosure relates to unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. The disclosed compositions are useful for treating a subject with a disease or condition, such as a cardiovascular disease. In a further aspect, the cardiovascular disease can be a vascular stenosis or restenosis. Also described herein are methods of making and using the unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.