公开(公告)号：US20160071690A1

公开(公告)日：2016-03-10

申请号：US14888414

申请日：2014-05-14

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION

Inventor： Tsumoru SHINTAKE

IPC: H01J37/244 ,  H01J37/295

CPC classification number: H01J37/244 ,  G01N23/20 ,  H01J37/2955 ,  H01J2237/2449 ,  H01J2237/24578 ,  H01J2237/2544 ,  H01J2237/2803

Abstract: A low energy electron diffraction (LEED) detection module (100) includes: a first vacuum chamber for receiving diffracted electrons from a specimen (109); a larger second vacuum chamber connected to the first vacuum chamber to receive the diffracted electrons that have been transported through the first vacuum chamber; a two-dimensional electron detector disposed in the second vacuum chamber to detect the diffracted electrons; a potential shield (106) disposed generally along an inner surface of the first vacuum chamber and an inner surface of the second vacuum chamber; a magnetic lens (105) to expand a beam of the diffracted electrons that have been transported through the first vacuum chamber towards the two-dimensional electron detector; and a generally plane-shaped energy filter (103) to repel electrons having an energy lower than the probe beam (203) of electrons that impinges on the specimen (109).

Abstract translation: 低能电子衍射（LEED）检测模块（100）包括：用于从样品（109）接收衍射电子的第一真空室; 连接到第一真空室的较大的第二真空室，以接收已经传送通过第一真空室的衍射电子; 设置在第二真空室中以检测衍射电子的二维电子检测器; 大致沿第一真空室的内表面设置的电位屏蔽件（106）和第二真空室的内表面; 用于将已经通过第一真空室传送的衍射电子束朝向二维电子检测器扩大的磁性透镜（105）; 和大致平面状的能量过滤器（103），以排斥能量低于碰撞在样本（109）上的电子的探针光束（203）的能量的电子。

公开(公告)号：US20150278451A1

公开(公告)日：2015-10-01

申请号：US14433721

申请日：2013-11-07

Applicant: Okinawa Institute of Science and Technology Graduate University ,  SBX Corporation ,  The Systems Biology Institute

Inventor： Hiroaki Kitano ,  Samik Ghosh ,  Yukiko Matsuoka

IPC: G06F19/00 ,  G06F17/30 ,  G06F21/62

CPC classification number: G06F19/322 ,  G06F17/30876 ,  G06F19/00 ,  G06F21/6218 ,  G06F21/6245 ,  G06F2221/2113 ,  G16H10/60

Abstract: In a plurality of data analysis apparatuses communicatively coupled to one another, a database is accessed at a given access level. Based on the data acquired from the database, an application program is executed to perform data analysis. Communication control is performed to allow transmission and reception of a data analysis result with respect to another data analysis apparatus at a different access level.

Abstract translation: 在通信地彼此耦合的多个数据分析装置中，在给定的访问级别访问数据库。 基于从数据库获得的数据，执行应用程序以执行数据分析。 执行通信控制以允许相对于不同访问级别的另一数据分析装置发送和接收数据分析结果。

公开(公告)号：US20150024491A1

公开(公告)日：2015-01-22

申请号：US14388340

申请日：2012-03-27

Applicant: Dimitar Ivanov Dimitrov ,  Laurent Elie Guillaud ,  Zacharie Mehdi Francois Taoufiq ,  Tomoyuki Takahashi

Inventor： Dimitar Ivanov Dimitrov ,  Laurent Elie Guillaud ,  Zacharie Mehdi Francois Taoufiq ,  Tomoyuki Takahashi

IPC: C12N5/0793 ,  C12N5/079

CPC classification number: C12N5/0619 ,  C12N5/0618 ,  C12N2500/05 ,  C12N2501/115 ,  C12N2501/13 ,  C12N2502/086

Abstract: An object of the present invention is to develop and provide a method for producing a neuron model having reproduced in vivo properties by improving a cell culture medium composition and a cell culture medium composition necessary for the production of such neuron model. According to the present invention, cell culture is carried out in vitro using a medium for producing in vivo-like and enhanced synaptogenesis neuron model supplemented with a medium supplement for producing in vivo-like and enhanced synaptogenesis neuron model comprising any or any combination of NT-3, potassium or a salt thereof, and FGF2.

Abstract translation: 本发明的目的是开发和提供一种通过改善细胞培养基组合物和产生这种神经元模型所必需的细胞培养基组合来产生具有再生体内特性的神经元模型的方法。 根据本发明，使用培养基进行细胞培养，所述培养基用于产生体内和增强的突触形成神经元模型，其补充有用于产生体内样和增强的突触形成神经元模型的培养基补充，所述模型包括NT的任何或任何组合 -3，钾或其盐和FGF2。

公开(公告)号：US08035086B2

公开(公告)日：2011-10-11

申请号：US12379442

申请日：2009-02-23

Applicant: Yoichi Hirayama ,  Takaho Yoshida

Inventor： Yoichi Hirayama ,  Takaho Yoshida

IPC: H01J3/24

CPC classification number: H01J3/12 ,  H01J37/153 ,  H01J37/26 ,  H01J2237/1534 ,  H01J2237/28

Abstract: To provide an aberration correction configuration that can realize both an aberration correction function for a long focus and an aberration correction function for a short focus. While having a conventional aberration correction apparatus configuration that has two rotationally symmetric lenses arranged between two multipole lenses, three rotationally symmetric lenses are disposed between an objective lens and a multipole lens instead of the conventional arrangement in which two rotationally symmetric lenses are disposed therebetween. When using the objective lens with a long focal length, aberrations are corrected using two rotationally symmetric lenses among three rotationally symmetric lenses disposed between the objective lens and the multipole lens. When using the objective lens with a short focal length, e.g. for high resolution observation, aberrations are corrected using two rotationally symmetric lenses of a different combination to those used for a long focus, among the three rotationally symmetric lenses disposed between the objective lens and the multipole lens. (See FIG. 3)

Abstract translation: 提供能够实现长焦点的像差校正功能和短焦点的像差校正功能的像差校正配置。 在具有布置在两个多极透镜之间的两个旋转对称透镜的常规像差校正装置配置的同时，三个旋转对称透镜设置在物镜和多极透镜之间，而不是其中设置两个旋转对称透镜的常规布置。 当使用具有长焦距的物镜时，使用设置在物镜和多极镜头之间的三个旋转对称透镜之中的两个旋转对称透镜校正像差。 当使用具有短焦距的物镜时，例如， 对于高分辨率观察，在物镜和多极透镜之间设置的三个旋转对称透镜中，使用与用于长焦距的不同组合的两个旋转对称透镜来校正像差。 （参照图3）

公开(公告)号：US20240352310A1

公开(公告)日：2024-10-24

申请号：US18688184

申请日：2022-08-29

Applicant: Okinawa Institute of Science and Technology School Corporation

Inventor： Ayumu KARIMATA ,  Julia KHUSNUTDINOVA

IPC: C09K11/06 ,  C09K11/02

CPC classification number: C09K11/06 ,  C09K11/02 ,  C09K2211/1011

Abstract: Triboluminescent materials that produce light emission in response to mechanical action attract significant interest due to their wide range of potential utilization for mechanoresponsive sensors, light emitting devices and stimuli-induced glowing fibers, dyes, particles, paste, and films, etc. Here, we would like to disclose a general method of generating triboluminescent polymer materials blended with wide range of luminophores that emit light in response to mechanical action emitting light in a wide range of spectrum. The light generation is achieved via a non-destructive method even in the absence of direct contact with the polymer (e.g. through the layer of another polymer). Biocompatible luminophores can be easily utilized. Light emission is also observed under dry air.

公开(公告)号：US12116383B2

公开(公告)日：2024-10-15

申请号：US17841241

申请日：2022-06-15

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION

Inventor： Fujie Tanaka ,  Sherida Johnson

IPC: C07H7/04 ,  C07H1/00

CPC classification number: C07H7/04 ,  C07H1/00

Abstract: The present invention provides a novel process for preparing an oligosaccharide C-glycoside derivative of formula I, comprising reacting a compound of formula II with compound of formula III in the presence of at least one primary or secondary amine and at least one additive [in the formulae, the substituents are as defined herein], and novel oligosaccharide C-glycoside derivatives that can be prepared using the process.

公开(公告)号：US11867597B2

公开(公告)日：2024-01-09

申请号：US17677298

申请日：2022-02-22

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION

Inventor： Nikhil Bhalla ,  Amy Shen Fried ,  Kang-Yu Chu

IPC: G01N21/75 ,  G01N33/543 ,  C03C17/09 ,  G01N21/552 ,  G01N21/41

CPC classification number: G01N33/54373 ,  C03C17/09 ,  G01N21/554 ,  C03C2217/255 ,  C03C2218/151 ,  C03C2218/33 ,  G01N21/41

Abstract: A method for making a plasmonic mushroom array includes: forming a plurality of metal nano-islands each having nanometer-range dimensions on a surface of a glass substrate; and subjecting to the glass substrate having the plurality of metal nano-islands formed thereon to reactive ion etching such that the plurality of metal nano-islands are converted to a plurality of mushroom-shaped structures each having a metal cap supported by a pillar made of a material of the glass substrate and each having dimensions smaller than the dimensions of the nano-islands, the plurality of mushroom-shaped structures being arranged in a substantially regular pattern with intervals smaller than average intervals between the nano-islands, thereby forming the plurality of nano-scale mushroom-shaped structures on the glass substrate that can exhibit localized surface plasmon resonance.

公开(公告)号：US20230231118A1

公开(公告)日：2023-07-20

申请号：US18011357

申请日：2021-09-07

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION

Inventor： Panagiotis GRAMMATIKOPOULOS ,  Marta HARO ,  Junlei ZHAO ,  Emilio Jose JUAREZ-PEREZ

IPC: H01M4/38 ,  H01M4/134 ,  H01M4/04 ,  H01M4/1395

CPC classification number: H01M4/386 ,  H01M4/134 ,  H01M4/0471 ,  H01M4/1395 ,  H01M4/0423 ,  H01M2004/027

Abstract: A composite nanoarchitecture unit is disclosed. The unit comprises a columnar film grown on top of another layer where the columns touch each other at the top forming arches having optimized characteristics. This nanoarchitecture unit, called nano-vault, achieves high mechanical stability for films under strong and variable stress action.

公开(公告)号：US11677206B2

公开(公告)日：2023-06-13

申请号：US16806874

申请日：2020-03-02

Applicant: Okinawa Institute of Science and Technology School Corporation

Inventor： Yuimaru Kubo ,  Jason Robert Ball ,  Petr Moroshkin ,  Denis Konstantinov

IPC: H01S1/02

CPC classification number: H01S1/02

Abstract: Embodiments of the microwave amplification system are described. In an embodiment, a microwave amplification system includes a microwave amplifier that contains a paramagnetic material with an impurity. The impurity has a plurality of nuclear spin and electron spin-based energy levels. The system includes an input to receive a pumping signal which is transmitted to the microwave amplifier to cause a population inversion in the impurity and excite it to one of the nuclear spin and electron spin-based energy levels. The system further includes another input to receive an input signal to be amplified by the microwave amplifier, the input signal having a lower power than the pumping signal. Once transmitted to the microwave amplifier, the input signal is amplified by the excited state of the impurity in the microwave amplifier thereby generating an amplified signal.

公开(公告)号：US11645574B2

公开(公告)日：2023-05-09

申请号：US16130482

申请日：2018-09-13

Applicant: FUJITSU LIMITED ,  Okinawa Institute of Science and Technology School Corporation

Inventor： Tomotake Sasaki ,  Eiji Uchibe ,  Kenji Doya ,  Hirokazu Anai ,  Hitoshi Yanami ,  Hidenao Iwane

IPC: G06N3/00 ,  G06N20/00 ,  H04L41/0816 ,  G06N3/006 ,  H04L41/16 ,  H04L43/08

CPC classification number: G06N20/00 ,  G06N3/006 ,  H04L41/0816 ,  H04L41/16 ,  H04L43/08

Abstract: A non-transitory, computer-readable recording medium stores therein a reinforcement learning program that uses a value function and causes a computer to execute a process comprising: estimating first coefficients of the value function represented in a quadratic form of inputs at times in the past than a present time and outputs at the present time and the times in the past, the first coefficients being estimated based on inputs at the times in the past, the outputs at the present time and the times in the past, and costs or rewards that corresponds to the inputs at the times in the past; and determining second coefficients that defines a control law, based on the value function that uses the estimated first coefficients and determining input values at times after estimation of the first coefficients.