Abstract:
Methods for evaluating micrometastases in a tissue region of a subject are described. The methods include administering to the subject a detectably effective amount of a tumor-targeted photoactivatable immunoconjugate; allowing a sufficient amount of time for the tumor-targeted photoactivatable immunoconjugate to enter micrometastases in the tissue region; illuminating the tumor-targeted photoactivatable immunoconjugate; obtaining an image of the tissue region of the subject using a fluorescent imaging device, and evaluating the micrometastases in the tissue region by conducting algorithmic analysis of the image. Methods of treating micrometastases in a tissue region of a subject are also described.
Abstract:
A validatable method for determining a photochemically effective dose for inactivating pathogens in a fluid sample is described herein. In particular, the instant invention covers methods for determining a photochemically effective dose sufficient to inactivate pathogens in a biological sample while leaving biologically active substances of interest unaffected. A batch irradiation reactor effective for inactivating pathogens in biological samples is also described.
Abstract:
A air gas detection pack is provided. The air gas detection pack has a card receiving pocket which slidably receives a gas detection card, the gas detection card having a plurality of chemically reactive materials retained therein and exposed to outside air through a plurality of aligned air permeable apertures formed in the front and rear wall of the substance detection pack. The combined gas detection card and gas detection pack indicates the concentrations of gases in the air. The air permeable apertures in conjunction with the reactive materials of the substance detection card are covered with a filtering media to protect the reactive material from dirt and dust contamination.
Abstract:
A validatable method for determining a photochemically effective dose for inactivating pathogens in a fluid sample is described herein. In particular, the instant invention covers methods for determining a photochemically effective dose sufficient to inactivate pathogens in a biological sample while leaving biologically active substances of interest unaffected. A batch irradiation reactor effective for inactivating pathogens in biological samples is also described.
Abstract:
The invention relates to a device for detecting input radiation such as X-rays, &ggr;-rays, ionizing radiation or fluorescent and low-level light. The device has at least one detection element comprising a sensor component (scintillator) for converting the input radiation into photons (scintillation light) in the UV, visible or IR part of the electromagnetic spectrum and an optical amplifier component which receives the light converted by the sensor component, forwards it for further processing and amplifies it at the same time. According to the invention, the amplifier component comprises at least one optical waveguide (1, 2, 2a, 2b, 20) whose material is optically pumped to amplify the scintillation light (3, 24, 25).
Abstract:
Radiation-dose indicator as well as a lamp and a tanning apparatus comprising such a radiation-dose indicator. The invention provides a novel type of radiation-dose indicator which is reliable and accurate. The indicator comprises an optically active layer which includes a liquid-crystalline material as well as a radiation-sensitive compound. This compound is converted under the influence of radiation in such a way as to change the order of the liquid-crystalline material. Preferably, a trans-isomer is used as the radiation-sensitive compound, which is converted to the corresponding cis-isomer under the influence of radiation. In this way, the order of the liquid-crystalline material is broken. Indicators in accordance with the invention can very advantageously be used in UV- and IR-lamps as well as in tanning apparatus.
Abstract:
An ultraviolet light sensitive emulsion material, which becomes transparent to the user only after the ultraviolet light sensitive emulsion material is exposed to a predetermined amount of ultraviolet light, to expose a colored backing surface to view. In one form of the invention, an ultraviolet light inhibiting material is disposed in covering or blocking relationship relative to the emulsion material arranged in a graduated pattern of varying opacity, for inhibiting passage of ultraviolet light selectively to the ultraviolet light sensitive emulsion material to enable the emulsion to be rendered transparent in a series of graduated indications when the device is exposed to progressively longer periods of time.
Abstract:
A solar energy flux integrator includes a semiconducting solar cell positioned to receive solar radiation, and a micro-coulombmeter connected to receive current from the solar cell. The micro-coulombmeter comprises a glass capillary filled with a mercury salt electrolyte having an indicating bubble and two mercury electrodes. A series resistor is provided which has a resistance value to slow the movement of the bubble when low levels of solar energy are incident on the cell so that movement of the bubble is directly proportional to the incident solar flux. This series resistor compensates for the spectral shift towards blue of the indirectly received solar radiation, which spectral shift otherwise causes the measured integrated value of solar flux to be too high due to the greater sensitivity of the solar cell to light of shorter wavelengths. A parallel resistor is provided to scale the output of the solar cell to the Micro-Coulombmeter and a reversing switch is connected to permit travel of the indicating bubble in opposite directions.
Abstract:
A solution is formed of a polymer which degrades in the presence of light and a photograding compound which degrades the polymer when exposed to light. A non-photo-reducible dye may be included in the solution to filter out unwanted wavelengths. When the solution is exposed to light, the polymer is degraded and the viscosity of the solution is lowered. The solution is conveniently packaged in a sealed tube with a bubble of a noninterfering gas, and the viscosity of the solution is determined by timing the rise of the bubble. The amount of light striking the meter may be determined by comparing the time required for the gas bubble to rise in the tube with the time required for a bubble to rise in identically filled tubes exposed to various known quantities of light.