Antiviral compositions containing bis-basic ketones of thioxanthene
    21.
    发明授权
    Antiviral compositions containing bis-basic ketones of thioxanthene 失效
    含有噻吨酮双碱性酮的抗病毒组合物

    公开(公告)号:US3957988A

    公开(公告)日:1976-05-18

    申请号:US334075

    申请日:1973-02-20

    IPC分类号: C07D335/12 A01N9/00

    CPC分类号: C07D335/12 Y10S514/889

    摘要: The novel bis-basic ketones of thioxanthene have antiviral activity when administered orally and parenterally. These compounds are represented by the following formula: ##SPC1##Wherein A is a straight or branched alkylene chain having from 1 to about 6 carbon atoms; and each Y isA. the group ##EQU1## wherein R.sup.1 and R.sup.2 are individually hydrogen or lower alkyl having from 1 to about 4 carbon atoms; orB. the group ##EQU2## WHEREIN N IS A WHOLE INTEGER OF 4 OR 5, AND R.sup.3 is hydrogen or lower alkyl having from 1 to about 4 carbon atoms and can be linked to any one of the carbon atoms of the heterocyclic group; orC. the group ##EQU3## wherein X is oxygen or NR.sup.4, and R.sup.4 is hydrogen or lower alkyl of from 1 to about 4 carbon atoms; or pharmaceutically acceptable acid addition salts of said base.These new compounds can be prepared by several different methods which are described.

    摘要翻译: 当口服和肠胃外给药时,噻吨酮的新型双碱性酮具有抗病毒活性。 这些化合物由下式表示: