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    CONTINUOUS ANALYTE SENSORS AND METHODS OF MAKING SAME
    294.
    发明申请
    CONTINUOUS ANALYTE SENSORS AND METHODS OF MAKING SAME 审中-公开
    连续分析传感器及其制作方法

    公开(公告)号：US20140343386A1

    公开(公告)日：2014-11-20

    申请号：US14451332

    申请日：2014-08-04

    Applicant: DexCom, Inc.

    Inventor： Robert J. Boock ,  Jeff Jackson ,  Huashi Zhang ,  Jason Mitchell

    IPC: A61B5/1473 ,  A61B5/145

    Abstract: Described here are embodiments of processes and systems for the continuous manufacturing of implantable continuous analyte sensors. In some embodiments, a method is provided for sequentially advancing an elongated conductive body through a plurality of stations, each configured to treat the elongated conductive body. In some of these embodiments, one or more of the stations is configured to coat the elongated conductive body using a meniscus coating process, whereby a solution formed of a polymer and a solvent is prepared, the solution is continuously circulated to provide a meniscus on a top portion of a vessel holding the solution, and the elongated conductive body is advanced through the meniscus. The method may also comprise the step of removing excess coating material from the elongated conductive body by advancing the elongated conductive body through a die orifice.

    Abstract translation: 这里描述了用于连续制造可植入的连续分析物传感器的方法和系统的实施方案。 在一些实施例中，提供了一种用于使细长导电体顺序地前进穿过多个台的方法，每个台被构造成处理细长导电体。 在这些实施例中的一些实施例中，一个或多个工位被配置为使用弯液面涂覆工艺涂覆细长导电体，由此制备由聚合物和溶剂形成的溶液，该溶液被连续循环以在 保持溶液的容器的顶部，并且细长导电体前进通过弯液面。 该方法还可以包括通过使细长导电体通过模头孔从细长导电体去除多余涂层材料的步骤。

    OUTLIER DETECTION FOR ANALYTE SENSORS
    296.
    发明申请
    OUTLIER DETECTION FOR ANALYTE SENSORS 审中-公开
    分析仪传感器的出口检测

    公开(公告)号：US20140188402A1

    公开(公告)日：2014-07-03

    申请号：US13733810

    申请日：2013-01-03

    Applicant: DEXCOM, INC.

    Inventor： Arturo Garcia ,  Naresh C. Bhavaraju ,  Hari Hampapuram ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Dmytro Sokolovskyy ,  Stephen J. Vanslyke

    IPC: G06F19/00

    CPC classification number: G01N33/48792 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7221 ,  A61B2560/0223 ,  A61B2560/0266 ,  A61B2560/0276 ,  A61B2560/028 ,  G01M99/008 ,  G01N33/49 ,  G01N33/66 ,  G16C20/80 ,  G16C99/00

    Abstract: Systems and methods for processing sensor data and end of life detection are provided. In some embodiments, a method for determining the end of life of a continuous analyte sensor includes evaluating a plurality of risk factors using an end of life function to determine an end of life status of the sensor and providing an output related to the end of life status of the sensor. The plurality of risk factors may be selected from the list including the number of days the sensor has been in use, whether there has been a decrease in signal sensitivity, whether there is a predetermined noise pattern, whether there is a predetermined oxygen concentration pattern, and error between reference BG values and EGV sensor values.

    Abstract translation: 提供了用于处理传感器数据和寿命终止检测的系统和方法。 在一些实施例中，用于确定连续分析物传感器的寿命终止的方法包括使用寿命终止功能评估多个危险因素以确定传感器的寿命状态并提供与寿命结束相关的输出 传感器的状态 可以从包括传感器已经使用的天数的列表中选择多个危险因素，信号灵敏度是否下降，是否存在预定的噪声模式，是否存在预定的氧浓度模式， 参考BG值和EGV传感器值之间的误差。

    SIGNAL PROCESSING FOR CONTINUOUS ANALYTE SENSOR
    297.
    发明申请
    SIGNAL PROCESSING FOR CONTINUOUS ANALYTE SENSOR 审中-公开
    连续分析传感器信号处理

    公开(公告)号：US20140180049A1

    公开(公告)日：2014-06-26

    申请号：US14189940

    申请日：2014-02-25

    Applicant: DexCom, Inc.

    Inventor： James H. Brauker ,  Victoria E. Carr-Brendel ,  Paul V. Goode ,  Apurv Ullas Kamath ,  James Patrick Thrower ,  Ben Xavier

    IPC: A61B5/145 ,  A61B5/00

    CPC classification number: A61B5/14532 ,  A61B5/145 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/7257 ,  A61B5/726 ,  A61B5/7264 ,  A61B5/7275 ,  A61B5/742 ,  A61B5/7455 ,  A61B5/746 ,  A61B5/7475 ,  A61M5/1723 ,  G06F19/00 ,  Y02A90/22 ,  Y02A90/26

    Abstract: Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.

    Abstract translation: 用于动态和智能地估计来自连续分析物传感器的分析物数据的系统和方法，包括接收数据流，选择多种算法中的一种，以及采用所选择的算法来估计分析物值。 附加数据处理包括评估所选择的估计算法，基于统计学，临床或生理参数分析估计分析物值的变化，将估计的分析物值与相应的测量分析物值进行比较，以及向用户提供输出。 估计可用于补偿时间滞后，匹配传感器数据与相应的参考数据，警告即将到来的临床风险，替换错误的传感器数据信号，并提供更及时的分析物信息，鼓励主动行为和抢占临床风险。

    DUAL ELECTRODE SYSTEM FOR A CONTINUOUS ANALYTE SENSOR
    300.
    发明申请
    DUAL ELECTRODE SYSTEM FOR A CONTINUOUS ANALYTE SENSOR 审中-公开
    用于连续分析仪传感器的双电极系统

    公开(公告)号：US20140128702A1

    公开(公告)日：2014-05-08

    申请号：US14144536

    申请日：2013-12-30

    Applicant: DexCom, Inc.

    Inventor： Mark Brister ,  James R. Petisce ,  Peter Simpson

    IPC: A61B5/1486 ,  A61B5/145

    CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7203 ,  A61B5/742 ,  A61B2560/0223 ,  B33Y70/00 ,  B33Y80/00

    Abstract: Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure additional analyte or non-analyte related signal. Such measurements may provide a background and/or sensitivity measurement(s) for use in processing sensor data and may be used to trigger events such as digital filtering of data or suspending display of data.

    Abstract translation: 本文公开了用于连续分析物传感器（例如连续葡萄糖传感器）的系统和方法。 一个这样的系统利用第一和第二工作电极来测量附加分析物或非分析物相关信号。 这样的测量可以提供用于处理传感器数据的背景和/或灵敏度测量，并且可以用于触发诸如数据的数字滤波或暂停显示数据的事件。

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