公开(公告)号：US11110373B2

公开(公告)日：2021-09-07

申请号：US16349791

申请日：2018-03-06

Applicant: EMD Millipore Corporation

Inventor： Sebastien Cirou ,  Christine Abouayad El Idrissi

IPC: B01D15/04 ,  B01D15/00 ,  B01D15/08 ,  G01N30/88 ,  C12M1/00 ,  C12M3/00 ,  B01D15/14 ,  B01D15/18 ,  C12M1/12

Abstract: The invention concerns an installation for treating biological liquid by chromatography, extending in a longitudinal direction and comprising a supply valve (20b), a supply pump (30) downstream of the valve, instrument members downstream of the pump among which are at least one distribution valve (81a-c, 82a-c, 83a-c) and at least one device (78a-c, 85a-c, 86a-c) for measuring a physico-chemical parameter of the liquid, at least one chromatography column (99a-c) downstream of the instrument members and of the pipes connecting the valve, the pump, the instrument members and the column, instrument members being associated with the chromatography column and each mounted on at least one dedicated control and actuation platform (80a-c), which extends in a vertical direction relative to the generally longitudinal direction of extension of said installation, and which are disposed substantially above each other on said dedicated control and actuation platform.

公开(公告)号：US11034925B2

公开(公告)日：2021-06-15

申请号：US16713117

申请日：2019-12-13

Applicant: EMD Millipore Corporation

Inventor： Paul J. Hung ,  Philip J. Lee

IPC: C12M3/00 ,  B01L3/00 ,  C12M1/32 ,  C12M3/06 ,  C12M1/00 ,  C12M1/12

Abstract: Microfluidic devices, systems, and methods providing for an invasion assay using microfluidic culture systems.

公开(公告)号：US11014031B2

公开(公告)日：2021-05-25

申请号：US16316890

申请日：2017-10-23

Applicant: EMD Millipore Corporation

Inventor： Akshat Gupta ,  Dana Kinzlmaier ,  Kara Pizzelli ,  Elizabeth Goodrich

IPC: B01D37/02 ,  B01D39/18 ,  D21C9/00 ,  B01D71/10 ,  C12M1/12

Abstract: Treatment methods for reduction of (1→3)-β-D-glucan leachables from cellulose-containing filter materials are described.

公开(公告)号：US10900886B2

公开(公告)日：2021-01-26

申请号：US15958480

申请日：2018-04-20

Applicant: EMD Millipore Corporation

Inventor： Philip Janmin Lee ,  Paul Ju-Sung Hung ,  Narendra Maheshri

IPC: G01N15/14 ,  G01N33/487 ,  B01L3/00 ,  G01N33/543 ,  G01N15/00

Abstract: The method, device, and system relate to particle analysis, and in particular, to a microfluidic device designed for trapping particles for analysis. Particles include beads and cells.

公开(公告)号：USD907244S1

公开(公告)日：2021-01-05

申请号：US29694923

申请日：2019-06-14

Applicant: EMD Millipore Corporation

Designer： Paul Sydlowski

公开(公告)号：US10858623B2

公开(公告)日：2020-12-08

申请号：US14870519

申请日：2015-09-30

Applicant: EMD Millipore Corporation

Inventor： Antoni Peters ,  Philip M. Goddard

IPC: C12M1/12 ,  B01D71/82 ,  B01D71/68 ,  B01D67/00

Abstract: Compositions and methods are provided for removing viral contaminants from a chemically defined cell culture medium. Compositions provided herein are resistant to or exhibit reduced fouling by one or more components in a chemically defined cell culture medium.

公开(公告)号：US10766666B2

公开(公告)日：2020-09-08

申请号：US15848156

申请日：2017-12-20

Applicant: EMD Millipore Corporation

Inventor： Sebastien Cirou ,  Rene Reinbigler ,  Virginie Buisson ,  Jean-Louis Weissenbach

IPC: B65D33/00 ,  A61M1/36 ,  B01D61/18 ,  B01D61/20 ,  F04B43/08

Abstract: The invention concerns a device comprising a base (2) and a door (20), said device having a closed door position in which a circuit (8) of the device comprises a bag comprising two flexible films and connectors of the conveying network, and a press (9) comprising a first shell (16) disposed on a front face (5) of said base (2) and a second shell (17) disposed in said door (20); and a hinge system hinging said door (20) relative to said base (2), and disposed only on one side of said door (20) so as to form lateral clearances between said door (20) and said base (2) over the rest of a perimeter of said door (20).

公开(公告)号：US10751669B2

公开(公告)日：2020-08-25

申请号：US14645631

申请日：2015-03-12

Applicant: EMD Millipore Corporation

Inventor： Gabriel Tkacik ,  Philip Goddard ,  Willem Kools ,  Nitin Satav

IPC: B01D69/12 ,  B01D67/00 ,  B01D71/34 ,  B01D61/14 ,  C07K1/34 ,  B01D71/68

Abstract: The present invention is an integral multilayered composite membrane having at least one ultrafiltration layer made by cocasting or sequentially casting a plurality of polymer solutions onto a support to form a multilayered liquid sheet and immersing the sheet into a liquid coagulation bath to effect phase separation and form a multilayered composite membrane having at least one ultrafiltration layer.

公开(公告)号：US20200262175A1

公开(公告)日：2020-08-20

申请号：US16867288

申请日：2020-05-05

Applicant: EMD Millipore Corporation

Inventor： David DeCoste ,  Joseph Cianciolo ,  Michael Furbush ,  John Saragosa

IPC: B32B5/02 ,  G01M3/32 ,  B65D75/58 ,  B65D65/40 ,  B01L3/00 ,  B32B27/40 ,  B32B27/34 ,  B32B27/32 ,  B32B27/12 ,  B32B27/08

Abstract: A material for biocontainers including a multilayered film, the multilayered film having an interior and exterior side, an abrasion-resistant substrate attached to the interior or the exterior side of the film wherein the substrate comprises a polymeric woven fibrous material or a polymeric non-woven fibrous material, a woven fibrous material or a non-woven fibrous material comprising metal fibers, a woven fibrous material or a non-woven fibrous material comprising glass fibers, or a woven fibrous material or a non-woven fibrous material comprising carbon fibers; a polymer backing to attach the substrate to the film, the polymer backing comprising one of polyolefins, polyurethanes and nylons; an outer protective layer disposed on the outside of the substrate to encapsulate the substrate; and a gas impermeable layer that includes ethylene vinyl alcohol disposed intermediate to the substrate and the outer protective layer.

公开(公告)号：US20200254392A1

公开(公告)日：2020-08-13

申请号：US16862137

申请日：2020-04-29

Applicant: EMD Millipore Corporation

Inventor： Salvatore Giglia ,  David Nhiem

IPC: B01D65/10 ,  G01N15/08

Abstract: A method of integrity testing a porous material is disclosed, providing a porous material suitable for filtration to be tested, said porous material having a first surface and a second surface; wetting said porous material with a wetting liquid; providing a gas stream comprising at least first and second gases humidified with said wetting liquid below the saturation vapor pressure of said wetting liquid and wherein said humidified gas stream has a humidity of 50-99%; introducing said gas stream to said first surface of said porous material; causing said first and second gases to flow through said porous material; measuring the concentration of at least one of said first and second gases in the permeate stream exiting said second surface of said porous material; and comparing the measured concentration to a predetermined concentration.