中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

17 records (took 0.015 seconds)

    Micro-incubation systems for microfluidic cell culture and methods
    3.
    发明授权
    Micro-incubation systems for microfluidic cell culture and methods 有权

    公开(公告)号：US10190085B2

    公开(公告)日：2019-01-29

    申请号：US15163818

    申请日：2016-05-25

    Applicant: EMD Millipore Corporation

    Inventor： Philip J. Lee ,  Terry Gaige ,  Wei Hsuan (Jessie) Ho

    IPC: C12M3/06 ,  C12M1/00 ,  C12Q1/02 ,  C12M1/34 ,  B01L3/00 ,  B01L7/00 ,  C12M1/107 ,  C12M1/02 ,  C12M1/36 ,  G01N33/50 ,  G01N33/574

    Abstract: A micro-incubator manifold for improved microfluidic configurations and systems and methods of manufacture and operation for a manifold and automated microfluidic systems are disclosed. Various embodiments relate to assays, systems, and/or devices for culturing cells or other biologic material in controlled environments and are applicable to related fields generally using microfluidic systems. Particular embodiments involve configurations that can be used with various standard automated handling systems, with active or passive loading and perfusion of medium and to provide high-throughput multi-assay automated systems for culturing, viewing, and analyzing cell growth, invasion, movement, chemotaxis or other properties. More specifically, specific embodiments relate to heat control systems for microfluidic culture plates and other automated systems for culture plates.

    Cell culture array system for automated assays and methods of operation and manufacture
    4.
    发明授权
    Cell culture array system for automated assays and methods of operation and manufacture 有权

    公开(公告)号：US10138453B2

    公开(公告)日：2018-11-27

    申请号：US15163368

    申请日：2016-05-24

    Applicant: EMD Millipore Corporation

    Inventor： Paul J. Hung ,  Philip J. Lee

    IPC: C12M3/06 ,  B01L3/00 ,  C12M1/32 ,  C12M1/00 ,  C12M1/36 ,  G01N35/00

    Abstract: A number of novel improved microfluidic configurations and systems and methods of manufacture and operation. In one embodiment, three wells are used for independent cell culture systems in a cell culture array. In a second aspect, artificial sinusoids with artificial epithelial barriers are provided with just one (optionally shared or multiplexed) fluidic inlet and one (optionally shared or multiplexed) fluidic output, where the medium output also functions as a cellular input. A pneumatic cell loader combined with other components provides a fully automated cell culture system. Magnetic alignment of plate molds provides advantages and ease of molded manufacture.

Patent Agency Ranking