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公开(公告)号：US20200208089A1
公开(公告)日：2020-07-02
申请号：US16713117
申请日：2019-12-13
Applicant: EMD Millipore Corporation
Inventor： Paul J. Hung , Philip J. Lee
Abstract: Microfluidic devices, systems, and methods providing for an invasion assay using microfluidic culture systems.
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公开(公告)号：US10138453B2
公开(公告)日：2018-11-27
申请号：US15163368
申请日：2016-05-24
Applicant: EMD Millipore Corporation
Inventor： Paul J. Hung , Philip J. Lee
Abstract: A number of novel improved microfluidic configurations and systems and methods of manufacture and operation. In one embodiment, three wells are used for independent cell culture systems in a cell culture array. In a second aspect, artificial sinusoids with artificial epithelial barriers are provided with just one (optionally shared or multiplexed) fluidic inlet and one (optionally shared or multiplexed) fluidic output, where the medium output also functions as a cellular input. A pneumatic cell loader combined with other components provides a fully automated cell culture system. Magnetic alignment of plate molds provides advantages and ease of molded manufacture.
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Patent Agency Ranking
公开(公告)号：US20160333298A1
公开(公告)日：2016-11-17
申请号：US15175749
申请日：2016-06-07
Applicant: EMD Millipore Corporation
Inventor： Paul J. Hung , Philip J. Lee
CPC classification number: C12M23/16 , B01L3/502715 , B01L3/50273 , B01L3/502746 , B01L3/502761 , B01L2300/069 , B01L2300/0809 , B01L2300/0829 , B01L2300/0848 , B01L2300/0883 , B01L2300/10 , B01L2400/0406 , B01L2400/0457 , B01L2400/0487 , B01L2400/086 , C12M21/08 , C12M23/24 , C12M23/34 , C12M23/40 , C12M23/58 , C12M29/10 , C12M41/12 , C12M41/36
Abstract: A number of novel improved microfluidic configurations and systems and methods of manufacture and operation.
Abstract translation: 许多新颖的改进的微流体配置以及制造和操作的系统和方法。
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4.发明申请Cell Culture Array System For Automated Assays And Methods Of Operation And Manufacture 审中-公开用于自动测定的细胞培养阵列系统和操作和制造方法公开(公告)号：US20160289623A1
公开(公告)日：2016-10-06
申请号：US15163368
申请日：2016-05-24
Applicant: EMD Millipore Corporation
Inventor： Paul J. Hung , Phillip J. Lee
CPC classification number: C12M23/16 , B01L3/5025 , B01L3/5027 , B01L3/502715 , B01L3/50273 , B01L3/502761 , B01L2300/0829 , B01L2300/0848 , B01L2300/0861 , B01L2400/0457 , B01L2400/0487 , C12M23/12 , C12M29/10 , C12M41/48 , G01N35/00029 , G01N35/0099 , G01N2035/00148
Abstract: A number of novel improved microfluidic configurations and systems and methods of manufacture and operation. In one embodiment, three wells are used for independent cell culture systems in a cell culture array. In a second aspect, artificial sinusoids with artificial epithelial barriers are provided with just one (optionally shared or multiplexed) fluidic inlet and one (optionally shared or multiplexed) fluidic output, where the medium output also functions as a cellular input. A pneumatic cell loader combined with other components provides a fully automated cell culture system. Magnetic alignment of plate molds provides advantages and ease of molded manufacture.
Abstract translation: 许多新颖的改进的微流体配置以及制造和操作的系统和方法。 在一个实施方案中，三个孔用于细胞培养物阵列中的独立细胞培养系统。 在第二方面，具有人造上皮障碍物的人造正弦曲线仅提供一个（可选地共享或多路复用）流体入口和一个（可选地共享或多路复用）流体输出，其中介质输出也用作蜂窝输入。 与其他组件组合的气动电池加载器提供了完全自动化的细胞培养系统。 板模具的磁性排列提供了模制制造的优点和容易性。
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公开(公告)号：US10526572B2
公开(公告)日：2020-01-07
申请号：US15459332
申请日：2017-03-15
Applicant: EMD Millipore Corporation
Inventor： Paul J. Hung , Philip J. Lee
Abstract: Microfluidic devices, systems, and methods providing for an invasion assay using microfluidic culture systems.
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公开(公告)号：US11034925B2
公开(公告)日：2021-06-15
申请号：US16713117
申请日：2019-12-13
Applicant: EMD Millipore Corporation
Inventor： Paul J. Hung , Philip J. Lee
Abstract: Microfluidic devices, systems, and methods providing for an invasion assay using microfluidic culture systems.
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公开(公告)号：US20170267961A1
公开(公告)日：2017-09-21
申请号：US15459332
申请日：2017-03-15
Applicant: EMD Millipore Corporation
Inventor： Paul J. Hung , Philip J. Lee
Abstract: Microfluidic devices, systems, and methods providing for an invasion assay using microfluidic culture systems.
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