CHEMOMETRICS FOR NEAR INFRARED SPECTRAL ANALYSIS
    313.
    发明申请
    CHEMOMETRICS FOR NEAR INFRARED SPECTRAL ANALYSIS 审中-公开
    近红外光谱分析的化学计量学

    公开(公告)号:US20130080070A1

    公开(公告)日:2013-03-28

    申请号:US13624614

    申请日:2012-09-21

    Abstract: This disclosure concerns systems and methods for identifying and selecting a more accurate chemometric model for the analysis of specific plant samples via near infrared spectrometry. This disclosure further concerns the use of such systems and methods to identify characteristics and traits of interest in plants and plant samples, for example, to facilitate selective breeding, quality control, and/or inventory control.

    Abstract translation: 本公开涉及用于通过近红外光谱法鉴定和选择用于分析特定植物样品的更准确的化学计量模型的系统和方法。 本公开还涉及使用这样的系统和方法来鉴定植物和植物样品中的感兴趣的特征和特征,例如促进选择性育种,质量控制和/或库存控制。

    Apparatus and method for measuring the properties of petroleum fractions and pure hydrocarbon liquids by light refraction
    315.
    发明授权
    Apparatus and method for measuring the properties of petroleum fractions and pure hydrocarbon liquids by light refraction 有权
    通过光折射测量石油馏分和纯烃液体的性质的装置和方法

    公开(公告)号:US08332162B2

    公开(公告)日:2012-12-11

    申请号:US13366257

    申请日:2012-02-03

    CPC classification number: G01N21/4133 G01N33/28 G01N2201/129

    Abstract: A Method and apparatus to accurately measure and display various properties of hydrocarbons and petroleum factions for a small volume of sample in a short period of time in one test with less cost and energy for the analysis by the method of light refection. The refraction of light through the sample is measured and compared to the refraction f the light through vacuum by the apparatus. The method of the invention comprises a property estimation from the apparatus to output a property estimate value. The property estimation means is equipped with a property estimation model for evaluating the property estimate value outputted from the property estimation model. The method is incorporated into standard or otherwise any refractive index test apparatus or refractometer to provide accurate measure of the thermodynamic and transport properties of pure hydrocarbons and undefined multicomponent mixtures such as petroleum factions.

    Abstract translation: 一种用于在一次测试中在短时间内精确测量和显示少量样品的碳氢化合物和石油派系的各种性质的方法和装置,具有较少的成本和能量用于通过光反射的方法进行分析。 测量通过样品的光的折射,并与通过该装置的真空的光的折射进行比较。 本发明的方法包括从设备输出属性估计值的属性估计。 属性估计装置配备有用于评估从属性估计模型输出的属性估计值的属性估计模型。 该方法结合到标准或其他任何折射率测试装置或折射计中,以提供纯烃和未定义的多组分混合物如石油派系的热力学和运输特性的精确测量。

    Fiber optic based detection of autofluorescent bacterial pathogens
    316.
    发明授权
    Fiber optic based detection of autofluorescent bacterial pathogens 有权
    光纤检测自身荧光细菌病原体

    公开(公告)号:US08280471B2

    公开(公告)日:2012-10-02

    申请号:US11954867

    申请日:2007-12-12

    Abstract: Disclosed are methods and devices for continuous in vivo monitoring of a potential bacterial infection site. Disclosed devices may be utilized to alert patients and/or health care providers to the presence of pathogenic bacteria at an early stage of a hospital acquired infection, thereby providing for earlier intervention. Disclosed methods utilize optical fibers to deliver an excitation signal to an area in which pathogenic bacteria may exist. In the presence of the excitation signal, bacterial pathogens may autofluoresce with a unique spectral signature. Upon generation of a fluorescent emission, an optically detectable emission signal may be transmitted to a detection/analysis device. Analysis of the characteristics of the emission signal produced in response to the excitation signal may be used to determine the presence or concentration of pathogens at the site of inquiry, following which real time information may be transmitted to medical personnel via a wireless transmission system.

    Abstract translation: 公开了用于连续体内监测潜在细菌感染部位的方法和装置。 可以利用公开的装置来在医院获得性感染的早期阶段向患者和/或保健提供者警告病原菌的存在,从而提供早期干预。 公开的方法利用光纤将激发信号传递到可能存在病原菌的区域。 在激发信号的存在下,细菌病原体可以自发荧光具有独特的光谱特征。 在产生荧光发射时,光学上可检测的发射信号可被传送到检测/分析装置。 对响应于激发信号产生的发射信号的特性的分析可以用于确定在询问现场的病原体的存在或集中,随后可以通过无线传输系统向医务人员传送实时信息。

    System for Noninvasive Determination of Analytes in Tissue
    317.
    发明申请
    System for Noninvasive Determination of Analytes in Tissue 有权
    无创测定组织中分析物的系统

    公开(公告)号:US20120197096A1

    公开(公告)日:2012-08-02

    申请号:US13444989

    申请日:2012-04-12

    Abstract: An apparatus and method for noninvasive determination of analyte properties of human tissue by quantitative infrared spectroscopy to clinically relevant levels of precision and accuracy. The system includes subsystems optimized to contend with the complexities of the tissue spectrum, high signal-to-noise ratio and photometric accuracy requirements, tissue sampling errors, calibration maintenance problems, and calibration transfer problems. The subsystems can include an illumination/modulation subsystem, a tissue sampling subsystem, a data acquisition subsystem, a computing subsystem, and a calibration subsystem. The invention can provide analyte property determination and identity determination or verification from the same spectroscopic information, making unauthorized use or misleading results less likely than in systems that use separate analyte and identity determinations. The invention can be used to control and monitor individuals accessing controlled environments.

    Abstract translation: 一种用于通过定量红外光谱法非临床确定人体组织的分析物质的临床相关水平的精确度和准确度的装置和方法。 该系统包括优化的子系统,以应对组织光谱的复杂性,高信噪比和光度精度要求,组织采样误差,校准维护问题和校准转移问题。 子系统可以包括照明/调制子系统,组织采样子系统,数据采集子系统,计算子系统和校准子系统。 本发明可以提供来自相同光谱信息的分析物质性质确定和鉴别确定或验证,使得未经授权的使用或误导结果比使用单独的分析物和身份确定的系统更不可能。 本发明可用于控制和监视访问受控环境的个人。

    Apparatus and Method for Measuring the Properties of Petroleum Fractions and Pure Hydrocarbon Liquids by Light Refraction
    318.
    发明申请
    Apparatus and Method for Measuring the Properties of Petroleum Fractions and Pure Hydrocarbon Liquids by Light Refraction 有权
    通过光折射测量石油馏分和纯烃液体的性质的装置和方法

    公开(公告)号:US20120143517A1

    公开(公告)日:2012-06-07

    申请号:US13366257

    申请日:2012-02-03

    CPC classification number: G01N21/4133 G01N33/28 G01N2201/129

    Abstract: A Method and apparatus to accurately measure and display various properties of hydrocarbons and petroleum factions for a small volume of sample in a short period of time in one test with less cost and energy for the analysis by the method of light refection. The refraction of light through the sample is measured and compared to the refraction f the light through vacuum by the apparatus. The method of the invention comprises a property estimation from the apparatus to output a property estimate value. The property estimation means is equipped with a property estimation model for evaluating the property estimate value outputted from the property estimation model. The method is incorporated into standard or otherwise any refractive index test apparatus or refractometer to provide accurate measure of the thermodynamic and transport properties of pure hydrocarbons and undefined multicomponent mixtures such as petroleum factions.

    Abstract translation: 一种用于在一次测试中在短时间内精确测量和显示少量样品的碳氢化合物和石油产品的各种性质的方法和装置,具有较少的成本和能量用于通过光反射的方法进行分析。 测量通过样品的光的折射,并与通过该装置的真空的光的折射进行比较。 本发明的方法包括从设备输出属性估计值的属性估计。 属性估计装置配备有用于评估从属性估计模型输出的属性估计值的属性估计模型。 该方法结合到标准或其他任何折射率测试装置或折射计中,以提供纯烃和未定义的多组分混合物如石油派系的热力学和运输特性的精确测量。

    Monitoring, Detecting and Quantifying Chemical Compounds in a Sample
    319.
    发明申请
    Monitoring, Detecting and Quantifying Chemical Compounds in a Sample 有权
    监测,检测和定量样品中的化合物

    公开(公告)号:US20120065948A1

    公开(公告)日:2012-03-15

    申请号:US12880903

    申请日:2010-09-13

    Abstract: Described are computer-based methods and apparatuses, including computer program products, for monitoring, detecting, and quantifying chemical compounds in a sample. A sample measurement comprising a digitized spectroscopic profile is received. A multivariate multistage background model comprising a first model that models a first time effect, a second model that models a second time effect that is different than the first time effect, or both is calculated. A background corrected sample measurement based on the sample measurement and the multivariate multistage background model is generated. A multivariate multistage library search, fault detection, and quantification algorithm is executed to identify one or more primary chemicals in the background corrected sample measurement. The search, detection, and quantification algorithm includes identifying one or more candidate chemicals in the background corrected sample measurement based on a multivariate statistical process control and identifying and quantifying a first primary chemical based on a focused chemical evaluation of the one or more candidate chemicals.

    Abstract translation: 描述了基于计算机的方法和装置,包括用于监测,检测和量化样品中的化合物的计算机程序产品。 接收包括数字化光谱轮廓的样本测量。 计算包括对第一时间效应建模的第一模型,对与第一时间效应不同的第二时间效应建模的第二模型或两者的多变量多阶段背景模型。 生成基于样本测量和多变量多级背景模型的背景校正样本测量。 执行多变量多级库搜索,故障检测和量化算法来识别背景校正样本测量中的一种或多种主要化学品。 搜索,检测和定量算法包括基于多变量统计过程控制来鉴定背景校正样本测量中的一种或多种候选化学品,并且基于所述一种或多种候选化学品的聚焦化学评估来鉴定和量化第一主要化学品。

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