公开(公告)号：US09037243B2

公开(公告)日：2015-05-19

申请号：US14514817

申请日：2014-10-15

Applicant: Greatbatch Ltd.

Inventor： Shahn S. Sage

IPC: A61N1/375 ,  H01R13/187 ,  A61N1/05 ,  H01R13/33 ,  A61N1/36 ,  H01R24/58 ,  H01R107/00

CPC classification number: A61N1/3752 ,  A61N1/0551 ,  A61N1/3605 ,  A61N1/36125 ,  H01R13/187 ,  H01R13/33 ,  H01R24/58 ,  H01R2107/00 ,  H01R2201/12 ,  Y10S439/909 ,  Y10T29/49117

Abstract: A low-insertion force electrical connector for implantable medical devices includes a housing with a pair of opposing sidewalls each with center openings oriented generally concentrically around a center axis. An inner coil is located in a recess with a coil axis generally co-linear with the center axis of the center openings. The inner coil includes an outer diameter less than a recess diameter, and an inner diameter greater than a center opening diameter. An outer coil is threaded onto the inner coil. The outer coil has an outer diameter less than the recess diameter, and an inner diameter less than the center opening diameter. The outer coil is radially expanded within the recess in response to engagement with contact rings on the implantable medical device, such that the outer diameter of the outer coil is at least equal to the recess diameter.

公开(公告)号：US09002476B2

公开(公告)日：2015-04-07

申请号：US14024668

申请日：2013-09-12

Applicant: Greatbatch Ltd.

Inventor： Jesse Geroy ,  John M. Swoyer

IPC: A61N1/05 ,  H01B7/04

CPC classification number: A61N1/0551 ,  A61N1/05 ,  H01B7/048 ,  Y10T29/49169

Abstract: A biomedical conductor assembly adapted for at least partial insertion in a living body. The conductor assembly includes a plurality of the first electrical conductors each covered with an insulator and helically wound in a first direction to form an inner coil with a lumen. A plurality of second electrical conductors each including a plurality of un-insulated wires twisted in a ropelike configuration around a central axis to form a plurality of cables. Each cable is covered with an insulator and helically wound in a second opposite direction forming an outer coil in direct physical contact with the inner coil. The inner and outer coils are covered by an insulator. A method of making the conductor assembly and implanting a neurostimulation system is also disclosed.

Abstract translation: 适用于至少部分插入生物体内的生物医学导体组件。 导体组件包括多个第一电导体，每个第一电导体覆盖有绝缘体并沿第一方向螺旋缠绕以形成具有内腔的内部线圈。 多个第二电导体，每个第二电导体包括围绕中心轴线缠绕成线形构造的多条绝缘线，以形成多条电缆。 每个电缆被绝缘体覆盖，并且在第二相反方向上螺旋缠绕，形成与内部线圈直接物理接触的外部线圈。 内外线圈由绝缘体覆盖。 还公开了制造导体组件和植入神经刺激系统的方法。

公开(公告)号：US20150079836A1

公开(公告)日：2015-03-19

申请号：US14483233

申请日：2014-09-11

Applicant: Greatbatch Ltd.

Inventor： Elliot Bridgeman ,  Lawrence Kane

IPC: A61N1/05 ,  H01R13/629 ,  H01R13/46

CPC classification number: A61N1/056 ,  A61N1/3752 ,  H01R13/33 ,  H01R24/58 ,  H01R2107/00 ,  H01R2201/00 ,  H01R2201/12

Abstract: In various examples, a connector apparatus includes at least one connector including an integral conductor and an encapsulation housing. The at least one connector includes a contact portion and a tail portion, wherein the contact portion is configured to selectively accept and electrically couple to a therapy delivery element. The tail portion extends outwardly from the contact portion. The encapsulation housing at least partially surrounds at least some of the contact portion of the conductor. The encapsulation housing includes an inner surface, wherein at least some of the contact portion of the conductor extends from the inner surface of the encapsulation housing. With a contact of the therapy delivery element disposed within the encapsulation housing, the conductor is configured to contact and electrically couple with the contact of the therapy delivery element.

Abstract translation: 在各种示例中，连接器装置包括至少一个包括整体导体和封装壳体​​的连接器。 所述至少一个连接器包括接触部分和尾部部分，其中所述接触部分构造成选择性地接受并电耦合到治疗递送元件。 尾部从接触部分向外延伸。 封装壳体至少部分地围绕导体的接触部分中的至少一些。 封装壳体包括内表面，其中导体的接触部分中的至少一些从封装壳体的内表面延伸。 通过设置在封装壳体内的治疗递送元件的接触，导体构造成与治疗递送元件的接触部接触并电耦合。

公开(公告)号：US20150032193A1

公开(公告)日：2015-01-29

申请号：US14514817

申请日：2014-10-15

Applicant: Greatbatch Ltd.

Inventor： Shahn S. Sage

IPC: A61N1/375 ,  A61N1/36

CPC classification number: A61N1/3752 ,  A61N1/0551 ,  A61N1/3605 ,  A61N1/36125 ,  H01R13/187 ,  H01R13/33 ,  H01R24/58 ,  H01R2107/00 ,  H01R2201/12 ,  Y10S439/909 ,  Y10T29/49117

Abstract: A low-insertion force electrical connector for implantable medical devices includes a housing with a pair of opposing sidewalls each with center openings oriented generally concentrically around a center axis. An inner coil is located in a recess with a coil axis generally co-linear with the center axis of the center openings. The inner coil includes an outer diameter less than a recess diameter, and an inner diameter greater than a center opening diameter. An outer coil is threaded onto the inner coil. The outer coil has an outer diameter less than the recess diameter, and an inner diameter less than the center opening diameter. The outer coil is radially expanded within the recess in response to engagement with contact rings on the implantable medical device, such that the outer diameter of the outer coil is at least equal to the recess diameter.

Abstract translation: 用于可植入医疗装置的低插入力电连接器包括具有一对相对侧壁的壳体，每个侧壁均具有围绕中心轴线同心取向的中心开口。 内部线圈位于具有与中心开口的中心轴线大致共线的线圈轴线的凹部中。 内部线圈包括小于凹部直径的外径和大于中心开口直径的内径。 外部线圈螺纹连接到内部线圈上。 外部线圈的外径小于凹部直径，内径小于中心开口直径。 外部线圈响应于与可植入医疗装置上的接触环的接合而在凹部内径向扩张，使得外部线圈的外径至少等于凹部直径。

公开(公告)号：US20150032113A1

公开(公告)日：2015-01-29

申请号：US14332481

申请日：2014-07-16

Applicant: Greatbatch Ltd.

Inventor： Daniel L. Anderson

IPC: A61B17/17

CPC classification number: A61B17/1764 ,  A61B17/15 ,  A61B17/155 ,  A61B17/8863 ,  A61B2017/568

Abstract: In various examples, an apparatus includes an instrument body including a protrusion configured to be sized according to an anatomy of a bone of a patient. A guide is configured to guide an aspect of a resection procedure of the bone, wherein the protrusion, when sized, is configured to abut the patient's bone to maintain the instrument body in a first position with respect to the bone during at least part of the resection procedure.

Abstract translation: 在各种示例中，一种装置包括：仪器主体，其包括突起，所述突起构造成根据患者的骨骼的解剖结构来定尺寸。 引导件被构造成引导骨的切除过程的一个方面，其中，当所述突出部的尺寸被设计成邻接所述患者的骨骼时，所述突出部被配置成在所述骨骼的至少一部分期间将所述器械主体相对于所述骨骼保持在第一位置 切除手术。

公开(公告)号：US20150012068A1

公开(公告)日：2015-01-08

申请号：US14321914

申请日：2014-07-02

Applicant: Greatbatch Ltd.

Inventor： Kerry Bradley ,  Les Halberg

IPC: A61N1/36

CPC classification number: A61N1/0551 ,  A61B5/064 ,  A61B8/0841 ,  A61N1/05 ,  A61N1/0553 ,  A61N1/36017 ,  A61N1/36021 ,  A61N1/36071 ,  A61N1/36125 ,  A61N1/36139 ,  A61N1/36146 ,  A61N1/36153 ,  A61N1/37223 ,  A61N1/37235 ,  A61N1/37252 ,  A61N1/3752 ,  A61N1/3787

Abstract: A method of establishing a stimulation treatment protocol includes delivering electrical stimulation to a nerve site of the patient. The electrical stimulation is delivered using a stimulation configuration with respect to one or more of the following: activation of a subset of a plurality of electrodes on a lead, electrode polarity for the activated electrodes, stimulation pulse width, and stimulation pulse amplitude. An action potential evoked from the nerve site in response to the electrical stimulation is measured. The action potential includes a sensory fiber contribution and a motor fiber contribution. Both the sensory fiber contribution and the motor fiber contribution are measured. The delivering and the measuring are repeated for a plurality of cycles. Each cycle is performed using a different stimulation configuration. The stimulation configuration that offers a greatest sensory fiber contribution relative to the motor fiber contribution is recommended as a candidate for optimized stimulation configuration.

Abstract translation: 建立刺激治疗方案的方法包括将电刺激递送到患者的神经部位。 使用关于以下中的一个或多个的刺激配置来递送电刺激：激活引线上的多个电极的子集，激活电极的电极极性，刺激脉冲宽度和刺激脉冲幅度。 测量响应于电刺激从神经部位诱发的动作电位。 动作电位包括感官纤维的贡献和运动纤维的贡献。 测量感官纤维的贡献和运动纤维的贡献。 交付和测量重复多个周期。 每个循环使用不同的刺激配置进行。 作为优化刺激配置的候选者，推荐提供相对于马达纤维贡献的最大感官纤维贡献的刺激配置。

公开(公告)号：US20150012063A1

公开(公告)日：2015-01-08

申请号：US14322394

申请日：2014-07-02

Applicant: Greatbatch Ltd.

Inventor： Joey Chen

IPC: A61N1/36

CPC classification number: A61N1/0551 ,  A61B5/064 ,  A61B8/0841 ,  A61N1/05 ,  A61N1/0553 ,  A61N1/36017 ,  A61N1/36021 ,  A61N1/36071 ,  A61N1/36125 ,  A61N1/36139 ,  A61N1/36146 ,  A61N1/36153 ,  A61N1/37223 ,  A61N1/37235 ,  A61N1/37252 ,  A61N1/3752 ,  A61N1/3787

Abstract: A medical device for providing an electrical stimulation therapy for a patient includes a microcontroller configured to generate a plurality of electrical pulses and a control signal. The medical device includes a stimulation driver coupled to the microcontroller. The stimulation driver is configured to amplify the electrical pulses into amplified electrical pulses to be delivered to the patient as a part of the electrical stimulation therapy. The medical device includes a battery configured to supply a first voltage. The medical device includes a voltage up-converter coupled between the battery and the stimulation driver. The voltage up-converter is configured to convert, in response to the control signal from the microcontroller, the first voltage to a compliance voltage for the stimulation driver. The compliance voltage is a fraction of the first voltage, and the fraction is greater than 1.

Abstract translation: 用于为患者提供电刺激治疗的医疗装置包括被配置为产生多个电脉冲和控制信号的微控制器。 医疗设备包括耦合到微控制器的刺激驱动器。 刺激驱动器被配置为将电脉冲放大为放大的电脉冲，作为电刺激治疗的一部分被递送给患者。 医疗装置包括被配置为提供第一电压的电池。 医疗设备包括耦合在电池和刺激驱动器之间的电压上变频器。 电压上变频器被配置为响应于来自微控制器的控制信号将第一电压转换为用于刺激驱动器的顺应性电压。 顺应电压是第一电压的一部分，分数大于1。

公开(公告)号：US20140343629A1

公开(公告)日：2014-11-20

申请号：US14279925

申请日：2014-05-16

Applicant: Greatbatch Ltd.

Inventor： Norbert Kaula ,  Yohannes Iyassu

IPC: A61N1/372

CPC classification number: A61N1/37247 ,  A61N1/36185 ,  G06F3/0482 ,  G06F3/0484 ,  G06F3/04842 ,  G06F3/04847 ,  G06F3/0485 ,  G06F19/00 ,  G06F19/3481 ,  G16H20/30 ,  G16H40/63 ,  G16H50/50

Abstract: A method of displaying impedance information of an implantable medical device is provided. One or more impedance values are received over a period of time for a plurality of channels. The channels may each include an electrode contact on an implantable lead. A graph is displayed that illustrates a variation of the impedance values over at least a portion of the period of time for one or more of the channels. A visual landscape that is representative of the impedance values for the plurality of channels is also displayed.

Abstract translation: 提供一种显示可植入医疗装置的阻抗信息的方法。 在多个通道的一段时间内接收一个或多个阻抗值。 通道可以各自包括在可植入引线上的电极接触。 显示了图表，其示出了一个或多个通道的至少一段时间内的阻抗值的变化。 还显示代表多个通道的阻抗值的视觉景观。

公开(公告)号：US20140323972A1

公开(公告)日：2014-10-30

申请号：US14330033

申请日：2014-07-14

Applicant: Greatbatch Ltd.

Inventor： Terry D. Daglow

IPC: A61M25/04 ,  A61N1/05 ,  A61N1/36

CPC classification number: A61M25/04 ,  A61M2005/1416 ,  A61M2039/0223 ,  A61M2039/0261 ,  A61N1/05 ,  A61N1/0558 ,  A61N1/3605

Abstract: An anchor sleeve for securing a therapy delivery element, such as a stimulation lead or catheter, within a living body, that includes an inner sleeve with pre-formed locations of weakness that facilitate localized deformation. The anchor includes a deformable outer sleeve with a primary lumen extending along an axis. The outer surface of the outer sleeve includes a plurality of suture grooves oriented generally concentric to the axis. The inner sleeve includes a plurality of beams connected at deflection regions arranged around a secondary lumen. The inner sleeve is located in the primary lumen adjacent to the suture grooves so that the secondary lumen is generally concentric with the primary lumen. A plurality of locations of weakness are preformed in each of the beams to facilitate localized deformation in response to a radially inward force applied around the suture grooves by a suture material.

Abstract translation: 用于固定生物体内的治疗递送元件（例如刺激引线或导管）的锚定套筒，其包括具有促进局部变形的预先形成的弱点位置的内套筒。 锚固件包括具有沿轴线延伸的主腔的可变形外套筒。 外套筒的外表面包括大致与轴线同心取向的多个缝合槽。 内套筒包括连接在布置在次内腔周围的偏转区域的多个梁。 内套筒位于与缝合槽相邻的主腔内，使得第二内腔与主腔大致同心。 在每个梁中形成多个弱点位置，以便响应于通过缝合材料施加在缝合线槽周围的径向向内的力而促进局部变形。

公开(公告)号：US08868199B2

公开(公告)日：2014-10-21

申请号：US13973363

申请日：2013-08-22

Applicant: Greatbatch Ltd.

Inventor： Norbert Kaula ,  Yohannes Iyassu ,  Carl Mosley ,  Scott Drees

IPC: A61N1/00 ,  A61N1/372 ,  G06F19/00 ,  G06T19/20 ,  A61N1/36

CPC classification number: A61N1/37252 ,  A61N1/36128 ,  A61N1/37247 ,  G06F19/00 ,  G06T19/20 ,  G06T2210/41 ,  G06T2219/2012 ,  G06T2219/2021 ,  G16H10/60

Abstract: The present disclosure involves a method of data-reducing and storing a sensation map. A sensation map associated with a patient is provided. The sensation map includes a graphical depiction of a sensation experienced by the patient. The sensation may be pain or paresthesia experienced by the patient in response to an electrical stimulation therapy. A data file is generated. The data file has a data size less than a data size of the sensation map. The data file contains digital information allowing a reconstruction of the sensation map. Electronic communication is then established with an implanted medical device located inside the patient's body. Thereafter, the data file is sent to the implanted medical device for storage. The stored data files are retrievable by another clinician programmer later to reconstruct the sensation map.

Abstract translation: 本公开涉及一种数据减少和存储感觉图的方法。 提供与患者相关联的感觉图。 感觉图包括患者经历的感觉的图形描绘。 感觉可能是患者对电刺激治疗的反应而感到疼痛或感觉异常。 生成数据文件。 数据文件的数据大小小于感觉图的数据大小。 数据文件包含允许重建感觉图的数字信息。 然后与位于患者体内的植入式医疗装置建立电子通信。 此后，将数据文件发送到植入的医疗装置进行存储。 存储的数据文件可以由另一位临床医师程序员随后检索以重构感觉图。