公开(公告)号：US07151448B2

公开(公告)日：2006-12-19

申请号：US10272069

申请日：2002-10-16

申请人： David Henderson ,  Gordon Henderson ,  Jerry Henderson

发明人： David Henderson ,  Gordon Henderson ,  Jerry Henderson

IPC分类号： B60R25/10

CPC分类号： H04N7/18 ,  G06Q10/087

摘要： There is provided a monitoring system for remotely monitoring an item or activity, the monitoring system including a recording device for recording a visual record of the item, a communicator for communicating the visual record, and a security device for controlling access to the monitoring system. Also provided is a method of remotely monitoring an item by recording a digital image of the item, communicating the digital image of the item through a communication system, and accessing the digital image using a secured access device.

公开(公告)号：US07147666B1

公开(公告)日：2006-12-12

申请号：US08979097

申请日：1997-11-26

申请人： Bernard Francis Grisoni

发明人： Bernard Francis Grisoni

IPC分类号： A61F2/02

CPC分类号： A61F2/28 ,  A61F2/4601 ,  A61F2002/2817 ,  A61F2002/30062 ,  A61F2002/30153 ,  A61F2002/30154 ,  A61F2002/30156 ,  A61F2002/30261 ,  A61F2002/3028 ,  A61F2002/30677 ,  A61F2002/30785 ,  A61F2002/30789 ,  A61F2002/30808 ,  A61F2002/30812 ,  A61F2002/30957 ,  A61F2210/0004 ,  A61F2230/0019 ,  A61F2230/0021 ,  A61F2230/0023 ,  A61F2230/0063 ,  A61F2230/0082 ,  A61F2310/00293 ,  A61L27/12 ,  A61L27/425 ,  A61L27/46 ,  A61L27/56 ,  A61L27/58

摘要： A monolithic bioresorbable implant includes optimally designed openings to treat tissue disorders or drug delivery. Preferably, the implant is made from calcium salts. A method of filling a recipient treatment site includes the step of disposing the monolithic bioresorbable implant into the site.

摘要翻译： 整体式生物可吸收植入物包括最佳设计的开口以治疗组织紊乱或药物递送。 优选地，植入物由钙盐制成。 填充受体治疗部位的方法包括将单片生物可再吸收植入物置于该部位中的步骤。

公开(公告)号：US06989158B1

公开(公告)日：2006-01-24

申请号：US10019192

申请日：2000-06-23

申请人： Kattesh V. Katti ,  Wynn A. Volkert ,  Timothy Hoffman

发明人： Kattesh V. Katti ,  Wynn A. Volkert ,  Timothy Hoffman

IPC分类号： A61K31/28 ,  A61K33/24

CPC分类号： A61K31/28

摘要： There is provided a complex for use as a therapeutic pharmaceutical, the complex has a ligand containing at least one hydroxyalkyl phosphine donor group bound to a gold atom to form a stable gold-ligand complex. Also provided is a method of treating cancer by administering an effective amount of a complex having a ligand of at least one hydroxyalkyl phosphine group bound to a gold atom to form a stable gold-ligand complex. Also provided is a method of preventing the metastasis of cancer and arresting cell growth by administering an effective amount of a complex having a ligand of at least one hydroxyalkyl phosphine group bound to a gold atom to form a stable gold-ligand complex.

摘要翻译： 提供了用作治疗药物的复合物，该配合物具有含有至少一个与金原子结合的羟烷基膦供体基团以形成稳定的金 - 配体络合物的配体。 还提供了通过施用有效量的具有与金原子结合的至少一个羟基烷基膦基团的配体的络合物以形成稳定的金 - 配体络合物来治疗癌症的方法。 还提供了通过施用有效量的具有与金原子结合的至少一个羟烷基膦基配体的配合物以形成稳定的金 - 配体络合物的方法来防止癌症转移和阻止细胞生长的方法。

公开(公告)号：US06921526B2

公开(公告)日：2005-07-26

申请号：US10122611

申请日：2002-04-12

申请人： Timothy J. Hoffman ,  Wynn A. Volkert ,  Ning Li ,  Gary Sieckman ,  Chrys-Ann Higginbotham

发明人： Timothy J. Hoffman ,  Wynn A. Volkert ,  Ning Li ,  Gary Sieckman ,  Chrys-Ann Higginbotham

IPC分类号： G01N33/566 ,  A61K38/00 ,  A61K51/00 ,  A61K51/08 ,  A61P35/00 ,  C07F5/00 ,  C07F15/00 ,  C07K7/06 ,  C07K7/08 ,  C07K14/575 ,  A61M36/14

CPC分类号： A61K51/088 ,  A61K38/00 ,  C07F5/003 ,  C07F15/008 ,  C07K7/086 ,  C07K14/57572

摘要： A compound for use as a therapeutic or diagnostic radiopharmaceutical includes a group capable of complexing a medically useful metal attached to a moiety which is capable of binding to a gastrin releasing peptide receptor. A method for treating a subject having a neoplastic disease includes administering to the subject an effective amount of a radiopharmaceutical having a metal chelated with a chelating group attached to a moiety capable of binding to a gastrin releasing peptide receptor expressed on tumor cells with subsequent internalization inside of the cell. A method of forming a therapeutic or diagnostic compound includes reacting a metal synthon with a chelating group covalently linked with a moiety capable of binding a gastrin releasing peptide receptor.

摘要翻译： 用作治疗或诊断性放射性药物的化合物包括能够使与能够结合胃泌素释放肽受体的部分连接的医学上有用的金属络合的基团。 用于治疗患有肿瘤疾病的受试者的方法包括向受试者施用有效量的具有与螯合基螯合的金属的放射性药物，所述螯合基团连接到能够结合肿瘤细胞上表达的胃泌素释放肽受体的部分，随后内化 的细胞。 形成治疗或诊断化合物的方法包括使金属合成酶与能够结合胃泌素释放肽受体的部分共价连接的螯合基团反应。

公开(公告)号：US12009109B2

公开(公告)日：2024-06-11

申请号：US17127352

申请日：2020-12-18

申请人： OptimDosing LLC

发明人： David Inwald ,  Kenneth I. Kohn

IPC分类号： G16H70/40 ,  A61K45/06 ,  G16H10/60 ,  G16H20/10 ,  G16H20/60 ,  G16H70/20

CPC分类号： G16H70/40 ,  A61K45/06 ,  G16H10/60 ,  G16H20/10 ,  G16H20/60 ,  G16H70/20

摘要： A method of dosing cancer therapies, by collecting patient data including cancer therapies/drugs to be taken, analyzing the data in view of dosing criteria established based on outside data, and determining a dose for each cancer therapy/drug taken. A logic engine for dosing cancer therapies, including an algorithm stored on non-transitory computer readable media for collecting clinical trial data to establish criteria for dosing cancer therapies/drugs to a single patient and patient data and storing the clinical trial data and patient data in a database, analyzing the patient data in view of criteria established from the clinical trial data, and determining a dose for each cancer therapy/drug. A method of adjusting treatment of a cancer patient.

公开(公告)号：US11596638B2

公开(公告)日：2023-03-07

申请号：US17060443

申请日：2020-10-01

申请人： Mind Medicine, Inc.

发明人： Scott Freeman ,  Stots B. Reele ,  Jeanne Bonelle

IPC分类号： A61K31/55 ,  A61P25/30 ,  A61K9/00

摘要： A composition for treating substance use disorders of an effective amount of 18-Methoxycoronaridine salt (18-MC) in a pharmaceutical carrier. A method of treating substance use disorders, by administering an effective amount of 18-Methoxycoronaridine salt (18-MC) in a pharmaceutical carrier to an individual and preventing substance abuse in the individual. A method of preventing addictive behavior in an individual. A method of preventing craving in an individual. A composition of a metabolite of 18-MC salt. A method of treating substance use disorders by administering an effective amount of a metabolite of 18-MC salt in a pharmaceutical carrier to an individual and preventing substance abuse in the individual. A composition having various pharmacokinetic profiles as shown in the Figures.

公开(公告)号：US11301808B2

公开(公告)日：2022-04-12

申请号：US15822492

申请日：2017-11-27

申请人： Jules T. Mitchel ,  Joyce B. Hays

发明人： Jules T. Mitchel ,  Joyce B. Hays

IPC分类号： G06Q10/10 ,  G06F16/93 ,  G16H10/20 ,  G16H10/60 ,  G16Z99/00

摘要： A system and method for the collection, capture, processing, storage, and tracking of data for both electronic clinical trial and electronic heath records based upon a single data collection instance, and including data collected by electronic medical devices. Devices and methods for creating certified digital image copies of original documents, including paper source documents for a clinical trial. Devices and methods for ensuring the secure archiving of original electronic documents, including electronic clinical trial source documents, in a secure document storage server.

公开(公告)号：US10980906B2

公开(公告)日：2021-04-20

申请号：US16468770

申请日：2017-12-21

申请人： Miriah Gilliam-Perkins

发明人： Miriah Gilliam-Perkins

IPC分类号： A61L2/24 ,  A61L2/10 ,  A61L2/28

摘要： A germ-reducing pen container including a body having a hollow passageway extending therethrough from an insertion end to a distal end for receiving a pen, the hollow passageway having at least one ultraviolet C light operatively attached thereto, an indicator on an outer surface of the body, and a dispensing mechanism operatively attached at the insertion end for dispensing the pen. A method of reducing germs on a pen, by inserting a pen into a body of a germ-reducing pen container, applying ultraviolet C light to the pen, killing the germs on the pen, indicating that the pen has been cleaned, and dispensing the pen.

公开(公告)号：US10821243B2

公开(公告)日：2020-11-03

申请号：US15623845

申请日：2017-06-15

申请人： Advanced Interactive Response Systems LLC

发明人： Valerie A. Obenchain

IPC分类号： A61M16/00 ,  A61M16/20 ,  F17C13/02 ,  F17C13/04 ,  G08B21/18 ,  G08B21/02 ,  G08B25/08 ,  A62B9/00 ,  G01L19/12 ,  A61M16/06 ,  A61M16/08 ,  A61M16/10 ,  A61M16/16

摘要： A fluid supply warning and communication system including fluid tight engagements being made with tubing having at least one connector end chosen from a universal connector, a twist-on nipple, and a v-shaped end. A gas supply warning and communication system including a first upstream gas path, a second upstream gas path, and a downstream gas path made with tubing having at least one connector end chosen from a universal connector, a twist-on nipple, and a v-shaped end. A method of increasing humidity in a downstream gas path in the gas supply warning and communication system by flowing gas through a downstream gas path tubing that increases humidity to an end use appliance.

公开(公告)号：US10816146B2

公开(公告)日：2020-10-27

申请号：US16900111

申请日：2020-06-12

申请人： Argo Import-Export Ltd.

发明人： Zhang Yingchun

IPC分类号： F21K9/27 ,  F21S4/20 ,  H01R33/96 ,  F21V15/01 ,  F21K9/90 ,  F21V23/06 ,  H05B45/00 ,  F21V23/00 ,  F21V3/06 ,  F21V29/506 ,  F21Y103/10 ,  F21Y115/10 ,  F21K9/278 ,  F21V25/04

摘要： An LED lighting tube including a heat-dissipating tubular envelope having an LED assembly directly affixed to an inner surface of the heat-dissipating tubular envelope. A method of making an LED lighting tube by providing a heat-dissipating tubular envelope, and affixing an LED assembly directly to an inner surface of the heat-dissipating tubular envelope with an adhesive layer. A method of providing heat-dissipation without a heat sink in an LED lighting tube by providing a heat-dissipating tubular envelope, affixing an LED assembly directly to an inner surface of the heat-dissipating tubular envelope with an adhesive layer, and dissipating heat through the heat-dissipating tubular envelope.