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    DEVICE FOR PROCESSING HOMOMORPHICALLY ENCRYPTED DATA
    33.
    发明公开
    DEVICE FOR PROCESSING HOMOMORPHICALLY ENCRYPTED DATA 审中-公开

    公开(公告)号：US20240039694A1

    公开(公告)日：2024-02-01

    申请号：US18254132

    申请日：2021-11-24

    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

    Inventor： Hong YANG ,  Dee Meng KANG ,  Ahmad Qaisar Ahmad AL BADAWI ,  Khin Mi Mi AUNG

    IPC: H04L9/00 ,  G06F9/38 ,  G06F7/72

    CPC classification number: H04L9/008 ,  G06F9/3875 ,  G06F7/724

    Abstract: There is provided a device for processing homomorphically encrypted data. The device includes: inter-line butterfly array blocks, each inter-line butterfly array block including inter-line modulus butterfly units, each inter-line modulus butterfly unit being configured to perform a modulus butterfly operation based on a computation pair of data points received corresponding to a pair of input data points at a same row of a matrix of input data points; intra-line butterfly array blocks, each intra-line butterfly array block including intra-line modulus butterfly units, each intra-line modulus butterfly unit being configured to perform a modulus butterfly operation based on a computation pair of data points received corresponding to a pair of input data points at a same column of the matrix of input data points; and a clock counter communicatively coupled to each inter-line butterfly array block and each intra-line butterfly array block, and configured to output a counter signal for controlling each inter-line butterfly array block and each intra-line butterfly array block to operate with single cycle initiation interval. The matrix of input data points includes columns of input data points, whereby parallel input data points derived from the homomorphically encrypted data are arranged into the columns of input data points. Furthermore, the inter-line butterfly array blocks and the intra-line butterfly array blocks are arranged in series to form a pipeline for processing the matrix of input data points.

    PIEZOELECTRIC DEVICE AND METHOD OF FORMING THE SAME
    34.
    发明公开
    PIEZOELECTRIC DEVICE AND METHOD OF FORMING THE SAME 审中-公开

    公开(公告)号：US20240032429A1

    公开(公告)日：2024-01-25

    申请号：US18044493

    申请日：2021-09-23

    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

    Inventor： Eldwin Jiaqiang NG ,  Nan WANG ,  Srinivas MERUGU ,  Jaibir SHARMA

    IPC: H10N30/20 ,  H10N30/853 ,  H10N30/076

    CPC classification number: H10N30/2047 ,  H10N30/853 ,  H10N30/076

    Abstract: Various embodiments may relate to a piezoelectric device. The piezoelectric device may include a substrate, and a layered stacked arrangement anchored to the substrate. The layered stacked arrangement may include a piezoelectric layer. The stacked arrangement may also include a first electrode on a first side of the piezoelectric layer. The stacked arrangement may further include a second electrode on a second side of the piezoelectric layer opposite the first side. The piezoelectric layer may include a first region including one or more dipole domains of a first type, and one or more dipole domains of a second type. The first electrode may be at least partially in contact with the first region and at least partially in contact with the second region.

    Truncated CRISPR-Cas proteins for DNA targeting
    37.
    发明授权
    Truncated CRISPR-Cas proteins for DNA targeting 有权

    公开(公告)号：US11840694B2

    公开(公告)日：2023-12-12

    申请号：US16342319

    申请日：2017-10-17

    Applicant: NANYANG TECHNOLOGICAL UNIVERSITY ,  AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

    Inventor： Meng How Tan ,  Kean Hean Ooi

    IPC: C12N9/22 ,  C12N15/74 ,  C07K16/12

    CPC classification number: C12N15/746 ,  C07K16/1275 ,  C12N9/22 ,  C12N2310/20

    Abstract: The present invention relates to a polypeptide comprising at least one at least one deletion selected from the group consisting of ΔHNH (Δ775-909), ARuvCIII-b (Δ1002-1074), AREC1-a (Δ510-655), AREC1-b (Δ525-587), AREC1-c (Δ662-710), AREC2 (Δ180-308), AREC2-a (Δ212-244), AREC2-b (Δ244-276), AREC2-c (Δ276-308), AREC2-d (Δ199-283), AREC2-e (Δ198-257), AREC2-f (Δ235-286), AREC2-g (Δ217-266), AREC3 (Δ498-712) and combinations thereof, wherein the position numbering is in accordance with SEQ ID NO: 1 encoding for S. pyogenes Cas9, and wherein the polypeptide has CRISPR-Cas DNA-binding activity. The polypeptide may further comprises a missense mutations selected from G12R, T13K, T13R, N14K, N497K, T657K, T657R, N767K, T770K, T770R, Q920K, Q920R, S1109R, D1135K, D1135R, S1338R and combinations thereof. Also claimed are nucleic acid molecules encoding for said polypeptides, compositions and method of site-directed engineering of a target DNA thereof.

    FUSION PROTEIN FOR BACTERIAL SURFACE DISPLAY
    40.
    发明公开
    FUSION PROTEIN FOR BACTERIAL SURFACE DISPLAY 审中-公开

    公开(公告)号：US20230382958A1

    公开(公告)日：2023-11-30

    申请号：US18245249

    申请日：2021-09-10

    Applicant: Agency for Science, Technology and Research

    Inventor： Richie Pei Kun Tay ,  Siak Wei OW

    IPC: C07K14/335 ,  C12N9/02

    CPC classification number: C07K14/335 ,  C12N9/0089 ,  A61K38/00

    Abstract: The invention relates generally to the field of molecular biology and microbiology. Provided herein is an expression construct encoding a fusion protein. In one embodiment, there is provided an expression construct encoding a fusion protein, the expression construct comprising a nucleic acid encoding a first polypeptide for expression and a second polypeptide derived from the cell wall targeting region of a Lactobacillus plantarum Lys2 autolysin, wherein the first and second polypeptides are joined to form a fusion protein. In a specific embodiment, the second polypeptide comprises the CAD4a domain, which is a truncated domain containing only R1-R3 of the five-repeat SH3_5 domain of the Lys2 autolysin. Provided herein is also a fusion protein and the use of a fusion protein as defined herein.

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