公开(公告)号：US20130253254A1

公开(公告)日：2013-09-26

申请号：US13898680

申请日：2013-05-21

申请人： Arthur E. Uber, III ,  Alan D. Hirschman ,  David M. Griffiths ,  Frederick W. Trombley, III ,  David M. Reilly

发明人： Arthur E. Uber, III ,  Alan D. Hirschman ,  David M. Griffiths ,  Frederick W. Trombley, III ,  David M. Reilly

IPC分类号： A61M5/142 ,  A61J1/20 ,  A61N5/10 ,  A61M5/44

CPC分类号： A61M25/0045 ,  A61J1/2096 ,  A61M5/007 ,  A61M5/1408 ,  A61M5/142 ,  A61M5/1452 ,  A61M5/44 ,  A61M2202/049 ,  A61N5/1001

摘要： A system for delivering fluid to a patient includes a container suitable for holding a fluid and an enclosure to shield the fluid. The system further includes a pump device capable of pumping fluid from the container and delivering the fluid to the patient, and the container adapted to be attachable to the pump device.

摘要翻译： 用于将流体输送到患者的系统包括适于保持流体的容器和用于屏蔽流体的外壳。 该系统还包括能够从容器泵送流体并将流体输送到患者的泵装置，以及适于附接到泵装置的容器。

公开(公告)号：US20130172811A1

公开(公告)日：2013-07-04

申请号：US13772849

申请日：2013-02-21

申请人： Arthur E. Uber, III ,  David M. Griffiths ,  David M. Reilly ,  Alan D. Hirschman ,  Kevin P. Cowan ,  Mark Trocki

发明人： Arthur E. Uber, III ,  David M. Griffiths ,  David M. Reilly ,  Alan D. Hirschman ,  Kevin P. Cowan ,  Mark Trocki

IPC分类号： A61M5/14 ,  A61M5/172

CPC分类号： A61M5/1407 ,  A61M5/14216 ,  A61M5/14236 ,  A61M5/1723 ,  A61M2202/09 ,  B01F7/00258 ,  B01F7/00566 ,  B01F7/00908 ,  B01F7/086 ,  B01F9/103 ,  B01F11/0071 ,  B01F11/0074 ,  B01F11/0082 ,  B01F11/025 ,  B01F13/002 ,  B01F13/0023 ,  B01F13/0818 ,  G06F19/00

摘要： A system for delivering a slurry to a patient includes a fluid, a material that is non-dissolvable or immiscible in the fluid, thereby forming a slurry, a container adapted to contain the slurry and a supernate of the slurry, the container defining an outlet through which the slurry is delivered to the patient, a fluidizing system associated with the container, a pressurizing mechanism adapted to create a pressure to cause the slurry contained within the container to flow for delivery to the patient and a control unit in communication with and adapted to control the fluidizing system and the pressurizing mechanism. The fluidizing system is adapted to effect dilation of the slurry while maintaining at least a portion of the supernate.

摘要翻译： 用于将浆料递送到患者的系统包括流体，在流体中不可溶或不混溶的材料，从而形成浆料，适于容纳浆料的容器和浆料的上清液，容器限定出口 通过其将浆料输送到患者，与容器相关联的流化系统，适于产生压力以使容纳在容器内的浆液流动以输送到患者的加压机构，以及与该患者连接并适应的控制单元 以控制流化系统和加压机构。 流化系统适于在保持至少一部分上清液的同时实现浆料的扩张。

公开(公告)号：US08470298B2

公开(公告)日：2013-06-25

申请号：US10798876

申请日：2004-03-11

申请人： Arthur E Uber, III ,  David M Griffiths

发明人： Arthur E Uber, III ,  David M Griffiths

IPC分类号： A61B8/00 ,  A61K49/00

CPC分类号： A61K49/223 ,  A61B8/4281 ,  A61M5/007 ,  A61M5/142 ,  A61M5/145 ,  A61M5/165 ,  A61M5/16831 ,  A61M2005/006 ,  A61M2205/11 ,  A61M2230/30

摘要： An apparatus, system or method enables microbubbles to be created on demand for use as the contrast agent within a contrast medium administrable to a patient for purposes of a medical procedure. The system comprises a reservoir, a pressurizing device, a microbubble generator, and a controller. The reservoir stores a liquid. The pressurizing device conveys the liquid, along with the medium formed therewith, through the system. The microbubble generator is used to create the microbubbles within the liquid to form the medium. The microbubble generator has an inlet for receiving the liquid and an outlet for communication of the medium to the patient. The controller controls the operation of the system so that the microbubbles created by the microbubble generator are generated according to the demands of the medical procedure and are administrable within the medium to the patient.

摘要翻译： 一种装置，系统或方法使得可以根据需要创建微泡，以用作可用于医疗程序的患者的造影剂中的造影剂。 该系统包括储存器，加压装置，微泡发生器和控制器。 储存器储存液体。 加压装置与其形成的介质一起输送液体通过该系统。 微泡发生器用于在液体内产生微泡以形成介质。 微泡发生器具有用于接收液体的入口和用于将介质与患者通信的出口。 控制器控制系统的操作，使得由微泡发生器产生的微泡根据医疗程序的要求产生，并且可以在介质内向患者施用。

公开(公告)号：US20110209764A1

公开(公告)日：2011-09-01

申请号：US12996520

申请日：2009-06-05

申请人： Arthur E. Uber ,  Mark Trocki ,  Marc A. Mabie ,  Larry McCutchan ,  George L. Siddoway ,  Kevin P. Cowan ,  Lisa M. Coates ,  John F. Kalafut ,  Aaron Hughes ,  David M. Griffiths ,  Peter Twichell ,  Julie Gulick

发明人： Arthur E. Uber ,  Mark Trocki ,  Marc A. Mabie ,  Larry McCutchan ,  George L. Siddoway ,  Kevin P. Cowan ,  Lisa M. Coates ,  John F. Kalafut ,  Aaron Hughes ,  David M. Griffiths ,  Peter Twichell ,  Julie Gulick

IPC分类号： F17D3/00 ,  B65D25/02

CPC分类号： A61N5/1007 ,  A61M5/007 ,  A61M5/16827 ,  A61M5/1785 ,  A61M2005/1402 ,  A61M2202/0225 ,  A61M2202/049 ,  A61M2206/11 ,  A61M2206/18 ,  Y10T137/0318

摘要： A hazardous fluid transport container and a hazardous fluid delivery system are disclosed. The hazardous fluid transport container includes a housing enclosing an at least partially shielded enclosure. First and second fluid path elements are disposed within the housing, with the first fluid path element and second fluid path element fluidly coupled together. A pump unit may be provided for dispensing fluid from the first and second fluid path elements optionally into a third fluid path element. Also, methods for priming the hazardous fluid transport container and for mitigating laminar flow injection bolus spreading are disclosed. Additionally, disclosed is a radioactive fluid transport container for a syringe or other container. The radioactive fluid transport container allows the syringe or container to be used in an injection procedure without removal from the container.

摘要翻译： 公开了一种危险的流体输送容器和危险流体输送系统。 危险流体输送容器包括封闭至少部分屏蔽的外壳的壳体。 第一和第二流体通道元件设置在壳体内，第一流体路径元件和第二流体路径元件流体耦合在一起。 可以提供泵单元，用于将流体从第一和第二流体路径元件任选地分配到第三流体路径元件中。 此外，公开了用于引燃危险流体输送容器和减轻层流注射团块扩散的方法。 此外，公开了一种用于注射器或其他容器的放射性流体输送容器。 放射性流体输送容器允许注射器或容器在注射过程中使用而不从容器中取出。

公开(公告)号：US07996381B2

公开(公告)日：2011-08-09

申请号：US12254318

申请日：2008-10-20

申请人： Arthur E. Uber, III ,  John P. Friel ,  David M. Griffiths

发明人： Arthur E. Uber, III ,  John P. Friel ,  David M. Griffiths

IPC分类号： G06F17/30

CPC分类号： G06F19/325 ,  G06F19/00 ,  G06F19/321 ,  G06F19/324 ,  G06Q10/10 ,  G06Q50/22 ,  G06Q50/24 ,  G16H10/60 ,  Y10S707/915 ,  Y10S707/99933 ,  Y10S707/99942 ,  Y10S707/99943 ,  Y10S707/99944 ,  Y10S707/99945

摘要： A system for collecting, managing and disseminating information relating to medical procedures includes a central computer and a plurality of medical devices each in communication with an injector, a scanner, a hospital system and/or at least one other device. Each medical device receives (I) before a procedure is performed, patient identification information from a user interface, the scanner and/or the hospital system and (II) during and/or after the procedure, injection information from the injector and imaging study information from the scanner. Each medical device has an associated database for storing as a record therein the patient identification information, the injection information and the imaging study information for each procedure performed on each patient. The central computer remotely links to each medical device for accessing, collecting and storing in a related database the records transmitted therefrom and for analyzing the records and creating therefrom at least one related entry based thereon.

摘要翻译： 用于收集，管理和传播与医疗程序有关的信息的系统包括中央计算机和与注射器，扫描器，医院系统和/或至少一个其他装置通信的多个医疗装置。 每个医疗设备在执行手术之前接收（I），在用户接口，扫描器和/或医院系统中的患者识别信息和（II）在过程期间和/或之后，来自注射器的注射信息和成像研究信息 从扫描仪。 每个医疗设备具有相关联的数据库，用于在其中存储用于每个患者执行的每个过程的患者识别信息，注射信息和成像研究信息。 中央计算机远程链接到每个医疗设备，用于访问，收集和存储在相关数据库中从其发送的记录和用于分析记录并根据其创建至少一个相关条目。

公开(公告)号：US07713239B2

公开(公告)日：2010-05-11

申请号：US10821210

申请日：2004-04-08

申请人： Arthur E. Uber, III ,  Alan D. Hirschman ,  David M. Griffiths ,  Frederick W. Trombley ,  David M. Reilly

发明人： Arthur E. Uber, III ,  Alan D. Hirschman ,  David M. Griffiths ,  Frederick W. Trombley ,  David M. Reilly

IPC分类号： A61M37/00

CPC分类号： A61M25/0045 ,  A61J1/2096 ,  A61M5/007 ,  A61M5/1408 ,  A61M5/142 ,  A61M5/1452 ,  A61M5/44 ,  A61M2202/049 ,  A61N5/1001

摘要： A system for injecting a patient, includes a container enclosing a hazardous pharmaceutical; a first pump to deliver a hazardous pharmaceutical to a patient and a fluid path operably connected to the first pump, the container, and the patient. The system further includes a hazardous material containment suitable to confine the hazardous pharmaceutical during connection of the hazardous pharmaceutical container to the fluid path.

摘要翻译： 一种用于注射患者的系统，包括容纳危险药物的容器; 向患者输送危险药物的第一泵和可操作地连接到第一泵，容器和患者的流体路径。 该系统还包括适合于在将危险药物容器连接到流体路径期间限制危险药物的危险材料容纳物。

公开(公告)号：US20090326370A1

公开(公告)日：2009-12-31

申请号：US12534987

申请日：2009-08-04

申请人： Arthur E. Uber, III ,  Edward J. Rhinehart ,  Rosemary Almon-Martin ,  David M. Griffiths ,  Alan D. Hirschman ,  Francis J. Sciulli ,  Walter Grumski ,  Vera Pagano ,  Karen Zelenski

发明人： Arthur E. Uber, III ,  Edward J. Rhinehart ,  Rosemary Almon-Martin ,  David M. Griffiths ,  Alan D. Hirschman ,  Francis J. Sciulli ,  Walter Grumski ,  Vera Pagano ,  Karen Zelenski

IPC分类号： A61B6/00

CPC分类号： A61B8/481 ,  A61B6/481 ,  A61B6/504 ,  A61B8/06 ,  A61M5/007 ,  A61M5/14546 ,  A61M5/1723 ,  A61M2205/581 ,  A61M2205/80 ,  G06F19/00 ,  G06F19/321 ,  G06F19/3468

摘要： A system for producing a contrast-enhanced medical image of a patient includes a source of a contrast or enhancement medium, a pressurizing unit in fluid connection with the source of contrast or enhancement medium, an energy source operable to apply energy to a region of the patient, an imaging unit providing a visual display of an internal view of the patient based upon a signal resulting from the energy applied to the region of the patient, and a control unit. In an embodiment, the signal is affected by a condition of the contrast or enhancement medium in the patient. To control the procedures, the control unit adjusts the condition of the contrast or enhancement medium in the patient based upon the signal. A communication interface preferably enables information between an injector subsystem and an imaging subsystem.

摘要翻译： 用于产生患者的对比度增强的医学图像的系统包括对比度或增强介质的源，与对比度或增强介质源流体连接的加压单元，可操作以将能量施加到所述对比度或增强介质的区域的能量源 患者，成像单元，其基于由施加到患者的区域的能量产生的信号以及控制单元提供患者的内部视图的视觉显示。 在一个实施例中，该信号受到患者中的对比度或增强介质的状况的影响。 为了控制程序，控制单元基于该信号来调整患者的对比度或增强介质的状况。 通信接口优选地实现喷射器子系统和成像子系统之间的信息。

公开(公告)号：US07094216B2

公开(公告)日：2006-08-22

申请号：US09982518

申请日：2001-10-18

申请人： Frederick W. Trombley, III ,  Robert M. Schmidt ,  David M. Reilly ,  Alan D. Hirschman ,  David M. Griffiths ,  Gerald W. Callan ,  Luis A. Pedraza ,  Jennie Kwo ,  Christopher T. Zirps ,  Roderick H. Beaulieu

发明人： Frederick W. Trombley, III ,  Robert M. Schmidt ,  David M. Reilly ,  Alan D. Hirschman ,  David M. Griffiths ,  Gerald W. Callan ,  Luis A. Pedraza ,  Jennie Kwo ,  Christopher T. Zirps ,  Roderick H. Beaulieu

IPC分类号： A61M31/00

CPC分类号： A61M5/007 ,  A61M5/14546 ,  A61M5/16827 ,  A61M31/005 ,  A61M39/22 ,  A61M2005/1403 ,  A61M2205/582 ,  A61M2209/01 ,  Y10T137/7727

摘要： An injector system includes a powered injector, a pressurizing chamber in operative connection with the powered injector, a fluid path in fluid connection with the pressurizing chamber, and a manual control in fluid connection with the fluid path. The manual control includes at least one actuator for controlling the injector through application of force by an operator. The actuator provides tactile feedback of pressure in the fluid path to the operator via a fluid connection with the fluid path. An injection system for use in angiography includes a source of saline, a pump in fluid connection with the source of saline to pressurize the saline, a saline valve in fluid connection via a first port thereof with an outlet of the pump, a first connector in fluid connection with a second port of the saline valve, a source of contrast, a contrast valve in fluid connection with the source of contrast via a first port of the contrast valve, a powered injector in fluid connection with a second port of the contrast valve, a second connector in fluid connection with a third port of the contrast valve, and a pressure isolation mechanism.

摘要翻译： 注射器系统包括动力注射器，与动力注射器可操作地连接的加压室，与加压室流体连接的流体路径，以及与流体路径流体连接的手动控制。 手动控制包括至少一个执行器，用于通过操作者施加力来控制喷射器。 致动器通过与流体路径的流体连接提供到操作者的流体路径中的压力的​​触觉反馈。 用于血管造影术的注射系统包括盐水源，与盐水源流体连接以对盐水加压的泵，经由其第一端口与泵的出口流体连接的盐水阀，第一连接器 与盐水阀的第二端口的流体连接，对比度源，通过对比度阀的第一端口与对比源流体连接的对比度阀，与对比度阀的第二端口流体连接的动力注射器 与对比度阀的第三端口流体连接的第二连接器和压力隔离机构。

公开(公告)号：US06939302B2

公开(公告)日：2005-09-06

申请号：US10034266

申请日：2001-10-19

申请人： David M. Griffiths ,  Arthur E. Uber, III

发明人： David M. Griffiths ,  Arthur E. Uber, III

IPC分类号： A61B8/00 ,  A61M5/00 ,  A61M5/145 ,  A61B8/14

CPC分类号： A61M5/14546 ,  A61B8/481 ,  A61M5/007

摘要： A system for delivery of a medium having ultrasound contrast enhancement agents therein to a patient includes a pressurizing device for pressurizing the medium, a fluid path connecting the pressurizing device to the patient and a concentration sensor in communication with the fluid path. The concentration of the contrast enhancement agents is measured by the concentration sensor during injection of the medium into the patient to assist in controlling the delivery system and/or an imaging procedure.

摘要翻译： 用于将具有超声造影增强剂的介质输送到患者的系统包括用于对介质加压的加压装置，将加压装置连接到患者的流体路径和与流体路径连通的浓度传感器。 通过浓度传感器在将介质注射到患者体内以帮助控制递送系统和/或成像过程时测量对比度增强剂的浓度。

公开(公告)号：US06673033B1

公开(公告)日：2004-01-06

申请号：US09721427

申请日：2000-11-22

申请人： Francis J. Sciulli ,  David M. Griffiths ,  William J. Nolan, Jr. ,  Richard G. Critchlow ,  Salvatore J. Dedola ,  Michael A. Spohn ,  Frank A. Lazzaro ,  Thomas P. Joyce ,  John R. Gardner

发明人： Francis J. Sciulli ,  David M. Griffiths ,  William J. Nolan, Jr. ,  Richard G. Critchlow ,  Salvatore J. Dedola ,  Michael A. Spohn ,  Frank A. Lazzaro ,  Thomas P. Joyce ,  John R. Gardner

IPC分类号： A61M3100

CPC分类号： A61M5/172 ,  A61M5/007 ,  A61M5/1413 ,  A61M5/14546 ,  A61M5/14566 ,  A61M5/16854 ,  A61M2205/702

摘要： An injector for use in injecting a fluid in a medical injection procedure includes a drive mechanism to pressurize the fluid; a sensor to measure a variable that is proportional to fluid pressure (that is, a direct or indirect measurement of fluid pressure); and a pressure monitor (for example, including hardwired circuitry and/or software) in communication with the sensor and the drive mechanism to stop the injection procedure when the sensor measures a value of the variable that corresponds to a pressure hazard limit. Preferably, the pressure monitor further limits power input to the drive mechanism to a power limit once the variable reaches a value that corresponds to a power limiting pressure that is below the pressure hazard limit.

摘要翻译： 用于在医疗注射程序中注射流体的注射器包括用于对流体加压的驱动机构; 用于测量与流体压力成比例的变量的传感器（即，直接或间接测量流体压力）; 以及与传感器和驱动机构通信的压力监视器（例如，包括硬连线电路和/或软件），以在传感器测量与压力危险极限对应的变量的值时停止喷射过程。 优选地，一旦变量达到对应于低于压力危险极限的功率限制压力的值，压力监视器进一步将输入到驱动机构的功率限制在功率极限。