公开(公告)号：US20230346251A1

公开(公告)日：2023-11-02

申请号：US18131126

申请日：2023-04-05

Applicant: Endomagnetics Ltd

Inventor： Quentin John Harmer ,  Tiziano Agostinelli

IPC: A61B5/06 ,  A61B5/00

CPC classification number: A61B5/062 ,  A61B5/7221 ,  A61B5/725 ,  A61B5/7405 ,  A61B5/7435 ,  A61B5/7475 ,  A61B2090/3954

Abstract: In part, the disclosure relates to a method of detecting a marker in a subject in the presence of one or more interfering signals. The method may include detecting a first marker signal; detecting a first interfering signal; comparing one or more characteristics or a metric correlated therewith of the first interfering signal with an interference signal threshold; and generating user feedback based on the comparison and/or movement of a detection probe.

公开(公告)号：US20230277083A1

公开(公告)日：2023-09-07

申请号：US18024448

申请日：2021-09-06

Applicant: ENDOMAGNETICS LTD

Inventor： Quentin John Harmer ,  Tiziano Agostinelli

IPC: A61B5/06 ,  A61B90/00

CPC classification number: A61B5/062 ,  A61B90/39 ,  A61B2090/3954

Abstract: Systems and Methods for Detecting Magnetic Markers for Surgical Guidance Methods and systems for detecting a magnetic marker for guiding a surgeon to a region of interest during a surgical procedure comprising generating a driving magnetic field having a cyclic pattern comprising two or more successive periods of time, the driving magnetic field having a substantially constant, non-zero amplitude during each of the successive periods of time, and the amplitude of the driving magnetic field during at least one of the periods of time being different from the amplitude of the driving magnetic field during at least one other of the periods of time; detecting a response magnetic field; selecting at least one signal from a plurality of sensed signals, each of which corresponds to the response magnetic field detected during a respective one of the successive periods of time of each cycle; determining a detection signal corresponding to the magnetic marker using the at least one selected signal; and generating an output signal (e.g. an audio or display signal) based on a strength of the detection signal.

公开(公告)号：US11660160B2

公开(公告)日：2023-05-30

申请号：US16256404

申请日：2019-01-24

Applicant: ENDOMAGNETICS LTD

Inventor： Tiziano Agostinelli ,  Kevin Lorimer ,  Quentin John Harmer

IPC: A61B5/00 ,  A61B90/00 ,  A61B5/06 ,  A61B34/20 ,  G01D5/20 ,  A61B17/00

CPC classification number: A61B90/39 ,  A61B5/062 ,  A61B5/064 ,  A61B34/20 ,  G01D5/20 ,  A61B2017/00867 ,  A61B2017/00876 ,  A61B2034/2051 ,  A61B2090/397 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3954 ,  A61B2090/3958 ,  A61B2090/3966 ,  A61B2090/3987 ,  A61B2505/05 ,  A61B2562/0223

Abstract: A detection system and method uses an implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ). The marker is deployed to mark a tissue site in the body for subsequent surgery, and the magnetic detection system includes a handheld probe to excite the marker below the switching field for bistable switching of the marker causing a harmonic response to be generated in a sub-bistable mode that allows the marker to be detected and localised. The marker implanted may also be shorter than the critical length required to initiate bistable switching of the LBJ material.

公开(公告)号：US20190223975A1

公开(公告)日：2019-07-25

申请号：US16256404

申请日：2019-01-24

Applicant: ENDOMAGNETICS LTD

Inventor： Tiziano Agostinelli ,  Kevin Lorimer ,  Quentin John Harmer

IPC: A61B90/00 ,  A61B5/06 ,  G01D5/20

Abstract: A detection system and method uses an implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ). The marker is deployed to mark a tissue site in the body for subsequent surgery, and the magnetic detection system includes a handheld probe to excite the marker below the switching field for bistable switching of the marker causing a harmonic response to be generated in a sub-bistable mode that allows the marker to be detected and localised. The marker implanted may also be shorter than the critical length required to initiate bistable switching of the LBJ material.

公开(公告)号：US09808539B2

公开(公告)日：2017-11-07

申请号：US14202178

申请日：2014-03-10

Applicant: Endomagnetics Ltd.

Inventor： Andrew P. Shawcross ,  John Gonzalez-Carvajal ,  Marc Brown ,  Rob Turner

IPC: A61B5/055 ,  A61K49/18 ,  A61K41/00 ,  A61N2/00

CPC classification number: A61K49/1806 ,  A61K41/0052 ,  A61K49/1863 ,  A61N2/002

Abstract: Provided are compositions for rapid detection of lymph nodes. The compositions include magnetic particles, such as iron oxide, and a solute present in an amount that results in a hypoosomotic solution. Methods for detecting lymph nodes also are provided.

公开(公告)号：US20160124057A1

公开(公告)日：2016-05-05

申请号：US14992682

申请日：2016-01-11

Applicant: ENDOMAGNETICS LTD

Inventor： Simon Richard Hattersley

IPC: G01R33/12 ,  G01N27/72

CPC classification number: G01R33/1276 ,  A61B5/05 ,  G01N27/72 ,  G01N27/745 ,  G01R33/0213 ,  G01R33/10

Abstract: A probe for detecting magnetic particles. In one embodiment, the probe includes: a cylindrical probe core having a first end and a second end, the cylindrical probe core defining two channels for containing coils of wire, one of the channels being adjacent the first end of the cylindrical probe core; two sense coils, one each of the sense coils being located in a respective one of the channels; and two drive coils, one each of the drive coils being co-located with the respective sense coil in a respective one of the channels.

Abstract translation: 用于检测磁性颗粒的探头。 在一个实施例中，探针包括：具有第一端和第二端的圆柱形探针芯，所述圆柱形探针芯限定用于容纳线圈的两个通道，所述通道中的一个与所述圆柱形探针芯的第一端相邻; 两个感测线圈，每个感测线圈位于相应的一个通道中; 和两个驱动线圈，每个驱动线圈与相应的一个通道中的相应感测线圈共同定位。