公开(公告)号：US10249400B2

公开(公告)日：2019-04-02

申请号：US15805647

申请日：2017-11-07

Applicant: Ion Beam Applications S.A.

Inventor： Michel Abs ,  Willem Kleeven ,  Jarno Van De Walle ,  Jérémy Brison ,  Denis Deschodt

IPC: G21K5/04 ,  H05H7/18 ,  H05H13/10 ,  G21K1/093

Abstract: An electron accelerator comprising a resonant cavity, an electron source, an RF system, and at least one magnet unit is provided. The resonant cavity further comprises a hollow closed conductor and the electron source is configured to radially inject a beam of electrons into the cavity. The RF system is configured to generate an electric field to accelerate the electrons along radial trajectories. The at least one magnet unit further comprises a deflecting magnet configured to generate a magnetic field that deflects an electron beam emerging out of the resonant cavity along a first radial trajectory and redirects the electron beam into the resonant cavity along a second radial trajectory. The resonant cavity further comprises a first half shell, a second half shell, and a central ring element.

公开(公告)号：US10195461B2

公开(公告)日：2019-02-05

申请号：US15835980

申请日：2017-12-08

Applicant: Ion Beam Applications S.A.

Inventor： Carolina Fuentes

IPC: A61N5/00 ,  A61N5/10 ,  A61B3/00 ,  A61F9/007 ,  A61B3/14 ,  A61B90/00

Abstract: A particle therapy apparatus for irradiating a diseased part of a patient's eye with a charged particle beam comprises a particle accelerator to generate the particle beam, a movable irradiation nozzle adapted to direct the particle beam towards the patient's eye according to different beam directions, and a patient support adapted to receive and hold the patient in a treatment position. The apparatus further comprises a pencil beam scanning subsystem configured to scan the particle beam over the diseased part of the patient's eye, a movable marker arranged in such a way that it is visible by the patient while he is in the treatment position and a controller configured to move said marker to a pre-determined and patient-specific position before starting an irradiation of the eye with the particle beam.

公开(公告)号：US10070510B2

公开(公告)日：2018-09-04

申请号：US15725350

申请日：2017-10-05

Applicant: Ion Beam Applications S.A.

Inventor： Gabriel Krier ,  Sèbastien Henrotin ,  Yves Claereboudt

IPC: G21G5/00 ,  H05H13/00 ,  H05H13/02 ,  H05H7/02 ,  H05H7/04 ,  H05H7/00 ,  A61N5/10

Abstract: The embodiments of the present disclosure relate to a method and system for controlling the extraction of ion beam pulses produced by a synchrocyclotron. The synchrocyclotron comprises electrodes configured to be placed in a magnetic field. An alternating voltage is applied between the electrodes, and the frequency of the alternating voltage is modulated in a cyclic manner. In other embodiments, the method further comprises the steps of starting an acceleration cycle of the synchrocyclotron, generating a reference signal when the modulated frequency reaches a predefined value, communicating the time, at which the reference signal is generated, to the beam control elements, assessing one or more status parameters of the one or more beam control elements, and cancelling or proceeding with the extraction of the beam pulse depending on the results of the assessment.

公开(公告)号：US10064264B2

公开(公告)日：2018-08-28

申请号：US15594525

申请日：2017-05-12

Applicant: Ion Beam Applications, S.A.

Inventor： Michel Abs ,  Szymon Zaremba

IPC: H01F7/02 ,  H05H7/10 ,  H05H7/04 ,  H05H13/00 ,  H05H7/00 ,  H05H13/08 ,  H01F3/10 ,  H01F7/20

CPC classification number: H05H7/10 ,  H01F3/10 ,  H01F7/02 ,  H01F7/20 ,  H05H7/001 ,  H05H7/04 ,  H05H13/005 ,  H05H13/08 ,  H05H2007/002 ,  H05H2007/043

Abstract: The present disclosure relates to a magnet pole for an isochronous sector-focused cyclotron having hill and valley sectors alternatively distributed around a central axis, Z, each hill sector having an upper surface bounded by four edges: an upper peripheral edge, an upper central edge, a first and a second upper lateral edges. The upper surface of at least one hill sector may further include: a recess extending over a length between a proximal end and a distal end along a longitudinal axis intersecting the upper peripheral edge and the upper central edge. The recess may be separate from the first and second upper lateral edges over at least 80% of its length, and a pole insert having a geometry fitting in the recess may be positioned in, and reversibly coupled to the recess.

公开(公告)号：US09961757B2

公开(公告)日：2018-05-01

申请号：US15594527

申请日：2017-05-12

Applicant: Ion Beam Applications, S.A.

Inventor： Willem Kleeven ,  Michel Abs

IPC: H05H13/00 ,  H05H7/04 ,  H05H7/10

CPC classification number: H05H7/10 ,  H01F3/10 ,  H01F7/02 ,  H01F7/20 ,  H05H7/001 ,  H05H7/04 ,  H05H13/005 ,  H05H13/08 ,  H05H2007/002 ,  H05H2007/043

Abstract: The present disclosure relates to a magnet pole for an isochronous sector-focused cyclotron having hill and valley sectors alternatively distributed around a central axis, Z, each hill sector having an upper surface bounded by four edges: an upper peripheral edge, an upper central edge, a first and a second upper lateral edges. The upper peripheral edge of a hill sector may be an arc of circle whose center is offset with respect to the central axis, and whose radius, Rh, is not more than 85% of a distance, Lh, from the central axis to a midpoint of the upper peripheral edge. Furthermore, the midpoint may be equidistant to the first and second upper distal ends.

公开(公告)号：US20180099155A1

公开(公告)日：2018-04-12

申请号：US15727292

申请日：2017-10-06

Applicant: Ion Beam Applications S.A.

Inventor： Damien PRIEELS ,  Erik VAN DER KRAAIJ ,  Sébastien HENROTIN ,  Caterina BRUSASCO

IPC: A61N5/10 ,  G01R33/48 ,  G01R33/483 ,  G01R33/56 ,  A61B5/055 ,  A61B5/00

CPC classification number: A61N5/1039 ,  A61B5/055 ,  A61B5/743 ,  A61N5/1049 ,  A61N5/1065 ,  A61N2005/1055 ,  A61N2005/1074 ,  A61N2005/1085 ,  A61N2005/1087 ,  G01R33/4808 ,  G01R33/4833 ,  G01R33/5608

Abstract: The present disclosure relates to a method and a medical apparatus for visualizing on magnetic resonance (MR) images a hadron beam path traversing an organic body. The present method may utilize artefacts in MR image acquisition provoked by the changes in properties of excitable atoms when irradiated by a hadron beam. By synchronizing the hadron pulses with different steps of MR data acquisition, it is possible to identify such artefacts and determine, based on their positions, the hadron beam path and the corresponding position of the Bragg peak.

公开(公告)号：US20180098745A1

公开(公告)日：2018-04-12

申请号：US15567879

申请日：2016-04-22

Applicant: Ion Beam Applications S.A.

Inventor： Simon MARCELIS ,  Yves CLAEREBOUDT ,  Thierry MERTENS ,  Frédéric DESSY

IPC: A61B6/00 ,  A61B6/12 ,  A61N5/10

CPC classification number: A61B6/584 ,  A61B6/12 ,  A61B6/4014 ,  A61N5/1043 ,  A61N5/1044 ,  A61N5/1071 ,  A61N5/1075 ,  A61N2005/105 ,  A61N2005/1061 ,  A61N2005/1076 ,  A61N2005/1087

Abstract: A phantom and method for quality assurance of a particle therapy apparatus used in the intensity modulated particle therapy (IMPT) mode is provided. The phantom comprises a frame structure having a first face and a second face that is parallel to the first face. The phantom further comprises one or more wedges, and a first and second block of material each having a first block face and a second block face parallel thereto. In addition, the phantom further includes an absolute dosimeter arranged at the first block face. A plurality of beads of high density material is located in the first or second block, and a 2D detector is arranged at the second face of the frame structure.

公开(公告)号：US09878181B2

公开(公告)日：2018-01-30

申请号：US14834059

申请日：2015-08-24

Applicant: Ion Beam Applications S.A. ,  Instituto Nazionale di Fisica Nucleare ,  Internet-Simulation Evaluation Envision SRL

Inventor： Germano Russo ,  Andrea Attili ,  Flavio Pietro Marchetto ,  Damien Bertrand ,  Faiza Bourhaleb

IPC: A61N5/10

CPC classification number: A61N5/1075 ,  A61N5/1031 ,  A61N5/1043 ,  A61N2005/1076 ,  A61N2005/1087

Abstract: The method of the invention comprises the steps of: providing a reference ion beamlet; determining in a phantom (60) a distribution of a linearly-superposable quantity representing a linearly-superposable effect induced by said reference ion beamlet; approximating an ion beam (10) as a weighted superposition of ion beamlets (15), said weighted superposition comprising weight coefficients, at least one ion beamlet (15) being obtained by applying a roto-translation operation to said reference ion beamlet; determining a roto-translated distribution of a linearly-superposable quantity by roto-translating said distribution of a linearly-superposable quantity with said roto-translation operation; determining said physical and/or radiobiological quantities by performing a weighted superposition comprising said weight coefficients, and said roto-translated distribution of a linearly-superposable quantity.

公开(公告)号：US20180009711A1

公开(公告)日：2018-01-11

申请号：US15642007

申请日：2017-07-05

Applicant: Ion Beam Applications S.A.

Inventor： Frédéric Stichelbaut ,  Julie Piérard ,  Laura Kupers

IPC: C04B14/28 ,  C04B7/02 ,  C04B7/32 ,  C04B111/00

CPC classification number: C04B14/28 ,  C04B7/02 ,  C04B7/32 ,  C04B28/02 ,  C04B28/06 ,  C04B2111/00215 ,  C04B2111/00258 ,  C04B2111/00612 ,  C04B2111/00862 ,  C04B2111/802 ,  G21F1/04

Abstract: The present invention relates to a low-activation concrete comprising high-purity limestone aggregate and white cement, or high-purity limestone aggregate and aluminous cement. The low-activation concrete reduces the content of Europium, Cobalt and Cesium, as well as the content of elements such as Aluminium, Sodium, and Magnesium, when compared to standard concrete compositions and compositions for low-activation concrete already known in the art. The use of the low-activation concrete for forming an interior wall of a particle accelerator vault is provided as well.

公开(公告)号：US20160172067A1

公开(公告)日：2016-06-16

申请号：US14972014

申请日：2015-12-16

Applicant: Ion Beam Applications S.A.

Inventor： Yves CLAEREBOUDT ,  Alexandre DEBATTY ,  Nicolas GERARD

IPC: G21K1/10

CPC classification number: G21K1/00 ,  A61N5/1077 ,  A61N2005/1087 ,  A61N2005/1095 ,  G21K1/10 ,  H05H7/12 ,  H05H2007/125 ,  H05H2277/11

Abstract: Disclosed embodiments include an energy degrader for attenuating the energy of a charged particle beam. The energy degrader may include a first energy attenuation member presenting a annular beam entry face and a continuous helical beam exit face, a second energy attenuation member presenting a continuous helical beam entry face and an annular beam exit face. The first and second helical surfaces may face each other. The energy degrader may also include a drive assembly configured for rotating the first and the second energy attenuation members around respectively a first axis and a second axis which are parallel to each other. The degrader may have a small moment of inertia, allowing more accurate and faster variation of the beam energy.

Abstract translation: 公开的实施例包括用于衰减带电粒子束的能量的能量降解器。 能量降解器可以包括呈现环形束入射面和连续的螺旋射束出射面的第一能量衰减构件，呈现连续的螺旋梁进入面和环形射束出射面的第二能量衰减构件。 第一和第二螺旋表面可以彼此面对。 能量降解器还可以包括驱动组件，其被配置为分别围绕彼此平行的第一轴和第二轴旋转第一和第二能量衰减构件。 降解器可能具有小的惯性矩，从而允许更准确和更快地改变光束能量。