公开(公告)号：US20210137956A1

公开(公告)日：2021-05-13

申请号：US16905750

申请日：2020-06-18

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Geoffrey A. von Maltzahn ,  Yvonne J. Yamanaka

IPC: A61K31/702 ,  A61K45/06 ,  A61K31/715 ,  A61K31/733 ,  A61K31/716 ,  A61P1/02 ,  A61P15/02 ,  A61P31/04 ,  A61P11/02 ,  A61K8/60 ,  A61K8/73 ,  A61K8/99 ,  A61K9/00 ,  A61K35/741 ,  A61K35/742 ,  A61K35/744 ,  A61K35/745 ,  A61K35/747 ,  A61Q11/00

Abstract: Compositions comprising glycan preparations suitable for local administration to non-gut sites containing mucosal tissue, e.g., oral cavity, nasal cavity and vagina are provided. Further provided are methods of using said glycan preparations.

公开(公告)号：US10894057B2

公开(公告)日：2021-01-19

申请号：US16140091

申请日：2018-09-24

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Geoffrey A. von Maltzahn ,  Yvonne J. Yamanaka ,  Jared Silverman ,  John Miles Milwid ,  Jacob Rosenblum Rubens ,  John M. Geremia

IPC: A61K31/702 ,  A61K35/741 ,  A23L33/135 ,  A61P35/04 ,  A23L33/125 ,  A61P1/00 ,  A61K31/716 ,  A61K31/733 ,  A61P35/00 ,  A61K45/06 ,  A61P3/02 ,  A61P43/00

Abstract: Preparations of glycan therapeutics, pharmaceutical compositions, dietary supplements and medical foods thereof are provided, and methods of using said gycan therapeutics, e.g. in cancer therapy.

公开(公告)号：US10881676B2

公开(公告)日：2021-01-05

申请号：US16396067

申请日：2019-04-26

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Geoffrey A. von Maltzahn ,  Jared Silverman ,  Yvonne J. Yamanaka ,  John Miles Milwid ,  John M. Geremia

IPC: A61K31/702 ,  A61K35/741 ,  A61K31/7016 ,  A61K31/7004 ,  A23P10/00 ,  A23L33/10 ,  A61P1/00 ,  A61K31/733 ,  A61K31/716 ,  A61K45/06 ,  A61K31/09 ,  A61K31/11 ,  A61K31/12 ,  A61K31/165 ,  A61K31/34 ,  A61K31/353 ,  A61K31/365 ,  A61K31/366 ,  A61K31/7034 ,  A61K31/7048 ,  A61K31/706 ,  A61K31/715 ,  A61K35/00

Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said gycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.

公开(公告)号：US20180235987A1

公开(公告)日：2018-08-23

申请号：US15754850

申请日：2016-08-25

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Geoffrey A. von Maltzahn ,  Yvonne J. Yamanaka

IPC: A61K31/702 ,  A61K9/00 ,  A61K31/715 ,  A61Q11/00 ,  A61K8/60 ,  A61K8/73 ,  A61K45/06 ,  A61K35/741 ,  A61K35/742 ,  A61K35/744 ,  A61K35/745 ,  A61K35/747 ,  A61K8/99 ,  A61P1/02 ,  A61P11/02 ,  A61P15/02 ,  A61P31/04

CPC classification number: A61K31/702 ,  A61K8/60 ,  A61K8/73 ,  A61K8/99 ,  A61K9/0034 ,  A61K9/0043 ,  A61K9/006 ,  A61K31/715 ,  A61K31/716 ,  A61K31/733 ,  A61K35/741 ,  A61K35/742 ,  A61K35/744 ,  A61K35/745 ,  A61K35/747 ,  A61K45/06 ,  A61K2035/115 ,  A61K2800/5922 ,  A61K2800/594 ,  A61K2800/87 ,  A61K2800/884 ,  A61K2800/92 ,  A61P1/02 ,  A61P11/02 ,  A61P15/02 ,  A61P31/04 ,  A61Q11/00 ,  Y02A50/473

Abstract: Compositions comprising glycan therapeutics, optionally comprising one or more oligo- or polysaccharides, probiotics, prebiotics and other agents are provided. Further, methods of generating said glycan therapeutics using polymeric catalysts are described. Also provided are methods of using said gycan therapeutics, e.g. for the modulation of vaginal microbiota.

公开(公告)号：US09492473B2

公开(公告)日：2016-11-15

申请号：US15017396

申请日：2016-02-05

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Geoffrey A. von Maltzahn ,  Jared Silverman ,  Yvonne J. Yamanaka ,  John Miles Milwid ,  John M. Geremia

IPC: A61K31/716 ,  A61K31/715 ,  A61K31/7048 ,  A61K31/12 ,  A61K31/7034 ,  A61K31/353 ,  A61K31/09 ,  A61K31/34 ,  A61K31/365 ,  A61K31/11 ,  A61K31/366 ,  A61K31/706 ,  A61K31/165 ,  A61K35/00

CPC classification number: A61K31/716 ,  A61K31/09 ,  A61K31/11 ,  A61K31/12 ,  A61K31/165 ,  A61K31/34 ,  A61K31/353 ,  A61K31/365 ,  A61K31/366 ,  A61K31/7034 ,  A61K31/7048 ,  A61K31/706 ,  A61K31/715 ,  A61K2035/115

Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.

Abstract translation: 提供了聚糖治疗剂，其药物组合物和医药食品，任选地包含微量营养素，多酚，益生元，益生菌或其它药剂的制备方法及其制备方法。 还提供了使用所述聚糖治疗剂的方法，例如， 用于调节人类胃肠道微生物群并治疗生殖器发育不良。