公开(公告)号：US09242090B2

公开(公告)日：2016-01-26

申请号：US14326183

申请日：2014-07-08

Applicant: MRI Interventions, Inc. ,  Greatbatch Ltd.

Inventor： Ergin Atalar ,  Robert Susil ,  Albert Lardo ,  Henry R. Halperin

IPC: A61N1/00 ,  A61N1/08 ,  A61N1/05 ,  A61B5/042 ,  A61B18/14 ,  A61N1/37

CPC classification number: A61N1/08 ,  A61B5/042 ,  A61B18/14 ,  A61N1/05 ,  A61N1/056 ,  A61N1/086 ,  A61N1/3718

Abstract: Herein is disclosed a probe, including a first electrode disposed at least partially on the probe surface, a second electrode disposed at least partially on the probe surface, a first conductor electrically coupled to the first electrode, a second conductor electrically coupled to the second electrode, and a reactive element electrically coupling the first conductor and the second conductor.

Abstract translation: 本文公开了一种探针，包括至少部分地设置在探针表面上的第一电极，至少部分地设置在探针表面上的第二电极，电耦合到第一电极的第一导体，电耦合到第二电极的第二导体 以及电连接第一导体和第二导体的电抗元件。

公开(公告)号：US20150223905A1

公开(公告)日：2015-08-13

申请号：US14693456

申请日：2015-04-22

Applicant: MRI Interventions, Inc.

Inventor： Parag V. Karmarkar ,  Kimble Jenkins

IPC: A61B19/00 ,  A61N1/05 ,  A61B5/00 ,  A61B5/0476 ,  A61B5/055

CPC classification number: A61B90/11 ,  A61B5/0476 ,  A61B5/055 ,  A61B5/6847 ,  A61B5/6864 ,  A61B5/6865 ,  A61B5/7435 ,  A61B34/10 ,  A61B34/20 ,  A61B90/14 ,  A61B2017/00039 ,  A61B2034/107 ,  A61B2034/2051 ,  A61B2090/374 ,  A61B2090/3954 ,  A61M39/08 ,  A61N1/0529 ,  A61N1/0534 ,  A61N1/0539 ,  A61N1/08 ,  A61N1/086 ,  A61N1/3718 ,  A61N1/372 ,  A61N2001/086 ,  G01R33/285 ,  G01R33/286 ,  G01R33/287 ,  G01R33/288 ,  G01R33/34084 ,  G01R33/4808

Abstract: MRI compatible localization and/or guidance systems for facilitating placement of an interventional therapy and/or device in vivo include: (a) a mount adapted for fixation to a patient; (b) a targeting cannula with a lumen configured to attach to the mount so as to be able to controllably translate in at least three dimensions; and (c) an elongate probe configured to snugly slidably advance and retract in the targeting cannula lumen, the elongate probe comprising at least one of a stimulation or recording electrode. In operation, the targeting cannula can be aligned with a first trajectory and positionally adjusted to provide a desired internal access path to a target location with a corresponding trajectory for the elongate probe. Automated systems for determining an MR scan plane associated with a trajectory and for determining mount adjustments are also described.

Abstract translation: 用于促进介入治疗和/或装置体内放置的MRI兼容的定位和/或引导系统包括：（a）适于固定于患者的安装座; （b）具有被配置为附接到所述安装件以便能够可控地平移至少三个维度的内腔的靶向插管; 以及（c）细长探针，其被配置为在所述靶向插管腔中紧密地滑动地前进和后退，所述细长探针包括刺激或记录电极中的至少一个。 在操作中，瞄准套管可以与第一轨迹对准，并且被位置调节以便为具有针对细长探针的对应轨迹的目标位置提供期望的内部通路。 还描述了用于确定与轨迹相关联并用于确定安装调整的MR扫描平面的自动化系统。

公开(公告)号：US20150011869A1

公开(公告)日：2015-01-08

申请号：US14290051

申请日：2014-05-29

Applicant: MRI Interventions, Inc.

Inventor： Peter Piferi ,  Kamal Vij ,  Scott Arnold

IPC: A61B5/055 ,  A61B19/00 ,  A61B6/04

CPC classification number: A61B5/0555 ,  A61B6/0407

Abstract: Scanner Systems with table stabilizers for stabilizing patient support structures during a surgery include a stabilizer block that can cooperate with the gantry to structurally support a head end portion of the table to prevent undesired movement of the table under an end load.

Abstract translation: 具有用于在手术期间稳定患者支撑结构的台面稳定器的扫描仪系统包括可与机架配合的稳定器块，以结构地支撑工作台的头端部分，以防止工作台在端部负载下的不期望的移动。

公开(公告)号：US08886288B2

公开(公告)日：2014-11-11

申请号：US13738621

申请日：2013-01-10

Applicant: MRI Interventions, Inc.

Inventor： Kimble L. Jenkins ,  Peter Piferi ,  Kamal Vij ,  Daniele Ghidoli ,  Jesse Flores

IPC: A61B5/05 ,  A61B5/06 ,  A61B5/055 ,  A61B5/00 ,  A61M25/01 ,  G01R33/28 ,  A61B5/042 ,  A61B18/18 ,  A61B5/053 ,  A61B18/02 ,  A61M5/00 ,  A61B19/00 ,  A61M29/00 ,  A61M25/00 ,  A61M25/06 ,  A61M25/09

CPC classification number: A61B5/062 ,  A61B5/0044 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/053 ,  A61B5/055 ,  A61B5/065 ,  A61B5/415 ,  A61B5/418 ,  A61B18/02 ,  A61B18/18 ,  A61B34/10 ,  A61B34/20 ,  A61B2090/365 ,  A61B2090/374 ,  A61B2090/3954 ,  A61M5/00 ,  A61M25/01 ,  A61M25/0127 ,  A61M29/00 ,  A61M2025/0089 ,  A61M2025/0166 ,  A61M2025/0681 ,  A61M2025/09175 ,  G01R33/286 ,  G01R33/287

Abstract: An MRI-compatible catheter includes an elongated flexible shaft having opposite distal and proximal end portions. A handle is attached to the proximal end portion and includes an actuator in communication with the shaft distal end portion that is configured to articulate the shaft distal end portion. The distal end portion of the shaft may include an ablation tip and includes at least one RF tracking coil positioned adjacent the ablation tip that is electrically connected to an MRI scanner. The at least one RF tracking coil is electrically connected to a circuit that reduces coupling when the at least one RF tracking coil is exposed to an MRI environment. Each RF tracking coil is a 1-10 turn solenoid coil, and has a length along the longitudinal direction of the catheter of between about 0.25 mm and about 4 mm.

Abstract translation: MRI兼容导管包括具有相对的远端和近端部分的细长柔性轴。 手柄附接到基端部，并且包括与轴远端部连通的致动器，该致动器构造成铰接轴远端部。 轴的远端部分可以包括消融尖端，并且包括邻近消融尖端定位的至少一个RF跟踪线圈，其被电连接到MRI扫描器。 当至少一个RF跟踪线圈暴露于MRI环境时，至少一个RF跟踪线圈电连接到减少耦合的电路。 每个RF跟踪线圈是1-10圈电磁线圈，并且沿着导管的纵向方向具有在约0.25mm和约4mm之间的长度。

公开(公告)号：US20140257086A1

公开(公告)日：2014-09-11

申请号：US13789868

申请日：2013-03-08

Applicant: MRI INTERVENTIONS, INC.

Inventor： Daniele Ghidoli ,  Kamal Vij

IPC: A61B5/055

CPC classification number: A61B5/055 ,  A61M25/0015 ,  G01R33/287 ,  G01R33/34084 ,  Y10T29/49016

Abstract: Intrabody MRI-compatible medical devices with a rigid stylet body with opposing distal and proximal ends with a wall enclosing at least one cavity extending therebetween. The stylet body has first and second laterally spaced apart and opposing external longitudinally extending recessed surfaces and at least one pair of transversely spaced apart apertures extending through the wall and at least one conductor having a length that extends through the cavity then exits the cavity to define at least one external loop extending between the distal end of the stylet body and the pair of transversely spaced apart apertures. First and second legs of each loop snugly abut a respective first and second recessed surface of the stylet body to thereby cooperate with the stylet body to define a substantially cylindrical shape. The at least one conductor with the at least one loop is configured to act as an MRI antenna.

Abstract translation: 具有刚性探针本体的体内MRI兼容的医疗装置，其具有相对的远端和近端，其中包围至少一个在其间延伸的腔的壁。 探针体具有第一和第二横向间隔开并且相对的外部纵向延伸的凹面和延伸穿过该壁的至少一对横向间隔开的孔，并且具有延伸穿过空腔的长度的至少一个导体然后离开空腔以限定 至少一个在探针体主体的远端和一对横向间隔开的孔之间延伸的外环。 每个环的第一和第二腿紧密地邻接探针体的相应的第一和第二凹入表面，从而与探针体配合以限定基本上圆柱形的形状。 具有至少一个环的至少一个导体被配置为用作MRI天线。

公开(公告)号：US08688226B2

公开(公告)日：2014-04-01

申请号：US13872726

申请日：2013-04-29

Applicant: Boston Scientific Neuromodulation Corporation ,  MRI Interventions, Inc.

Inventor： Ergin Atalar ,  Justin Allen ,  Paul Bottomley ,  William Edelstein ,  Parag V. Karmarkar

IPC: A61N1/00

CPC classification number: A61N1/06 ,  A61N1/056 ,  A61N1/086

Abstract: Some embodiments are directed to MRI/RF compatible medical interventional devices. A plurality of spaced apart high impedance circuit segments are configured to have a high impedance at a high range of radiofrequencies and a low impedance at a low range of frequencies. The high impedance circuit segments may comprise co-wound coiled inductors and can reduce, block or inhibit RJ-transmission along the lead system (20) during exposure to RF associated with a high-Held magnet MRI systems, while permuting passage of low frequency physiologic signals, treatments and/or stimuli. The devices can include at least one electrode.

Abstract translation: 一些实施例涉及MRI / RF兼容医疗介入装置。 多个间隔开的高阻抗电路段被配置为在高频范围内具有高阻抗，并且在低频率范围内具有低阻抗。 高阻抗电路段可以包括共绕线圈电感器，并且可以在暴露于与高磁铁磁共振系统相关联的RF期间沿着引导系统（20）减少，阻止或抑制RJ-传输，同时置换低频生理 信号，治疗和/或刺激。 该装置可以包括至少一个电极。

公开(公告)号：US20140046167A1

公开(公告)日：2014-02-13

申请号：US13772822

申请日：2013-02-21

Applicant: MRI INTERVENTIONS, INC.

Inventor： Kamal Vij ,  Peter Piferi ,  Richard James Kail

IPC: A61B5/00 ,  A61B5/055

CPC classification number: A61B5/7475 ,  A61B5/0046 ,  A61B5/055

Abstract: Fiber optic systems with an MR compatible mouse in an MR scanner room that connects to a fiber optic computer mouse interface that is attached to a fiber optic cable that connects to a USB port of a computer in the MR control room to allow the mouse in the MR scanner room to move a cursor on a monitor in communication with the computer in the control room of an MRI suite during an MRI guided surgical procedure. The fiber optic cable(s) can be routed though a conventional RF wall waveguide and avoids the need for additional holes in the penetration panel for connectors. The fiber optic systems can also include up converters and down converters for providing fiber optic video signals from cameras in the MR scanner room to display video signal on the monitor.

Abstract translation: 在MR扫描仪室中具有MR兼容鼠标的光纤系统，其连接到光纤计算机鼠标接口，该光纤连接到连​​接到MR控制室中的计算机的USB端口的光纤电缆，以允许鼠标在 MR扫描仪室在MRI指导手术过程中将光标移动到与MRI套件的控制室中的计算机通信的监视器上。 光纤电缆可以通过常规RF壁波导路由，并避免在用于连接器的穿透面板中需要额外的孔。 光纤系统还可以包括上变频器和下变频器，用于从MR扫描器室中的相机提供光纤视频信号，以在监视器上显示视频信号。

公开(公告)号：US20130325012A1

公开(公告)日：2013-12-05

申请号：US13788647

申请日：2013-03-07

Applicant: MRI INTERVENTIONS, INC.

Inventor： Peter Piferi ,  Daniele Ghidoli

IPC: A61B17/16

CPC classification number: A61B17/16 ,  A61B17/1624 ,  B23B45/06

Abstract: A surgical, manually operated, hand-held MRI-compatible drill for drilling though target bone of a patient includes: a housing; a ring gear held in the housing; a hand crank attached to ring gear and the housing; a pinion gear held in the housing in cooperating alignment with the ring gear; an elongate shaft attached to the pinion on one end portion and to a chuck support on an opposing end portion; a chuck attached to the chuck support held; and jaws attached to the chuck support and residing in the chuck adapted to hold a drill bit. The drill is light-weight. The components can all be polymeric.

Abstract translation: 一种外科手动操作的手持式MRI兼容钻头，用于穿过患者的目标骨骼，包括：壳体; 保持在壳体中的齿圈; 连接到齿圈和壳体的手动曲柄; 保持在壳体中的与齿圈配合对准的小齿轮; 在一个端部附接到小齿轮的细长轴和在相对的端部上的卡盘支撑件; 夹持在卡盘支架上的卡盘; 以及附接到卡盘支撑件并且驻留在适于保持钻头的卡盘中的卡爪。 钻头重量轻。 组分都可以是聚合物。

公开(公告)号：US20200147299A1

公开(公告)日：2020-05-14

申请号：US16740583

申请日：2020-01-13

Applicant: MRI Interventions, Inc.

Inventor： Peter Piferi

IPC: A61M5/158 ,  A61B90/11 ,  A61M25/01 ,  A61M25/00 ,  A61B5/055 ,  A61B5/00

Abstract: A cannula for transferring a substance to and/or from a patient includes a tubular support sleeve and a transfer tube. The support sleeve includes a rigid tubular member defining a lumen extending from a proximal end to a distal end of the tubular member. The transfer tube is positioned in the lumen and extends beyond each of the proximal end and the distal end of the tubular member. The tubular member includes a rigid, MRI-compatible material.

公开(公告)号：US10376327B2

公开(公告)日：2019-08-13

申请号：US15067615

申请日：2016-03-11

Applicant: MRI Interventions, Inc.

Inventor： Kimble Jenkins ,  Peter Piferi ,  Philip Bradley Hotte ,  Pavel Farberov ,  Timothy Neil Orr ,  Paul Arthur Geiger ,  David John Sayler

IPC: A61B5/00 ,  A61B34/00 ,  G01R33/28 ,  G01R33/3415 ,  A61B90/96 ,  A61B90/11 ,  A61B34/10 ,  A61B90/00 ,  A61B5/055 ,  A61B17/00 ,  A61B17/34 ,  G01R33/54 ,  A61B90/10 ,  A61B90/14

Abstract: Circuits and computer program products onboard and/or adapted to communicate with an scanner that electronically recognize predefined physical characteristics of the at least one tool to automatically segment image data provided by the scanner whereby the at least one tool constitutes a point of interface with the system. The circuits and computer program products are configured to provide a User Interface that defines workflow progression for an image guided surgical procedure and allows a user to select steps in the workflow, and generate multi-dimensional visualizations using the predefined data of the at least one tool and data from images of the patient in substantially real time during the surgical procedure.