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公开(公告)号：US08996137B2
公开(公告)日：2015-03-31
申请号：US14256915
申请日：2014-04-18
Applicant: Oculeve, Inc.
Inventor： Douglas Michael Ackermann , James Donald Loudin , John Wardle , Jarren Armond Baldwin , Daniel N. Hamilton , Janusz Kuzma , Christopher William Stivers
CPC classification number: A61N1/0546 , A61F7/12 , A61H1/00 , A61H9/0071 , A61H21/00 , A61H23/02 , A61H23/0218 , A61H23/0245 , A61H23/0263 , A61H2201/0153 , A61H2201/0173 , A61H2201/0207 , A61H2201/0214 , A61H2201/025 , A61H2201/10 , A61H2201/165 , A61H2201/5002 , A61H2201/5005 , A61H2201/5015 , A61H2201/5035 , A61H2201/5038 , A61H2201/5043 , A61H2205/023 , A61H2205/024 , A61M31/00 , A61N1/0456 , A61N1/36014 , A61N1/36046 , A61N1/36071 , A61N1/36132 , A61N1/36146 , A61N1/3615 , A61N1/36171 , A61N1/36175 , A61N1/3787 , A61N7/00 , A61N2007/0043 , H02J7/0044
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
Abstract translation: 这里描述了通过向鼻腔或鼻窦组织提供刺激来治疗一种或多种病症（如干眼症）或改善眼部健康的装置，系统和方法。 通常，设备可以是手持式的或可植入的。 在一些变型中，手持装置可以具有刺激器主体和具有一个或多个鼻插入尖端的刺激器探针。 当装置和系统用于治疗干眼症时，可以刺激鼻或鼻窦组织以增加泪液产生，减少干眼症状和/或改善眼部表面的健康。
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公开(公告)号：US20240359004A1
公开(公告)日：2024-10-31
申请号：US18526307
申请日：2023-12-01
Applicant: Oculeve, Inc.
Inventor： Douglas Michael Ackermann , James Donald Loudin
IPC: A61N1/05 , A61F7/12 , A61H1/00 , A61H9/00 , A61H21/00 , A61H23/02 , A61M31/00 , A61N1/04 , A61N1/36 , A61N1/378 , A61N7/00 , H02J7/00
CPC classification number: A61N1/0546 , A61F7/12 , A61H1/00 , A61H9/0071 , A61H21/00 , A61H23/02 , A61H23/0218 , A61H23/0245 , A61H23/0263 , A61N1/0456 , A61N1/36014 , A61N1/36046 , A61N1/36071 , A61N1/36132 , A61N1/36146 , A61N1/3615 , A61N1/36171 , A61N1/36175 , A61N1/3787 , A61N7/00 , H02J7/0044 , A61H2201/0153 , A61H2201/0173 , A61H2201/0207 , A61H2201/0214 , A61H2201/025 , A61H2201/10 , A61H2201/165 , A61H2201/5002 , A61H2201/5005 , A61H2201/5015 , A61H2201/5035 , A61H2201/5038 , A61H2201/5043 , A61H2205/023 , A61H2205/024 , A61M31/00 , A61N2007/0043
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
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公开(公告)号：US20210370051A1
公开(公告)日：2021-12-02
申请号：US17164709
申请日：2021-02-01
Applicant: Oculeve Inc.
Inventor： James Donald Loudin , Daniel N. Hamilton , Manfred Franke , Douglas Michael Ackermann
Abstract: Described here are devices, systems, and methods for treating one or more conditions, such as allergic rhinitis, non-allergic rhinitis, nasal congestion, ocular allergy, and/or symptoms associated with these conditions, by providing stimulation to nasal or sinus tissue. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs, and the nasal insertion prongs may be configured to deliver an electrical stimulus to the tissue.
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公开(公告)号：US10967173B2
公开(公告)日：2021-04-06
申请号：US16852374
申请日：2020-04-17
Applicant: Oculeve, Inc.
Inventor： Douglas Michael Ackermann , James Donald Loudin
IPC: A61N1/05 , A61N1/36 , A61H1/00 , A61F7/12 , A61H9/00 , A61H21/00 , A61H23/02 , A61N1/378 , H02J7/00 , A61N1/04 , A61N7/00 , A61M31/00
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
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公开(公告)号：US10918864B2
公开(公告)日：2021-02-16
申请号：US15584956
申请日：2017-05-02
Applicant: Oculeve, Inc.
Inventor： Manfred Franke , Diane Michelle Senchyna , Daniel N. Hamilton
Abstract: Described here are devices, systems, and methods for treating meibomian gland disease and/or blepharitis by providing intranasal stimulation. Generally, the devices may deliver electrical stimulation to the nasal mucosa. Intranasal stimulation may unblock obstructed meibomian glands and increase the lipid content of tears, both acutely during stimulation and subsequent to intranasal stimulation. The methods may include an initial round of stimulation to unblock obstructed meibomian glands, and subsequent shorter rounds of stimulation to cause meibum secretion and maintain the open glands.
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Patent Agency Ranking
公开(公告)号：US20200238076A1
公开(公告)日：2020-07-30
申请号：US16852374
申请日：2020-04-17
Applicant: Oculeve, Inc.
Inventor： Douglas Michael Ackermann , James Donald Loudin
IPC: A61N1/05 , A61N1/36 , A61H1/00 , A61F7/12 , A61H9/00 , A61H21/00 , A61H23/02 , A61N1/378 , H02J7/00 , A61N1/04 , A61N7/00
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
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公开(公告)号：US20200030615A1
公开(公告)日：2020-01-30
申请号：US16595846
申请日：2019-10-08
Applicant: Oculeve, Inc.
Inventor： James Donald Loudin , Manfred Franke , Daniel N. Hamilton , Anand Doraiswamy , Douglas Michael Ackermann
Abstract: Described here are devices, systems, and methods for increasing tear production by stimulating the cornea, conjunctiva, and/or subconjunctiva. In some variations, the devices may be in the form of a contact lens. The contact lens may comprise a lens body and a stimulator chip, where the stimulator chip is embedded in the lens body. An external power source wirelessly transmits energy to the stimulator chip, where the stimulator chip may convert the energy to an electric waveform to stimulate the cornea, conjunctiva, and/or subconjunctiva. Stimulation may activate the lacrimal reflex to increase tear production. The devices and systems for increasing tear production may be used in methods of treating dry eye, reducing the symptoms of tired eye, increasing comfort for contact lens wearers, and extending the number of years a contact lens user can wear contacts. Also described are methods of manufacturing a contact lens.
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公开(公告)号：US10537469B2
公开(公告)日：2020-01-21
申请号：US15649364
申请日：2017-07-13
Applicant: Oculeve, Inc.
Inventor： Janusz Kuzma , Douglas Michael Ackermann , Christopher William Stivers
Abstract: Systems, devices, and methods for delivering an implant to the orbit. In some instances, the systems may include a delivery device having a tongue member and a handle. The delivery device may further include an ejector configured to deliver an implant from the tongue member. The delivery device may also include a piercing member configured to create an opening in tissue. The systems may further include a piercing member for creating an opening in tissue. In some instances, the piercing member may have a first blade member rotatably connected to a second blade member.
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公开(公告)号：US20190167978A1
公开(公告)日：2019-06-06
申请号：US16172615
申请日：2018-10-26
Applicant: Oculeve, Inc.
Inventor： Douglas Michael Ackermann , James Donald Loudin
IPC: A61N1/05 , A61N1/36 , A61N1/04 , A61H23/02 , A61N1/378 , A61N7/00 , A61H21/00 , H02J7/00 , A61H9/00 , A61F7/12 , A61H1/00
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
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公开(公告)号：USD826420S1
公开(公告)日：2018-08-21
申请号：US29562793
申请日：2016-04-28
Applicant: Oculeve, Inc.
Designer： Douglas Michael Ackermann , James Donald Loudin , John Wardle , John W. Lai , Natalie Catherine Vanns
Abstract: The design is the visual features of the NASAL STIMULATOR DEVICE shown in solid lines in the drawings, whether those features are of shape, configuration, ornament, or pattern, or are a combination of any of these features. Shading is used in the drawings to better illustrate the design. The portions of the article shown in stippled lines do not form part of the design.Drawings of the design are included.FIG. 1 is a front perspective view of the nasal stimulator device;FIG. 2 is a front elevation view thereof;FIG. 3 is a rear elevation view thereof;FIG. 4 is a right side elevation view thereof;FIG. 5 is a left side elevation view thereof;FIG. 6 is a top plan view thereof; andFIG. 7 is a bottom plan view thereof.
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