Abstract:
A binding domain polypeptide and fusion proteins thereof that recognize an IL6/IL6 receptor complex, as well as compositions and methods of use thereof.
Abstract:
Disclosed are methods, systems, apparatus, and products, including a method for operating a respiratory care device that includes collecting at a respiratory care device data representative of operation of the respiratory care device, and communicating to a computing-based device external to the respiratory care device at least some of the collected data to control the operability of the respiratory care device. In some embodiments, the method may further include communicating to the respiratory care device data to controllably change one or more operation parameters of the respiratory care device to cause a change in the operation of the respiratory care device, changing the operation parameters of the respiratory care device according to the communicated data, and communicating to the external computing-based device resultant data representative of operation of the respiratory care device resulting from the controllable change to the one or more operation parameters.
Abstract:
An enhanced system and method for executing options trades are disclosed. The lead market maker entitlements are integrated with sophisticated order types, including dark order types, so that the lead marker maker is guaranteed an allocation of the trade if the lead market maker is at the NBBO when an order priced at or better than the NBBO is received. The lead market maker is not provided an opportunity to price improve to execute with a specific incoming order. Additionally, market makers who are not the lead market maker in an option series may be granted the privileges of a lead market maker for the purpose of executing with a specific incoming directed order if the designated market maker is at the NBBO when a directed order priced at or better than the NBBO is received. The system and method disclosed encourages market makers to quote the best price possible, which in turn has the effect of narrowing spreads. Furthermore, as only displayed orders at the NBBO are eligible to execute ahead of market makers quoting at the NBBO, the system and method encourages users to display their best prices and sizes to the marketplace.
Abstract:
The present invention relates to constructs and methods for the treatment of diseases, disorders and conditions, including those relating to or involving autoimmune disorders, inflammation, bacterial, fungal, and viral infections, and diseases caused by or involving uncontrolled or abnormal proliferation of cells, including cancer.
Abstract:
A soybean variety designated 93B41, the plants and seeds of soybean variety 93B41, methods for producing a soybean plant produced by crossing the variety 93B41 with itself or with another soybean plant, and hybrid soybean seeds and plants produced by crossing the variety 93B41 with another soybean line or plant.
Abstract:
A monitoring tap for accessing signals on bus or tag coaxial cables used to convey signals between a CPU an external devices is described. A circuit board carrying termination resistors for the coaxial cables and high input isolation amplifiers is provided with an input connector that mates with the plug located in the slot that normally receives a terminator. The circuit board has an output connector coupled to the outputs of the isolation networks. A housing partially encloses the circuit board while enabling external access to the output connector. Several embodiments are described.
Abstract:
An absorbent core comprising a substrate layer and an absorbent layer, the absorbent layer comprising an absorbent material and a thermoplastic adhesive material; the absorbent core has longitudinal and transverse dimensions and consists of nine transverse segments in its longitudinal dimension and six longitudinal segments in its transverse dimension; in each of the transverse segments and longitudinal segments, the absorbent layer has average basis weights of absorbent material of thermoplastic adhesive material; the basis weights of the absorbent layer in at least one of the transverse segments are lower than the basis weights of the absorbent layer in at least one other of the transverse segments; and the basis weights of the absorbent layer in at least one of the longitudinal segments are lower than the basis weights of the absorbent layer in at least one other of the longitudinal segments.
Abstract:
Methods of producing a custom fitted prosthetic socket device for a residual limb include covering the distal end thereof with a liner, positioning the covered end within a socket cup to maintain a spaced relationship between the exterior of the liner and the interior of the socket cup, introducing an expandable, hardenable filler material into the socket cup, expanding the material to fill the volume between the liner and the socket cup, hardening the material, and removing the socket cup, hardened filler material, and liner, from the residual limb. Some methods include a filler material that hardens into a flexible solid foam cushioning layer, which may optionally form a bond between the socket cup and the liner, embedding the liner in the cushioning layer. Some methods include selecting a socket cup from a plurality of sized socket cups, and/or providing the plurality of sized socket cups.
Abstract:
Disclosed are devices, systems, and methods, including an oxygen delivery device that includes an oxygen delivery module, at least one sensor to detect patient breathing, and a controller configured to control the oxygen delivery module to cause the oxygen delivery module to deliver oxygen to the patient based on data from the at least one sensor such that in response to a determination, based on data from the at least one sensor, that no breathing is detected for a first pre-determined period of time, the controller causes the oxygen delivery module to deliver oxygen to the patient in continuous flow mode, and in response to a determination, based on additional data from the at least one sensor, that breathing is detected for a second period of time, the controller causes the oxygen delivery module to deliver oxygen to the patient in a pulse flow mode.