公开(公告)号：US08221488B2

公开(公告)日：2012-07-17

申请号：US12781373

申请日：2010-05-17

申请人： James D. Lewis ,  David J. Myers ,  Wayne D. House

发明人： James D. Lewis ,  David J. Myers ,  Wayne D. House

IPC分类号： A61M29/00

CPC分类号： A61F2/82 ,  A61F2/07 ,  A61F2/90 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2210/0014 ,  A61F2240/001 ,  A61L31/10 ,  C08L27/18

摘要： A method of making a tubular intraluminal graft in the form of a tubular diametrically adjustable stent having a tubular covering of porous expanded polytetrafluoroethylene which is less than 0.10 mm thick. The covering may be on the exterior surface of the stent, or on the interior surface of the stent, or both. The covering may be affixed to the stent by an adhesive which is preferably fluorinated ethylene propylene.

公开(公告)号：US20100217375A1

公开(公告)日：2010-08-26

申请号：US12781358

申请日：2010-05-17

申请人： James D. Lewis ,  David J. Myers ,  Wayne D. House

发明人： James D. Lewis ,  David J. Myers ,  Wayne D. House

IPC分类号： A61F2/06

CPC分类号： A61F2/82 ,  A61F2/07 ,  A61F2/90 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2210/0014 ,  A61F2240/001 ,  A61L31/10 ,  C08L27/18

摘要： A method of making an tubular intraluminal graft in the form of a tubular diametrically adjustable stent having a tubular covering of porous expanded PTFE which is less than 0.10 mm thick. The covering may be on the exterior surface of the stent, or on the interior surface of the stent, or both. The covering may be affixed to the stent by an adhesive which is preferably fluorinated ethylene propylene.

公开(公告)号：US07279208B1

公开(公告)日：2007-10-09

申请号：US09510937

申请日：2000-02-22

申请人： Donald G. M. Goffena ,  David J. Myers

发明人： Donald G. M. Goffena ,  David J. Myers

IPC分类号： B29D22/00 ,  B29D23/00 ,  B32B1/08

CPC分类号： B29D23/18 ,  A61B17/3431 ,  A61F2/06 ,  A61F2/07 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2250/0067 ,  A61L27/16 ,  A61L27/56 ,  A61L29/041 ,  A61L29/085 ,  A61L31/048 ,  A61L31/10 ,  B29C53/38 ,  B29C53/58 ,  B29C63/10 ,  B29C70/207 ,  B29C70/30 ,  B29D23/001 ,  B29K2027/18 ,  B29K2105/04 ,  B29K2105/048 ,  B29K2105/0827 ,  B29K2105/101 ,  B29K2305/12 ,  B29L2009/00 ,  B29L2022/022 ,  B29L2023/005 ,  B29L2023/007 ,  B29L2023/18 ,  B29L2031/14 ,  B29L2031/753 ,  B29L2031/7542 ,  B32B1/08 ,  B32B3/02 ,  B32B3/10 ,  B32B5/18 ,  B32B5/32 ,  B32B15/02 ,  B32B15/08 ,  B32B27/30 ,  F16L11/085 ,  Y10S623/90 ,  Y10T428/1352 ,  Y10T428/1355 ,  Y10T428/1362 ,  Y10T428/139 ,  Y10T428/1393 ,  Y10T428/1397 ,  Y10T428/31504 ,  Y10T428/3154 ,  Y10T428/31544 ,  C08L27/18

摘要： A thin-wall PTFE (polytetrafluoroethylene) tube in the form of a tube of porous expanded PTFE film wherein the porous PTFE film has a microstructure containing a multiplicity of fibrils. The thin-wall tube is used in a non-porous embodiment as the balloon portion of a balloon catheter. The thin-wall tube is not elastomeric; however, because of the thinness, strength and flexibility of the tube, it may be inserted into a body conduit in a collapsed state and then deployed from a catheter and inflated up to the maximum diameter of the thin-wall tube. The porous PTFE film is provided with a continuous layer of adhesive to provide the non-porous tube; the adhesive is preferably a thermoplastic and more preferably a thermoplastic fluoropolymer such as fluorinated ethylene propylene.

摘要翻译： 多孔PTFE多孔膜的形式的薄壁PTFE（聚四氟乙烯）管，其中多孔PTFE膜具有包含多个原纤维的微结构。 薄壁管用作非多孔实施例中的球囊导管的球囊部分。 薄壁管不弹性; 然而，由于管的薄度，强度和柔韧性，其可以以折叠状态插入体导管中，然后从导管展开并充气至薄壁管的最大直径。 多孔PTFE膜具有连续的粘合剂层以提供无孔管; 粘合剂优选为热塑性，更优选热塑性含氟聚合物，例如氟化乙烯丙烯。

公开(公告)号：US06704210B1

公开(公告)日：2004-03-09

申请号：US08993922

申请日：1997-12-18

申请人： David J. Myers

发明人： David J. Myers

IPC分类号： H01R909

CPC分类号： A61B17/07207 ,  A61B17/07292 ,  A61B2017/00238 ,  A61B2017/320052

摘要： A bioprosthesis sealing film strip is attached to a surgical stapler by passing a jaw of the stapler through openings formed in the ends of the strip. Following stapling the strip is released by making a cut from the opening to the edge of the strip. Alternatively, one end of the strip may be releasably secured to pins formed on the jaw.

摘要翻译： 生物假体密封膜条通过使吻合器的钳口通过形成在条的端部的开口而附接到外科缝合器。 在装订后，通过从开口到条边缘的切割来释放条带。 或者，条的一端可以可释放地固定到形成在钳口上的销。

公开(公告)号：US06547815B2

公开(公告)日：2003-04-15

申请号：US10083461

申请日：2002-02-25

申请人： David J. Myers

发明人： David J. Myers

IPC分类号： A61M2900

CPC分类号： A61F2/82 ,  A61F2/07 ,  A61F2/90 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2210/0014 ,  A61F2240/001 ,  A61L31/10 ,  C08L27/18

摘要： A tubular intraluminal graft in the form of a tubular diametrically adjustable stent having a tubular covering of porous expanded polytetrafluoroethylene which is less than 0.10 mm thick. The covering may be on the exterior surface of the stent, or on the interior surface of the stent, or both. The covering may be affixed to the stent by an adhesive which is preferably fluorinated ethylene propylene.

公开(公告)号：US06347632B1

公开(公告)日：2002-02-19

申请号：US07910970

申请日：1992-07-09

申请人： Carol E. Eberhardt ,  David J. Myers

发明人： Carol E. Eberhardt ,  David J. Myers

IPC分类号： A61B1900

CPC分类号： A61F2/2412

摘要： A method of creating a simulated aorta patterned from a natural aorta and having a preselected amount of compliance is disclosed. The dimensions of a simulated aortic root patterned according to the dimensions of a natural aorta are first selected and a mold provided. The amount of circumferential compliance desired in the simulated aorta is then selected, based on natural circumferential compliancies. A material such as silicone rubber formed of an elastomer and a filler is used to form the aorta, the durometer of the material being varied by varying the relative amount of the components, to provide the selected amount of circumferential compliance in a simulated aorta having the selected dimensions. The aorta is then formed curing the material in the mold for about 24 hours. Groups of simulated aortas so produced, sometimes having different sizes and/or compliancies are also disclosed. A method of testing non-stented valves using the aortas is included.

摘要翻译： 公开了一种创建从天然主动脉图案化并具有预选量的顺应性的模拟主动脉的方法。 首先选择根据天然主动脉的尺寸进行图案化的模拟主动脉根的尺寸，并提供模具。 然后根据天然圆周顺应性选择模拟主动脉期望的圆周顺应量。 使用由弹性体和填料形成的诸如硅橡胶的材料以形成主动脉，通过改变组件的相对量来改变材料的硬度，以在具有所述主动脉的模拟主动脉中提供选定量的圆周顺应性 所选尺寸。 然后使主动脉固化模具中的材料约24小时。 如此生产的模拟主动脉组，有时具有不同的尺寸和/或顺应性。 包括使用主动脉测试非支架瓣膜的方法。

公开(公告)号：US6159565A

公开(公告)日：2000-12-12

申请号：US108963

申请日：1993-08-18

申请人： Carey V. Campbell ,  James D. Lewis ,  David J. Myers

发明人： Carey V. Campbell ,  James D. Lewis ,  David J. Myers

IPC分类号： A61B17/34 ,  A61F2/00 ,  A61F2/06 ,  A61L29/04 ,  A61L29/08 ,  A61L31/04 ,  A61L31/10 ,  B29C53/38 ,  B29C53/58 ,  B29C70/20 ,  B29C70/30 ,  F16L11/08 ,  B29D22/00

CPC分类号： A61L31/048 ,  A61B17/3431 ,  A61F2/07 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2250/0067 ,  A61L29/041 ,  A61L29/085 ,  A61L31/10 ,  B29C53/38 ,  B29C53/58 ,  B29C70/207 ,  B29C70/30 ,  B29K2027/18 ,  B29K2105/04 ,  B29K2105/0827 ,  B29L2023/005 ,  B29L2031/7542 ,  F16L11/085 ,  Y10T428/13 ,  Y10T428/1328 ,  Y10T428/1352 ,  Y10T428/1369 ,  Y10T428/1379 ,  Y10T428/139 ,  Y10T428/1393 ,  Y10T428/1397 ,  Y10T428/31504 ,  Y10T428/31536 ,  Y10T428/3154 ,  Y10T428/31544 ,  C08L27/18

摘要： An intraluminal vascular graft in the form of a tube of porous expanded polytetrafluoroethylene film wherein the porous polytetrafluoroethylene film has a microstructure containing a multiplicity of fibrils oriented substantially parallel to each other. The tube has a wall thickness of less than about 0.25 mm and is made from at least one first layer and at least one second layer of porous polytetrafluoroethylene film, wherein the fibrils of the first and second layers are oriented substantially perpendicular to each other. Preferably the fibrils of the at least one first layer are oriented substantially parallel to the longitudinal axis of the tube and the fibrils of the at least one second layer of porous polytetrafluoroethylene film are oriented substantially circumferential to the tube. The first and second layers may be inner and outer layers respectively, or alternatively their relationship may be reversed. Alternatively, either of the first and second film layers may be replaced with alternative reinforcing components such as a braid or at least one reinforcing rib.

摘要翻译： 以多孔膨体聚四氟乙烯膜管形式的管腔内血管移植物，其中多孔聚四氟乙烯膜具有包含相互平行取向的多个原纤维的微结构。 该管具有小于约0.25mm的壁厚，并且由至少一个第一层和至少一层第二层多孔聚四氟乙烯膜制成，其中第一层和第二层的原纤维彼此基本垂直。 优选地，至少一个第一层的原纤维基本上平行于管的纵向轴线定向，并且至少一个第二层多孔聚四氟乙烯膜的原纤维基本上圆周地取向管。 第一层和第二层可以分别是内层和外层，或者它们的关系可以相反。 或者，第一和第二膜层中的任一个可以用替代的增强部件例如编织物或至少一个加强肋来代替。

公开(公告)号：US5993489A

公开(公告)日：1999-11-30

申请号：US024239

申请日：1998-02-17

申请人： James D. Lewis ,  David J. Myers

发明人： James D. Lewis ,  David J. Myers

IPC分类号： A61L27/00 ,  A61F2/00 ,  A61F2/82 ,  A61L31/10 ,  A61F2/06

CPC分类号： A61F2/82 ,  A61L31/10 ,  A61F2/07 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2240/001 ,  Y10T428/1352 ,  Y10T428/1369 ,  Y10T428/1376 ,  Y10T428/1397 ,  Y10T428/3154

摘要： A tubular intraluminal graft for repairing body conduits, made from at least one layer of porous expanded PTFE film that has a microstructure having fibrils oriented in at least two directions which are substantially perpendicular to each other. The tubular intraluminal graft has a wall thickness of less than about 0.25 mm and may have a longitudinally or helically oriented seamline. Additional reinforcing components such as reinforcing ribs or braids may also be provided.

摘要翻译： 一种用于修复身体管道的管状腔内移植物，其由至少一层多孔的PTFE多孔膜制成，所述PTFE膜具有基本上彼此垂直的至少两个方向上具有原纤维取向的微结构。 管状管腔内移植物具有小于约0.25mm的壁厚，并且可以具有纵向或螺旋形定向的接缝。 还可以提供附加的增强部件，例如加强筋或编织物。

公开(公告)号：US5716401A

公开(公告)日：1998-02-10

申请号：US566446

申请日：1995-12-01

申请人： Carol E. Eberhardt ,  David J. Myers ,  Robert A. Pinkul

发明人： Carol E. Eberhardt ,  David J. Myers ,  Robert A. Pinkul

IPC分类号： A61F2/24

CPC分类号： A61F2/2427 ,  A61F2/243 ,  A61F2/2439 ,  Y10S623/90

摘要： A holder for a prosthetic heart valve is disclosed. The holder, comprising a holder assembly disposed at the distal end of an elongate handle, includes a plurality of distally-projecting fingers adapted to engage the commissure posts of a stented prosthetic valve. The commissure-engaging fingers are movable in a radially-inward direction toward the longitudinal axis of the holder. A mechanism is provided for retaining the fingers in an inwardly-moved position. When the commissure posts of the valve are coupled to the fingers, inward movement of the fingers causes the commissure posts to be deflected inward with respect to the valve, improving the implanting surgeon's access to the valve's suture ring and surrounding tissue.

公开(公告)号：US5476510A

公开(公告)日：1995-12-19

申请号：US230658

申请日：1994-04-21

申请人： Carol E. Eberhardt ,  David J. Myers ,  Robert A. Pinkul

发明人： Carol E. Eberhardt ,  David J. Myers ,  Robert A. Pinkul

IPC分类号： A61F2/24

CPC分类号： A61F2/2427 ,  A61F2/243 ,  A61F2/2439 ,  Y10S623/90

摘要： A holder for a prosthetic heart valve is disclosed. The holder, comprising a holder assembly disposed at the distal end of an elongate handle, includes a plurality of distally-projecting fingers adapted to engage the commissure posts of a stented prosthetic valve. The commissure-engaging fingers are movable in a radially-inward direction toward the longitudinal axis of the holder. A mechanism is provided for retaining the fingers in an inwardly-moved position. When the commissure posts of the valve are coupled to the fingers, inward movement of the fingers causes the commissure posts to be deflected inward with respect to the valve, improving the implanting surgeon's access to the valve's suture ring and surrounding tissue.

摘要翻译： 公开了一种假体心脏瓣膜的支架。 包括设置在细长手柄的远端处的保持器组件的保持器包括适于接合支架假体瓣膜的连合柱的多个向远侧突出的指状物。 连合接合指状物可沿径向向内的方向朝向保持器的纵向轴线移动。 提供一种用于将手指保持在向内移动位置的机构。 当瓣膜的连合柱联接到手指时，手指的向内运动导致连合柱相对于瓣膜向内偏转，改善了植入外科医生进入瓣膜缝线环和周围组织的通路。